Journal of Perinatal Medicine最新文献_第3页

Standardizing cord clamping: bridging physiology and recommendations from leading societies. 标准化脐带夹紧：桥接生理学和来自领先社会的建议。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-04-02 DOI: 10.1515/jpm-2025-0010

Mishu Mangla, Poojitha Kalyani Kanikaram, Nireesha Bukke, Naina Kumar, Deepak Singla

引用次数: 0

Copy number variation sequencing detection technology for identifying fetuses with abnormal soft indicators: a comprehensive study. 拷贝数变异测序检测技术鉴别软指标异常胎儿的综合研究。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-24 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0449

Guangting Lu, Weiwu Liu

{"title":"Copy number variation sequencing detection technology for identifying fetuses with abnormal soft indicators: a comprehensive study.","authors":"Guangting Lu, Weiwu Liu","doi":"10.1515/jpm-2024-0449","DOIUrl":"10.1515/jpm-2024-0449","url":null,"abstract":"Objectives: This study aims to assess the value of copy number variation sequencing (CNV-seq) in prenatal diagnosis of abnormal ultrasound markers to reduce fetal birth defects.Methods: Between June 2021 and December 2022, Yulin Maternal and Child Health Care Hospital examined 295 pregnant women with abnormal ultrasound indicators. We were categorized by the number of abnormalities and age. Karyotype analysis and CNV-seq were conducted, and the CNV-seq detection rate was statistically analyzed.Results: CNV-seq detected abnormal chromosomes in 43 out of 295 pregnant women with abnormal fetal ultrasound soft indicators, resulting in a detection rate of 14.58 %, compared to 5.76 % with traditional karyotype analysis. CNV-seq identified all aneuploidy abnormalities found by karyotype analysis and an additional 5 abnormalities, increasing the detection rate by 1.69 %. However, CNV-seq missed one case of chromosome equilibrium translocation. The detection rate of CNV-seq in fetuses with Several abnormal soft indexes was 29.41 %, significantly higher than individual soft indexes (p<0.05). The study compared abnormality rates of single and multiple ultrasound soft markers in two age groups. Abnormal detection rates were 12.38 % for the younger group and 13.73 % for the older group, with no significant difference. However, the younger group had a significantly higher detection rate for multiple soft markers compared to the older group (χ2=5.517, p<0.05).Conclusions: CNV-seq technology is valuable for identifying fetuses with abnormal soft markers, guiding its future use in perinatal diagnosis and aiding clinical genetic counseling.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"338-349"},"PeriodicalIF":1.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI and early diagnostics: mapping fetal facial expressions through development, evolution, and 4D ultrasound. 人工智能与早期诊断：通过发育、进化和4D超声绘制胎儿面部表情。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-14 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0602

Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Mochammad Besari Adi Pramono, Milan Stanojevic, Asim Kurjak

{"title":"AI and early diagnostics: mapping fetal facial expressions through development, evolution, and 4D ultrasound.","authors":"Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Mochammad Besari Adi Pramono, Milan Stanojevic, Asim Kurjak","doi":"10.1515/jpm-2024-0602","DOIUrl":"10.1515/jpm-2024-0602","url":null,"abstract":"The development of facial musculature and expressions in the human fetus represents a critical intersection of developmental biology, neurology, and evolutionary anthropology, offering insights into early neurological and social development. Fetal facial expressions, shaped by Cranial Nerve VII, reflect evolutionary adaptations for nonverbal communication and exhibit minimal asymmetry in universal expressions. Advancements in 4D ultrasound imaging and artificial intelligence (AI) have introduced innovative methods for analyzing these movements, revealing their potential as diagnostic tools for neurodevelopmental disorders like Bell's Palsy and Ramsay Hunt Syndrome before birth. These technologies promise early interventions that could significantly improve neonatal outcomes. By integrating imaging, AI, and longitudinal studies, researchers propose a multidisciplinary approach to establish diagnostic criteria for fetal facial movements. However, translating these advancements into clinical practice requires addressing ethical and practical challenges, refining imaging and AI methodologies, and fostering interdisciplinary collaboration. The review highlights the universality of fetal expressions while emphasizing the importance of distinguishing typical variability from pathological markers. In conclusion, these findings suggest transformative potential for maternal-fetal medicine, paving the way for proactive strategies to manage neurodevelopmental risks. Focused research is essential to fully harness these innovations and establish a new frontier in perinatal science.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"263-285"},"PeriodicalIF":1.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trisomy 18 mosaicism - are we able to predict postnatal outcome by analysing the tissue-specific distribution? 18三体嵌合体-我们能够通过分析组织特异性分布来预测产后结果吗？

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-14 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0543

Iris Dressler-Steinbach, Miriam Kinzel, Holger Janke, Rainer Wimmer, Alexander Weichert, Rabih Chaoui, Lars Garten, André Weber, Stefan Verlohren, Wolfgang Henrich, Markus Stumm

引用次数: 0

A crisis in U.S. maternal healthcare: lessons from Europe for the U.S. 美国产妇保健危机：欧洲给美国的教训

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-06 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0606

Amos Grünebaum, Joachim Dudenhausen, Frank A Chervenak

引用次数: 0

Investigation of cardiac remodeling and cardiac function on fetuses conceived via artificial reproductive technologies: a review. 人工生殖技术胎儿心脏重构和心脏功能的研究进展。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-21 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0346

Konstantinos Tasias, Maria Papamichail, Zacharias Fasoulakis, Marianna Theodora, Georgios Daskalakis, Panos Antsaklis

{"title":"Investigation of cardiac remodeling and cardiac function on fetuses conceived via artificial reproductive technologies: a review.","authors":"Konstantinos Tasias, Maria Papamichail, Zacharias Fasoulakis, Marianna Theodora, Georgios Daskalakis, Panos Antsaklis","doi":"10.1515/jpm-2024-0346","DOIUrl":"10.1515/jpm-2024-0346","url":null,"abstract":"The prevalence of artificial reproductive technologies (ART), such as intra-uterine insemination (IUI), in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI), has surged in response to the global increase in infertility rates, now impacting 17.5 % of couples. With over nine million babies born through ART, the safety and efficacy of these methods are largely recognized; however, emerging concerns regarding their association with prenatal and long-term health risks, especially cardiovascular disease (CVD), necessitate a thorough examination. This review synthesizes recent findings on the cardiac remodeling observed in ART-conceived fetuses, highlighting the potential for sub-clinical dysfunction and subsequent cardiovascular anomalies that may extend into adolescence. It delves into the perinatal complications linked to ART and examines the contribution of the renin-angiotensin system, epigenetic modifications, and altered microRNA expressions to fetal cardiovascular development. The analysis further differentiates the cardiac effects of fresh vs. frozen ART cycles and investigates the enduring nature of these changes beyond birth. Addressing the elevated CVD risk among ART individuals, the review suggests proactive measures, including lifestyle adjustments initiated early in life, to mitigate potential adverse outcomes. It emphasizes the critical need for ongoing research and intervention strategies to safeguard the cardiovascular health of the increasing number of ART-conceived individuals.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"286-296"},"PeriodicalIF":1.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing achievability and reproducibility of pulsed wave Doppler and tissue Doppler myocardial performance index and spatiotemporal image correlation annular plane systolic excursion in the cardiac function assessment of normal pregnancies. 比较脉冲波多普勒和组织多普勒心肌功能指数及时空图像相关性环面收缩偏移在正常妊娠心功能评估中的可实现性和可重复性。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-14 Print Date: 2025-02-25 DOI: 10.1515/jpm-2023-0446

Avnet Hagai, Erenbourg Anna, Thomas Samantha, Yagel Simcha, Welsh Alec

{"title":"Comparing achievability and reproducibility of pulsed wave Doppler and tissue Doppler myocardial performance index and spatiotemporal image correlation annular plane systolic excursion in the cardiac function assessment of normal pregnancies.","authors":"Avnet Hagai, Erenbourg Anna, Thomas Samantha, Yagel Simcha, Welsh Alec","doi":"10.1515/jpm-2023-0446","DOIUrl":"10.1515/jpm-2023-0446","url":null,"abstract":"Objectives: Multiple techniques have been proposed for functional fetal cardiology, including pulsed-wave (PW) and tissue Doppler imaging (TDI), Myocardial Performance Index (MPI), annular plane systolic excursion (TAPSE/MAPSE) and spatiotemporal image correlation (STIC). We aimed to compare these techniques' achievability and reproducibility to determine their clinical utility for each cardiac side.Methods: Uncomplicated pregnancies from 22 to 39 weeks were recruited and images and volumes stored for offline analysis. PWD-MPI values were calculated using previously demonstrated automation algorithms, and the remaining volumes were evaluated by two experienced operators.Results: Seventy-nine women were scanned generating 222 volumes, with high achievability (>86 %) for all three modalities on both cardiac sides; highest for TAPSE/MAPSE (94 %). Repeatability (ICC) on the right side of the heart was highest for TAPSE (inter-observer 0.86; intraobserver 0.73), compared to PWD-MPI (0.69) and TDI-MPI (0.83). For the left side, repeatability was high for both PWD-MPI (0.80) and TDI-MPI (0.86) though low for MAPSE (inter-observer 0.7, intra-observer 0.69). There was poor correlation between PWD-MPI and TDI-MPI values.Conclusions: TAPSE appears most reliable for evaluation of right heart function, compared to PWD-MPI for the left. As TDI-MPI correlates poorly with PWD-MPI, the latter appears to be the functional tool of choice.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"196-204"},"PeriodicalIF":1.7,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The J ournal of P erinatal M edicine is switching its publication model to open access. 《产前医学杂志》正将其出版模式改为开放获取。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-13 Print Date: 2025-01-29 DOI: 10.1515/jpm-2025-0009

Joachim W Dudenhausen

引用次数: 0

Antepartum multidisciplinary approach improves postpartum pain scores in patients with opioid use disorder. 产前多学科方法改善阿片类药物使用障碍患者产后疼痛评分。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-13 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0358

Tiffany Yang, Emily Stetler, Diana Garretto, Kimberly Herrera, David Garry, Cassandra Heiselman

{"title":"Antepartum multidisciplinary approach improves postpartum pain scores in patients with opioid use disorder.","authors":"Tiffany Yang, Emily Stetler, Diana Garretto, Kimberly Herrera, David Garry, Cassandra Heiselman","doi":"10.1515/jpm-2024-0358","DOIUrl":"10.1515/jpm-2024-0358","url":null,"abstract":"Objectives: Pregnancies affected by opioid use disorder (OUD) face difficulties with postpartum pain control. This study aims to determine if prenatal anesthesia consultation for patients on medication for opioid use disorder (MOUD) affects maternal postpartum pain control.Methods: This is a retrospective cohort study of pregnant patients diagnosed on MOUD who received prenatal care and delivered at a single academic institution between January 2017 and July 2023. Subjects were divided into those who received prenatal anesthesia consultation and those who did not. Severe pain (numerical rating scale 0-10) was defined as score≥7. Statistical analysis was performed using Chi-square, Mann-Whitney U, and multivariable logistical regression tests with significance defined as p<0.05.Results: The cohort included 359 women on MOUD. Of these, 17.8 % (n=64) received anesthesia consultation and 82.2 % (n=295) did not. Factors found associated with receiving anesthesia consultation were prenatal care with an obstetric provider trained in maternal OUD (p<0.01), psychiatric diagnosis (p<0.01) and higher number of prenatal care visits (10.12 vs. 8.99, p=0.007). When comparing pain scores in the first 24 h postpartum, patients with prenatal anesthesia consultation had statistically significant lower rates of severe pain compared to those who did not (25 vs. 44.7 %, p=0.004). Anesthesia consultation (OR 0.34) and cesarean section (OR 2.81) were independent predictors of severe postpartum pain in the first 24 h after delivery.Conclusions: Patients on MOUD who received antenatal anesthesia consultation report lower postpartum pain scores than those without consultation, which supports that multidisciplinary care for pregnant patients with OUD may help the postpartum experience.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"327-331"},"PeriodicalIF":1.7,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adrenal gland size in fetuses with congenital heart disease. 先天性心脏病胎儿的肾上腺大小。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-07 Print Date: 2025-03-26 DOI: 10.1515/jpm-2024-0402

Kathleen M Oberste, Daniela Willy, Chiara de Santis, Mareike Möllers, Ralf Schmitz, Kathrin Oelmeier

{"title":"Adrenal gland size in fetuses with congenital heart disease.","authors":"Kathleen M Oberste, Daniela Willy, Chiara de Santis, Mareike Möllers, Ralf Schmitz, Kathrin Oelmeier","doi":"10.1515/jpm-2024-0402","DOIUrl":"10.1515/jpm-2024-0402","url":null,"abstract":"Objectives: The aim of this study was to compare the adrenal gland size of fetuses with congenital heart diseases (CHD) and normal fetuses.Methods: In this cross-sectional prospective study we measured the fetal adrenal gland size (total width, cortex width, medulla width, adrenal gland ratio of total width divided by medulla width) in 62 fetuses with CHD and 62 gestational-age-matched controls between 20 + 0 and 39 + 3 weeks of gestation. First, we clustered three CHD subgroups: CHD group_1 with a normal outflow tract (n=7), CHD group_2 with an altered outflow tract and anterograde flow in the ascending aorta (n=39) and CHD group_3 with an altered outflow tract and retrograde flow in the ascending aorta (n=16). In a second step, we summed up all CHD cases with outflow tract anomalies to CHD group_2 + 3 (n=55). Each group was compared to their matched controls.Results: Prenatally, fetuses affected by CHD with outflow tract alterations show an elevated adrenal gland ratio (total width/medulla width) compared to normal fetuses (p<0.001). This finding applies to both subgroups of outflow tract alterations with anterograde (p<0.001) and retrograde perfusion of the ascending aorta (p<0.001).Conclusions: Fetuses affected by CHD with an altered outflow tract show a relatively larger cortex of the adrenal gland compared to normal fetuses. The results of this study suggest that haemodynamic changes during fetal maturation cause an elevated metabolic stress level that may be responsible for an enlarged adrenal gland ratio.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"387-393"},"PeriodicalIF":1.7,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0