Journal of oral science最新文献

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Ex-vivo evaluation of intratubular antibacterial activity and biocompatibility of two hydraulic calcium silicate-based endodontic sealers. 两种液压硅酸钙基根管密封剂的管内抗菌活性和生物相容性的体外评价。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-16 DOI: 10.2334/josnusd.25-0024
Carlo Gaeta, Federica Veneri, Giulia Malvicini, Jessika Bertacchini, Francesco Cavani, Omar Shanableh, Eva Tollapi, Chiara Falciani, Simone Grandini, Luigi Generali
{"title":"Ex-vivo evaluation of intratubular antibacterial activity and biocompatibility of two hydraulic calcium silicate-based endodontic sealers.","authors":"Carlo Gaeta, Federica Veneri, Giulia Malvicini, Jessika Bertacchini, Francesco Cavani, Omar Shanableh, Eva Tollapi, Chiara Falciani, Simone Grandini, Luigi Generali","doi":"10.2334/josnusd.25-0024","DOIUrl":"10.2334/josnusd.25-0024","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the antibacterial activity of two hydraulic calcium silicate-based sealers, NeoSealer Flo and AH Plus Bioceramic, against Enterococcus faecalis (E. faecalis) biofilm and their biocompatibility with pre-osteoblastic cells.</p><p><strong>Methods: </strong>Thirty-one extracted human lower incisors with single canals were inoculated with E. faecalis, and their root canals were subjected to three types of filling: A) NeoSealer Flo (n = 10), B) AH Plus Bioceramic (n = 10), and C) positive control (n = 10), as well as one negative control. The teeth were embedded in resin and sectioned at their coronal, middle, and apical thirds, yielding 160 sections. Bacterial viability was assessed by confocal laser scanning microscopy using LIVE/DEAD staining. Biocompatibility was evaluated using the bicinchoninic acid protein assay and sodium dodecyl sulfate-polyacrylamide gel electrophoresis.</p><p><strong>Results: </strong>NeoSealer Flo and AH Plus Bioceramic showed comparable antibacterial activity. In the coronal third of the tooth, viable bacteria were estimated at 44.1 ± 4.0% and 43.5 ± 4.0%, respectively, versus 85.7 ± 5.2% in controls. Similar results were obtained in the middle and apical thirds. Viability was significantly higher in the coronal third (P < 0.05). No significant differences in cell number or protein expression were observed between the sealers and the controls (P > 0.05).</p><p><strong>Conclusion: </strong>Both sealers demonstrated similar antibacterial effectiveness and biocompatibility, with greater bacterial viability in the coronal region.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"51-58"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preschool and primary school teachers' knowledge of emergency management of traumatic dental injuries: a cross-sectional study. 学前和小学教师创伤性牙损伤应急管理知识的横断面研究。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-17 DOI: 10.2334/josnusd.25-0425
Hamide Comert, Merve Ozdemir, Ecem Kuscu Baran
{"title":"Preschool and primary school teachers' knowledge of emergency management of traumatic dental injuries: a cross-sectional study.","authors":"Hamide Comert, Merve Ozdemir, Ecem Kuscu Baran","doi":"10.2334/josnusd.25-0425","DOIUrl":"10.2334/josnusd.25-0425","url":null,"abstract":"<p><strong>Purpose: </strong>Teachers frequently serve as primary first responders when traumatic dental injuries (TDIs) occur in schools. Immediate management is critical for prognosis, particularly in avulsion cases. This study aimed to assess preschool and primary school teachers' knowledge of emergency TDI management and their awareness of the ToothSOS mobile application, a resource providing evidence-based guidance.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted among 427 preschool and primary school teachers in Turkey between May and June 2025. An online questionnaire, based on international guidelines and validated by expert review, collected data on demographics, TDI management knowledge, and ToothSOS awareness. Statistical analyses were performed using non-parametric tests (P < 0.05).</p><p><strong>Results: </strong>The median knowledge score was 3 (range: 0-8). Few teachers correctly identified immediate replantation or storage in milk as appropriate actions for avulsed permanent teeth. Although awareness of the ToothSOS was extremely low, over half of the participants expressed willingness to use it. Significantly higher knowledge scores were observed among teachers with prior trauma education.</p><p><strong>Conclusion: </strong>Teachers demonstrated insufficient knowledge of emergency management of TDIs and limited awareness of digital support tools. Incorporating structured trauma education and accessible educational technologies into teacher training may support teachers' preparedness and decision-making in dental trauma emergencies.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"106-111"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of CAD-CAM block material and thickness on the translucency parameter and polymerization of light-cured resin cement. CAD-CAM砌块材料及厚度对光固化树脂水泥透光性参数及聚合的影响。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-03 DOI: 10.2334/josnusd.25-0298
Didem Esen Çiftçibaşı, Ayşe Dündar, Çağatay Barutçugil
{"title":"Effect of CAD-CAM block material and thickness on the translucency parameter and polymerization of light-cured resin cement.","authors":"Didem Esen Çiftçibaşı, Ayşe Dündar, Çağatay Barutçugil","doi":"10.2334/josnusd.25-0298","DOIUrl":"10.2334/josnusd.25-0298","url":null,"abstract":"<p><strong>Purpose: </strong>This study assessed the association of computer-aided design-computer-aided manufacturing (CAD-CAM) block material and thickness with the translucency parameter and polymerization of a light-cured resin cement.</p><p><strong>Methods: </strong>Specimens were prepared from CAD-CAM blocks (Lava Ultimate, IPS Empress CAD, Celtra Duo) with thicknesses of 0.5, 1, and 2 mm (n = 10 each). The translucency parameter (TP) of the blocks was calculated with a spectrophotometer. A total of 100 resin cement specimens were prepared from Calibra Veneer, and the microhardness of the resin cement was measured with a Vickers microhardness device.</p><p><strong>Results: </strong>In all CAD-CAM blocks, TP decreased as thickness increased (P < 0.05). Microhardness values for the top surface were lower than that of the control group for all groups except the LU 0.5 mm group (P < 0.05). Microhardness values for the bottom surface were lower than that of the control group in all groups (P < 0.05). In addition, microhardness was lower immediately after polymerization than at 24 h after polymerization in all groups (P < 0.05).</p><p><strong>Conclusion: </strong>The microhardness of a light-cured resin cement varied in relation to the material and thickness of the CAD-CAM block and was higher at 24 h after polymerization.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"82-86"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of different chelating agents on the microhardness, surface roughness, and adhesion of biodentine to root dentin. 不同螯合剂对生物牙本质显微硬度、表面粗糙度及与牙根黏附的影响。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-14 DOI: 10.2334/josnusd.25-0372
Aslı Özdemir, Mevlüt S Ocak
{"title":"Influence of different chelating agents on the microhardness, surface roughness, and adhesion of biodentine to root dentin.","authors":"Aslı Özdemir, Mevlüt S Ocak","doi":"10.2334/josnusd.25-0372","DOIUrl":"10.2334/josnusd.25-0372","url":null,"abstract":"<p><strong>Purpose: </strong>This in vitro study evaluated the effects of different chelating agents on dentin properties influencing the adhesion of calcium silicate-based biomaterials. The effects of 9% etidronic acid and 0.2% chitosan nanoparticles on the microhardness, surface roughness, and push-out bond strength of Biodentine were assessed.</p><p><strong>Methods: </strong>Seventy-five extracted maxillary incisors were divided into three groups according to the final irrigation protocol: 9% 1-hydroxyethylidene-1,1-bisphosphonate (HEBP), 0.2% chitosan, or 0.9% saline (control). Dentin microhardness (Vickers hardness number) and surface roughness (Ra, µm) were measured before and after irrigation. For push-out testing, standardized cavities in 60 dentin discs were filled with Biodentine and stored for 24 h at 37°C and 100% humidity. Failure modes were examined under a stereomicroscope. Data were analyzed using one-way Analysis of Variance (ANOVA), Tukey Honestly Significant Difference (HSD), Kruskal-Wallis, and paired t-tests (P < 0.05).</p><p><strong>Results: </strong>All groups showed a significant reduction in microhardness (P < 0.001), with the greatest reduction observed in HEBP. Surface roughness increased significantly and was highest in HEBP (P < 0.001). Push-out bond strength was higher in HEBP than control (P < 0.01), with no difference between HEBP and chitosan (P > 0.05).</p><p><strong>Conclusion: </strong>Both agents improved Biodentine adhesion; however, chitosan caused milder dentin alterations, indicating greater potential for dentin preservation.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"71-76"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the frictional resistance of 3D-printed brackets and conventional brackets. 3d打印支架与传统支架的摩擦阻力比较。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-13 DOI: 10.2334/josnusd.25-0321
Ahmet Yıldırım, Ali Kiki
{"title":"Comparison of the frictional resistance of 3D-printed brackets and conventional brackets.","authors":"Ahmet Yıldırım, Ali Kiki","doi":"10.2334/josnusd.25-0321","DOIUrl":"10.2334/josnusd.25-0321","url":null,"abstract":"<p><strong>Purpose: </strong>This study attempted to compare frictional resistance among three-dimensional (3D) printed resin brackets, and also with conventional metal and ceramic brackets under in vitro conditions.</p><p><strong>Methods: </strong>3D bracket designs were created digitally and converted to stereolithography (STL) file format. Subsequently, brackets were produced using a FormLabs 3B+ printer using Permanent Crown and Biomed Clear resins. Half of these 3D-printed brackets were aged by thermal cycling, and then the frictional resistances of aged resin, non-aged resin, ceramic and metal brackets were measured using a universal testing machine.</p><p><strong>Results: </strong>Shrinkage was 5.41% for Permanent Crown brackets and 7.84% for Biomed Clear brackets. Resin-based brackets produced by 3D printing demonstrated the highest frictional resistance. After the aging process, the frictional resistance of the 3D-printed brackets was reduced. Frictional resistance was lowest for the stainless steel wire and stainless steel bracket combination, and highest for the beta-titanium wire and resin bracket combinations (P < 0.05).</p><p><strong>Conclusion: </strong>As the Permanent Crown resin bracket demonstrated frictional resistance comparable to ceramic brackets after aging, advances in more durable 3D printing materials with improved surface properties are expected to further enhance the clinical applicability of 3D-printed brackets.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"99-105"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative evaluation of the effectiveness of metal artifact reduction using a dedicated phantom across cone-beam computed tomography devices. 定量评估金属伪影减少的有效性,使用专用的幻像跨锥束计算机断层扫描设备。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-13 DOI: 10.2334/josnusd.25-0350
Tomoyuki Sadakane, Ataru Yabe
{"title":"Quantitative evaluation of the effectiveness of metal artifact reduction using a dedicated phantom across cone-beam computed tomography devices.","authors":"Tomoyuki Sadakane, Ataru Yabe","doi":"10.2334/josnusd.25-0350","DOIUrl":"10.2334/josnusd.25-0350","url":null,"abstract":"<p><strong>Purpose: </strong>To propose and validate the residual ratio of the metal artifact area (ResRaMAA) as an objective and practical metric for quantitative evaluation of the effectiveness of metal artifact reduction (MAR) in cone-beam computed tomography (CBCT) using a dedicated phantom.</p><p><strong>Methods: </strong>A phantom enabling variation in the number and positioning of titanium rods was scanned under four rod configurations using three CBCT systems. The metal artifact area (MAA) was measured with MAR turned off (MAR-Off) and on (MAR-On), and the two values were used to determine the ResRaMAA.</p><p><strong>Results: </strong>MAA values indicated a proportional relationship between MAR-Off and MAR-On. The proportionality coefficient, total ResRaMAA, ranged from 14% to 18%, significantly differing from 0% and 100%. Lower and upper ResRaMAA distributions differed significantly within the same device. Device-related differences were suggested, but not confirmed statistically. Additionally, titanium rod shapes in MAR-On data varied by device and metal rod configuration.</p><p><strong>Conclusion: </strong>ResRaMAA was able to quantify MAR effectiveness in reducing metal artifacts (MAs) caused by titanium rods and revealed significant differences between the lower and upper MA regions. ResRaMAA provides a simple, practical metric for objective evaluation of MAR performance.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"87-92"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of thermoplastic resin clasps on force and torsional moment on the abutment tooth during removal. 热塑性树脂卡环对移除基牙时力和扭转力矩的影响。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-02-27 DOI: 10.2334/josnusd.25-0369
Shohgo Shibata, Nagame Mizokoshi, Hidemasa Shimpo, Noboru Kawamura, Yasunori Suzuki, Chikahiro Ohkubo
{"title":"Effects of thermoplastic resin clasps on force and torsional moment on the abutment tooth during removal.","authors":"Shohgo Shibata, Nagame Mizokoshi, Hidemasa Shimpo, Noboru Kawamura, Yasunori Suzuki, Chikahiro Ohkubo","doi":"10.2334/josnusd.25-0369","DOIUrl":"10.2334/josnusd.25-0369","url":null,"abstract":"<p><strong>Purpose: </strong>Non-metal clasp dentures (NMCDs) employing gingiva-colored thermoplastic resin clasps are widely used to enhance the aesthetics of removable partial dentures (RPDs). This study investigated the forces and torsional moments exerted on abutment teeth during removal of thermoplastic resin clasps and compared them with those generated by conventional cobalt-chromium (Co-Cr) alloy clasps.</p><p><strong>Methods: </strong>Clasps fabricated from Co-Cr alloy and thermoplastic resin with different undercut depths were examined. Fitness accuracy was evaluated, and tensile tests were performed using a miniature six-axis force/torque sensor. Removal forces and torsional moments acting on the abutment tooth were analyzed along the buccolingual (X-axis), mesiodistal (Y-axis), and vertical (Z-axis) directions. Statistical analyses were conducted to compare materials and undercut conditions.</p><p><strong>Results: </strong>Fitness accuracy ranged from 85 to 130 µm for both clasp types. The thermoplastic resin clasp with a 0.25 mm undercut demonstrated significantly better fitness than the Co-Cr alloy clasp (P < 0.05). Resin clasps with a 0.5 mm proximal undercut generated greater removal forces and torsional moments than metal clasps and resin clasps with smaller undercuts. Increasing the proximal undercut depth in resin clasps resulted in increased retention forces, lateral forces, and torsional moments.</p><p><strong>Conclusion: </strong>Thermoplastic resin clasps with larger proximal undercuts exert greater lateral forces and torsional moments on abutment teeth during removal. Therefore, appropriate selection of undercut depth is essential to reduce potentially harmful stresses while maintaining adequate retention in NMCDs.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"77-81"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shear bond strength of resin luting material to zirconia using a pre-sintered coating approach. 用预烧结涂层法研究树脂材料与氧化锆的剪切结合强度。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-11 DOI: 10.2334/josnusd.25-0397
Satomi Arai, Kei Kubochi, Keisuke Hoshino, Futoshi Komine
{"title":"Shear bond strength of resin luting material to zirconia using a pre-sintered coating approach.","authors":"Satomi Arai, Kei Kubochi, Keisuke Hoshino, Futoshi Komine","doi":"10.2334/josnusd.25-0397","DOIUrl":"10.2334/josnusd.25-0397","url":null,"abstract":"<p><strong>Purpose: </strong>The effect of a feldspathic porcelain coating applied before or after zirconia sintering on the shear bond strength between a resin luting agent and zirconia was evaluated.</p><p><strong>Methods: </strong>Pre-sintered and fully sintered zirconia specimens were coated with feldspathic porcelain and divided into three surface treatment groups: no treatment, airborne-particle abrasion, and hydrofluoric acid etching. The specimens were bonded using a dual-polymerizing resin luting agent and subjected to 0 or 5,000 thermocycles. The shear bond strength was measured. The fracture modes were analyzed microscopically. The surface morphology and composition were examined by scanning electron microscopy (SEM) and X-ray diffraction.</p><p><strong>Results: </strong>Before thermocycling, both airborne-particle abrasion and hydrofluoric acid etching significantly increased the bond strength compared with no treatment. After thermocycling, airborne-particle abrasion maintained the highest bond durability, while hydrofluoric acid etching showed a marked decrease. SEM revealed that airborne-particle abrasion produced a rough surface favorable for micromechanical retention, whereas hydrofluoric acid etching resulted in smoother morphology.</p><p><strong>Conclusion: </strong>Airborne-particle abrasion effectively enhanced and preserved the bond strength between the resin luting agent and feldspathic porcelain-coated zirconia, regardless of the coating sequence. Hydrofluoric acid etching was ineffective after thermocycling, likely due to surface precipitation that occurred during firing.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"66-70"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stage-specific analysis of targeted microRNAs in oral squamous cell carcinoma and their association with the use of naswar. 口腔鳞状细胞癌中靶向microrna的分期特异性分析及其与纳司瓦使用的关系。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-02-25 DOI: 10.2334/josnusd.25-0294
Nasiha Bashir, Sajjad Ahmad, Fatima Iqbal, Laiba Fayyaz, Tehmina Naushin
{"title":"Stage-specific analysis of targeted microRNAs in oral squamous cell carcinoma and their association with the use of naswar.","authors":"Nasiha Bashir, Sajjad Ahmad, Fatima Iqbal, Laiba Fayyaz, Tehmina Naushin","doi":"10.2334/josnusd.25-0294","DOIUrl":"10.2334/josnusd.25-0294","url":null,"abstract":"<p><strong>Purpose: </strong>The present study was conducted to correlate the expression of the targeted microRNAs with the stages of oral squamous cell carcinoma (OSCC), and to evaluate expression differences among naswar users with and without OSCC.</p><p><strong>Methods: </strong>This prospective study examined saliva from 32 healthy controls, 32 habitual naswar users without OSCC, and 96 OSCC patients who were further categorized into three groups - stage I+II, stage III, and stage IV - each comprising 32 patients. Using quantitative real-time polymerase chain reaction (RT-PCR), the expression status of the targeted miRNAs was assessed for its association with OSCC stages and naswar use. Receiver operating characteristic (ROC) curve analysis was used to assess the discriminative potential of candidate miRNAs between stages.</p><p><strong>Results: </strong>Significant correlations were observed for all of the targeted miRNAs. Highly significant (P < 0.001) pairwise differences in expression were detected among upregulated miRNAs (miR-21, miR-31, and miR-146a) across all stages of OSCC. In contrast, for downregulated miR-375, a highly significant difference was found between the control group and stage I+II. Pairwise significance for naswar use was highest for miR-146a.</p><p><strong>Conclusion: </strong>Among the targeted miRNAs, miR-146a exhibited the highest potential for discriminating between the stages of OSCC, and use as a screening tool for any naswar-linked risk.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"59-65"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147307054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro evaluation of microleakage in a tricalcium silicate-based cement matured for 12 min or 24 h and covered with glass ionomer cement or resin composite. 体外评价硅酸盐三钙基水泥成熟12 min或24 h后覆盖玻璃离子水门柱或树脂复合材料的微渗漏。
IF 1.7 4区 医学
Journal of oral science Pub Date : 2026-04-16 Epub Date: 2026-03-13 DOI: 10.2334/josnusd.25-0236
Wichida Chaweewannakorn, Chanoknan Karuna, Nightingale Kasemsook, Woramet Kittithummaroj, Narinee Chinajitphan, Nirada Dhanesuan, Kwanchanok Youcharoen
{"title":"In vitro evaluation of microleakage in a tricalcium silicate-based cement matured for 12 min or 24 h and covered with glass ionomer cement or resin composite.","authors":"Wichida Chaweewannakorn, Chanoknan Karuna, Nightingale Kasemsook, Woramet Kittithummaroj, Narinee Chinajitphan, Nirada Dhanesuan, Kwanchanok Youcharoen","doi":"10.2334/josnusd.25-0236","DOIUrl":"10.2334/josnusd.25-0236","url":null,"abstract":"<p><strong>Purpose: </strong>To compare microleakage of calcium silicate-based cement (Biodentine, BD) used alone or covered with glass ionomer cement (GIC) or resin composite (RC) and matured for 12 min (12mBD) or 24 h (24hBD).</p><p><strong>Methods: </strong>Seventy-two extracted premolars with class I cavities were divided into two groups (n = 36) based on BD maturation time (12 min and 24 h). Each group was then subdivided by restoration type into three subgroups (n = 12 each): BD only, BD + GIC, and BD + RC. After pH cycling, thermocycling, and methylene blue immersion, microleakage was assessed with a stereomicroscope. Data were analyzed using two-way ANOVA and the chi-square test (P < 0.05).</p><p><strong>Results: </strong>Microleakage scoring showed that 12mBD + RC had the least dye penetration, significantly less than 24hBD and 24hBD + GIC. The 12mBD + RC group also had the lowest microleakage proportion. For both BD and BD + GIC, microleakage proportions were significantly lower after 12 min of maturation than after 24 h of maturation.</p><p><strong>Conclusion: </strong>BD matured for 12 min exhibited microleakage equal to or less than that of the 24-h groups. Additionally, sealing was better for restorations with RC over BD than for those with BD alone or BD combined with GIC.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"93-98"},"PeriodicalIF":1.7,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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