Journal of Parenteral and Enteral Nutrition最新文献

{"title":"Nutritional adequacy in critically ill adults receiving noninvasive ventilation: A descriptive cohort study","authors":"Francesca Deli MSc,&nbsp;Kevin Whelan PhD,&nbsp;Danielle E. Bear PhD","doi":"10.1002/jpen.2764","DOIUrl":"10.1002/jpen.2764","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Noninvasive ventilation (NIV) is increasingly being used in critical care, yet limited evidence exists guiding nutrition practices for patients who are critically ill receiving NIV. This study aimed to describe the nutrition practices and adequacy of nutrition intake among patients who are critically ill receiving NIV.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This descriptive cohort study included adult patients admitted to critical care who received NIV on ≥3 consecutive days. Prospectively recorded clinical data were retrospectively extracted from electronic medical records and compared between patients who received solely noninvasive ventilation (NIV only) and those who received invasive mechanical ventilation (IMV) and were extubated onto noninvasive ventilation (post-IMV group).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 220 patients included (107 NIV only; 113 post-IMV), 142 (64.5%) received exclusive oral nutrition, 66 (30.0%) received artificial nutrition support, and 12 (5.5%) received no nutrition. Enteral nutrition was more prevalent in the post-IMV group (36 [31.9%] vs NIV only 19 [17.8%]; <i>P</i> = 0.01), whereas exclusive oral nutrition was more prevalent in the NIV-only group (86 [80.4%] vs post-IMV 66 [58.4%]; <i>P</i> &lt; 0.001). Most patients who received purely exclusive oral nutrition (<i>n</i> = 152) had inadequate intake (94 [61.8%]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Most patients with critically illness receiving NIV received exclusive oral nutrition, which was found to be inadequate in the majority. Patients receiving NIV represent a nutritionally at-risk population, and future studies are needed to understand the barriers to oral intake and the feasibility, safety, and effectiveness of enteral nutrition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"609-618"},"PeriodicalIF":4.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2764","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in adverse events associated with different infusion modalities of parenteral nutrition: A pharmacovigilance study","authors":"Zhou Jing MPharm,&nbsp;Jiang Zhengli MPharm,&nbsp;Su Ying BD,&nbsp;Man Shiyu BD,&nbsp;Ma Jingjing MPharm,&nbsp;Pang Mujuan MPharm,&nbsp;Xu Hongyan MPharm,&nbsp;Hu Yan MPharm","doi":"10.1002/jpen.2763","DOIUrl":"10.1002/jpen.2763","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Parenteral nutrition can be administered through various infusion modalities. However, limited research has examined the differences in adverse reactions associated with these modalities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from the Food and Drug Administration adverse event reporting system database were analyzed using disproportionality analysis to identify and compare adverse event signals across different infusion modalities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1642 adverse event reports related to parenteral nutrition were included: 356 in the all-in-one group, 85 in the two-in-one group, 1086 in the fat emulsion group, and 115 in the amino acid supplementation group. Across all reports, 4159 preferred terms were identified, distributed as follows: 858 in the all-in-one group, 152 in the two-in-one group, 2975 in the fat emulsion group, and 174 in the amino acid supplementation group, with these events spanning 20 system organ classes. In the all-in-one group, the top three preferred terms were lymphangitis, increased blood magnesium, and incorrect drug administration rate. In the two-in-one group, the leading preferred terms were fungemia, extravasation, and disease complications. In the fat emulsion group, the most significant preferred terms included fat overload syndrome, fatty acid deficiency, and parenteral nutrition–associated liver disease. In the amino acid supplementation group, key preferred terms were impaired glucose tolerance, hyperglycemia, and elevated hepatic enzymes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study identified significant variations in the adverse events associated with different parenteral nutrition infusion modalities. These findings underscore the need for tailored interventions to ensure the safe and effective use of parenteral nutrition, thereby optimizing therapeutic outcomes in clinical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"659-669"},"PeriodicalIF":4.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence and unknowns for the relevancy of applying current parenteral nutrition support recommendations among infants born less than 750 g or younger than 25 weeks' gestation: A narrative review","authors":"Mar Romero-Lopez MD, PhD,&nbsp;Mamta Naik PharmD, RD, BCPPS,&nbsp;Teresa Hartman MLS,&nbsp;Ann Anderson-Berry MD, PhD,&nbsp;Melissa Thoene PhD, RD","doi":"10.1002/jpen.2761","DOIUrl":"10.1002/jpen.2761","url":null,"abstract":"<p>With advancements in neonatal care, the viability of extremely low-birth-weight (ELBW) infants, especially those born extremely preterm, is increasing. However, specific recommendations for managing parenteral nutrition (PN) support in nanopreterm infants (&lt;750 g or &lt;25 weeks' gestation) are lacking. We aim to evaluate current recommendations and highlight considerations for applying them to nanopreterm infants. The author team used English-language articles related to nutrition in ELBW with emphasis on nanopreterm infants, along with studies on fetal growth and metabolism. Current PN support recommendations for ELBW infants may not suit nanopreterm infants due to physiological and developmental differences. Key considerations for nanopreterm infants include:\u0000\u0000 </p><p>This review highlights the limitations of available PN support recommendations for nanopreterm infants. Further research is needed to establish precise guidelines that optimally meet their nutrition needs.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"560-571"},"PeriodicalIF":4.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2761","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLIM consensus approach to diagnosis of malnutrition: A 5-year update","authors":"Gordon L. Jensen MD, PhD,&nbsp;Tommy Cederholm MD, PhD,&nbsp;M. Isabel T. D. Correia MD, PhD,&nbsp;M. Cristina Gonzalez MD, PhD,&nbsp;Ryoji Fukushima MD, PhD,&nbsp;Veeradej Pisprasert MD, PhD,&nbsp;Renee Blaauw PhD, RD,&nbsp;Diana Cardenas Braz MD, PhD,&nbsp;Fernando Carrasco MD, MS,&nbsp;Alfonso J. Cruz Jentoft MD, PhD,&nbsp;Cristina Cuerda MD, PhD,&nbsp;David C. Evans MD,&nbsp;Vanessa Fuchs-Tarlovsky PhD, MD,&nbsp;Leah Gramlich MD,&nbsp;Han Ping Shi MD, PhD,&nbsp;Jeanette M. Hasse PhD, RD,&nbsp;Michael Hiesmayr MD,&nbsp;Naoki Hiki MD, PhD,&nbsp;Harriët Jager-Wittenaar PhD, RD,&nbsp;Shukri Jahit MD,&nbsp;Anayanet Jáquez MD,&nbsp;Heather Keller PhD, RD,&nbsp;Stanislaw Klek MD, PhD,&nbsp;Ainsley Malone MS, RD,&nbsp;Kris M. Mogensen MS, RD-AP,&nbsp;Naoharu Mori MD, PhD,&nbsp;Manpreet Mundi MD,&nbsp;Maurizio Muscaritoli MD,&nbsp;Doris Ng MRCP, DPhil,&nbsp;Ibolya Nyulasi MSc, APD,&nbsp;Matthias Pirlich MD, PhD,&nbsp;Stephane Schneider MD, PhD,&nbsp;Marian de van der Schueren PhD, RD,&nbsp;Soranit Siltharm MD,&nbsp;Pierre Singer MD,&nbsp;Alison Steiber PhD, RDN,&nbsp;Kelly A. Tappenden PhD, RD,&nbsp;Jianchun Yu MD, PhD,&nbsp;André van Gossum MD, PhD,&nbsp;Jaw-Yuan Wang MD, PhD,&nbsp;Marion F. Winkler PhD, RD,&nbsp;Charlene Compher PhD, RD,&nbsp;Rocco Barazzoni MD, PhD","doi":"10.1002/jpen.2756","DOIUrl":"10.1002/jpen.2756","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The Global Leadership Initiative on Malnutrition (GLIM) introduced an approach for malnutrition diagnosis in 2019 that comprised screening followed by assessment of three phenotypic criteria (weight loss, low body mass index [BMI], and low muscle mass) and two etiologic criteria (reduced food intake/assimilation and inflammation/disease burden). This planned update reconsiders the GLIM framework based on published knowledge and experience over the past 5 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A working group (<i>n</i> = 43 members) conducted a literature search spanning 2019–2024 using the keywords “Global Leadership Initiative on Malnutrition or GLIM.” Prior GLIM guidance activities for using the criteria on muscle mass and inflammation were reviewed. Successive rounds of revision and review were used to achieve consensus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>More than 400 scientific reports were published in peer-reviewed journals, forming the basis of 10 systematic reviews, some including meta-analyses of GLIM validity that indicate strong construct and predictive validity. Limitations and future priorities are discussed. Working group findings suggest that assessment of low muscle mass should be guided by experience and available technological resources. Clinical judgment may suffice to evaluate the inflammation/disease burden etiologic criterion. No revisions of the weight loss, low BMI, or reduced food intake/assimilation criteria are suggested. After two rounds of review and revision, the working group secured 100% agreement with the conclusions reported in the 5-year update.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ongoing initiatives target priorities that include malnutrition risk screening procedures, GLIM adaptation to the intensive care setting, assessment in support of the reduced food intake/assimilation criterion, and determination of malnutrition in obesity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"414-427"},"PeriodicalIF":4.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2756","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143908921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to “Parenteral nutrition and bioelectrical impedance analysis estimated fat-free mass in adult patients with chronic intestinal failure: A descriptive cohort study”","authors":"Julia W. Korzilius MD,&nbsp;Manon Dumont MSc,&nbsp;Harriët Jager-Wittenaar PhD,&nbsp;Geert J. A. Wanten PhD,&nbsp;Heidi E. E. Zweers- van Essen PhD","doi":"10.1002/jpen.2762","DOIUrl":"10.1002/jpen.2762","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of protein and amino acids supplements on muscle strength and physical performance: A scoping review of randomized controlled trials","authors":"Alaa H. Al-Rawhani MSc,&nbsp;Siti Nur'Asyura Adznam PhD,&nbsp;Zalina Abu Zaid PhD,&nbsp;Nor Baizura Md. Yusop PhD,&nbsp;Hakimah M. Sallehuddin PhD,&nbsp;Mohammed A. Alshawsh PhD","doi":"10.1002/jpen.2749","DOIUrl":"10.1002/jpen.2749","url":null,"abstract":"<p>Protein and amino acid supplementation is an effective intervention that significantly enhances physical function and reduces frailty and sarcopenia in older adults. This scoping review aims to map and synthesize the available evidence on the effects of various types of protein and amino acid supplementation in this population. Following the PRISMA-ScR guidelines, we conducted a literature search to identify clinical trials examining the effects of protein and amino acid supplementation, with or without physical exercise, on muscle strength, physical performance, and body composition in healthy, frail, or sarcopenic older adults. Our analysis of 80 trials with a total of 5290 participants examines the evidence for the effectiveness of protein supplementation in enhancing muscle strength and body composition. Whey protein, creatine, milk protein, leucine, essential amino acids, and soy protein were the most used types of protein, and our findings indicate that whey protein, creatine, and milk protein yield the best results when used in conjunction with resistance training. Additionally, leucine and milk protein have shown the potential to enhance body composition even without concurrent resistance training. In conclusion, studies on the effectiveness of whey protein in improving muscle strength and body composition in older adults with resistance training are inconsistent. More research is required to explore the potential benefits of soy and leucine-enriched supplements. Protein supplementation's impact on physical performance remains inconclusive. Further studies are needed to determine the effects of protein types and supplementation on muscle-related parameters in older adults.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"548-559"},"PeriodicalIF":4.1,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between GLIM diagnosed malnutrition and 18-month mortality in hospitalized adults with congestive heart failure: A prospective cohort study","authors":"Ruoshu Duan MD, PhD,&nbsp;Suxiu Chen MM,&nbsp;Suxia Li MM,&nbsp;Jie Ding MD,&nbsp;Lei Wang MD, PhD,&nbsp;Yangli Li MM,&nbsp;Jingjing Ren MD,&nbsp;Sujing Jiang MD","doi":"10.1002/jpen.2760","DOIUrl":"10.1002/jpen.2760","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The Global Leadership Initiative on Malnutrition (GLIM) criteria have been validated in various clinical settings since 2018, but prospective validation in patients with congestive heart failure (CHF) who are hospitalized remains limited. This study compares the prognostic performance of the GLIM criteria and Mini-Nutritional Assessment (MNA)-defined malnutrition for all-cause mortality in CHF patients and explores the strongest predictive indicator within the GLIM criteria.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This single-center prospective cohort study included inpatients with CHF. Agreement between the GLIM criteria and MNA was assessed using Cohen <i>κ</i> coefficient. Survival data were analyzed using Kaplan-Meier curves and adjusted Cox regression analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 498 CHF inpatients, 84 (16.9%) died during the 18-month follow-up. Malnutrition prevalence was 47.2% and 50.4% based on the GLIM criteria and MNA, respectively (<i>κ</i> = 0.68; <i>P</i> &lt; 0.001). Malnutrition was independently associated with a higher risk of all-cause mortality (GLIM criteria: hazard ratio, 2.16 [95% confidence interval (CI), 1.13–4.13]; MNA: hazard ratio, 4.28 [95% CI, 1.98–9.22]). Low body mass index was the strongest predictor of all-cause mortality in multivariable analysis (hazard ratio, 5.14; 95% CI, 3.19–8.27).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The GLIM criteria showed strong consistency with MNA and effectively predicted all-cause mortality in CHF patients within 18 months.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"633-642"},"PeriodicalIF":4.1,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between enteral nutrition initiation within 48 h of intubation and 90-day mortality in patients with severe acute heart failure requiring mechanical circulatory support: A retrospective cohort study","authors":"Takeshi Saijo RD, PhD,&nbsp;Koji Yasumoto MD,&nbsp;Kayoko Ryomoto MD, PhD,&nbsp;Chika Momoki RD, PhD,&nbsp;Daiki Habu MD, PhD","doi":"10.1002/jpen.2759","DOIUrl":"10.1002/jpen.2759","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>We explored the association between the initiation of enteral nutrition within 48 h of intubation and 90-day mortality in patients with severe acute heart failure requiring mechanical circulatory support.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed patients with acute heart failure who were admitted to the critical care unit and underwent endotracheal intubation and mechanical circulatory support. Multivariate Cox proportional hazard models were used to evaluate the association between early enteral nutrition and 90-day mortality. Multivariate logistic regression analyses were used to evaluate the association between early enteral nutrition and the incidence of infectious- and enteral nutrition-related complications. The following variables were used in the analysis: sequential organ failure assessment, lactate, length of mechanical circulatory support, early enteral nutrition, body mass index, chronic renal failure, serum albumin level, cardiopulmonary arrest, diabetes mellitus, intraaortic balloon pump, venoarterial extracorporeal membrane oxygenation, and IMPELLA. These variables were then examined in models with different combinations for outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The analysis included 80 and 35 patients in the early and delayed enteral nutrition groups, respectively. Multivariate analysis indicated that early enteral nutrition was an independent factor for reduced 90-day mortality (model 1: hazard ratio = 0.39 [95% confidence interval = 0.19–0.77]; model 2: hazard ratio = 0.38 [95% confidence interval = 0.19–0.76]; model 3: hazard ratio = 0.41 [95% confidence interval = 0.20–0.81]; and model 4: hazard ratio = 0.38 [95% confidence interval = 0.19–0.76]). Furthermore, early enteral nutrition was an independent factor for infectious complications but not for enteral nutrition-related complications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Early enteral nutrition can be initiated without increasing complications in patients with severe acute heart failure requiring mechanical circulatory support. This may have beneficial effect on improving prognosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"619-632"},"PeriodicalIF":4.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transition readiness assessment in adolescents and young adults with chronic intestinal failure on home parenteral nutrition: A descriptive cross-sectional study","authors":"Aysenur Demirok MD,&nbsp;Marc A. Benninga MD, PhD,&nbsp;Antonella Diamanti MD, PhD,&nbsp;Myriam El Khatib MD, PhD,&nbsp;Anat Guz-Mark MD,&nbsp;Johannes Hilberath MD,&nbsp;Cécile Lambe MD,&nbsp;Lorenzo Norsa MD, PhD,&nbsp;Anna Simona Sasdelli MD, PhD,&nbsp;Alida A. Sanchez MD,&nbsp;Mireille Serlie MD, PhD,&nbsp;Merit M. Tabbers MD, PhD","doi":"10.1002/jpen.2747","DOIUrl":"10.1002/jpen.2747","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Life expectancy for patients with chronic intestinal failure (CIF) recieving home parenteral nutrition (HPN) has improved over the past decades. Consequently, more children on HPN grow into adulthood. Until now, no assessment of transition readiness of these patients exists. Aim is to assess readiness of adolescents recieving HPN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is an international, prospective, cross-sectional multicenter study in collaboration with members of the Intestinal Failure working group—European Reference Network for Rare Inherited and Congenital (Digestive and Gastrointestinal) Anomalies and the Network of Intestinal Failure and Intestinal Transplant in Europe—European Society for Pediatric Gastroenterology Hepatology and Nutrition conducted between April and November 2023. A validated Transition Readiness Assessment Questionnaire was used to measure patient- and parent-reported transition readiness in adolescents on HPN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 57 participants aged 16 to 24 years were included across eight countries. Patient-reported outcomes show a lack of readiness for transition among the total cohort with 65% scoring below the threshold. Younger patients (aged 16–18 years), male patients, and those in pediatric settings reported significant lower readiness. Parent-reported scores were higher compared with the patient-reported outcomes, reaching the threshold for transition readiness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The transition readiness of adolescents with CIF receiving HPN presents is proven to be low. This study underscores the necessity for the use of a standardized transition protocol. Emphasizing the importance of successful transition in this vulnerable patient group will enhance the outcomes and independence of adolescents during their transition into the adult healthcare system.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 5","pages":"599-608"},"PeriodicalIF":4.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2747","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of dietitians in optimizing medical nutrition therapy in cardiac surgery patients: A secondary analysis of an international multicenter observational study","authors":"Ellen Dresen PhD,&nbsp;Danielle E. Bear PhD,&nbsp;Ashley DePriest RD,&nbsp;Ranna Modir MS, RD,&nbsp;Omy Naidoo RD,&nbsp;Charlene Compher RD, PhD,&nbsp;Andrea Ho RD,&nbsp;Pui Hing Foong MSc,&nbsp;Maria Eloisa Garcia Velásquez MD,&nbsp;Zheng-Yii Lee PhD,&nbsp;Charles Chin Han Lew APD, PhD,&nbsp;Gunnar Elke MD,&nbsp;Jayshil J. Patel MD,&nbsp;Liam McKeever RDN, PhD,&nbsp;Katharina Berschauer MD,&nbsp;Catarina Rosa Domingues RD, BSc,&nbsp;Juan Carlos Lopez-Delgado MD, PhD,&nbsp;Patrick Meybohm MD,&nbsp;Daren K. Heyland MD, MSc,&nbsp;Christian Stoppe MD","doi":"10.1002/jpen.2755","DOIUrl":"10.1002/jpen.2755","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Better understanding the impact of dietetic services on nutrition practices seems required as it may represent an opportunity for optimization in post–cardiac surgery patients. The present study aims to evaluate and compare nutrition practices and clinical outcomes in post–cardiac surgery intensive care unit (ICU) patients with and without dietetic services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is a secondary analysis of a multinational prospective observational study in patients (<i>n</i> = 237) with &gt;72 h of post–cardiac surgical ICU stay with and without dietetic services describing nutrition practices and outcomes up to 12 days after ICU admission.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Dietetic services were available in 61.5% (8 of 13) ICUs (1.0 ± 0.5 full-time equivalents/10 beds). Enteral nutrition was initiated &lt;48 h from ICU admission in 49.6% and 59.1% of patients at sites with vs without dietetic services, respectively. Parenteral nutrition was started within 118.3 ± 56.5 and 131.5 ± 69.2 h at sites with vs without dietetic services, respectively. Energy target (23.7 ± 4.8 vs 24.6 ± 4.8 kcal/kg body weight/day) and actual supply (10.5 ± 6.7 vs 10.3 ± 6.2 kcal/kg body weight/day) did not differ between the groups. Protein targets (1.4 ± 0.4 vs 1.1 ± 1.3 g/kg body weight/day) and actual protein provision (0.6 ± 0.4 vs 0.4 ± 0.3 g/kg body weight/day) were higher in patients at sites with vs without dietetic services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Improvements in medical nutrition therapy practices in patients after cardiac surgery are needed in ICUs with and without dietetic services. Appropriately staffed dietetic services as essential members of the medical care team may be crucial to transfer knowledge on adequate medical nutrition therapy strategies into practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"476-487"},"PeriodicalIF":4.1,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2755","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}