Journal of oral science最新文献_第2页

Orthodontic tooth movement following bone regeneration with modified bone graft materials treated with a biosilane coupling agent. 生物硅烷偶联剂改性骨移植材料骨再生后正畸牙齿移动。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-16 Epub Date: 2025-10-27 DOI: 10.2334/josnusd.25-0193

Ryota Koike, Takenori Sato, Masahiro Takahashi, Katsura Ohashi, Tomotaro Nihei, Tetsutaro Yamaguchi, Keisuke Handa

{"title":"Orthodontic tooth movement following bone regeneration with modified bone graft materials treated with a biosilane coupling agent.","authors":"Ryota Koike, Takenori Sato, Masahiro Takahashi, Katsura Ohashi, Tomotaro Nihei, Tetsutaro Yamaguchi, Keisuke Handa","doi":"10.2334/josnusd.25-0193","DOIUrl":"10.2334/josnusd.25-0193","url":null,"abstract":"Purpose: The impact of bone regeneration using bone graft materials on orthodontic tooth movement (OTM) remains unclear. This study was designed to histologically and biologically evaluate the influence of bone graft materials treated with a biosilane coupling agent on early bone formation and their effect on OTM.Methods: Maxillary first molars of 4-week-old male Wistar rats were extracted, followed by alveolar bone regeneration using either carbonate apatite (Cytrans granules; Cyt) or biosilane-treated Cytrans (DI6M-Cyt). After 2 weeks, nickel-titanium (Ni-Ti) closed-coil springs were applied to exert mesial traction on the second molars, inducing OTM for 14 or 28 days. Bone formation characteristics and tooth movement patterns were evaluated via micro-computed tomography (micro-CT), histological analysis (hematoxylin and eosin [H&E] and tartrate-resistant acid phosphatase [TRAP] staining), and nanoindentation testing.Results: Initial bone formation was noted in the DI6M-Cyt group relative to the untreated group, the rigidity of the newly formed bone approaching that of natural bone, thus inhibiting aberrant tooth movement following OTM. Furthermore, osteoclast activity was appropriately regulated, maintaining balanced bone remodeling.Conclusion: These findings indicate that biosilane-treated bone graft materials enhance bone regeneration and that the newly formed bone does not impede OTM.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145372789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between oral health and nutritional intake among older denture wearers. 老年假牙佩戴者口腔健康与营养摄入之间的关系。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-16 Epub Date: 2025-12-17 DOI: 10.2334/josnusd.25-0291

Takamasa Yoshida, Kensuke Nishio, Yu Yasuda, Shinji Okada, Tomoka Ito, Toshimitsu Iinuma

{"title":"Association between oral health and nutritional intake among older denture wearers.","authors":"Takamasa Yoshida, Kensuke Nishio, Yu Yasuda, Shinji Okada, Tomoka Ito, Toshimitsu Iinuma","doi":"10.2334/josnusd.25-0291","DOIUrl":"10.2334/josnusd.25-0291","url":null,"abstract":"Purpose: This study examined the association between oral health and nutritional intake among older denture wearers.Methods: Oral health parameters were evaluated in 114 denture wearers, including the number of remaining teeth (<20 or ≥20), posterior occlusal support (Eichner classification A1-B3 or B4-C3), objective masticatory assessment (glucose concentration: <100 or ≥100 mg/dL), subjective masticatory assessment (self-reported masticatory problems), and occlusal force (<500 or ≥500 N). Nutritional intake was assessed using a brief self-administered diet history questionnaire. Differences in nutritional intake according to oral health parameters were assessed using multiple regression analysis.Results: Fewer remaining teeth were associated with higher total fat (β = 0.207, P = 0.038) and plant fat (β = 0.242, P = 0.017) intakes, and with lower carbohydrate (β = -0.264, P = 0.026) and cereal (β = -0.320, P = 0.002) intakes. The presence of masticatory problems and absence of posterior occlusal support were associated with lower intakes of plant protein (β = -0.311, P = 0.002) and meat (β = -0.232, P = 0.022), respectively.Conclusion: Among older denture wearers, denture design-related factors, such as the number of remaining teeth and posterior occlusal support, were associated with more nutritional intake items than oral function-related parameters.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"19-24"},"PeriodicalIF":1.7,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enamel matrix derivative-induced cementoblast differentiation via Wnt/β-catenin signaling in human periodontal ligament cells. 釉质基质衍生物通过Wnt/β-catenin信号传导诱导人牙周韧带细胞成牙骨质分化。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-16 Epub Date: 2025-12-03 DOI: 10.2334/josnusd.25-0217

Ju-Chan Maeng, Su-Kyeong Son, Jung-Sun Moon, Dong-Wook Yang, Sun-Hun Kim, Min-Seok Kim

{"title":"Enamel matrix derivative-induced cementoblast differentiation via Wnt/β-catenin signaling in human periodontal ligament cells.","authors":"Ju-Chan Maeng, Su-Kyeong Son, Jung-Sun Moon, Dong-Wook Yang, Sun-Hun Kim, Min-Seok Kim","doi":"10.2334/josnusd.25-0217","DOIUrl":"10.2334/josnusd.25-0217","url":null,"abstract":"Purpose: Cementum is a specialized calcified tissue produced by cementoblasts, which play a key role in periodontal regeneration. Enamel matrix derivative (EMD) is an agent currently employed for treatment of periodontal disease, although its molecular action mechanism remains unclear. The present study aimed to investigate the effects of EMD on cementoblast differentiation and the involvement of Wnt/β-catenin signaling in human periodontal ligament (hPDL) cells.Methods: Primary hPDL cells were treated with EMD, and the expression of cementum-related markers was evaluated. The role of Wnt/β-catenin signaling was assessed using IWP-2, a Wnt inhibitor. A luciferase reporter assay was conducted to identify regulatory elements within the cementum protein 1 (CEMP1) promoter.Results: EMD upregulated the expression of CEMP1 and cementum attachment protein. This effect was attenuated by IWP-2, indicating Wnt/β-catenin involvement. A T-cell factor binding site was identified within the CEMP1 promoter. EMD increased the expression of osterix and runt-related transcription factor 2 (Runx2) slightly, but decreased the levels of osteocalcin and osteopontin. No mineralization enhancement was observed based on alkaline phosphatase activity and Alizarin Red S stainingConclusion: EMD promotes early-stage cementoblast differentiation via Wnt/β-catenin signaling but has limited effects on late-stage maturation, offering new insights into the regenerative potential of EMD for periodontal therapy.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"12-18"},"PeriodicalIF":1.7,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of vat polymerization methods on surface and bonding behavior of additive manufactured dental resins. 还原聚合方法对添加剂制牙用树脂表面和粘接性能的影响。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-16 Epub Date: 2025-11-15 DOI: 10.2334/josnusd.25-0161

İrem B Yeşil Kurt, Nursena Öztemel, Almira A Diken Türksayar

{"title":"Influence of vat polymerization methods on surface and bonding behavior of additive manufactured dental resins.","authors":"İrem B Yeşil Kurt, Nursena Öztemel, Almira A Diken Türksayar","doi":"10.2334/josnusd.25-0161","DOIUrl":"10.2334/josnusd.25-0161","url":null,"abstract":"Purpose: To investigate the surface roughness (Ra), shear bond strength (SBS), and Vickers hardness number (VHN) of additive manufactured interim resins manufactured through different vat polymerization techniques.Methods: Samples were divided into four groups; additive manufacturing technology (Stereolithography:S-FL; Digital light processing:D-AS; Liquid crystal display:L-PH) and subtractive manufacturing technology (Polymethylmethacrylate: MP) (n = 10). After polishing, the Ra values were measured and resin material was then applied. Following thermocycling, SBS tests and VHN tests were carried out. The obtained data were evaluated using one-way analysis of variance (ANOVA) (a = 0.05).Results: Significant differences were observed between the groups for SBS (P = 0.02) and VHN (P < 0.001), whereas the Ra values were not statistically significant (P = 0.148). D-AS and L-PH had higher and similar SBS (P = 1.000) while MP had statistically lower SBS. D-AS demonstrated higher VHN than all groups (P < 0.001) with the exception of S-FL (P = 0.831). MP had lower VHN than all groups (P < 0.01) other than L-PH (P = 0.143).Conclusion: All fabrication methods had clinically acceptable SBS values, L-PH and D-AS had higher results. D-AS demonstrated superiority in terms of VHN, all groups exhibited comparable Ra values.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":" ","pages":"7-11"},"PeriodicalIF":1.7,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of Stevens-Johnson syndrome triggered by Mycoplasma infection. 由支原体感染引发的史蒂文斯-约翰逊综合征1例。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0254

Atsushi Uenoyama, Hideaki Hirai, Yuko Saito, Tetsuo Kiguchi, Saori Takashima, Kei Tomihara

引用次数: 0

Defensin-4 as a proposed diagnostic marker for gingivitis and periodontitis. 防御素-4作为牙龈炎和牙周炎的诊断标志物。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0335

Ho-Jin Jeong, Young Sun Hwang

{"title":"Defensin-4 as a proposed diagnostic marker for gingivitis and periodontitis.","authors":"Ho-Jin Jeong, Young Sun Hwang","doi":"10.2334/josnusd.25-0335","DOIUrl":"https://doi.org/10.2334/josnusd.25-0335","url":null,"abstract":"Purpose: This study aimed to provide evidence supporting defensin-4 (DEFA4) as a potential diagnostic marker for periodontal diseases.Methods: Proteomic analysis of gingival crevicular fluid (GCF) collected from patients with gingivitis and periodontitis was performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). In addition, immortalized gingival fibroblasts (IGFs) were stimulated with Porphyromonas gingivalis lipopolysaccharide (PG-LPS) and co-cultured with oral bacteria isolated from periodontitis patients.Results: LC-MS/MS analysis of GCF from patients with periodontal disease revealed markedly elevated levels of DEFA4. The expression of DEFA4 in immortalized gingival fibroblasts (IGFs) was significantly increased following stimulation with Porphyromonas gingivalis lipopolysaccharide (PG-LPS) and co-culture with oral bacteria isolated from periodontitis patients. Furthermore, the culture supernatant of IGFs co-cultured with periodontitis-associated oral bacteria showed increased levels of GRO, GRO-α (CXCL1), IL-1α, IL-6, IL-8, and angiogenin.Conclusion: DEFA4 expression is strongly enhanced by the inflammatory environment of gingival cells influenced by oral bacteria, supporting its potential utility as a diagnostic marker for monitoring periodontal diseases.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"68 1","pages":"35-39"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro evaluation of color stability of non-pigmented maxillofacial silicone elastomer immersed in condiments. 无色素颌面硅弹性体浸泡在调味品中颜色稳定性的体外评价。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0309

Bilal L Alkrayem, Mariko Hattori, Ahmed Sameir M Ali, Mihoko Haraguchi, Mai Murase, Noriyuki Wakabayashi

{"title":"In vitro evaluation of color stability of non-pigmented maxillofacial silicone elastomer immersed in condiments.","authors":"Bilal L Alkrayem, Mariko Hattori, Ahmed Sameir M Ali, Mihoko Haraguchi, Mai Murase, Noriyuki Wakabayashi","doi":"10.2334/josnusd.25-0309","DOIUrl":"https://doi.org/10.2334/josnusd.25-0309","url":null,"abstract":"Purpose: Maxillofacial silicone prostheses restore facial appearance, and those in the perioral region contact food that may affect their color. This study evaluated how common condiments influence the color stability of silicone elastomers.Methods: Thirty-two non-pigmented silicone specimens were divided into four groups (n = 8) and immersed in water, ketchup, soy sauce, and vegetable sauce. A spectrophotometer measured color at baseline and after 7 and 14 days. ΔE00 values were calculated using the CIEDE2000 formula, and data were analyzed statistically (α = 0.05).Results: At 14 days, ketchup caused the greatest discoloration (ΔE00 = 8.11 ± 0.21), followed by vegetable sauce (2.27 ± 0.28), soy sauce (0.78 ± 0.17), and water (0.34 ± 0.16). The differences between groups were significant (P < 0.001). Ketchup caused more discoloration than the other condiments, while soy sauce and vegetable sauce differed only at 14 days. All condiments differed from water in relation to discoloration. Color changes included darkening and yellowing with ketchup, greenish-blue tinting with soy sauce, and darkening with vegetable sauce; water caused no change in color.Conclusion: Pigments in condiments can affect the aesthetics of maxillofacial prostheses. Patients should thus receive dietary and hygiene guidance to extend the lifespan of prostheses.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"68 1","pages":"25-29"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unstable sitting postures affect head and neck muscle activity during mastication. 不稳定的坐姿会影响咀嚼时头颈部肌肉的活动。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0366

Motoyoshi Morishita, Mizuho Ohta, Nobuhiro Okamoto, Kayoko Nonaka

{"title":"Unstable sitting postures affect head and neck muscle activity during mastication.","authors":"Motoyoshi Morishita, Mizuho Ohta, Nobuhiro Okamoto, Kayoko Nonaka","doi":"10.2334/josnusd.25-0366","DOIUrl":"https://doi.org/10.2334/josnusd.25-0366","url":null,"abstract":"Purpose: This study aimed to assess whether masseter, suprahyoid, and trapezius muscle activities during mastication differed with changes in sitting posture.Methods: Thirteen healthy young adults chewed gummy candies under three conditions: sitting with sole-ground contact, sitting without sole-ground contact, and sitting on an unstable balance board. Electromyographic electrodes were attached to the masseter, suprahyoid, and trapezius muscles to evaluate muscle activity. The examiner also evaluated the mastication time, total integral values for each muscle, and number of chewing cycles from start of mastication to swallowing.Results: The total integral values for masseter and suprahyoid muscles were significantly higher for the no sole-ground contact and balance-board conditions than those under the sole contact condition. The total integral value for the right trapezius muscle was also significantly greater for the no sole-ground contact and balance-board conditions than that under the sole contact condition.Conclusion: Increased masseter and suprahyoid muscle activity under unstable sitting conditions suggests that a stable sitting posture is necessary for efficient mastication. The right trapezius muscle also exhibited greater activity under unstable sitting conditions, which may have been a compensatory response to enhance postural stability alongside the masticatory muscles.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"68 2","pages":"112-117"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of ion implantation on adhesion to zirconia material. 离子注入对氧化锆材料粘附性能的影响。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0328

Takaaki Sato, Yoshikazu Teranishi, Yasushi Shimada, Masaomi Ikeda

{"title":"Effect of ion implantation on adhesion to zirconia material.","authors":"Takaaki Sato, Yoshikazu Teranishi, Yasushi Shimada, Masaomi Ikeda","doi":"10.2334/josnusd.25-0328","DOIUrl":"https://doi.org/10.2334/josnusd.25-0328","url":null,"abstract":"Purpose: This study was designed to investigate the effect of silicon (Si) ion implantation on the strength of zirconia bonding to resin cement.Methods: Si ions were implanted in a sintered zirconia plate at an acceleration energy of 50 or 100 keV. The implantation dose was divided into four subgroups of 1 × 1013, 1 × 1014, 1 × 1015, or 1 × 1016 ions/cm2. A total of nine groups were set up, including a control group. Stainless steel rods were bonded to the zirconia plates using resin cement and subjected to tensile bond strength testing. Other plates were subjected to surface roughness measurement and elemental analyses.Results: In the tensile bond strength test, some groups exhibited significantly higher values than the control group. The surface roughness measured using a confocal laser scanning microscope showed no significant differences in any group compared with the control group. The elemental analyses showed that X-ray photoelectron spectroscopy was able to detect Si ions that could not be detected by energy-dispersive X-ray spectroscopy.Conclusion: Despite the limitations of this study, it proved possible to implant Si ions into zirconia materials. It was also suggested that the strength of zirconia bonding to resin cement could be improved by irradiation.","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":"68 1","pages":"40-43"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report on the oral manifestations of Stüve-Wiedemann syndrome. st<s:1> ve- wiedemann综合征口腔表现1例报告。

IF 1.7 4区医学

Journal of oral science Pub Date : 2026-01-01 DOI: 10.2334/josnusd.25-0252

Ahammad Kandari, Wafaa Alshamali, Dalal ALnakkas, Hessa Alfadhli, Israa Alibraheem

引用次数: 0