Journal of oral science最新文献_第9页

Citral-rich fractions of Lippia alba essential oils as immunoresponsive and anti-Candida albicans additives for collagen membranes in guided bone regeneration. 富含柠檬醛成分的白皮精油作为免疫反应和抗白色念珠菌添加剂用于引导骨再生的胶原膜。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0058

Nohora C Rugeles-Páez, Wendy L Quintero, Elena E Stashenko, Liliana T García

{"title":"Citral-rich fractions of Lippia alba essential oils as immunoresponsive and anti-Candida albicans additives for collagen membranes in guided bone regeneration.","authors":"Nohora C Rugeles-Páez, Wendy L Quintero, Elena E Stashenko, Liliana T García","doi":"10.2334/josnusd.23-0058","DOIUrl":"https://doi.org/10.2334/josnusd.23-0058","url":null,"abstract":"Purpose: The aim of this study was to optimize the immunoresponsive and anti-Candida albicans (C. albicans) properties of guided bone regeneration-resorbable membranes (collagen) using additives based on synergistic mixtures of chlorhexidine with terpene-enriched fractions from Lippia alba essential oils (EO).Methods: The anti-C. albicans activity of the fractions (individually or combined with chlorhexidine) was evaluated using planktonic and sessile cultures. J774A.1 murine macrophage cells were used to determine the cytotoxicity and immunoresponsive effects of the therapies.Results: The anti-planktonic and anti-sessile performance of chlorhexidine on C. albicans was improved 2- to 4-fold by supplementation with citral-rich fractions. On macrophages, this fraction also exhibited a potentially cytoprotective action against the toxic effects of chlorhexidine, minimizing damage to the cell membrane, mitochondrial membrane potential, and nuclear integrity. Macrophages growing on collagen-membrane fragments and stimulated with the citral fraction (alone or with chlorhexidine) showed a significant increase in releasing the osteogenic cytokine TNF-α and enhancing the IL-4.Conclusion: This combined therapy appears as a promising platform for the development of a prophylactic or therapeutic biocidal solution that can optimize the pharmacological characteristics of chlorhexidine (epithelium tolerance and anti-C. albicans consolidation on surfaces), as well as potentiating the immunoresponsive properties of collagen membranes.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"176-183"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9745486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concentration-dependent effect of carboxymethyl chitosan amorphous calcium phosphate on the surface hardness of primary tooth enamel. 羧甲基壳聚糖无定形磷酸钙对原牙釉质表面硬度的浓度依赖性研究。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0084

Theodora Elien, Heriandi Sutadi, Margaretha Suharsini

引用次数: 0

Occlusion of dentinal tubules on periodontally involved teeth by dentifrice containing stannous fluoride and sodium fluoride. 含氟化亚锡和氟化钠的牙膏阻塞牙周病牙齿的牙本质小管。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.22-0486

Çiğdem Doğan, Hatice S Yıldırım, Hare Gürsoy, Leyla Kuru

{"title":"Occlusion of dentinal tubules on periodontally involved teeth by dentifrice containing stannous fluoride and sodium fluoride.","authors":"Çiğdem Doğan, Hatice S Yıldırım, Hare Gürsoy, Leyla Kuru","doi":"10.2334/josnusd.22-0486","DOIUrl":"https://doi.org/10.2334/josnusd.22-0486","url":null,"abstract":"Purpose: This study examined the occlusion effect of a dentifrice containing stannous fluoride (SnF2) and sodium fluoride (NaF) on periodontally involved teeth in comparison with healthy teeth using scanning electron microscopy (SEM) in comparison with a dentifrice containing NaF alone.Methods: Sixty dentine samples obtained from single-rooted premolars, 15 of them extracted for orthodontic reasons (Group H) and 15 because of periodontal destruction (Group P), were included in the study. Each group of specimens was further divided into subgroups: HC and PC (control), H1 and P1 (treated with SnF2 and NaF), and H2 and P2 (treated with NaF). The samples were brushed twice a day for 7 days, kept in artificial saliva, and examined by SEM. The diameters of open tubules and the numbers of tubules were assessed at ×2,000 magnification.Results: The H and P groups showed similar diameters of open tubules. The numbers of open tubules in Groups H1, P1, H2, and P2 were significantly lower than in Groups HC and PC (P < 0.001), and consistent with the percentages of occluded tubules. Group P1 had the highest percentage of occluded tubules.Conclusions: Although both dentifrices were found to successfully occlude dentinal tubules, the dentifrice containing SnF2 and NaF provided the highest degree of occlusion in periodontally involved teeth.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"149-152"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9742547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of tetrabutylammonium dihydrogen trifluoride etchant on bond strengths of resin composites with Ti-6Al-4V and Co-Cr alloys. 四丁基三氟化二氢铵蚀刻剂对Ti-6Al-4V和Co-Cr合金树脂复合材料结合强度的影响

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0010

Kohji Kamada, Yohsuke Taira, Takafumi Egoshi, Kei Kaida

{"title":"Effects of tetrabutylammonium dihydrogen trifluoride etchant on bond strengths of resin composites with Ti-6Al-4V and Co-Cr alloys.","authors":"Kohji Kamada, Yohsuke Taira, Takafumi Egoshi, Kei Kaida","doi":"10.2334/josnusd.23-0010","DOIUrl":"https://doi.org/10.2334/josnusd.23-0010","url":null,"abstract":"Purpose: This study aimed at evaluating the effects of surface treatments with tetrabutylammonium dihydrogen trifluoride (TDTF) on the bond strengths of indirect resin composites with titanium-aluminum-vanadium (Ti-6Al-4V) and cobalt-chromium (Co-Cr) alloys.Methods: Disk-shaped Ti-6Al-4V and Co-Cr alloy specimens were air-abraded with alumina, treated with an etchant (MEP) containing TDTF for 10 s (MEP10) or 30 s (MEP30), and rinsed with water. Subsequently, a primer containing 6-methacryloyloxyhexyl phosphonoacetate was applied to the surfaces, and the specimens were veneered with a light-curing indirect resin composite. Specimens without MEP were prepared as controls (no-MEP). Shear bond strengths were determined before or after 100,000 thermocycles, and the data were analyzed using the Steel-Dwass test (α = 0.05, n = 10).Results: No significant difference was found in the bond strengths between the Ti-6Al-4V and Co-Cr alloys. In each metal alloy, the MEP10 and MEP30 specimens exhibited higher bond strengths than the no-MEP controls after 100,000 thermocycles. Scanning electron microscopy observations revealed that submicron-pits and crevices were formed on both the metal alloys upon applying the MEP etchant.Conclusion: Surface treatments with TDTF following air abrasion are useful for improving bonding durability while veneering resin composites on Ti-6Al-4V or Co-Cr alloy frameworks.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"153-157"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9745485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A nested case-control study of factors contributing to the development of medication-related osteonecrosis of the jaw in patients using bone resorption inhibitors in Mishima City. 三岛市使用骨吸收抑制剂的患者发生药物相关性颌骨骨坏死相关因素的巢式病例对照研究。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0096

Keisuke Seki, Atsushi Kamimoto, Maki Wada, Toshimitsu Iinuma

{"title":"A nested case-control study of factors contributing to the development of medication-related osteonecrosis of the jaw in patients using bone resorption inhibitors in Mishima City.","authors":"Keisuke Seki, Atsushi Kamimoto, Maki Wada, Toshimitsu Iinuma","doi":"10.2334/josnusd.23-0096","DOIUrl":"https://doi.org/10.2334/josnusd.23-0096","url":null,"abstract":"Purpose: Medication-related osteonecrosis of the jaw (MRONJ) is characterized by necrosis of the jawbone with intraoral bacterial infection and has a significant negative impact on oral health-related quality of life. Risk factors for the onset are unknown, and definitive therapeutic approaches have not yet been defined. A case-control study at a single institution in Mishima City was conducted. The purpose of this study was to examine in detail the factors that contribute to the development of MRONJ.Methods: Medical records of MRONJ patients who visited Mishima Dental Center, Nihon University School of Dentistry, during the period 2015-2021 were extracted. Counter-matched sampling design was used to select participants matched for sex, age, and smoking for this nested case-control study. The incidence factors were statistically examined by logistic regression analysis.Results: Twelve MRONJ patients were used as cases and 32 controls were matched. After adjustment for potential confounders, injectable bisphosphonates (aOR = 24.5; 95% CI = 1.05, 575.0; P < 0.05) were significantly associated with the development of MRONJ.Conclusion: High-dose bisphosphonates may be a risk factor for the development of MRONJ. Patients who use these products require careful prophylactic dental treatment against inflammatory diseases, and dentists and physicians should maintain close communication.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"184-189"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9745479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Clinical performance of two onlay designs for molars after root canal treatment. 牙根管治疗后两种牙体的临床表现。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.22-0450

Shujiang Chen, Meng Lu, Zhimin Zhu, Wenchuan Chen

{"title":"Clinical performance of two onlay designs for molars after root canal treatment.","authors":"Shujiang Chen, Meng Lu, Zhimin Zhu, Wenchuan Chen","doi":"10.2334/josnusd.22-0450","DOIUrl":"https://doi.org/10.2334/josnusd.22-0450","url":null,"abstract":"Purpose: To evaluate the clinical performance of two proposed onlay designs.Methods: Molars with occlusal and/or mesial/distal defects after root canal treatment were classified by design into three groups. Onlays without shoulders were the control group (Group C, n = 50). The designed onlays were Group O (n = 50) and the designed mesio-occlusal/disto-occlusal onlays were Group MO/DO (n = 80). All onlays had an occlusal thickness of approximately 1.5-2.0 mm, and the designed onlays had a shoulder depth and width of approximately 1 mm. In Groups C and O, the box-shaped retention was 1.5 mm in depth. The proximal box was connected with a dovetail retention in Group MO/DO. Patients were examined every 6 months and followed for 36 months. Restorations were evaluated by using the modified United States Public Health Service Criteria. Statistical analysis was performed by using Kaplan-Meier analysis, the chi-square test, and Fisher's exact test.Results: No tooth fracture, debonding, secondary caries, or gingivitis was observed in any group. Groups O and MO/DO had satisfactory survival and success rates, and there was no significant difference in performance characteristics among the three groups (P > 0.05).Conclusion: The two proposed onlay designs were effective in protecting molars.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"171-175"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9745481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined effect of apigenin and reduced graphene oxide against Enterococcus faecalis biofilms. 芹菜素和还原氧化石墨烯对粪肠球菌生物膜的联合作用。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.22-0459

Mi-Ah Kim, Kyung-San Min

{"title":"Combined effect of apigenin and reduced graphene oxide against Enterococcus faecalis biofilms.","authors":"Mi-Ah Kim, Kyung-San Min","doi":"10.2334/josnusd.22-0459","DOIUrl":"https://doi.org/10.2334/josnusd.22-0459","url":null,"abstract":"Purpose: Enterococcus faecalis (E. faecalis) is one of the major microorganisms that causes failure of endodontic treatment. This study aimed to investigate the antibacterial activity of apigenin and its synergistic effect with reduced graphene oxide (RGO) in treating E. faecalis biofilms.Methods: The antibacterial activities were characterized by viability analysis including colony forming units and confocal laser scanning microscopy (CLSM) analyses. The effect on biofilm biomass was measured using a crystal violet staining method. Live and dead bacteria bio-volumes were determined by CLSM analysis, and the morphology of E. faecalis biofilm after treatment with apigenin and apigenin + RGO was observed by scanning electron microscopy (SEM).Results: The viability of E. faecalis in biofilms decreased by apigenin treatment in a dose-dependent manner. While apigenin alone did not significantly affect the biofilm biomass, apigenin + RGO reduced the biomass in an apigenin concentration-dependent manner. Likewise, the bio-volume of live bacteria decreased and the bio-volume of dead bacteria increased in apigenin-treated biofilms. According to SEM images, apigenin + RGO-treated samples showed less E. faecalis in biofilms than apigenin-only treated samples.Conclusion: The results suggested that the combined use of apigenin and RGO could be a potential strategy for effective endodontic disinfection.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"163-167"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10119139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity of analysis of masticatory movement using a two-dimensional mandibular movement recording device. 使用二维下颌运动记录装置分析咀嚼运动的有效性。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0060

Masaoki Yokoyama, Hiroshi Shiga, Marie Komino, Hanako Uesugi, Mako Sano, Tohru Naitoh

引用次数: 0

Evaluation of machine-assisted irrigation on removal of intracanal biofilm and extrusion of sodium hypochlorite using a three-dimensionally printed root canal model. 利用三维打印根管模型评价机器辅助灌洗去除根管内生物膜和挤出次氯酸钠的效果。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-07-01 DOI: 10.2334/josnusd.23-0025

Ji-Yoon Shin, Mi-Ah Kim, Hee-Jin Kim, Prasanna Neelakantan, Mi-Kyung Yu, Kyung-San Min

{"title":"Evaluation of machine-assisted irrigation on removal of intracanal biofilm and extrusion of sodium hypochlorite using a three-dimensionally printed root canal model.","authors":"Ji-Yoon Shin, Mi-Ah Kim, Hee-Jin Kim, Prasanna Neelakantan, Mi-Kyung Yu, Kyung-San Min","doi":"10.2334/josnusd.23-0025","DOIUrl":"https://doi.org/10.2334/josnusd.23-0025","url":null,"abstract":"Purpose: This study aimed to compare the biofilm removal and apical extrusion of sodium hypochlorite (NaOCl) following machine-assisted irrigation using a three-dimensionally (3D) printed dentin-insert model.Methods: Multispecies biofilms were formed in a 3D-printed curved root canal model with dentin insert. The model was then placed in a container that was filled with 0.2% agarose gel containing 0.1% m-Cresol purple. Root canals were irrigated with 1% NaOCl using syringe irrigation, sonically agitated (EndoActivator or EDDY) or ultrasonically activated (Endosonic Blue) irrigation. Samples were photographed and the color-changed area was measured. Biofilm removal was assessed using colony-forming unit counting, confocal laser scanning microscopic analysis and scanning electron microscopic observations. The data were analyzed using one-way ANOVA, followed by Tukey test (P < 0.05).Results: EDDY and Endosonic Blue demonstrated significantly greater reduction of biofilms compared to other groups. No significant differences were observed in the remaining biofilm volume in syringe irrigation and EndoActivator groups. Furthermore, EDDY and Endosonic Blue presented with numerous exposed dentinal tubules. EDDY showed significantly greater NaOCl extrusion compared to other groups.Conclusion: Ultrasonic activation with a small-sized nickel-titanium file irrigation system may be beneficial in intracanal biofilm removal avoiding extrusion of NaOCl beyond the root apex.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 3","pages":"158-162"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9745462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin facilitates synaptic transmission via gap junctions between fast-spiking interneurons in the rat insular cortex. 胰岛素通过大鼠岛叶皮层中快速脉冲中间神经元之间的间隙连接促进突触传递。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-03-30 DOI: 10.2334/josnusd.22-0438

Satoshi Kosukegawa, Yuka Nakaya, Satomi Kobayashi, Kohei Kitano, Sachie Matsumura, Shohei Ogisawa, Manabu Zama, Mitsuru Motoyoshi, Masayuki Kobayashi

{"title":"Insulin facilitates synaptic transmission via gap junctions between fast-spiking interneurons in the rat insular cortex.","authors":"Satoshi Kosukegawa, Yuka Nakaya, Satomi Kobayashi, Kohei Kitano, Sachie Matsumura, Shohei Ogisawa, Manabu Zama, Mitsuru Motoyoshi, Masayuki Kobayashi","doi":"10.2334/josnusd.22-0438","DOIUrl":"https://doi.org/10.2334/josnusd.22-0438","url":null,"abstract":"Purpose: Inhibitory synaptic currents from fast-spiking neurons (FSNs), a typical gamma-aminobutyric acid (GABA)ergic interneuron in the cerebral cortex, to pyramidal neurons are facilitated by insulin. FSNs frequently show electrical synapses to FSNs, however, the effect of insulin on these electrical synapses is unknown. The aim of this study was to evaluate effects of insulin on electrical synaptic potentials between FSNs.Methods: Electrical synaptic potentials via gap junctions between FSNs were recorded to examine how insulin modulates these potentials in the rat insular cortex (IC).Results: Bath application of insulin (10 nM), which increases the spike firing rate of pyramidal neurons and unitary inhibitory postsynaptic currents recorded from FSN to pyramidal neuron connections, slightly but significantly increased electrical synaptic currents. The mean ratio of electrical synapses, the coupling coefficient that is obtained by postsynaptic voltage responses divided by presynaptic voltage amplitude, was 8.3 ± 1.1% in control and 9.2 ± 1.1% (n = 14) during 10 nM insulin application. Input resistance and voltage responses to large hyperpolarizing currents (-140 pA) were not changed by insulin.Conclusion: These results suggest that insulin facilitates spike synchronization by increasing electrical synaptic currents via gap junctions of GABAergic FSNs in the IC.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"65 2","pages":"77-80"},"PeriodicalIF":1.9,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9209760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0