Journal of Perinatal Medicine最新文献

Stillbirth as a global public health issue: the need for a coordinated national approach in Germany. 死产作为一个全球公共卫生问题：德国需要采取协调一致的国家办法。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-05-08 DOI: 10.1515/jpm-2026-0137

Amira Göpfrich, Peter Bartmann, Joachim W Dudenhausen, Günther Heller, Brigitte Strizek, Tanja Groten, Lars Hellmeyer, Josefine Königbauer

引用次数: 0

Optimal management of pregnancies presenting with membrane prolapse. 膜脱垂妊娠的最佳处理。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-05-07 DOI: 10.1515/jpm-2026-0065

Dimitris Baroutis, Eleni Katsianou, Antonia Varthaliti, Aikaterini-Gavriela Giannakaki, Konstantinos Koukoumpanis, Nikolaos Sindos, Vasilios Lygizos, Ioannis Fragiskos, Michael Sindos, George Daskalakis, Panagiotis Antsaklis

{"title":"Optimal management of pregnancies presenting with membrane prolapse.","authors":"Dimitris Baroutis, Eleni Katsianou, Antonia Varthaliti, Aikaterini-Gavriela Giannakaki, Konstantinos Koukoumpanis, Nikolaos Sindos, Vasilios Lygizos, Ioannis Fragiskos, Michael Sindos, George Daskalakis, Panagiotis Antsaklis","doi":"10.1515/jpm-2026-0065","DOIUrl":"https://doi.org/10.1515/jpm-2026-0065","url":null,"abstract":"Introduction: Membrane prolapse represents a severe manifestation of cervical insufficiency, occurring in 0.3-1.0 % of pregnancies and posing significant risks for extreme prematurity and perinatal mortality. Despite decades of clinical experience, optimal management remains controversial.Content: This narrative review synthesizes current evidence on pathophysiology, diagnosis, and management of membrane prolapse. We examine biomechanical and inflammatory mechanisms, diagnostic criteria, including cervical length assessment and amniocentesis, as well as therapeutic strategies, such as emergency cerclage and expectant management. Evidence-based perioperative care includes prophylactic antibiotics (cefazolin plus azithromycin), tocolytic therapy for uterine quiescence, antenatal corticosteroids (betamethasone or dexamethasone) between 24 and 34 weeks, and magnesium sulfate for fetal neuroprotection before 32 weeks.Summary: Emergency cerclage achieves fetal survival rates of approximately 73 % in carefully selected patients presenting between 16 and 24 weeks with cervical dilation of 2-4 cm and absence of intraamniotic infection. Amniocentesis is critical when cervical dilation exceeds 2-3 cm, as infection represents the strongest predictor of treatment failure. Outcomes vary significantly based on clinical presentation, with negative amniocentesis associated with 70-80 % survival vs. 20-30 % with positive results.Outlook: Future research priorities include prospective randomized trials comparing emergency cerclage to expectant management, validation of biomarkers predicting infection and treatment success, optimization of perioperative protocols, and further development of innovative therapeutic strategies such as anti-inflammatory agents.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An audit of delivery plans for babies with antenatal urinary tract abnormalities: the mothers' perspective. 产前尿路异常婴儿的分娩计划审计：母亲的观点。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-05-07 DOI: 10.1515/jpm-2025-0579

Patrick Green, Agnes Ndzi, Giles Carey, Anthonia Adefolaju, Umber Agarwal, Harriet J Corbett

{"title":"An audit of delivery plans for babies with antenatal urinary tract abnormalities: the mothers' perspective.","authors":"Patrick Green, Agnes Ndzi, Giles Carey, Anthonia Adefolaju, Umber Agarwal, Harriet J Corbett","doi":"10.1515/jpm-2025-0579","DOIUrl":"https://doi.org/10.1515/jpm-2025-0579","url":null,"abstract":"Objectives: There is little evidence guiding the delivery of babies who are antenatally detected to have antenatal urinary tract abnormalities (AN-UTA), and some clinicians would deliver early purely because of AN-UTA. With growing evidence of adverse events resulting from early-term delivery this study aimed to assess delivery patterns for babies with AN-UTA.Methods: Parents of children referred to our service with AN-UTA from May 2022- Sept 2023 were asked about their recollection of delivery discussions and methods. Data were collected on antenatal scans, delivery timing and method and then subsequent urological investigations and management were assessed.Results: Seventy-two babies (53 male) were included. 22 (31 %) were born via spontaneous labour and delivery, 33 underwent planned delivery for non-urological reasons and 17 (24 %) had planned delivery purely because of their AN-UTA. 11/17 of these were before 39 weeks (early-term). 3/17 (18 %) underwent emergency caesarean section for failure to progress during early induction. There was no significant difference between babies born early for AN-UTA with regards to urgent urological investigations (36 % vs. 16 %, p=0.207), nor for early surgery (27 % vs. 10 %, p=0.134).Conclusions: 24 % of babies had planned delivery purely for their AN-UTA, without any change to their urological management. The majority of these were <39 weeks gestation. In the absence of other maternal/fetal concerns, delivery <39 weeks should be avoided to optimise global outcomes.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Balloon tamponade use in postpartum hemorrhage due to uterine atony: a retrospective study. 气囊填塞在子宫张力性产后出血中的应用：一项回顾性研究。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-05-04 DOI: 10.1515/jpm-2025-0388

Gulcan Okutucu, Duygu Tugrul Ersak, Hakki Serbetci, Ozgecan Ucyildiz, Ayse Gulcin Bastemur, Atakan Tanacan, Fatma Doga Ocal, Dilek Sahin

{"title":"Balloon tamponade use in postpartum hemorrhage due to uterine atony: a retrospective study.","authors":"Gulcan Okutucu, Duygu Tugrul Ersak, Hakki Serbetci, Ozgecan Ucyildiz, Ayse Gulcin Bastemur, Atakan Tanacan, Fatma Doga Ocal, Dilek Sahin","doi":"10.1515/jpm-2025-0388","DOIUrl":"https://doi.org/10.1515/jpm-2025-0388","url":null,"abstract":"Objectives: To investigate the influence of technical and clinical variations in uterine balloon tamponade (UBT) procedures on postpartum blood loss and maternal outcomes in women of postpartum hemorrhage (PPH) due to uterine atony.Methods: This retrospective cross-sectional study was conducted on 63 patients who underwent UBT for atonic PPH between January 2020 and March 2025. Data collected included demographic characteristics, uterine balloon inflation volume, timing and duration of insertion, and maternal outcomes. The primary outcomes were success of UBT and occurrence of composite adverse maternal outcomes (CAMO). ROC analysis was used to identify optimal threshold values for procedural variables.Results: UBT successfully controlled hemorrhage in 74.6 % of women. CAMO occurred in 17.5 % of patients. Severe PPH was observed in 60.3 % of women and was significantly associated with higher maternal shock index, increased transfusion requirements, and longer ICU stays. A delay of ≥45 min from delivery to UBT insertion was strongly associated with increased blood loss and higher CAMO incidence (AUC 0.858, p<0.001). Though not independently indicative of adverse outcomes, balloon volumes greater than 232.5 mL were associated with increased estimated blood loss (p=0.021). Duration of balloon retention and deflation timing had no significant impact on clinical outcomes.Conclusions: UBT is an effective intervention for controlling PPH secondary to uterine atony. Early application, within 45 min postpartum, is critical in reducing blood loss and maternal morbidity. Inflation volume may reflect bleeding severity but does not correlate with adverse outcomes. Findings support prompt and standardized application of UBT in PPH protocols.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal units' visiting policies and parental experience of open-access. 新生儿就诊政策与开放访问的家长体验。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-05-04 DOI: 10.1515/jpm-2025-0483

Charlotte Neske, Carolina Zorro, Valentina Fragala, Sandeep Shetty, Ana Serrano-Llop, Laura De-Rooy, Nicola Crowley, Ravindra Bhat, Rashmi Gandhi, Anne Greenough

{"title":"Neonatal units' visiting policies and parental experience of open-access.","authors":"Charlotte Neske, Carolina Zorro, Valentina Fragala, Sandeep Shetty, Ana Serrano-Llop, Laura De-Rooy, Nicola Crowley, Ravindra Bhat, Rashmi Gandhi, Anne Greenough","doi":"10.1515/jpm-2025-0483","DOIUrl":"https://doi.org/10.1515/jpm-2025-0483","url":null,"abstract":"Objectives: A survey of visiting policies in neonatal units in the UK and Ireland was conducted and parental experiences with open-access were examined across two neonatal units (one recently introduced it; another has had it in place for five years).Methods: Units were contacted by email or telephone to complete the survey. Parents at two units prospectively completed a questionnaire.Results: Eighty percent (169/212) of units participated in the survey. Among these, 88 % implemented complete open-access for parents, 7 % partial and 5 % restricted. 141/169 units (83.4 %) allowed parents during bedside ward rounds. Of these, 26 (18.4 %) required use of noise-cancelling headphones. Two persons per patient were allowed in 106 units (63 %), three in 44 (26 %) and four or more in 19 (11 %). Visitors must be accompanied by a parent. Siblings could visit at any time in 112 units (66 %), 48 during fixed hours (28 %) and 9 never allowed them (5 %); two units allowed siblings during summer months (1 %). In the two units, 87 % of 15 and 89 % of 20 parents were satisfied with the level of access. Concerns about confidentiality were expressed by 13 % and 20 % reported feeling a little worried about overhearing others' information or vice versa. Parents benefitted from open-access by feeling more welcome, less stressed and able to plan their visits more seamlessly. Open-access was perceived to improve the babies' quality of care through greater parental involvement and time spent together.Conclusions: Visiting policies varied between units; open-access was regarded as beneficial to parent and infant wellbeing.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal vaccination in the immunization era: implementation, uptake, and emerging vaccines. 免疫时代的孕产妇疫苗接种：实施、吸收和新出现的疫苗

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-04-27 DOI: 10.1515/jpm-2025-0714

Antônio Braga, Susana Cristina Aidé Viviani Fialho, Caroline Alves de Oliveira Martins, Karine Mello Duvivier, Gustavo Yano Callado, Edward Araujo Júnior, Jorge de Rezende-Filho

{"title":"Maternal vaccination in the immunization era: implementation, uptake, and emerging vaccines.","authors":"Antônio Braga, Susana Cristina Aidé Viviani Fialho, Caroline Alves de Oliveira Martins, Karine Mello Duvivier, Gustavo Yano Callado, Edward Araujo Júnior, Jorge de Rezende-Filho","doi":"10.1515/jpm-2025-0714","DOIUrl":"https://doi.org/10.1515/jpm-2025-0714","url":null,"abstract":"Maternal immunization has ascended as a cornerstone of contemporary strategies aimed at safeguarding pregnant women, fetuses, and children in early childhood against vaccine-preventable diseases. The profound physiological and immunological adaptations inherent to gestation heighten maternal susceptibility to infectious morbidity, while several pathogens, including influenza, pertussis, COVID-19, rubella, and respiratory syncytial virus (RSV), pose significant risks of adverse maternal, fetal, and neonatal outcomes. Although an extensive body of evidence attests to the safety and effectiveness of maternal vaccines, global uptake among pregnant people remains markedly uneven and, in many settings, critically suboptimal. A nuanced understanding of national and international immunization programs, along with their structural and sociocultural challenges, is imperative to strengthen perinatal health protection. This narrative review synthesizes evidence drawn from peer-reviewed scientific literature, global health agency publications, and official national immunization guidelines. Extracted data were complemented by analyses of the immunological landscape of pregnancy, current vaccine recommendations, established safety profiles, and maternal immunization schedules across high-, middle-, and low-income countries. Particular emphasis was placed on the vaccines most consistently recommended during pregnancy, namely influenza, Tdap, COVID-19, and RSV, as well as on contextual determinants influencing vaccine hesitancy, access barriers, and global disparities in coverage.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Z-score for the ductal flow pulsatility index in normal fetuses using two-dimensional Doppler echocardiography. 利用二维多普勒超声心动图建立正常胎儿导管血流脉搏指数z -评分。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-04-27 DOI: 10.1515/jpm-2025-0660

Luciane Alves da Rocha Amorim, Julia Castro Rodrigues, Paulo Zielinsky, Antonio Braga, Gustavo Yano Callado, Pedro Teixeira Castro, Edward Araujo Júnior

{"title":"Development of a Z-score for the ductal flow pulsatility index in normal fetuses using two-dimensional Doppler echocardiography.","authors":"Luciane Alves da Rocha Amorim, Julia Castro Rodrigues, Paulo Zielinsky, Antonio Braga, Gustavo Yano Callado, Pedro Teixeira Castro, Edward Araujo Júnior","doi":"10.1515/jpm-2025-0660","DOIUrl":"https://doi.org/10.1515/jpm-2025-0660","url":null,"abstract":"Objectives: To determine gestational age-specific reference ranges and develop a Z-score equation for the fetal ductal pulsatility index (PI), between 24 and 33 + 6 weeks of gestation.Methods: A prospective cross-sectional study conducted from 2023 to 2024, 226 singleton fetuses between 24 and 33 + 6 weeks were enrolled. The ductus arteriosus (DA) was assessed in the longitudinal plane of the fetus using color Doppler to confirm its course and flow direction, and pulsed Doppler sampling was placed at the proximal DA with an insonation angle <15°. Three consecutive measurements of PI were recorded and averaged. Z-scores were derived from predicted means and standard deviations and reference percentiles (5th, 50th, and 95th) were computed for gestational age groups using quantile regression. Intraobserver reproducibility was evaluated in 30 randomly selected cases with an interval ≥2 weeks using the intraclass correlation coefficient (ICC).Results: The mean gestational age was 28.2 ± 3.1 weeks. The ductal PI showed a mean of 2.4 ± 0.26 with normal distribution (p=0.2525). The Z-score equation for PI was successfully derived Z-score = (Measured PI - 2.4)/0.26. Reference ranges for PI were: 24-27 weeks (5th=2.0; 50th=2.4; 95th=2.7), 28-31 weeks (5th=2.1; 50th=2.5; 95th=2.9), and 32-34 weeks (5th=2.2; 50th=2.4; 95th=2.5). Intraobserver reproducibility for PI was excellent (ICC >0.90).Conclusions: We established gestational age-specific reference ranges and a Z-score equation for the ductal PI in normal fetuses between 24 and 33 + 6 weeks. These findings provide a standardized tool for fetal cardiologists to identify subtle ductal flow abnormalities and support perinatal risk stratification.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrapartum risk factors for neonatal intensive care unit admission in pregnancies with grade III meconium-stained amniotic fluid. III级羊水胎粪染色孕妇进入新生儿重症监护病房的产时危险因素。

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-04-21 DOI: 10.1515/jpm-2025-0322

Cen Cao, Haiyan Sun, Runrun Feng, Junling Fei, Min Zhang, Yihan Lu, Xinxin Zhu, Zhiping Ge, Ziyan Jiang

{"title":"Intrapartum risk factors for neonatal intensive care unit admission in pregnancies with grade III meconium-stained amniotic fluid.","authors":"Cen Cao, Haiyan Sun, Runrun Feng, Junling Fei, Min Zhang, Yihan Lu, Xinxin Zhu, Zhiping Ge, Ziyan Jiang","doi":"10.1515/jpm-2025-0322","DOIUrl":"https://doi.org/10.1515/jpm-2025-0322","url":null,"abstract":"Objectives: To analyze the high-risk factors of neonatal intensive care unit (NICU) admission in grade III meconium-stained amniotic fluid (MSAF) pregnancies and offer recommendations for clinical practice.Methods: Clinical data from 517 women with grade III MSAF during delivery were gathered for analysis. Two groups were examined using multivariable logistic regression in order to identify high-risk factors associated with NICU admission. The area under the receiver operating characteristic curve (ROC) was calculated to assess the relationship between NICU admission and blood tests during delivery.Results: The NICU admission group displayed a higher prevalence of thick meconium-stained amniotic fluid, a greater number of balloon catheter usage, worse routine blood test results during delivery, and higher 24 h vaginal bleeding volume, while lower rate of spontaneous membrane rupture. Logistic regression analysis identified abnormal fetal heart rate, maternal fever, and thick amniotic fluid as risk factors for NICU admission. Furthermore, ROC curve showed white blood cell (WBC) count and neutrophil percentage had a certain value of prediction for NICU admission.Conclusions: When grade III MSAF was found during delivery, if there is concurrent abnormal fetal heart monitoring, maternal fever and thick AF, a more cautious perinatal observation, a reasonable selection of delivery methods, and timely early resuscitation of newborns should be employed.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between oral glucose tolerance test (OGTT) glucose levels and fetal macrosomia in non-diabetic women. 非糖尿病妇女口服糖耐量试验（OGTT）血糖水平与胎儿巨大儿的关系

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-03-10 DOI: 10.1515/jpm-2025-0416

Taha Yasin Bayram, Reyhan Aslancan Bayram, Osman Murat Guler, Burak Yucel

{"title":"Association between oral glucose tolerance test (OGTT) glucose levels and fetal macrosomia in non-diabetic women.","authors":"Taha Yasin Bayram, Reyhan Aslancan Bayram, Osman Murat Guler, Burak Yucel","doi":"10.1515/jpm-2025-0416","DOIUrl":"https://doi.org/10.1515/jpm-2025-0416","url":null,"abstract":"Objectives: Foetal macrosomia is a significant obstetric problem that can lead to serious maternal/neonatal complications. The aim of this study was to determine which of the 75 g oral glucose tolerance test (OGTT) glucose values - fasting, first-hour, or second-hour - most strongly predicts foetal macrosomia in non-diabetic patients.Methods: This cross-sectional study prospectively screened 1,047 pregnant women who underwent a 75 g OGTT. Women with pregestational or gestational diabetes mellitus (GDM) were excluded from the main analysis. A total of 185 non-diabetic women were included. Among the included patients, those who delivered macrosomic foetuses constituted Group 1 (n=16), while those who delivered normal birth weight infants constituted Group 2 (n=169). Fasting, first-hour, and second-hour glucose values from the 75 g OGTT were compared between the groups.Results: No statistically significant differences were found between the two groups in terms of demographic variables (p>0.05). The mean fasting glucose values in Groups 1 and 2 were 77.75 and 76.11 mg/dL, respectively (p=0.42), the mean first-hour glucose values were 116.25 and 111.51 mg/dL, respectively (p=0.43), and the mean second-hour glucose values were 104.38 and 95.19 mg/dL, respectively (p=0.04). Receiver operating characteristic (ROC) curve analysis was performed for the second-hour glucose concentration, with an AUC of 0.675, and a threshold of 99.5 mg/dL was established.Conclusions: The second-hour glucose value of the 75 g OGTT may be a marker for foetal macrosomia in nondiabetic patients. These findings suggest that when the second-hour glucose value exceeds 99.5 mg/dL, foetal macrosomia may develop.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal and neonatal outcomes among pregnant women with eating disorders. 饮食失调孕妇的孕产妇和新生儿结局

IF 1.4 4区医学

Journal of Perinatal Medicine Pub Date : 2026-03-06 DOI: 10.1515/jpm-2025-0605

Asmaa El Mouden, Ethan Bendayan, Haim Arie Abenhaim

{"title":"Maternal and neonatal outcomes among pregnant women with eating disorders.","authors":"Asmaa El Mouden, Ethan Bendayan, Haim Arie Abenhaim","doi":"10.1515/jpm-2025-0605","DOIUrl":"https://doi.org/10.1515/jpm-2025-0605","url":null,"abstract":"Objectives: Eating disorders (ED), most prevalent among women of reproductive age, may negatively impact both maternal and fetal health during pregnancy. However, their effects remain inadequately explored. This study aimed to evaluate the associations between maternal ED and perinatal outcomes.Methods: A retrospective population-based cohort study of all delivery admissions from 2016 to 2021 was conducted using the United States' Healthcare Cost and Utilization Project-National Inpatient Sample. Pregnancies complicated by maternal ED were identified using ICD-10 codes F50.x. Associations between antenatal ED and adverse maternal and neonatal outcomes were assessed using multivariable logistic regression. Potential confounders adjusted for include baseline maternal demographics and relevant clinical factors.Results: Among 4,337,612 delivery admissions, 1,262 involved an ED diagnosis, with prevalence increasing from 23.9 to 37.6/100,000 (p<0.0001) over the study period. Patients with an ED were more likely to use tobacco, cannabis, and alcohol. Anxiety disorders, bipolar affective disorder, and depression were also more common among the ED group. Maternal ED was associated with higher risks of anemia (aOR 2.8, 95 % CI 2.6-3.3), preterm labor (1.4, 1.1-1.7), disseminated intravascular coagulation (6.2, 1.5-24.7), postpartum hemorrhage (1.9, 1.6-2.4), uterine rupture (4.4, 1.6-11.6), genitourinary tract infection (1.9, 1.1-3.3), and prolonged hospitalization (2.3, 1.7-3.1). Neonates of affected mothers were more likely to present with congenital anomalies (2.3, 1.6-3.4), IUGR (1.7, 1.4-2.1), fetal distress (1.3, 1.1-1.5), and preterm birth (1.4, 1.2-1.7).Conclusions: Pregnant individuals with ED constitute a high-risk group with elevated susceptibility to maternal and neonatal complications. Early recognition and integrated multidisciplinary care are crucial to improve outcomes.","PeriodicalId":16704,"journal":{"name":"Journal of Perinatal Medicine","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0