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Erratum to 'Riboflavin deficiency is highly prevalent in women and children across high and low/middle income countries worldwide' [J. Nutr. 2026; 156: 101277]. 核黄素缺乏症在全球高收入和中低收入国家的妇女和儿童中非常普遍[J]。减轻。2026;156: 101277)。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-03-23 DOI: 10.1016/j.tjnut.2026.101487
Liadhan McAnena, Mary Ward, Adrian McCann, Kristina Pentieva, Leane Hoey, Ryan Barlow, Harry R Jarrett, Maeve A Kerr, J J Strain, Catherine Hughes, Albert Flynn, Janette Walton, Yvonne Lamers, Parveen Bhatti, Crystal D Karakochuk, Kyly C Whitfield, Michelle Murphy, Pere Cavallé-Busquets, Lorna J Cox, Ann Prentice, Damon A Parkington, Tabasum Makhdoomi, Sengchanh Kounnavong, Guy-Marino Hinnouho, Nelly Birungi, Tim J Green, Helene McNulty
{"title":"Erratum to 'Riboflavin deficiency is highly prevalent in women and children across high and low/middle income countries worldwide' [J. Nutr. 2026; 156: 101277].","authors":"Liadhan McAnena, Mary Ward, Adrian McCann, Kristina Pentieva, Leane Hoey, Ryan Barlow, Harry R Jarrett, Maeve A Kerr, J J Strain, Catherine Hughes, Albert Flynn, Janette Walton, Yvonne Lamers, Parveen Bhatti, Crystal D Karakochuk, Kyly C Whitfield, Michelle Murphy, Pere Cavallé-Busquets, Lorna J Cox, Ann Prentice, Damon A Parkington, Tabasum Makhdoomi, Sengchanh Kounnavong, Guy-Marino Hinnouho, Nelly Birungi, Tim J Green, Helene McNulty","doi":"10.1016/j.tjnut.2026.101487","DOIUrl":"10.1016/j.tjnut.2026.101487","url":null,"abstract":"","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101487"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Muscle Recovery and Myofibrillar Protein Synthesis after Damaging Exercise with Recombinant Bovine β-Lactoglobulin, Dairy-Derived Whey or Carbohydrate Supplementation in Young Healthy Adults. 重组牛β-乳球蛋白、乳源性乳清或碳水化合物对年轻健康成人损伤性运动后肌肉恢复和肌原纤维蛋白合成的影响
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-01-05 DOI: 10.1016/j.tjnut.2025.101321
Lucy M Rogers, Marie Korzepa, Archie E Belfield, Jonathan I Quinlan, Gareth A Wallis, Leigh Breen
{"title":"Muscle Recovery and Myofibrillar Protein Synthesis after Damaging Exercise with Recombinant Bovine β-Lactoglobulin, Dairy-Derived Whey or Carbohydrate Supplementation in Young Healthy Adults.","authors":"Lucy M Rogers, Marie Korzepa, Archie E Belfield, Jonathan I Quinlan, Gareth A Wallis, Leigh Breen","doi":"10.1016/j.tjnut.2025.101321","DOIUrl":"10.1016/j.tjnut.2025.101321","url":null,"abstract":"<p><strong>Background: </strong>Supplementation with recombinant bovine β-lactoglobulin (rBLG), a precision-engineered mimetic of dairy-derived whey, supports similar resistance exercise (RE) training-induced muscle remodeling to whey protein (WHEY). However, the influence of rBLG on recovery indices and muscle protein synthesis rates after damaging exercise is unknown.</p><p><strong>Objectives: </strong>To determine the influence of rBLG supplementation on indices of muscle recovery and integrated myofibrillar protein synthesis (iMyoPS) over 72 h following damaging RE, compared with WHEY and a carbohydrate placebo.</p><p><strong>Methods: </strong>In a randomized double-blind, placebo-controlled, parallel-group design, 27 healthy adults consuming a controlled diet (∼0.9 g/kg body mass/d of protein) were supplemented thrice daily with 0.3 g/kg body mass of rBLG, WHEY, or isocaloric carbohydrate placebo for 3 d following an acute bout of damaging lower-body RE (8 × 10 maximal, unilateral, eccentric knee extensions). Consumption of deuterated water combined with serial vastus lateralis muscle biopsies permitted the measurement of iMyoPS 72 h before (habitual) and after RE. Knee extensor maximum voluntary contraction (MVC), muscle soreness, and plasma concentrations of creatine kinase and lactate dehydrogenase (LDH) were also assessed post-RE to characterize muscle recovery.</p><p><strong>Results: </strong>iMyoPS fractional synthetic rate (%/d) increased following damaging RE (P < 0.001), with no significant differences between groups. Knee extensor MVC decreased, and subjective muscle soreness and plasma LDH concentrations increased following strenuous exercise (P < 0.05 for all) with no significant differences between groups.</p><p><strong>Conclusions: </strong>At habitual dietary protein intakes ∼0.9 g/kg body mass/d, further rBLG or WHEY supplementation did not influence muscle recovery or iMyoPS rates, suggesting that protein supplementation, at the intakes studied, may have limited efficacy as a tool to enhance muscle recovery and remodeling from damaging exercise.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101321"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to Editor: Associations of Fructose Consumption with Prevalence and Incidence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) - the Kuopio Ischaemic Heart Disease Risk Factor Study. 致编辑的信:果糖摄入与代谢功能障碍相关脂肪变性肝病(MASLD)的患病率和发病率的关联——库奥皮奥缺血性心脏病危险因素研究。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-02-25 DOI: 10.1016/j.tjnut.2026.101438
Johanna K DiStefano, Glenn S Gerhard
{"title":"Letter to Editor: Associations of Fructose Consumption with Prevalence and Incidence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) - the Kuopio Ischaemic Heart Disease Risk Factor Study.","authors":"Johanna K DiStefano, Glenn S Gerhard","doi":"10.1016/j.tjnut.2026.101438","DOIUrl":"10.1016/j.tjnut.2026.101438","url":null,"abstract":"","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101438"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Whey of the Future: Is rBLG a New Player within Protein Nutrition? 乳清的未来:rBLG是蛋白质营养领域的新玩家吗?
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-03-20 DOI: 10.1016/j.tjnut.2026.101485
Freyja Ad Haigh, Benjamin T Wall
{"title":"The Whey of the Future: Is rBLG a New Player within Protein Nutrition?","authors":"Freyja Ad Haigh, Benjamin T Wall","doi":"10.1016/j.tjnut.2026.101485","DOIUrl":"10.1016/j.tjnut.2026.101485","url":null,"abstract":"","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101485"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence Applications across the Spectrum of Malnutrition: From Undernutrition to Obesity. 人工智能在营养不良领域的应用:从营养不良到肥胖。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-04-27 DOI: 10.1016/j.tjnut.2026.101454
Elif Günalan, Gülser Tartıcı, Esra Aladağ, Özge Çonak
{"title":"Artificial Intelligence Applications across the Spectrum of Malnutrition: From Undernutrition to Obesity.","authors":"Elif Günalan, Gülser Tartıcı, Esra Aladağ, Özge Çonak","doi":"10.1016/j.tjnut.2026.101454","DOIUrl":"10.1016/j.tjnut.2026.101454","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is a significant global public health challenge, with rising prevalence and vital consequences. Recent advances in artificial intelligence (AI) have transformed approaches to understanding, monitoring, and managing these conditions. In this context, a multidimensional approach, integrating digital anthropometry and precision nutrition with image processing and AI-based mobile applications, has progressed in the field.</p><p><strong>Objectives: </strong>This study provides a comprehensive bibliometric and critical analysis of AI applications in malnutrition, including undernutrition and obesity.</p><p><strong>Methods: </strong>Using RStudio software (version 4.1.3) and the bibliometrix R package, 716 publications were identified in the Scopus database, of which 191 original research articles were analyzed. This context focuses on subfields such as digital anthropometry, precision nutrition, image processing technologies, and AI-supported mobile applications.</p><p><strong>Results: </strong>The findings highlight AI as a rapidly growing and interdisciplinary field of research. Engineering journals frequently publish cutting-edge studies, with the United States, China, Spain, and Korea leading in productivity and citations. Although diet, nutrition, and diabetes themes dominate the literature, undernutrition and obesity remain underrepresented.</p><p><strong>Conclusions: </strong>This study emphasizes the importance of transitioning the current fragmented research landscape into a standardized and ethically governed framework for the sustainable development of AI in nutrition. By bridging identified thematic imbalances and prioritizing scalable digital tools, AI can be repositioned as a strategic pillar of public health, rather than just a clinical instrument. Such a shift is essential for effectively addressing the global double burden of malnutrition and ensuring long-term, sustainable progress in the field.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101454"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Value Score Rates Foods Based on Nutrient Density and Noncommunicable Disease Prevention. 基于营养密度和非传染性疾病预防的食物营养价值评分。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-03-24 DOI: 10.1016/j.tjnut.2026.101443
Ty Beal, Flaminia Ortenzi
{"title":"Nutritional Value Score Rates Foods Based on Nutrient Density and Noncommunicable Disease Prevention.","authors":"Ty Beal, Flaminia Ortenzi","doi":"10.1016/j.tjnut.2026.101443","DOIUrl":"10.1016/j.tjnut.2026.101443","url":null,"abstract":"<p><strong>Background: </strong>Most nutrient profiling systems (NPS) were designed exclusively for high-income countries to address chronic-disease risk and do not capture locally available foods, nutrient bioavailability, or the dual burden of undernutrition and noncommunicable diseases in low- and middle-income countries (LMICs).</p><p><strong>Objectives: </strong>We developed and tested the Nutritional Value Score (NVS)-a novel NPS based on priority nutrients and dietary factors predictive of noncommunicable disease risk-to better identify foods with high nutritional value relevant to health priorities in high-income countries and LMICs alike, and to serve as a functional unit for environmental impact and affordability analyses.</p><p><strong>Methods: </strong>The NVS combines 7 weighted components-nutrient ratios (sodium:potassium, saturated:unsaturated fat, and carbohydrate:fiber), vitamins, minerals, protein (quality-adjusted), n-3 fatty acids, fiber, and Calories-scaled from 1 to 100, with a 25% penalty for ultraprocessed foods. It was applied to 289 commonly consumed foods in Indonesia, Bangladesh, Kenya, Nigeria, and the United States using local food composition data where available. We evaluated content validity, face validity, convergent and discriminant validity, and conducted various sensitivity analyses.</p><p><strong>Results: </strong>The NVS identified organ meats, dark green leafy vegetables, fish, and seafood as the highest-scoring foods and soft drinks, grain-based baked sweets, instant noodles, packaged ultraprocessed snacks, and refined grains as the lowest. It showed stronger discrimination within fruits, vegetables, animal-source foods, and starchy staples than Nutri-Score or Health Star Rating (HSR). Correlations were moderate overall with Nutri-Score (r = 0.58) and HSR (r = 0.63) but weak for ultraprocessed foods (r < 0.15). Rankings shifted notably when using mass-based compared with energy-based references units.</p><p><strong>Conclusions: </strong>The NVS better distinguishes foods with high nutritional value than popular existing NPS and supports more meaningful environmental impact and affordability comparisons than conventional mass-based or energy-based reference units. Although further criterion validation is needed, the NVS shows promise to guide policies and programs prioritizing nutritious foods globally.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101443"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147512817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adiposity Rebound or Fat-Free Mass Anabolism in Children-Challenging a 42-Year-Old BMI Puzzle with Waist-to-Height Ratio: The ASNF-NNF 2025 Inaugural Flemming Quaade Award for Innovation in Childhood Obesity Lecture. 儿童肥胖反弹或无脂质量合成代谢-挑战42年的腰高比BMI难题:美国营养基金会2025年首届弗莱明四重奏奖儿童肥胖创新讲座。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-05-01 Epub Date: 2026-03-10 DOI: 10.1016/j.tjnut.2026.101437
Andrew O Agbaje
{"title":"Adiposity Rebound or Fat-Free Mass Anabolism in Children-Challenging a 42-Year-Old BMI Puzzle with Waist-to-Height Ratio: The ASNF-NNF 2025 Inaugural Flemming Quaade Award for Innovation in Childhood Obesity Lecture.","authors":"Andrew O Agbaje","doi":"10.1016/j.tjnut.2026.101437","DOIUrl":"10.1016/j.tjnut.2026.101437","url":null,"abstract":"<p><strong>Background: </strong>Rolland-Cachera et al. introduced the concept of \"adiposity rebound\" in a paper published in the American Journal of Clinical Nutrition in 1984. They observed that body mass index (BMI) increased during the first year of life and then decreased with a renewed rise at about age 6 y, which they termed \"adiposity rebound,\" concluding that early rebound increased the risk of excess adiposity in later years. Although this concept has been vigorously criticized, an alternative explanation for this phenomenon has been lacking for 42 y. Moreover, BMI does not distinguish between fat mass and muscle mass.</p><p><strong>Objectives: </strong>To examine whether a more accurate surrogate measure of adiposity, waist circumference to height ratio (WHtR), confirms or refutes BMI-based adiposity rebound.</p><p><strong>Methods: </strong>In this study, 2410 children and adolescents' data aged 2-19 y from the US National Health and Nutrition Examination Survey 2021-2023 cycle were analyzed using a more accurate WHtR. Both raw values of BMI and WHtR and their z-scores were plotted to ascertain the trajectory of adiposity with increasing age.</p><p><strong>Results: </strong>The mean value of BMI at age 2 y (17.1 kg/m<sub>2</sub>) was regained by age 6 y (mean BMI 17.0 kg/m<sub>2</sub>), while the mean BMI at age 7 y was 17.3 kg/m<sub>2</sub> after a significant decrease (adiposity rebound). The WHtR mean value at age 2 y (0.54) was never regained throughout childhood and adolescence (0.51). Although BMI-adiposity rebound seems to be completed by age 6 y, WHtR, which specifically assesses fat mass, continued decreasing. A body composition reset (BCR) at the intersection of BMI and WHtR trajectories at age 4 y until WHtR nadir at age 7 y was observed. The BCR is a post-infancy BMI increase after an initial decline that simultaneously corresponds to a continued WHtR-adiposity physiologic decrease, culminating at the lowest WHtR trajectory before a subsequent WHtR increase.</p><p><strong>Conclusions: </strong>These novel findings establish that BMI-adiposity rebound is not physiologic but an epiphenomenon. I posit that \"adiposity rebound\" is a BMI-induced false discovery similar to the \"obesity paradox\" in adults. Therefore, fat-free mass or skeletal muscle mass anabolism is likely the accurate physiologic explanation for the BCR effect that occurs in early childhood.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101437"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147443950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in "Healthy" Food Consumption Overall and by Nova Food Processing Categories among US Adults from 2003 - March 2020. 2003年至2020年3月美国成年人“健康”食品消费总体趋势和新食品加工类别
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-04-29 DOI: 10.1016/j.tjnut.2026.101561
Anna C Tucker, Euridice Martínez-Steele, Laura E Caulfield, Casey M Rebholz, Julia A Wolfson
{"title":"Trends in \"Healthy\" Food Consumption Overall and by Nova Food Processing Categories among US Adults from 2003 - March 2020.","authors":"Anna C Tucker, Euridice Martínez-Steele, Laura E Caulfield, Casey M Rebholz, Julia A Wolfson","doi":"10.1016/j.tjnut.2026.101561","DOIUrl":"https://doi.org/10.1016/j.tjnut.2026.101561","url":null,"abstract":"<p><strong>Background: </strong>In 2024, the Food and Drug Administration (FDA) updated the \"healthy\" claim that can appear on foods and beverages. However, trends and demographic differences in intake of \"healthy\" foods, is unknown, and there is concern that ultra-processed foods (UPF) may qualify for the \"healthy\" claim.</p><p><strong>Objectives: </strong>To examine trends in \"healthy\" food intake by Nova food processing category among US adults, overall and across demographic groups.</p><p><strong>Methods: </strong>Using a serial cross-sectional design, we examined dietary intake among a nationally representative sample of US adults (>20 years) with two valid 24-hour dietary recalls from the National Health and Nutrition Examination Survey (NHANES) (2003-2004 - 2017-March 2020; n=34,164). We examined trends in FDA-aligned (i.e., foods meeting \"healthy\" criteria) and FDA-unaligned (i.e., foods not meeting \"healthy\" criteria) intake as a proportion of total energy, overall and by Nova category. We used generalized linear models adjusted for demographic characteristics, and examined differences using stratified models.</p><p><strong>Results: </strong>FDA-aligned intake increased from 9.7% to 10.7% (p-trend=0.03). FDA-aligned minimally processed food (MPF) intake did not change (p-trend=0.36), but FDA-unaligned MPF intake decreased (p-trend<0.001). FDA-aligned UPF intake increased but comprised <2% of energy intake. Intake of FDA-unaligned UPFs also increased (p-trend<0.01) and comprising the majority of energy intake (>51%) in all years. Intake of \"healthy\" UPFs differed by age, race and ethnicity, and education.</p><p><strong>Conclusions: </strong>Intake of \"healthy\" foods and beverages increased, but comprised <12% of energy intake in all years. FDA-unaligned UPFs, not \"healthy\" foods, formed the foundation of US adults' dietary intakes, regardless of demographic group.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101561"},"PeriodicalIF":3.8,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel elemental nano-selenium improves growth performance and meat quality with potentially regulating muscle energy metabolism via the AMPK-mTOR signaling in finishing pigs. 一种新型元素纳米硒可以通过AMPK-mTOR信号通路调节肥育猪的肌肉能量代谢,从而改善猪的生长性能和肉质。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-04-28 DOI: 10.1016/j.tjnut.2026.101555
Wei-Cai Luo, Rong-Hui Huang, Meng Liu, Jia-Cheng Yang, Yu-Wei Zhao, Gang Zuo, Yuan-Zhi Cheng, Zhang-Chao Deng, Lv-Hui Sun
{"title":"A novel elemental nano-selenium improves growth performance and meat quality with potentially regulating muscle energy metabolism via the AMPK-mTOR signaling in finishing pigs.","authors":"Wei-Cai Luo, Rong-Hui Huang, Meng Liu, Jia-Cheng Yang, Yu-Wei Zhao, Gang Zuo, Yuan-Zhi Cheng, Zhang-Chao Deng, Lv-Hui Sun","doi":"10.1016/j.tjnut.2026.101555","DOIUrl":"https://doi.org/10.1016/j.tjnut.2026.101555","url":null,"abstract":"<p><strong>Background: </strong>Selenium (Se) is a vital trace element affecting muscle development and quality.</p><p><strong>Objectives: </strong>This study aimed to evaluate the effects of sodium selenite (SeNa), selenomethionine (SeMet), and elemental nano-selenium (SeNPs) on growth performance and meat quality and the underlying mechanisms in finishing pigs.</p><p><strong>Methods: </strong>Finishing pigs (120 pigs/group) were fed with basal diet (CON, 0.108 mg Se/kg) or CON supplemented with 0.4 mg Se/kg SeNa, SeMet, or SeNPs. At week 6, longissimus dorsi (LD) muscle was collected for meat quality, selenium, redox status, metabolomics and transcriptomics analysis.</p><p><strong>Results: </strong>Compared with the CON, the 3 forms of Se supplementation increased (P < 0.05) body weight gain (1.84-6.07%) and reduced (P < 0.05) the feed/gain ratio (2.72-4.89%) of pigs. Feed intake (0.97%) increased (P < 0.05) in the SeNPs group but no significant changed was observed in the SeNa and SeMet groups. And SeNPs further improved (P < 0.05) these performances by 1.65-4.16% compared with SeNa. Moreover, SeNPs and SeMet enhanced (P < 0.05) Se concentration, marbling and color, but decreased (P < 0.05) drip loss in the LD muscle than those of CON and SeNa. Notably, SeNPs uniquely stabilized postmortem pH<sub>45 min</sub> and pH<sub>24 h</sub> and minimized drip loss than the other 3 groups. Additionally, SeMet and(or) SeNPs increased (P < 0.05) triglyceride (TG) contents and the activities of glutathione peroxidase (GPX) and thioredoxin reductase (TXNRD) in LD muscle. Metabolomic and transcriptomic profiling showed that SeNPs reduced lipid metabolic related pathways and associated with coordinated regulation of muscle and adipose tissue development. Multi-omics integration further identified the AMPK-mTOR signaling pathway as a central regulatory network targeted by SeNPs, thereby contributing to improvements in growth performance and meat quality in finishing pigs.</p><p><strong>Conclusions: </strong>Compared with SeNa or SeMet, SeNPs demonstrated a unique ability to improve growth performance, meat quality and antioxidant status in finishing pigs, associated with regulation energy metabolism by activating the AMPK-mTOR regulatory network.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101555"},"PeriodicalIF":3.8,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infant intake of non-lactose carbohydrates in milk feeding is associated with lower diet quality scores for dairy and protein from ages 13-72 months. 婴儿在母乳喂养中摄入非乳糖碳水化合物与13-72个月大的乳制品和蛋白质饮食质量得分较低有关。
IF 3.8 3区 医学
Journal of Nutrition Pub Date : 2026-04-28 DOI: 10.1016/j.tjnut.2026.101556
Christopher E Anderson, Lorrene D Ritchie, Shannon E Whaley, M Pia Chaparro
{"title":"Infant intake of non-lactose carbohydrates in milk feeding is associated with lower diet quality scores for dairy and protein from ages 13-72 months.","authors":"Christopher E Anderson, Lorrene D Ritchie, Shannon E Whaley, M Pia Chaparro","doi":"10.1016/j.tjnut.2026.101556","DOIUrl":"https://doi.org/10.1016/j.tjnut.2026.101556","url":null,"abstract":"<p><strong>Background: </strong>Infant receipt of milk products with added non-lactose carbohydrates, primarily infant formula, is highly prevalent. This study was conducted to assess relationships between infant receipt of milk products with added non-lactose carbohydrates and subsequent child diet quality.</p><p><strong>Methods: </strong>Data from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) Infant and Toddler Feeding Practices Study (ITFPS)-2, a national cohort study of infants born into WIC in 2013-2014 (n=1,379), were used. Child diet was assessed with twenty-four hour dietary recalls. Intake of milk products with added non-lactose carbohydrates was determined from recalls at ages 1 and/or 3, 5, 7, 9, and 11 months (continuous: percent of milk). Differences in subsequent Healthy Eating Index (HEI)-2020 Toddler (ages 13, 15, 18 months) and HEI-2020 (ages 2, 3, 4, 5, 6 years) scores (total, individual components) were assessed using multivariable mixed effects regression models.</p><p><strong>Results: </strong>Each additional 25% of infant milk product intake containing added non-lactose carbohydrates was associated with significantly lower dairy intake scores at ages 1 (difference [95% confidence interval]: -0.12 [-0.20, -0.04]), 5 (-0.20 [-0.33, -0.08]), and 6 years (-0.24 points [-0.38, -0.11]); lower total protein score at 1 year (-0.05 [-0.09, <0.00]); higher fatty acid ratio score at 1 (0.13 [0.03, 0.23]) and 2 years (0.17 [0.02, 0.32]); and with higher saturated fat score at 1 year (0.12 [0.03, 0.22]).</p><p><strong>Conclusions: </strong>Future research into whether caregiver-perceived lactose-sensitivity contributes to lower dairy intake in childhood among infants who consumed milk with added non-lactose carbohydrates in infancy is necessary.</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":"101556"},"PeriodicalIF":3.8,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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