Stefan Vulović, Markus B Blatz, Miloš Todorović, Aleksandra Milić Lemić, Aleksandar Todorović
{"title":"Impact of erosive and abrasive wear on the surface characteristics of hybrid ceramic-polymer dental materials.","authors":"Stefan Vulović, Markus B Blatz, Miloš Todorović, Aleksandra Milić Lemić, Aleksandar Todorović","doi":"10.2334/josnusd.24-0417","DOIUrl":"https://doi.org/10.2334/josnusd.24-0417","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the surface characteristics of hybrid ceramic-polymer materials before and after exposure to erosive and abrasive media.</p><p><strong>Methods: </strong>Samples were prepared from Vita Enamic (VE), Cerasmart (CS), VarseoSmile Crown plus (VSC), and VarseoSmile Temp (VST). Surface roughness (SR), scanning electron microscopy (SEM), and surface hardness (SH) analyses were performed before (T0) and after exposing the samples to gastric juice (GJ), toothbrushing (TB), or both (GJ TB) for a simulated period of one (T1) or two years (T2).</p><p><strong>Results: </strong>At T0, VSC and VST showed higher average (Ra) and maximum (Rz) roughness values, more homogeneous surfaces in SEM micrographs, and lower Vickers numbers (HV) than VE and CS. At T1 and T2, samples showed higher Ra values, greater surface damage on SEM micrographs, and reduced HV. The most pronounced changes were evident for GJ TB samples, followed in order by GJ (within VE and CS) and TB samples (within VSC and VST).</p><p><strong>Conclusion: </strong>VE and CS showed initially lower SR and higher SH, lower resistance to GJ, and higher resistance to TB than VSC and VST, which would be essential when fabricating restorations for patients who are particularly susceptible to dental erosion and abrasion.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fan Zhang, Mariko Hattori, Yuka I Sumita, Noriyuki Wakabayashi
{"title":"Color formulation algorithm of self-curing acrylic resin for the fabrication of facial prostheses.","authors":"Fan Zhang, Mariko Hattori, Yuka I Sumita, Noriyuki Wakabayashi","doi":"10.2334/josnusd.24-0344","DOIUrl":"https://doi.org/10.2334/josnusd.24-0344","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the law of color formation in various color mixtures of dental acrylic resin powder, with the aim of realizing quick and accurate color matching of facial prostheses.</p><p><strong>Methods: </strong>Self-curing acrylic resin in crown, gingival, and clear colors was used to prepare 62 disk-shaped specimens (diameter, 30 mm; thickness, 5 mm). For each specimen, 2 g of different colored powders were mixed with 1 g of liquid and polymerized. Color values (L*, a*, and b*) were measured using a spectrophotometer. First-order linear (M<sub>1</sub>), second-order quadratic (M<sub>2S</sub>), second-order interactive (M<sub>2I</sub>), and complete second-order (M<sub>2C</sub>) models were applied to predict the relationship between component concentrations and color values. Multiple linear regression analysis was performed to assess the fitness of the observed and predicted colors. Differences in fitness were evaluated using repeated measures analysis of variance.</p><p><strong>Results: </strong>M<sub>2C</sub> showed a significantly better fit between the observed and predicted values compared with the other models.</p><p><strong>Conclusion: </strong>The new model satisfied the requirements for clinical application. Using this formula, the mixing ratio of the powder of self-curing acrylic resin can easily be calculated to match skin colors. This formula will contribute to the fabrication of facial prostheses with suitable color, using dental material.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuuri Oku, Hideki Suito, Keiko Fujimoto, Adityakrisna Yoshi Putra Wigianto, Tetsuo Ichikawa, Kan Nagao
{"title":"Relationship between vertical hyoid bone position and swallowing function in older adults.","authors":"Yuuri Oku, Hideki Suito, Keiko Fujimoto, Adityakrisna Yoshi Putra Wigianto, Tetsuo Ichikawa, Kan Nagao","doi":"10.2334/josnusd.24-0409","DOIUrl":"https://doi.org/10.2334/josnusd.24-0409","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate swallowing function of older adults with lowered hyoid bone position.</p><p><strong>Methods: </strong>A total of 60 older adults (23 males and 37 females, mean age: 70.1 years) with no diagnosed dysphagia participated in the study. Participants were divided into two groups (High and Low group) based on the anterior point of the hyoid bone (H) with respect to the line connecting the most inferior and anterior point on the corpus of the third cervical vertebra (C3) and Menton (Me). Swallowing function was measured using the Repetitive Saliva Swallow Test (RSST), the Eating Assessment Tool (EAT-10), jaw-opening force (JOF) and tongue pressure (TP). Each group was studied for its relationship to swallowing function. Additionally, the RSST of males and females in the Low group were compared.</p><p><strong>Results: </strong>Males in the Low group had a significantly higher JOF (P = 0.009) in the RSST ≥ 5 group than in the RSST < 5 group. Females in the Low group had no measurements that showed significant differences between the RSST ≥ 4 and RSST < 4 groups.</p><p><strong>Conclusion: </strong>JOF may affect swallowing function in older males with lowered hyoid bone position.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decalcification of calcified tissues induced by inorganic polyphosphate in chondrogenic ATDC5 cells in the presence of insulin.","authors":"Tatsuaki Fujiki, Hiroshi Shiratsuchi, Yoshikazu Mikami, Taku Toriumi, Yoshiyuki Yonehara, Hiromasa Tsuda","doi":"10.2334/josnusd.24-0429","DOIUrl":"https://doi.org/10.2334/josnusd.24-0429","url":null,"abstract":"<p><strong>Purpose: </strong>Inorganic polyphosphate (PolyP), a polymer of orthophosphate, strongly promotes mineralized tissue formation. This study explored the conditions necessary for PolyP to induce calcified deposits in cartilage and assessed the role of insulin in modulating PolyP-induced tissue calcification.</p><p><strong>Methods: </strong>Murine chondrogenic ATDC5 cells were cultured under growth, mineralization, or PolyP-induced calcification conditions, with or without insulin. Calcified nodules were stained with Alizarin Red S, and conditioned media were analyzed for pH and lactate concentration using a pH meter and a lactate assay kit-WST.</p><p><strong>Results: </strong>PolyP treatment of ATDC5 cells led to calcified deposits by day 5, both with and without insulin. However, in the presence of insulin, these deposits were nearly fully decalcified by day 14. Conditioned media with insulin had a lower pH and a higher lactate concentration compared to those without insulin, with lactate levels sufficient to demineralize the PolyP-induced calcified deposits.</p><p><strong>Conclusion: </strong>These data suggest that treatment of ATDC5 chondrogenic cells with PolyP accelerates the formation of mineralized tissue. However, PolyP-induced calcified nodules undergo demineralization owing to lactate production by cells in the presence of insulin.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng Ni, Jun-Ichiro Jo, Ruonan Zhang, Yoshiya Hashimoto, Aki Nishiura
{"title":"Effect of substrate on the response of 3-dimensional periodontal ligament tissue to compressive stimulation.","authors":"Cheng Ni, Jun-Ichiro Jo, Ruonan Zhang, Yoshiya Hashimoto, Aki Nishiura","doi":"10.2334/josnusd.24-0366","DOIUrl":"https://doi.org/10.2334/josnusd.24-0366","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate the influence of substrates under the three-dimensional periodontal ligament (3D PDL) tissue on its biological functions after compressive stimulation.</p><p><strong>Methods: </strong>A 3D PDL tissue was created using a poly(L-lactic acid) (PLLA) porous scaffold impregnated with human periodontal ligament fibroblasts (hPDLFs). It was then placed on a polyetheretherketone (PEEK) substrate, which has a comparable elastic modulus to bone and was compressed (25 g/cm<sup>2</sup>) for 1, 3, and 7 days. The morphology and biological functions of the hPDLFs in the 3D PDL tissue on the PEEK substrate were evaluated and compared with those on the polystyrene (PS) substrate.</p><p><strong>Results: </strong>Compressive forces for the PLLA porous scaffold on the PEEK substrate were higher than those on the PS substrate. hPDLFs were present throughout the PLLA porous scaffold and there was no morphological change upon compressive stimulation. Increased expression of osteoclastogenic genes was observed after 3 days of compressive stimulation, while the level of these genes was increased by changing the substrate under the PDL tissue from PS to PEEK.</p><p><strong>Conclusion: </strong>The substrate placed under the PDL tissue during compressive stimulation affects the biological functions of hPDLFs.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of oral sciencePub Date : 2025-01-16Epub Date: 2024-12-15DOI: 10.2334/josnusd.24-0228
Nazmiye Şen
{"title":"Effect of graphene oxide on the biaxial flexural strength and translucency of ultrathin monolithic zirconia.","authors":"Nazmiye Şen","doi":"10.2334/josnusd.24-0228","DOIUrl":"10.2334/josnusd.24-0228","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate the influence of graphene oxide (GO) and hydrothermal aging on the biaxial flexural strength (BFS) and translucency (TP) of ultrathin monolithic zirconia with different yttria concentrations.</p><p><strong>Methods: </strong>Disc shaped specimens (n = 120) were milled using zirconia blocks (YZ-HT [HT], YZ-ST [ST], and YZ-XT [XT]) with a diameter of 15.0 mm and a thickness of 0.5 mm. Half of the specimens were immersed in 0.2 wt% GO-water dispersion (HTG, STG, and XTG) and subjected to hydrothermal aging for 10 h. The TP was measured using a reflection spectrophotometer and BFS was tested in a universal testing machine. Data were statistically analyzed with 2-way analysis of variance followed by post-hoc comparisons (α = 0.05).</p><p><strong>Results: </strong>The lowest mean TP was found in the group of STG aged for 10 h. Hydrothermal aging significantly decreased the TP values in the groups of HTG, STG, and XTG (P < 0.05). Significantly higher TP values were obtained in the groups of XT. Immersion in 0.2 wt% GO-water dispersion significantly improved the BFS values of STG, and XTG for the control and aged groups.</p><p><strong>Conclusions: </strong>GO leads to decreased translucency while improving BFS for highly translucent zirconia ceramics.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"30-34"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of oral sciencePub Date : 2025-01-16Epub Date: 2024-11-22DOI: 10.2334/josnusd.24-0278
Shatha S Zahran
{"title":"Impact of anatomical and clinical variables on the success of endodontic instrument fragment retrieval.","authors":"Shatha S Zahran","doi":"10.2334/josnusd.24-0278","DOIUrl":"10.2334/josnusd.24-0278","url":null,"abstract":"<p><strong>Purpose: </strong>Separation of instrument fragments can impede the progress of endodontic treatment, and effective management of this complication is crucial for treatment success. This study examined the factors that impact the success of retrieval of separated instrument fragments by postgraduate endodontic residents.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on a total of 224 teeth associated with instrument fragment separation that were managed by postgraduate residents specializing in endodontics between January 2020 and March 2024. Data were extracted from patient records, periapical radiographs, and clinical notes. Chi-squared test and t-test were employed to identify factors significantly influencing retrieval success. Associations between successful retrieval and variables were assessed using binary logistic regression models.</p><p><strong>Results: </strong>Fragment retrieval was successful in 32% of the examined cases. Retrieval was more likely to be successful for anterior teeth than for premolars and molars (P = 0.003). Fragment separation in the coronal third of the canal had a higher retrieval success rate (P < 0.001). Longer separated fragments were also associated with increased retrieval success (t = 3.035, P = 0.003).</p><p><strong>Conclusion: </strong>The study revealed that factors critically influencing the successful retrieval of separated instrument fragments included the tooth type, the level of separation within the canal, and the fragment length. These findings highlight the importance of careful case selection in order to optimize management outcomes.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"5-9"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of oral sciencePub Date : 2025-01-16Epub Date: 2024-11-22DOI: 10.2334/josnusd.24-0226
Naomi Igarashi, Hideki Takai, Yorimasa Ogata
{"title":"Effects of initial periodontal therapy on leucine-rich alpha-2 glycoprotein levels in saliva from Japanese patients with chronic periodontitis.","authors":"Naomi Igarashi, Hideki Takai, Yorimasa Ogata","doi":"10.2334/josnusd.24-0226","DOIUrl":"10.2334/josnusd.24-0226","url":null,"abstract":"<p><strong>Purpose: </strong>Examination of patients to detect periodontal disease is important for diagnosis and treatment planning, and accuracy of examination may be improved if salivary components can be applied for diagnosis. Leucine-rich α2 glycoprotein (LRG) is expressed in the serum of patients with inflammatory diseases, and salivary LRG may be applicable to the diagnosis of periodontal disease.</p><p><strong>Methods: </strong>To evaluate the effect of initial periodontal therapy (IPT) on clinical periodontal parameters such as probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), periodontal inflamed surface area (PISA), periodontal epithelial surface area (PESA), saliva samples were collected before and after IPT from 63 patients with chronic periodontitis. The amount of LRG protein in saliva was measured by enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>Salivary LRG levels of 30 patients with Stage III, Grade B or C periodontitis (Severe group) were higher than the LRG levels of 33 patients with Stage Ⅰ or Ⅱ, Grade A periodontitis (Mild group). LRG levels in the Severe group significantly decreased after IPT. Positive correlations were found between salivary LRG levels and mean PD, CAL, BOP rate, PISA and PESA.</p><p><strong>Conclusion: </strong>These results suggest that there is an association between salivary LRG levels and severity of periodontitis.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"10-13"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of oral sciencePub Date : 2025-01-16Epub Date: 2024-12-19DOI: 10.2334/josnusd.24-0306
Kübra Amaç, Bilge Turhan Bal, Mustafa Güngörmüş, Merve Bankoğlu Güngör, Seçil Karakoca Nemli
{"title":"In vitro cytotoxicity of dental implant cements on human gingival and mouse preosteoblast cell lines.","authors":"Kübra Amaç, Bilge Turhan Bal, Mustafa Güngörmüş, Merve Bankoğlu Güngör, Seçil Karakoca Nemli","doi":"10.2334/josnusd.24-0306","DOIUrl":"10.2334/josnusd.24-0306","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to evaluate the cytotoxicity of implant luting cements and to visualize the morphological changes in the cells.</p><p><strong>Methods: </strong>Seven experimental groups Cem Implant Cement (CIC), EsTemp Implant Cement (EIC), Harvard Implant Cement (HIC), MIS Crown Set Implant Cement (MCIC), Oxford Cem Implant Cement (OCIC), Premier Implant Cement (PIC), and Adhesor Carbofine (ZPC) were generated including one conventional, and six implant cements (n = 9). Specimens were applied to human fibroblast cell (HGF) and mouse pre-osteoblast cell line (MC3T3-E1) cells by direct contact and extract text methods. The extracts were prepared by sterilizing the discs under ultraviolet light for 24 h in a cell culture medium at 37°C, 5% CO, and 95% humidity. Cell lines were confluent in the cell culture module in 25 cm² and 75 cm² flasks in a carbon dioxide incubator with 5% CO and 95% humidity. Discs and extracts were placed in a 96-well plate. Cell viability was evaluated after 24 h by means of a cell proliferation assay with 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxyanilide (XTT assay).</p><p><strong>Results: </strong>Dual-cured OCIC and HIC cements comprising methacrylate and zinc oxide elicited relatively lower cytotoxicity than self-cure cements with various compositions. The OCIC revealed the highest cell viability (89%) in the extract method on the HGF cells. Immortalized MC3T3 cells showed more sensitivity to cement exposure than the primary HGF cells.</p><p><strong>Conclusion: </strong>All tested cements elicited a cytotoxic effect with differences depending on cell type and cement material in extract and direct contact methods. Dual polymerized semi-permanent cement (OCIC) showed higher cell viability in the extract method.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"24-29"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel air-polishing powder from natural eggshell.","authors":"Visaluk Punyawattananon, Wisarut Prawatvatchara, Niyom Thamrongananskul, Krisana Siralertmukul, Awiruth Klaisiri, Cheewin Towithelertkul","doi":"10.2334/josnusd.24-0222","DOIUrl":"10.2334/josnusd.24-0222","url":null,"abstract":"<p><strong>Purpose: </strong>This study compares the ability of extrinsic stain removal and surface roughness changes on tooth surfaces after using two different types of dental air polishing powder: Sodium bicarbonate and novel eggshell powder.</p><p><strong>Methods: </strong>For the study of extrinsic stain removal, twenty bovine teeth were soaked in coffee for extrinsic stain formation. Group 1 and Group 2 were polished with sodium bicarbonate powder and novel eggshell powder, respectively. The acquired stains of teeth were recorded as baseline, and color changes after cleaning with two different powders were also measured by colorimeter. Sixteen samples from eight human posterior teeth were used for the surface roughness test. Surface roughness values (S<sub>a</sub>) of two groups (sodium bicarbonate and novel eggshell powder) were measured by a contact-type profilometer before and after polishing with two types of powders.</p><p><strong>Results: </strong>The data showed that the average ΔE* value of the sodium bicarbonate group was higher than that of the novel eggshell powder group (P < 0.05). The average ΔS<sub>a</sub> value of the sodium bicarbonate group was higher than that of the novel eggshell powder group (P < 0.05).</p><p><strong>Conclusion: </strong>Sodium bicarbonate powder showed higher stain removal ability and surface roughness changes than the novel eggshell powder.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"1-4"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}