Journal of oral biology and craniofacial research最新文献

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Hyaluronic acid versus amniotic membrane in wound healing and bone regeneration in extraction sockets - A randomized controlled trial 透明质酸与羊膜在拔牙窝伤口愈合和骨再生中的作用——一项随机对照试验
Journal of oral biology and craniofacial research Pub Date : 2025-02-11 DOI: 10.1016/j.jobcr.2025.01.027
Abinav Sundar T. , Pratiksha Shetty , Padmaraj Hegde , Shreya S.
{"title":"Hyaluronic acid versus amniotic membrane in wound healing and bone regeneration in extraction sockets - A randomized controlled trial","authors":"Abinav Sundar T. ,&nbsp;Pratiksha Shetty ,&nbsp;Padmaraj Hegde ,&nbsp;Shreya S.","doi":"10.1016/j.jobcr.2025.01.027","DOIUrl":"10.1016/j.jobcr.2025.01.027","url":null,"abstract":"<div><h3>Background</h3><div>Surgical removal of the impacted third molar is a routinely employed procedure in oral surgery, often associated with various complications which affect wound healing. Hyaluronic acid (HA) and freeze-dried (lyophilized) amniotic membrane (AM) have demonstrated the potential to promote wound healing and bone regeneration. These could aid in the healing of the extraction socket post-disimpaction.</div></div><div><h3>Objectives</h3><div>To assess the extent of wound healing and bone regeneration in extraction sockets of surgically removed mandibular third molars following intra-socket application of 0.2 % HA gel and 2.5 × 2.5 cm of AM.</div></div><div><h3>Material and methods</h3><div>45 patients were clinically and radiographically evaluated based on the inclusion and exclusion criteria and were randomized by lottery method into three groups – Group 1, control, Group 2, AM, and Group 3, HA. The pain scores were evaluated using the visual analog scale. The extent of facial swelling, trismus and bone regeneration were assessed at three different time intervals.</div></div><div><h3>Results</h3><div>A significant difference (<em>p</em>&lt;0.05) in the pain score was observed between the control group and the study groups. The extent of facial swelling and trismus observed was of significance within the groups (<em>p</em>&lt;0.05). Group 2 exhibited significantly improved levels of trabecular bone formation at the third post-operative month (<em>p</em>&lt;0.05).</div></div><div><h3>Conclusion</h3><div>HA and AM could be potentially useful in improving the post-operative sequelae following surgical removal of mandibular third molars in terms of pain, wound healing, and overall bone regeneration.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 305-309"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative efficacy of LLLT and LED therapy on osteoblast proliferation and osteoclast suppression: An in vitro co-culture study LLLT和LED治疗对成骨细胞增殖和破骨细胞抑制的比较疗效:体外共培养研究
Journal of oral biology and craniofacial research Pub Date : 2025-02-11 DOI: 10.1016/j.jobcr.2025.01.018
Dr Divyabharathi Selvam, Dr Venkat Rengasamy
{"title":"Comparative efficacy of LLLT and LED therapy on osteoblast proliferation and osteoclast suppression: An in vitro co-culture study","authors":"Dr Divyabharathi Selvam,&nbsp;Dr Venkat Rengasamy","doi":"10.1016/j.jobcr.2025.01.018","DOIUrl":"10.1016/j.jobcr.2025.01.018","url":null,"abstract":"<div><h3>Background</h3><div>Dental implants are a reliable solution for tooth loss, but challenges remain regarding osseointegration and complications. Photobiomodulation therapy (PBMT), including Low-Level Laser Therapy (LLLT) and Light Emitting Diode (LED) therapy, has shown potential in enhancing bone healing. However, comparative studies on their effects on osteoblasts and osteoclasts are limited.</div></div><div><h3>Aim</h3><div>To compare the effects of LLLT and LED therapy on osteoblast proliferation and osteoclast suppression in an in vitro co-culture model.</div></div><div><h3>Materials and methods</h3><div>MG-63 osteoblast-like cells and RAW 264.7 osteoclasts were co-cultured on titanium discs. Discs were treated with LLLT (940 nm, 50 mW) or LED (660 nm, 89 mW) for different durations. Osteoblast proliferation was measured by MTT assay, and osteoclast activity was evaluated using TRAP staining and resorption pit analysis.</div></div><div><h3>Results</h3><div>LED therapy significantly enhanced osteoblast proliferation and suppressed osteoclast activity more effectively than LLLT. Optimal results were observed with a 6-min LED exposure.</div></div><div><h3>Conclusion</h3><div>LED therapy shows greater potential than LLLT for promoting osteoblast proliferation and suppressing osteoclast activity, indicating its clinical value for improving bone regeneration and implant integration.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 325-330"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of age, sex, and presence of cleft lip and palate on the quantity and quality of saliva-derived DNA 年龄、性别和唇腭裂对唾液来源DNA数量和质量的影响
Journal of oral biology and craniofacial research Pub Date : 2025-02-10 DOI: 10.1016/j.jobcr.2025.01.030
Lina M. Escobar , Zita Bendahan , Deisy Abril , David Díaz-Baez , Adolfo Paternina , Farith González-Martinez , Ma Clara González-Carrera
{"title":"Influence of age, sex, and presence of cleft lip and palate on the quantity and quality of saliva-derived DNA","authors":"Lina M. Escobar ,&nbsp;Zita Bendahan ,&nbsp;Deisy Abril ,&nbsp;David Díaz-Baez ,&nbsp;Adolfo Paternina ,&nbsp;Farith González-Martinez ,&nbsp;Ma Clara González-Carrera","doi":"10.1016/j.jobcr.2025.01.030","DOIUrl":"10.1016/j.jobcr.2025.01.030","url":null,"abstract":"<div><div>The quantity and quality of DNA are crucial factors in determining polymorphisms in samples from individuals with and without pathologies such as cleft lip and palate (CL/P). Saliva is increasingly being evaluated as a collection method. This study aimed to compare saliva DNA concentrations from individuals of different ages with and without CL/P.</div><div>Saliva samples were collected, DNA was extracted and the quantification was performed by spectrophotometry. Kruskal-Wallis test was used to compare frequencies between groups, and Spearman's rho for correlations.</div><div>We obtained saliva DNA from 314 individuals: 107 with CL/P (mean age: 12.7 ± 6.5 years), 103 parents of children with CL/P (mean age: 41.1 ± 9.3 years), 52 individuals without CL/P under 18 years old (controls), and 52 individuals without CL/P over 18 years old (controls). The sample comprised 32.2 % females and 67.8 % males.</div><div>Statistically significant differences in DNA concentrations were found between individuals under and over 18 years old (12.38 and 21.3 ng/μl, respectively, p = 0.0001), but no differences were observed between males and females. Individuals with CL/P had lower DNA concentrations (12.45 ng/μl) compared to their parents and controls (21.95 and 21.15 ng/μl, respectively). Our results showed a direct correlation between age and DNA concentration in individuals with CL/P under 18 years old (R = 0.328).</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 246-249"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143376864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxidative alterations in exfoliated oral mucosa cells of patients with major depressive disorder 重度抑郁症患者脱落口腔黏膜细胞的氧化改变
Journal of oral biology and craniofacial research Pub Date : 2025-02-10 DOI: 10.1016/j.jobcr.2025.01.026
Lukas Mendes de Abreu , Cintia Rodrigues da Silva , Ana Laura Ferreira Bortoleto , Giovana Barros Nunes , Matheus Martins Gracia , Rafael Akira Tzanno Murayama , Daniel Galera Bernabé , Gisele Zoccal Mingoti
{"title":"Oxidative alterations in exfoliated oral mucosa cells of patients with major depressive disorder","authors":"Lukas Mendes de Abreu ,&nbsp;Cintia Rodrigues da Silva ,&nbsp;Ana Laura Ferreira Bortoleto ,&nbsp;Giovana Barros Nunes ,&nbsp;Matheus Martins Gracia ,&nbsp;Rafael Akira Tzanno Murayama ,&nbsp;Daniel Galera Bernabé ,&nbsp;Gisele Zoccal Mingoti","doi":"10.1016/j.jobcr.2025.01.026","DOIUrl":"10.1016/j.jobcr.2025.01.026","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate oxidative stress markers in the oral mucosal cells of individuals diagnosed with major depressive disorder (MDD).</div></div><div><h3>Methods</h3><div>A case-control design was used, including twenty patients diagnosed with MDD, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, and twenty healthy controls. Oral exfoliated cells were collected from all participants. Intracellular levels of reactive oxygen species (ROS), mitochondrial membrane potential (ΔΨm), caspase-3 and -7 activity, and reduced glutathione (GSH) were measured in Arbitrary Fluorescence Units (AFU).</div></div><div><h3>Results</h3><div>The MDD group demonstrated significantly elevated intracellular ROS levels (p = 0.0012) and caspase-3 and -7 activity (p = 0.0171) in comparison to the control group. Additionally, a decrease in ΔΨm expression was observed in the oral cells of MDD patients (p = 0.0265), whereas GSH expression levels did not differ significantly between the two groups (p = 0.8908).</div></div><div><h3>Conclusions</h3><div>The findings indicate heightened oxidative stress in the oral exfoliated cells of individuals with MDD. This study supports the potential use of oral cells as a non-invasive biomarker source for assessing oxidative stress in depressive disorders.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 256-261"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the cost-effectiveness of prosthetic rehabilitation for partially edentulous teeth in India: A comparative study of Clasp-Retained RPDs, Thermoplastic Resin RPDs, and Cast Partial Dentures 评估印度部分无牙义齿修复的成本效益:卡环固位rpd、热塑性树脂rpd和铸造局部义齿的比较研究
Journal of oral biology and craniofacial research Pub Date : 2025-02-10 DOI: 10.1016/j.jobcr.2025.01.014
Subhash V , Aswini Kumar K , Vineetha Karuveettil
{"title":"Evaluating the cost-effectiveness of prosthetic rehabilitation for partially edentulous teeth in India: A comparative study of Clasp-Retained RPDs, Thermoplastic Resin RPDs, and Cast Partial Dentures","authors":"Subhash V ,&nbsp;Aswini Kumar K ,&nbsp;Vineetha Karuveettil","doi":"10.1016/j.jobcr.2025.01.014","DOIUrl":"10.1016/j.jobcr.2025.01.014","url":null,"abstract":"<div><h3>Background</h3><div>With rising life expectancy, partial edentulism has increased, particularly in developing nations where economic constraints, limited awareness, and inadequate dental care exacerbate the burden on aging populations. Patients with fewer than 20 teeth often experience a reduction in Oral Health-Related Quality of Life (OHRQoL), emphasizing the need for effective tooth replacement. Removable partial dentures (RPDs) are versatile, cost-effective solutions for partial tooth loss, including metal clasp-retained RPDs (MC-RPDs), thermoplastic resin RPDs (TR-RPDs), and cast partial dentures (CPDs).</div></div><div><h3>Methods</h3><div>This study evaluates the oral health-related quality of life, patient satisfaction, and cost-effectiveness of these three RPD types. A cross-sectional study was conducted with 42 participants, divided into three groups: MC-RPD, TR-RPD, and CPD, each with 14 patients. The Oral Health Impact Profile (OHIP-14) and Satisfaction Questionnaire (SAT) were administered at baseline and three months post-denture delivery. The study adhered to Consolidated Health Economic Evaluation Reporting Standards.</div></div><div><h3>Results</h3><div>Results showed significant differences in OHIP scores between the groups, with CPD offering the highest quality of life, followed by TR-RPD, and MC-RPD. Post-treatment, the mean OHIP scores for MC-RPD, TR-RPD, and CPD were 30.57 ± 4.09, 20.71 ± 4.03, and 22.36 ± 2.92, respectively, with CPD showing the greatest improvement. Patient satisfaction was highest for CPD, followed by TR-RPD, and least for MC-RPD. However, satisfaction differences between the groups were not statistically significant after three months.</div></div><div><h3>Conclusion</h3><div>This study highlights the superior performance of CPDs in enhancing OHRQoL and patient satisfaction, though their higher cost may limit accessibility. These findings provide valuable insights for dental practitioners and patients in selecting the most suitable and cost-effective RPD treatment options.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 240-245"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143376991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finite element stress analysis to evaluate and compare the effect of splinting in periodontally compromised teeth having 55 % bone loss with different materials 有限元应力分析评价和比较不同材料夹板对骨质流失55%牙周受损牙的效果
Journal of oral biology and craniofacial research Pub Date : 2025-02-10 DOI: 10.1016/j.jobcr.2025.01.011
Shivangi Joshi, Prakash Talreja, Prajakta Rao, Nilesh Joshi, Vinayak Thorat, Ruhi Mohta
{"title":"Finite element stress analysis to evaluate and compare the effect of splinting in periodontally compromised teeth having 55 % bone loss with different materials","authors":"Shivangi Joshi,&nbsp;Prakash Talreja,&nbsp;Prajakta Rao,&nbsp;Nilesh Joshi,&nbsp;Vinayak Thorat,&nbsp;Ruhi Mohta","doi":"10.1016/j.jobcr.2025.01.011","DOIUrl":"10.1016/j.jobcr.2025.01.011","url":null,"abstract":"<div><h3>Background</h3><div>Splinting is commonly employed to stabilize periodontally compromised teeth, but the choice of splint material significantly influences stress distribution within the periodontal ligament (PDL) and surrounding bone. This study aimed to evaluate and compare the stress distribution of four different splint materials—composite, fiber-reinforced composite (FRC), polyetheretherketone (PEEK), and metal—on mandibular anterior teeth with 55 % bone loss using finite element analysis (FEA).</div></div><div><h3>Methodology</h3><div>Finite element models of mandibular anterior teeth with 55 % bone loss were developed using SOLIDWORKS 2020. Simulations were conducted for non-splinted teeth and for teeth splinted with composite, FRC, PEEK, and metal. Stress analysis was performed in ANSYS software under vertical (100N at 0°) and oblique (100N at 45°) loading conditions. Von Mises stress values in the PDL and cortical bone were recorded and statistically analyzed using MedCalc software to compare the performance of different splint materials.</div></div><div><h3>Results</h3><div>Non-splinted teeth exhibited the highest stress levels, particularly under oblique loading conditions. Among the splinting materials, FRC showed the most effective reduction in stress across all teeth, especially under vertical loads. Composite and metal wire splints provided moderate stress reduction, with performance varying depending on the load angle. PEEK splints demonstrated good stress reduction under vertical loads but showed increased stress levels under oblique forces. These results underscore the influence of splint material and load direction on stress distribution in periodontally compromised teeth.</div></div><div><h3>Conclusion</h3><div>The study highlights the critical role of splint material in reducing stress on the PDL of periodontally compromised teeth. FRC splints emerged as the most effective material for minimizing stress under both vertical and oblique loading conditions. Composite and metal wire splints offered moderate efficacy, while PEEK splints were less effective under oblique loads. These findings provide valuable insights for clinicians in selecting optimal splint materials for periodontal stabilization.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 250-255"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of upper airway airflow dynamics in young adults with isolated Robin sequence: An exploratory investigation 分离Robin序列的年轻成人上呼吸道气流动力学特征:一项探索性调查
Journal of oral biology and craniofacial research Pub Date : 2025-02-10 DOI: 10.1016/j.jobcr.2025.01.009
Maria Noel Marzano-Rodrigues , Sergio Henrique Kiemle Trindade , Ivy Kiemle Trindade-Suedam
{"title":"Characterization of upper airway airflow dynamics in young adults with isolated Robin sequence: An exploratory investigation","authors":"Maria Noel Marzano-Rodrigues ,&nbsp;Sergio Henrique Kiemle Trindade ,&nbsp;Ivy Kiemle Trindade-Suedam","doi":"10.1016/j.jobcr.2025.01.009","DOIUrl":"10.1016/j.jobcr.2025.01.009","url":null,"abstract":"<div><div>Impaired upper airway dimension in adults with Isolated Robin Sequence (IRS) can alter airflow dynamics, increasing the risk of pharyngeal collapse and the onset of obstructive sleep apnea. This study aimed to characterize the upper airways of six young adults (20.83 ± 6.40 years) with IRS, using computational fluid dynamics. Upper airways of six patients were reconstructed using 3D segmentation, generating unstructured hybrid meshes with ≥4 million tetrahedral elements. Flow simulations at 15 l/min were solved using the realizable k-ε model and the finite volume method. Morphophysiological variables assessed were: total airway volumes, minimal cross-sectional areas, average pressure, velocity magnitude, wall shear stress, turbulent kinetic energy (k) production, and resistance. Airway volume corresponded to 29.32 ± 4.65 cm³ and minimal cross-sectional area was 1.00 ± 0.55 cm<sup>2</sup>. Pressure drop, airway resistance to airflow, velocity of the airflow and turbulent kinetic energy corresponded to 31.341 ± 15.837 Pa, 0.125 ± 0.063 (Pa s/ml), 1.882 ± 0.514 (m/s) and 0.152 ± 0.056 (m2/s2). The total airway volume exhibited a strong negative correlation with airway resistance (−0.899) and the inlet-to-outlet pressure drop (−0.899). The minimal cross-sectional area of the pharynx at the retroglossal level showed a strong negative correlation (−0.912) with the area-weighted average velocity magnitude of the airflow and with k production (−0.924). In conclusion, airway volume reduction and retroglossal obstruction in young adults with IRS are associated with altered fluid flow characteristics, including increased velocity magnitude, pressure drop, resistance, and turbulent kinetic energy production. These changes may increase the effort to breathe and predispose patients to sleep-disordered breathing.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 234-239"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143376990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the role of inflammatory biomarkers as a diagnostic tool in peri-implantitis 评估炎症生物标志物作为种植体周围炎诊断工具的作用
Journal of oral biology and craniofacial research Pub Date : 2025-02-09 DOI: 10.1016/j.jobcr.2025.01.015
Ayan Saxena , Pavitra Kumar Rastogi , Nand Lal , Umesh Pratap Verma , Rameshwari Singhal , Md. Kaleem Ahmad
{"title":"Evaluating the role of inflammatory biomarkers as a diagnostic tool in peri-implantitis","authors":"Ayan Saxena ,&nbsp;Pavitra Kumar Rastogi ,&nbsp;Nand Lal ,&nbsp;Umesh Pratap Verma ,&nbsp;Rameshwari Singhal ,&nbsp;Md. Kaleem Ahmad","doi":"10.1016/j.jobcr.2025.01.015","DOIUrl":"10.1016/j.jobcr.2025.01.015","url":null,"abstract":"<div><h3>Background</h3><div>Most studies have analyzed the presence of cytokines in Gingival crevicular fluid (GCF) in different periodontal diseases, but very limited studies have been conducted on Peri-implant crevicular fluid (PICF) in peri-implantitis.</div></div><div><h3>Aim</h3><div>The present study was conceptualized to explore the levels of Interleukin (IL)-1β and Interleukin (IL)-6 as a diagnostic marker in peri-implantitis.</div></div><div><h3>Materials and methods</h3><div>A total of 40 patients each having at least one dental implant were enrolled in the study. Clinical parameters were recorded around each implant and tooth nearest to it. Gingival crevicular fluid (GCF)/Peri-implant crevicular fluid (PICF) was collected to evaluate the concentration of IL‐1β and IL‐6. Conservative treatment was performed in peri-implantitis cases, 3 months after treatment their clinical parameters, IL-1β and IL-6 levels were recorded and compared with their pre-treatment values.</div></div><div><h3>Results</h3><div>Clinical parameters like Modified Plaque Index (MPI), Modified Bleeding Index (MBI) and Probing Pocket Depth (PPD) were statistically significantly higher in the peri-implantitis group as compared to the healthy implant group and healthy teeth group. IL-1β and IL-6 levels were also statistically significantly higher in the peri-implantitis group in comparison to healthy implants and healthy teeth group.</div></div><div><h3>Conclusion</h3><div>The study concludes that biomarkers in PICF can be used as a diagnostic tool to supplement the diagnosis of peri-implantitis along with the use of clinical parameters to make an early diagnosis of peri-implantitis possible.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 228-233"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of cryotherapy, laser therapy and intraligamentary dexamethasone injection on post-treatment pain after single visit RCT–A double-blinded, randomized placebo-controlled trial 冷冻治疗、激光治疗和韧带内注射地塞米松对单次访视后疼痛的影响
Journal of oral biology and craniofacial research Pub Date : 2025-02-09 DOI: 10.1016/j.jobcr.2025.01.005
Dr Sana Fatima , Dr Sonali Taneja , Dr Vivek Aggarwal , Dr Akriti Dheer , Dr Punya Taneja
{"title":"Effect of cryotherapy, laser therapy and intraligamentary dexamethasone injection on post-treatment pain after single visit RCT–A double-blinded, randomized placebo-controlled trial","authors":"Dr Sana Fatima ,&nbsp;Dr Sonali Taneja ,&nbsp;Dr Vivek Aggarwal ,&nbsp;Dr Akriti Dheer ,&nbsp;Dr Punya Taneja","doi":"10.1016/j.jobcr.2025.01.005","DOIUrl":"10.1016/j.jobcr.2025.01.005","url":null,"abstract":"<div><h3>Aim</h3><div>This study designed to evaluate the effect of adjuvant therapies on the intensity of post-treatment pain after single-visit RCT in molars with symptomatic apical periodontitis.</div></div><div><h3>Method</h3><div>ology: This trial was reported according PRIRATE 2020 guidelines and registered with CTRI/2019/03/018,153.100 patients diagnosed with symptomatic apical periodontitis with a preoperative pain allocated to 4 groups,Group-1: placebo,Group-2:Intraligamentary injection of dexamethasone, Group-3:cryotherapy, Group-4: laser therapy. Patients were instructed to record postoperative pain intensity and intake of analgesics after 6,12,24,48 &amp; 72 h. Intergroup pain intensity was tested by using the Kruskal-Wallis test. The need for painkillers between groups was analyzed using Chi-square test. P value of &lt;0.05 was considered statistically significant.</div><div>R<strong>esults</strong>: Patients in the placebo group exhibited higher intensity. Group 3 showed lesser pain at all-time intervals.</div></div><div><h3>Conclusion</h3><div>All the adjuvant pain management therapies reduced the intensity of postoperative pain and the frequency of intake of analgesics.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"15 2","pages":"Pages 221-227"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced deep learning techniques for recognition of dental implants 牙种植体识别的先进深度学习技术
Journal of oral biology and craniofacial research Pub Date : 2025-02-08 DOI: 10.1016/j.jobcr.2025.01.016
Veena Benakatti , Ramesh P. Nayakar , Mallikarjun Anandhalli , Rohit sukhasare
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