Journal of oral science最新文献_第9页

A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel. 两种化学模型对柱状牙釉质和柱状牙釉质表面下龋形成的比较研究。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0311

Pamela Y W Wong, Suh Ling Lim, Samuel T Y Loi, May Lei Mei, Kai Chun Li, Shafiq Aziz, Manikandan Ekambaram

{"title":"A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.","authors":"Pamela Y W Wong, Suh Ling Lim, Samuel T Y Loi, May Lei Mei, Kai Chun Li, Shafiq Aziz, Manikandan Ekambaram","doi":"10.2334/josnusd.22-0311","DOIUrl":"https://doi.org/10.2334/josnusd.22-0311","url":null,"abstract":"Purpose: To investigate the mineral density and lesion depth of artificial caries lesions on aprismatic enamel and prismatic enamel created by lactic acid and acetic acid buffers.Methods: Forty bovine enamel blocks were allocated to: aprismatic enamel (Group A) and prismatic enamel (Group C) in acetic acid buffer for 192 h and aprismatic enamel (Group B) and prismatic enamel (Group D) in lactic acid buffer for 96 h. The mineral loss and lesion depth were measured using micro-computed tomography.Results: A significant difference (P = 0.01) was observed in the mineral loss (%) in the lesions on aprismatic enamel and prismatic enamel treated with lactic acid buffer while no significant difference (P = 0.51) was observed in the mineral loss (%) in the lesions on aprismatic enamel and prismatic enamel treated with acetic acid buffer. No significant difference was noted in the mean lesion depth of lesions on aprismatic enamel and prismatic enamel treated with acetic acid and lactic acid buffers (P > 0.05).Conclusion: Aprismatic enamel and prismatic enamel have similar mineral loss in acetic acid while prismatic enamel showed more mineral loss compared to aprismatic enamel in lactic acid.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10522809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Association of self-rated chewing function and oral health status with metabolic syndrome. 自评咀嚼功能和口腔健康状况与代谢综合征的关系。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0229

Mizuki Saito, Yoshihiro Shimazaki, Saori Yoshii, Hideo Takeyama

{"title":"Association of self-rated chewing function and oral health status with metabolic syndrome.","authors":"Mizuki Saito, Yoshihiro Shimazaki, Saori Yoshii, Hideo Takeyama","doi":"10.2334/josnusd.22-0229","DOIUrl":"https://doi.org/10.2334/josnusd.22-0229","url":null,"abstract":"Purpose: The study aimed to examine the association of self-rated chewing function, the number of teeth and periodontal status with metabolic syndrome.Methods: The participants were 11,119 adults aged 40-74 years who underwent specific health checkups, including an oral health examination, in 2018 in Japan. This study used the standard questions of the specific health checkups to obtain information on self-rated chewing function. A multinomial logistic regression analysis was performed with metabolic syndrome status as the dependent variable, and age, sex, lifestyle questions, self-rated chewing function, number of teeth, and periodontal status as the independent variables.Results: Number of teeth and periodontal status were significantly associated with metabolic syndrome after adjusting for confounding variables. Self-rated chewing function was significantly associated with metabolic syndrome in the crude analysis, but not after adjustment for confounding variables. Both number of teeth and periodontal status were significantly associated with self-rated chewing function.Conclusion: There was no significant direct association between self-rated chewing function and metabolic syndrome. Self-rated chewing function may be an indicator of poor oral condition that links to metabolic syndrome.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10594236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Custom-made radiotherapy prosthesis for external and internal radiotherapy in a patient with lip cancer. 定制放疗假体用于唇部癌患者的外、内放疗。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0306

Jiangyu Wang, Mai Murase, Cheewin Towithelertkul, Hiroko Tani, Yuka I Sumita

引用次数: 0

Cell viability and physicochemical effects of different concentrations of bismuth trioxide in a mineral trioxide aggregate cement. 不同浓度的三氧化二铋在矿物三氧化二骨料水泥中的细胞活力和物理化学效应。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0139

Karla Padrón-Alvarado, Laura A García-Mendoza, Juana P Ramírez-Ortega, Jacqueline A Rodríguez-Chavéz, María D L A Moyaho-Bernal, Juan A Arreguín-Cano, Lia A Hoz-Rodríguez, Ana Wintergerst, Jesús A Arenas-Alatorre, Abigailt Flores-Ledesma

{"title":"Cell viability and physicochemical effects of different concentrations of bismuth trioxide in a mineral trioxide aggregate cement.","authors":"Karla Padrón-Alvarado, Laura A García-Mendoza, Juana P Ramírez-Ortega, Jacqueline A Rodríguez-Chavéz, María D L A Moyaho-Bernal, Juan A Arreguín-Cano, Lia A Hoz-Rodríguez, Ana Wintergerst, Jesús A Arenas-Alatorre, Abigailt Flores-Ledesma","doi":"10.2334/josnusd.22-0139","DOIUrl":"https://doi.org/10.2334/josnusd.22-0139","url":null,"abstract":"Purpose: To evaluate the effect of three concentrations of bismuth trioxide (Bi2O3) on the biological and physicochemical properties of an experimental mineral trioxide aggregate-type (MTA-type) cement at different time points.Methods: Three experimental groups with white Portland cement containing 15, 20, or 25 wt% of Bi2O3 were assessed. Cellular proliferation in human periodontal ligament fibroblasts was evaluated with an MTT assay. Radiopacity, dimensional stability, pH, and compressive strength were evaluated at different time points.Results: Bismuth trioxide induced cell proliferation in the Bi15 and Bi25 groups in a time-dependent manner; pH was similar in all groups. Compressive strength was associated with time and bismuth concentration. Bi25 had significantly contracted at day 7 and expanded at day 14 (ANOVA P < 0.05, post hoc Tukey test P < 0.05).Conclusion: A higher Bi2O3 concentration had a negative effect on the physical properties of the cement at all time points.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10514289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Aging resistance of highly translucent zirconia ceramics with rapid sintering. 快速烧结高半透明氧化锆陶瓷的耐老化性能。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0264

Min Yan, Shinn-Jyh Ding, Cheng-Wei Lin, Cian-Li Wei, Yi-Wen Huang, Chun-Chuan Yang

{"title":"Aging resistance of highly translucent zirconia ceramics with rapid sintering.","authors":"Min Yan, Shinn-Jyh Ding, Cheng-Wei Lin, Cian-Li Wei, Yi-Wen Huang, Chun-Chuan Yang","doi":"10.2334/josnusd.22-0264","DOIUrl":"https://doi.org/10.2334/josnusd.22-0264","url":null,"abstract":"Purpose: Rapid sintering technology has become one of the most direct methods for shortening the manufacturing time of zirconia restorations. This study aimed to explore the aging resistance of rapid-sintered 5 mol% yttria-partially-stabilized zirconia (5Y-PSZ).Methods: Specimens were made from two types of 5Y-PSZ material and subjected to rapid sintering (RS) and conventional sintering (CS). After in vitro aging for 5 h, morphology observation, grain size measurement, and phase composition analysis were performed. The mechanical properties were evaluated by biaxial, three-point flexural tests, and the Vickers microhardness test. Results were analyzed by 3-way ANOVA.Results: Both the RS group and the CS group had a dense microstructure. The tested zirconia ceramics had different grain sizes, which were affected by the interaction between the sintering method and aging. Both groups revealed the same characteristic peaks of the cubic phase after aging. Regardless of the sintering method used, there was no significant difference in the mechanical properties of the tested zirconia before and after aging.Conclusion: The rapid-sintered 5Y-PSZ materials had a microstructure, phase composition and mechanical properties similar to those of conventional sintered materials. The characteristics of the materials prepared using the two sintering methods did not change significantly after aging.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10576574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Use of liquid-based cytology samples reveals genomic instability and cell death in patients undergoing orthodontic treatment. 液体细胞学样本的使用揭示了接受正畸治疗的患者的基因组不稳定性和细胞死亡。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-11 DOI: 10.2334/josnusd.22-0235

Iris Carrillo-Novia, Edith Lara-Carrillo, Olivia Torres-Bugarin, Adriana A Morales-Valenzuela, Elías N Salmerón-Valdés, Wael Hegazy-Hassan, Ulises Velázquez-Enríquez, Víctor H Toral-Rizo

{"title":"Use of liquid-based cytology samples reveals genomic instability and cell death in patients undergoing orthodontic treatment.","authors":"Iris Carrillo-Novia, Edith Lara-Carrillo, Olivia Torres-Bugarin, Adriana A Morales-Valenzuela, Elías N Salmerón-Valdés, Wael Hegazy-Hassan, Ulises Velázquez-Enríquez, Víctor H Toral-Rizo","doi":"10.2334/josnusd.22-0235","DOIUrl":"https://doi.org/10.2334/josnusd.22-0235","url":null,"abstract":"Purpose: To examine the use of liquid-based exfoliative cytology to determine the presence of genomic instability and cell death in the oral mucosa of patients with orthodontic appliances.Methods: Fifty-four oral mucosa samples were collected from 18 patients and divided into three stages: T0, before fixation of orthodontic appliances; T1, 25 days after appliance fixation; T2, 90 days after appliance fixation. All samples were Papanicolaou-stained and observed by microscopy (1,000 cells/sample) to ascertain the frequency of micronucleated cells (MN) and nuclear abnormalities (nuclear buds (NB), binucleated (BN), condensed chromatin (CC), karyorrhexis (KR), and karyolysis (KL)). Differences were analyzed statistically using the Mann-Whitney, Wilcoxon, Kruskal-Wallis and chi-squared tests.Results: After placement of orthodontic appliances, significant differences were observed for genomic instability biomarkers (MN and NB) and cell death (CC, KR and KL) (P < 0.05). Female patients and older patients exhibited a higher frequency of MN.Conclusion: Liquid-based cytology has revealed that orthodontic appliances induce genomic instability and cell death in epithelial tissue of the oral mucosa, facilitating sample preservation and yielding more than one preparation per sample. Future studies should investigate whether such cell damage can be reversed through cell repair or whether cell alterations evolve and lead to disease.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10545789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of thickness on the degree of conversion, monomer elution, depth of cure and cytotoxicity of bulk-fill composites. 厚度对大块填充复合材料转化程度、单体洗脱、固化深度和细胞毒性的影响。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-01 DOI: 10.2334/josnusd.22-0374

Zehra Süsgün Yıldırım, Ersan Eyiler, Zeliha G Bek Kürklü

{"title":"Effect of thickness on the degree of conversion, monomer elution, depth of cure and cytotoxicity of bulk-fill composites.","authors":"Zehra Süsgün Yıldırım, Ersan Eyiler, Zeliha G Bek Kürklü","doi":"10.2334/josnusd.22-0374","DOIUrl":"https://doi.org/10.2334/josnusd.22-0374","url":null,"abstract":"Purpose: Today, bulk-fill composites are used as a single layer with a thickness of up to 4-5 mm. However, is proper polymerization achieved with this increased thickness?Methods: This study was designed to investigate the effect of thickness on the degree of conversion (DC) (n = 6), the elution of monomers (n = 6), depth of cure (DoC) (n = 10) and cytotoxicity (n = 6) of the bulk-fill composites SDR Flow Plus (SDR), SonicFill2 SingleFill (SF) and ACTIVA Bioactive Restorative (ACT) in comparison to the conventional G-aenial Posterior (GC). Two-way analysis of variance (ANOVA) was used to assess the interaction between materials and surfaces, and one-way ANOVA and Tukey tests were used to compare the degree of conversion, monomer elution and cytotoxicity values (P < 0.05).Results: The highest DC was found at the top surface of SDR, while the lowest DC was found at SF. The V2 mm/V0 mm DoC ratios of the composites except ACTs were appropriate according to the threshold. None of the composites were cytotoxic on day 1.Conclusion: In bulk-fill composites, DC decreased and monomer elution increased with increasing depth. The V4 mm/V0 mm ratios of all bulk-fill groups were not appropriate. Additionally, only ACTs had a cell viability of <70% on day 7.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9219012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of different toothpastes on the color and whiteness of stained anterior composite resin. 不同牙膏对染色前部复合树脂颜色和白度的影响。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-01 DOI: 10.2334/josnusd.23-0106

Başak Yazkan, Ebru Yilmaz, Özge Gizem Yenidünya, Nilgün Akgül

{"title":"Effects of different toothpastes on the color and whiteness of stained anterior composite resin.","authors":"Başak Yazkan, Ebru Yilmaz, Özge Gizem Yenidünya, Nilgün Akgül","doi":"10.2334/josnusd.23-0106","DOIUrl":"10.2334/josnusd.23-0106","url":null,"abstract":"Purpose: To evaluate changes in the color of an anterior nanohybrid composite resin and differences in its whitening index after 30 days of brushing with six brands of whitening toothpaste in vitro to simulate the situation in individuals with high coffee consumption.Methods: Eighty-four disk-shaped resin specimens were prepared (shade A2). For initial staining, the samples were immersed in coffee solution for 14 days and then divided into eight groups for treatment with various toothpastes. Color was assessed at the baseline, after initial staining, and on days 7, 14, and 30 of the staining-and-brushing cycle. Color stability was evaluated based on the CIEDE2000 color difference (ΔE00), and differences in whiteness were determined using the whitening index for dentistry (WID).Results: The highest ΔE00 and ΔWID values were obtained with Colgate Herbal, followed by Opalescence Whitening and Crest Baking Soda and Peroxide, whereas the lowest values were obtained with distilled water, followed by Yotuel Pharma B5, on day 30 of the staining-and-brushing cycle.Conclusion: In terms of improving the color and whiteness of coffee-stained anterior nanohybrid composite resin, Colgate Herbal, Opalescence Whitening, and Crest Baking Soda and Peroxide yielded promising results after 30 days of continuous use.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41125687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of second-hand smoke exposure, quantified by salivary cotinine, with dental caries in Japanese adolescents. 二手烟暴露与日本青少年龋齿的关系，通过唾液可替宁来量化。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-01 DOI: 10.2334/josnusd.22-0388

Naohiro Takao, Michiko Furuta, Toru Takeshita, Shinya Kageyama, Takuro Goto, Myrna N Zakaria, Kenji Takeuchi, Yoshihisa Yamashita

{"title":"Association of second-hand smoke exposure, quantified by salivary cotinine, with dental caries in Japanese adolescents.","authors":"Naohiro Takao, Michiko Furuta, Toru Takeshita, Shinya Kageyama, Takuro Goto, Myrna N Zakaria, Kenji Takeuchi, Yoshihisa Yamashita","doi":"10.2334/josnusd.22-0388","DOIUrl":"https://doi.org/10.2334/josnusd.22-0388","url":null,"abstract":"Purpose: Second-hand smoke has adverse effects on oral health. This cohort study used a multilevel approach to investigate the association of second-hand smoke exposure, as determined by salivary cotinine level, with dental caries in adolescents.Methods: Data from 75 adolescents aged 11 or 12 years and 2,061 teeth without dental caries were analyzed in this study. Annual dental examinations to assess dental caries were conducted between 2018 and 2021. Salivary cotinine and Dentocult SM-Strip level were measured at baseline. Information on the smoking habits of parents, snack frequency, regular dental visits, and use of fluoride toothpaste was collected at baseline from parent-reported questionnaires.Results: During the 3-year follow-up, dental caries was noted in 21 adolescents and 43 teeth. Participants exposed to parental smoking had higher salivary cotinine levels than those whose parents did not smoke. The multilevel Cox regression model showed that a high salivary cotinine level was associated with the incidence of dental caries, after adjusting for potential confounding factors (hazard ratio, 3.39; 95% confidence interval 1.08-10.69).Conclusion: This study suggests that the risk of dental caries is higher for adolescents who have high salivary cotinine levels attributable to second-hand smoke exposure.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9219013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient receptor potential canonical 1 is a candidate treatment target for tongue squamous cell carcinoma by inhibiting growth and invasion through phosphatidylinositol 3-kinase and protein kinase B pathway. 瞬时受体电位canonical 1通过磷脂酰肌醇3-激酶和蛋白激酶B途径抑制舌鳞癌的生长和侵袭，是舌鳞癌的候选治疗靶点。

IF 1.9 4区医学

Journal of oral science Pub Date : 2023-01-01 DOI: 10.2334/josnusd.22-0376

Bing Zhou, Lei Jiang

{"title":"Transient receptor potential canonical 1 is a candidate treatment target for tongue squamous cell carcinoma by inhibiting growth and invasion through phosphatidylinositol 3-kinase and protein kinase B pathway.","authors":"Bing Zhou, Lei Jiang","doi":"10.2334/josnusd.22-0376","DOIUrl":"https://doi.org/10.2334/josnusd.22-0376","url":null,"abstract":"Purpose: Transient receptor potential canonical 1 (TRPC1) modulates tumor growth and invasion, however, its role in tongue squamous cell carcinoma (TSCC) is unclear. The aim of this study was to explore the effect of TRPC1 knockdown on cellular function and its underlying molecular mechanism in TSCC.Methods: TSCC cell lines were transfected with TRPC1 or negative control small interfering ribonucleic acids, and then PI3K activator was incubated after transfection.Results: TRPC1 was elevated in TSCC cell lines (including SCC-15, CAL-33, HSC-3, and YD-15) compared to control cells (all P < 0.05). Since TRPC1 was clearly increased in SCC-15 and YD-15 cells, they were selected for further study. In both YD-15 and SCC-15 cells, TRPC1 knockdown decreased cell proliferation at 48 h and 72 h (all P < 0.05), increased apoptosis (both P < 0.05), and declined invasion (both P < 0.05). Meanwhile, TRPC1 knockdown decreased phosphatidylinositol 3-kinase and protein kinase B phosphorylation (all P < 0.05). Additionally, the effect of TRPC1 knockdown on cell proliferation at 48 h and 72 h, apoptosis, and invasion was attenuated by PI3K activator (all P < 0.05).Conclusion: TRPC1 shows potential as a candidate treatment target, whose knockdown inhibits growth and invasion through inactivating PI3K/AKT pathway in TSCC.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9587138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0