Journal of Perinatal Medicine最新文献_第2页

Hematological indicators and their impact on maternal and neonatal outcomes in pregnancies with thalassemia traits.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-03-17 DOI: 10.1515/jpm-2024-0394

Ratana Meng, Hai-Ning Bi, Chanrith Mork, Ji-Fang Shi

{"title":"Hematological indicators and their impact on maternal and neonatal outcomes in pregnancies with thalassemia traits.","authors":"Ratana Meng, Hai-Ning Bi, Chanrith Mork, Ji-Fang Shi","doi":"10.1515/jpm-2024-0394","DOIUrl":"https://doi.org/10.1515/jpm-2024-0394","url":null,"abstract":"Objectives: The aim of this study is to compare the obstetric, neonatal, and hematological indicators of pregnant women with thalassemia traits with those of pregnant women without such traits.Methods: This retrospective cohort study was conducted from January 2017 to October 2023 at the Department of Obstetrics and Gynecology, The First Affiliated Hospital of Dali University. The study included 185 cases of thalassemia traits and 185 control cases. Data were analysis using the SPSS program (Version 27.0).Results: Significant differences were observed in gravidity and parity histories (p<0.05). Significant differences were also observed in the rates of gestational diabetes mellitus (GDM), hypertensive disorder of pregnancy (HDP), cesarean delivery, adherent placenta, and anemia in the second and third trimesters following the number of RR (95 % CI): 2.182 (1.101-4.324), 9.000 (1.152-70.325), 2.091 (1.555-2.811), 3.401 (1.280-9.009), 4.222 (2.102-8.481), and 2.053 (1.476-2.855), respectively (p<0.05). However, no significant differences were noted in the rates of preterm birth, low birth weight, macrosomia, intrauterine growth restriction, fetal distress, fetal malformation, and stillbirth (p>0.05). Furthermore, significant differences were noted in the levels of hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and red cell distribution width (RDW) during the first, second, and third trimesters (p<0.05).Conclusions: As pregnancy progresses, the levels of Hb tend to decrease, while the MCH and RDW levels increase. On the other hand, the level of MCV remain the same overtime. Thalassemia traits are significantly associated with anemia during pregnancy, particularly in the second and third trimesters. Furthermore, thalassemia traits are related to an increased incidence of GDM, HDP, and cesarean delivery.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility and reproducibility of speckle tracking echocardiography in routine assessment of the fetal heart in a low-risk population.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-25 DOI: 10.1515/jpm-2024-0514

Adalina Sacco, Ayisha Kazi, Diane Nzelu, Victoria Jowett, Pranav Pandya

{"title":"Feasibility and reproducibility of speckle tracking echocardiography in routine assessment of the fetal heart in a low-risk population.","authors":"Adalina Sacco, Ayisha Kazi, Diane Nzelu, Victoria Jowett, Pranav Pandya","doi":"10.1515/jpm-2024-0514","DOIUrl":"10.1515/jpm-2024-0514","url":null,"abstract":"Objectives: The objective of this study was to evaluate the feasibility and reproducibility of speckle tracking echocardiography (STE) in routine fetal cardiac assessments by non-cardiac experts in an NHS clinical setting.Methods: A prospective longitudinal cohort study was performed from April 2022 to June 2023. During all ultrasound scans between 18 and 40 weeks' gestation a 3 s cineloop of the fetal four chamber view was stored. Parameters of global cardiac function were analysed off-line using STE software by two researchers independently.Results: Of 393 ultrasound scans performed in fetuses fulfilling criteria, 50.9 % were able to be analysed using STE. Intraobserver variability was poor to moderate for both operators (Operator 1 correlation coefficient for FAC 0.28, EF 0.17, SV 0.01, SV/kg 0.00, CO 0.74, CO/kg 0.39; Operator two correlation coefficient for FAC 0.58, EF 0.65, SV 0.67, SV/kg 0.02, CO 0.66, CO/kg 0.31). Interobserver variability was also poor to moderate (Operator 1 vs. Operator two correlation coefficient for FAC 0.01, EF 0.00, SV 0.00, SV/kg 0.00, CO 0.64, CO/kg 0.25; Operator 2 vs. Operator 1 correlation coefficient for FAC 0.16, EF 0.06, SV 0.72, SV/kg 0.008, CO 0.70, CO/kg 0.34).Conclusions: Routine speckle tracking echocardiography of global cardiac function by non-cardiac experts in low-risk fetuses has low to moderate feasibility and reproducibility in a real-world NHS setting. A high grade of expertise is likely necessary to use STE in order to achieve high reproducibility. Future research should investigate factors contributing to variability in STE measurements and standardisation of protocols.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI and early diagnostics: mapping fetal facial expressions through development, evolution, and 4D ultrasound.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-14 DOI: 10.1515/jpm-2024-0602

Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Mochammad Besari Adi Pramono, Milan Stanojevic, Asim Kurjak

{"title":"AI and early diagnostics: mapping fetal facial expressions through development, evolution, and 4D ultrasound.","authors":"Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Mochammad Besari Adi Pramono, Milan Stanojevic, Asim Kurjak","doi":"10.1515/jpm-2024-0602","DOIUrl":"https://doi.org/10.1515/jpm-2024-0602","url":null,"abstract":"The development of facial musculature and expressions in the human fetus represents a critical intersection of developmental biology, neurology, and evolutionary anthropology, offering insights into early neurological and social development. Fetal facial expressions, shaped by Cranial Nerve VII, reflect evolutionary adaptations for nonverbal communication and exhibit minimal asymmetry in universal expressions. Advancements in 4D ultrasound imaging and artificial intelligence (AI) have introduced innovative methods for analyzing these movements, revealing their potential as diagnostic tools for neurodevelopmental disorders like Bell's Palsy and Ramsay Hunt Syndrome before birth. These technologies promise early interventions that could significantly improve neonatal outcomes. By integrating imaging, AI, and longitudinal studies, researchers propose a multidisciplinary approach to establish diagnostic criteria for fetal facial movements. However, translating these advancements into clinical practice requires addressing ethical and practical challenges, refining imaging and AI methodologies, and fostering interdisciplinary collaboration. The review highlights the universality of fetal expressions while emphasizing the importance of distinguishing typical variability from pathological markers. In conclusion, these findings suggest transformative potential for maternal-fetal medicine, paving the way for proactive strategies to manage neurodevelopmental risks. Focused research is essential to fully harness these innovations and establish a new frontier in perinatal science.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trisomy 18 mosaicism - are we able to predict postnatal outcome by analysing the tissue-specific distribution?

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-14 DOI: 10.1515/jpm-2024-0543

Iris Dressler-Steinbach, Miriam Kinzel, Holger Janke, Rainer Wimmer, Alexander Weichert, Rabih Chaoui, Lars Garten, André Weber, Stefan Verlohren, Wolfgang Henrich, Markus Stumm

引用次数: 0

Risk factors and outcomes of uterine rupture before onset of labor vs. during labor: a multicenter study.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-13 DOI: 10.1515/jpm-2024-0309

Qingwen Nie, Shujuan Luo, Bingjun Chen, Lu Wang, Fang He

{"title":"Risk factors and outcomes of uterine rupture before onset of labor vs. during labor: a multicenter study.","authors":"Qingwen Nie, Shujuan Luo, Bingjun Chen, Lu Wang, Fang He","doi":"10.1515/jpm-2024-0309","DOIUrl":"10.1515/jpm-2024-0309","url":null,"abstract":"Objectives: This study aims to reveal the distinctions between uterine rupture (UR) that occurs before onset of labor and during labor.Methods: This multicenter study was conducted across three tertiary hospitals in South China involving obstetrical UR from January 2009 to April 2022. Cases were categorized into two groups based on the timing of UR: prelabor and labor.Results: Among the cases of UR, 42 were classified in the prelabor group, and 27 in the labor group. The prelabor group had a higher prevalence of histories of myomectomies, ectopic pregnancy surgeries, congenital uterine anomalies, and prior URs. Among these ruptures, 45.2 % were located at cesarean section (CS) scars, compared to 81.5 % of cases during labor. Ruptures before onset of labor occurred across all gestational intervals, whereas those during labor, except one, occurred after 32 weeks. The median gestational age was 33 and 39 weeks in each group. Notably, prelabor cases demonstrated longer symptom-to-delivery intervals. Placenta percreta was more common in the prelabor group (16.7 vs. 3.7 % in the labor group). Among labor-related cases, 16 of the 27 occurred during trial of labor after cesarean (TOLAC), and four were identified following vaginal birth after cesarean (VBAC).Conclusions: URs differ by timing relative to labor. Ruptures before onset of labor more often resulted from scars other than CS and placenta percreta, occurring at earlier gestational weeks. This finding highlighted challenges in diagnosis and management. In contrast, ruptures during labor mostly occurred after 32 weeks and were strongly associated with TOLAC/VBAC.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The reference ranges for fetal ductus venosus flow velocities and calculated waveform indices and their predictive values for right heart diseases.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-06 DOI: 10.1515/jpm-2024-0577

Jian Wu, Yanping Ruan, Xinru Gao, Hairui Wang, Yuxuan Guan, Xiaoyan Hao, Jiancheng Han, Xiaoyan Gu, Yihua He

{"title":"The reference ranges for fetal ductus venosus flow velocities and calculated waveform indices and their predictive values for right heart diseases.","authors":"Jian Wu, Yanping Ruan, Xinru Gao, Hairui Wang, Yuxuan Guan, Xiaoyan Hao, Jiancheng Han, Xiaoyan Gu, Yihua He","doi":"10.1515/jpm-2024-0577","DOIUrl":"10.1515/jpm-2024-0577","url":null,"abstract":"Objectives: This study endeavors to establish comprehensive normal reference ranges and Z score formulas for ductus venosus (DV) flow velocity parameters and calculated waveform indices across different gestational ages in low-risk fetuses. Furthermore, we aim to validate the predictive capabilities of these Z score calculation formulas in fetuses with diverse right heart diseases.Methods: 8,953 singleton low-risk fetuses and 70 fetuses diagnosed with different types of right heart diseases were retrospectively enrolled. The DV blood flow velocities during the cardiac cycle (ventricular systolic wave velocity [S], ventricular diastolic wave velocity [D], atrial contraction wave velocity [A], and time-averaged maximum velocity [Tamx]) and calculated waveform indices (preload index [PLI], peak velocity index [PVI], pulsatility index [PI], S/A, and S/D) were obtained. Ninety low-risk fetuses were randomly selected as the control group to verify the predictive value of the Z score model for fetuses with different types of right heart diseases.Results: As gestational age increased (16-39 weeks), the mean values of S, D, A, and Tamx progressively increased; conversely, the mean values of PLI, PVI, PI, and S/A decreased, respectively, and the median value of S/D remained stable. The Z score-transformed A, PLI, PVI, PI, and S/A could serve as predictors of overall right heart diseases. Different DV Doppler parameter Z scores exhibited varying predictive values for different subtypes of right heart diseases.Conclusions: Normal reference ranges and corresponding Z score calculation formulas for DV hemodynamic parameters were established, which have demonstrated significant diagnostic values in identifying right heart diseases.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A crisis in U.S. maternal healthcare: lessons from Europe for the U.S.

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-02-06 DOI: 10.1515/jpm-2024-0606

Amos Grünebaum, Joachim Dudenhausen, Frank A Chervenak

引用次数: 0

Investigation of cardiac remodeling and cardiac function on fetuses conceived via artificial reproductive technologies: a review. 人工生殖技术胎儿心脏重构和心脏功能的研究进展。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-21 DOI: 10.1515/jpm-2024-0346

Konstantinos Tasias, Maria Papamichail, Zacharias Fasoulakis, Marianna Theodora, Georgios Daskalakis, Panos Antsaklis

{"title":"Investigation of cardiac remodeling and cardiac function on fetuses conceived via artificial reproductive technologies: a review.","authors":"Konstantinos Tasias, Maria Papamichail, Zacharias Fasoulakis, Marianna Theodora, Georgios Daskalakis, Panos Antsaklis","doi":"10.1515/jpm-2024-0346","DOIUrl":"https://doi.org/10.1515/jpm-2024-0346","url":null,"abstract":"The prevalence of artificial reproductive technologies (ART), such as intra-uterine insemination (IUI), in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI), has surged in response to the global increase in infertility rates, now impacting 17.5 % of couples. With over nine million babies born through ART, the safety and efficacy of these methods are largely recognized; however, emerging concerns regarding their association with prenatal and long-term health risks, especially cardiovascular disease (CVD), necessitate a thorough examination. This review synthesizes recent findings on the cardiac remodeling observed in ART-conceived fetuses, highlighting the potential for sub-clinical dysfunction and subsequent cardiovascular anomalies that may extend into adolescence. It delves into the perinatal complications linked to ART and examines the contribution of the Renin-Angiotensin System, epigenetic modifications, and altered microRNA expressions to fetal cardiovascular development. The analysis further differentiates the cardiac effects of fresh vs. frozen ART cycles and investigates the enduring nature of these changes beyond birth. Addressing the elevated CVD risk among ART individuals, the review suggests proactive measures, including lifestyle adjustments initiated early in life, to mitigate potential adverse outcomes. It emphasizes the critical need for ongoing research and intervention strategies to safeguard the cardiovascular health of the increasing number of ART-conceived individuals.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing achievability and reproducibility of pulsed wave Doppler and tissue Doppler myocardial performance index and spatiotemporal image correlation annular plane systolic excursion in the cardiac function assessment of normal pregnancies. 比较脉冲波多普勒和组织多普勒心肌功能指数及时空图像相关性环面收缩偏移在正常妊娠心功能评估中的可实现性和可重复性。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-14 Print Date: 2025-02-25 DOI: 10.1515/jpm-2023-0446

Avnet Hagai, Erenbourg Anna, Thomas Samantha, Yagel Simcha, Welsh Alec

{"title":"Comparing achievability and reproducibility of pulsed wave Doppler and tissue Doppler myocardial performance index and spatiotemporal image correlation annular plane systolic excursion in the cardiac function assessment of normal pregnancies.","authors":"Avnet Hagai, Erenbourg Anna, Thomas Samantha, Yagel Simcha, Welsh Alec","doi":"10.1515/jpm-2023-0446","DOIUrl":"10.1515/jpm-2023-0446","url":null,"abstract":"Objectives: Multiple techniques have been proposed for functional fetal cardiology, including pulsed-wave (PW) and tissue Doppler imaging (TDI), Myocardial Performance Index (MPI), annular plane systolic excursion (TAPSE/MAPSE) and spatiotemporal image correlation (STIC). We aimed to compare these techniques' achievability and reproducibility to determine their clinical utility for each cardiac side.Methods: Uncomplicated pregnancies from 22 to 39 weeks were recruited and images and volumes stored for offline analysis. PWD-MPI values were calculated using previously demonstrated automation algorithms, and the remaining volumes were evaluated by two experienced operators.Results: Seventy-nine women were scanned generating 222 volumes, with high achievability (>86 %) for all three modalities on both cardiac sides; highest for TAPSE/MAPSE (94 %). Repeatability (ICC) on the right side of the heart was highest for TAPSE (inter-observer 0.86; intraobserver 0.73), compared to PWD-MPI (0.69) and TDI-MPI (0.83). For the left side, repeatability was high for both PWD-MPI (0.80) and TDI-MPI (0.86) though low for MAPSE (inter-observer 0.7, intra-observer 0.69). There was poor correlation between PWD-MPI and TDI-MPI values.Conclusions: TAPSE appears most reliable for evaluation of right heart function, compared to PWD-MPI for the left. As TDI-MPI correlates poorly with PWD-MPI, the latter appears to be the functional tool of choice.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":"196-204"},"PeriodicalIF":1.7,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The J ournal of P erinatal M edicine is switching its publication model to open access. 《产前医学杂志》正将其出版模式改为开放获取。

IF 1.7 4区医学

Journal of Perinatal Medicine Pub Date : 2025-01-13 Print Date: 2025-01-29 DOI: 10.1515/jpm-2025-0009

Joachim W Dudenhausen

引用次数: 0