Journal of Obstetrics and Gynaecology Research最新文献

{"title":"Current medical support for victims of domestic violence and sexual assault: A nationwide survey among obstetricians and gynecologists in Japan","authors":"Yoshie Kono,&nbsp;Haruyo Atsumi,&nbsp;Kyoko Tanebe,&nbsp;Tomoko Adachi,&nbsp;Satoru Kyo","doi":"10.1111/jog.16272","DOIUrl":"10.1111/jog.16272","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>In 2018, one-stop support centers for victims of sexual crime and violence were established across Japan. Despite this initiative, recent findings suggest inadequate medical response methods for victims of sexual violence. This study conducted a nationwide survey to assess the current state of medical support available to such victims.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A survey was conducted via e-mail on 16,500 obstetricians and gynecologists from December 10, 2022, to January 20, 2023. A total of 1387 responses were received (response rate: 8.4%), and 1158 valid responses (valid response rate: 7.0%) were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the respondents, 76.5% reported examining patients suspected of being victims of domestic or sexual violence, with 90.5% recognizing the definition of sexual violence and 73.8% aware of the one-stop support centers. However, only 42.3%, 25.9%, and 19.6% had opportunities to learn about sexual violence against children, men, and sexual minorities, respectively. The most common learning opportunity was attending academic lectures on sexual violence. The actual examination rates for cases involving sexual violence against children, men, and sexual minorities were 26.5%, 1.6%, and 1.8%, respectively. Physicians who learned about sexual violence against children, men, and sexual minorities were significantly more likely to have experience in examining each case (<i>p</i> &lt; 0.001, <i>p</i> &lt; 0.01, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Despite their critical role, obstetricians and gynecologists in Japan have limited opportunities to learn about and support victims of domestic or sexual violence. Urgent actions are needed to ensure timely medical care, establish collaborative practices, and develop systematic protocols nationwide.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing aesthetic outcomes in primary umbilical endometriosis: Novel four-flap neoumbilicoplasty with case insights and comprehensive literature review","authors":"A. M. Suhas,&nbsp;S. Girija,&nbsp;I. Sabina,&nbsp;A. P. Manjunath","doi":"10.1111/jog.16271","DOIUrl":"10.1111/jog.16271","url":null,"abstract":"<p>Primary umbilical endometriosis (PUE) is a rare form of extragenital endometriosis, accounting for only 0.5%–1% of all endometriosis cases. Surgical excision is the primary treatment; however, it often results in disfigurement of the umbilicus, leading to aesthetic dissatisfaction. This case report aims to describe and discuss a simple surgical technique for aesthetically managing PUE. Our patient was a 35-year-old woman who presented with pain and bleeding from the umbilicus during menstruation. She denied any prior surgeries. Clinical examination and imaging revealed a small nodule within the umbilicus. The novel four-flap neoumbilicoplasty technique was employed, combining lesion removal and reconstruction in a single procedure, to achieve a high-quality aesthetic outcome. This technique is easily adoptable by general gynecologists, without advanced expertise or equipment. Its wider adoption could enhance surgical practice globally and build robust evidence in managing PUE.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in managing atypical glandular cells in cervical smears: Insights from real-world data and clinicians' perspectives","authors":"Mika Mizuno,&nbsp;Mai Nakazono,&nbsp;Nozomi Furuzono,&nbsp;Yusuke Kobayashi,&nbsp;Mika Fukuda,&nbsp;Shinichi Togami,&nbsp;Hiroaki Kobayashi","doi":"10.1111/jog.16269","DOIUrl":"https://doi.org/10.1111/jog.16269","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study evaluates clinicopathological outcomes and clinicians' awareness regarding the management of atypical glandular cells (AGC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We analyzed 98 AGC cases, excluding known endometrial cancer, from 238 initial cases, with a median age of 42 years (range 20–82). Cytological findings, including NOS and FN subcategories, diagnostic tests, treatments, and outcomes were evaluated. A survey on AGC awareness and practices was conducted among 134 obstetrician-gynecologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 98 cases (AGC-FN: 19.8%, AGC-NOS: 13.2%, unspecified: 67.3%), 44.9% initially showed no neoplasia; this dropped to 38.8% following up, identifying 11 additional AIS or cervical adenocarcinomas. Overall, 28.5% had AIS or more, 18% had CIN, and 13.3% had other malignancies, indicating some over/underdiagnosis. HPV testing in 79 cases showed a 48.1% positivity rate, including 14 type-18 and 12 type-16 cases. Among clinicians surveyed, 25% were aware of AGC subcategories, and only 11.9% were well-versed. Approximately 65% associated AGC with malignancy or precancerous lesions, and 52.6% used multiple diagnostic methods simultaneously. Even in the absence of neoplasia, 80% continued cytological examinations every 3–4 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study underscores the challenges in AGC management, highlighting the importance of follow-up and collaboration between clinicians and cytopathologists to detect significant lesions. It also emphasizes the need for providing learning opportunities for clinicians to address over/undertreatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral venous thrombosis caused by short-term administration of ethinylestradiol and cyproterone acetate tablets in adolescents: A case report","authors":"Huayu Han,&nbsp;Cuiyan Wang,&nbsp;Yang Yue,&nbsp;Wei Liu","doi":"10.1111/jog.16261","DOIUrl":"https://doi.org/10.1111/jog.16261","url":null,"abstract":"<p>It is very rare for teenagers to suffer from cerebral venous thrombosis due to oral contraceptives in a short period. Here, we report a 14-year-old girl who developed superior sagittal sinus thrombosis 2 days after oral ethinylestradiol and cyproterone acetate tablets treatment for abnormal uterine bleeding. There were no recorded instances of coagulopathies or strokes in her family or personal medical history. After admission, she experienced two convulsions and was administered diazepam for treatment. Anticoagulant therapy with low-molecular-weight heparin was initiated concurrently. After spending 12 days at our facility receiving medical care, she could be discharged home successfully. Although the risk of thrombosis in adolescent patients is extremely low, clinicians should conduct a comprehensive assessment of patients when taking drugs, and good insight into drug use and actual adverse drug reactions is essential to minimize the risk in practice.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “Prediction of deep vein thrombosis in pregnant women by platelet indices: A retrospective case–control study”","authors":"Fatima Riaz","doi":"10.1111/jog.16265","DOIUrl":"https://doi.org/10.1111/jog.16265","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of anticancer treatment using scalp cooling for patients with gynecological cancer in Japan: A case series study","authors":"Shinya Oki,&nbsp;Yoko Ishihara,&nbsp;Sari Takahashi,&nbsp;Tomoyo Kato,&nbsp;Kana Ietani,&nbsp;Takeshi Makabe,&nbsp;Mizuki Kurihara,&nbsp;Akiko Ohno,&nbsp;Yoshiko Mikami,&nbsp;Hiroshi Yamashita","doi":"10.1111/jog.16270","DOIUrl":"https://doi.org/10.1111/jog.16270","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To evaluate the safety and efficacy of scalp cooling in preventing chemotherapy-induced alopecia among Japanese patients with gynecological cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective study was conducted involving 16 patients with gynecological cancer who underwent chemotherapy with scalp cooling at our institution between January 2021 and April 2024. The completion rate of the planned regimens, the success rate (defined as hair loss ≤50%), hair volume recovery 8–12 weeks after chemotherapy, and adverse events were assessed. Additionally, patient satisfaction was measured using the net promoter score (NPS) following chemotherapy completion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 16 patients included in the study, chemotherapy regimens comprised six courses of combination therapy with paclitaxel plus carboplatin in 11 cases, three courses of the same regimen in three cases, and three courses of combination therapy with docetaxel plus carboplatin in two cases. The overall completion rate of the planned regimens was 75% (12/16 cases). Among the 12 cases, nine were evaluable for alopecia, with a success rate of 33.3%. The proportion of the patients who recovered hair volume from ≤50% to &gt;50% was 83.3% in the occipital region. Adverse events were reported as follows: chills in 75.0%, jaw pain in 68.8%, headache in 31.3%, nausea in 18.8%, and hypertension and hunger in 12.5% each. The NPS for scalp cooling was 26.7 points.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Scalp cooling is effective and safe in preventing hair loss and restoring hair volume in Japanese patients with gynecological cancer, suggesting high patient satisfaction with this treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16270","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical effects between sacrospinous ligament fixation and extraperitoneal high uterosacral ligament suspension for patients: A retrospective cohort clinical trials","authors":"Jiaoyang Song,&nbsp;Xiaohui Sun,&nbsp;Bing Xie,&nbsp;Shiyan Wang,&nbsp;Lei Gao,&nbsp;Xiuli Sun","doi":"10.1111/jog.16264","DOIUrl":"https://doi.org/10.1111/jog.16264","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the study is to compare the effect of extraperitoneal high uterosacral ligament suspension (EHUS) and sacrospinous ligament fixation on lower urinary tract symptoms (LUTS) and anatomical reduction in patients with pelvic organ prolapse (POP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cohort study concluded 91 patients with POP who underwent EHUS or sacrospinous ligament fixation (SSLF) for apical repair. The primary outcome was the effect of the two operations on anatomical reduction. The main secondary outcomes included improvement of questionnaire scores, satisfaction, and subjective prolapse rate. Categorical variables, Student's <i>t</i> test, and the Mann–Whitney <i>U</i> test were used for analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All patients' scores of POP-Q were significantly improved after surgery. The scores of urinary frequency and urgency in the SSLF group improved significantly from 6 months after surgery, with statistical significance (<i>p</i> &lt; 0.05), while the scores of nocturia and urgency in the EHUS group improved from 1 month after surgery (<i>p</i> &lt; 0.05). The scores of questionnaires in both groups were significantly lower than those before surgery, while the EHUS group showed more significant improvement (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>EHUS is easy to operate, has a short operative time, fewer perioperative and postoperative complications, and the apical can be suspended well if the prolapse is not severe. It also has a certain degree of relief for LUTS, which is a new type of operation that is worthy of clinical promotion.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-indicated and physical examination-indicated cervical cerclage in twin versus singleton gestations","authors":"Daphna Amitai Komem,&nbsp;Raanan Meyer,&nbsp;Itai Yagel,&nbsp;Daniel Shai,&nbsp;Roy Mashiach,&nbsp;Israel Hendler,&nbsp;Shali Mazaki-Tovi,&nbsp;Yoav Yinon","doi":"10.1111/jog.16263","DOIUrl":"https://doi.org/10.1111/jog.16263","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To compare the safety and efficacy of ultrasound- and physical examination-indicated cervical cerclage in twin versus singleton gestations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort study of all ultrasound-indicated (cervical length ≤ 25 mm) and physical examination-indicated cerclage cases performed over a 9-year period. The primary outcome was the time interval from cerclage placement to delivery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study cohort included 94 singleton and 16 twin pregnancies. The time interval from cerclage placement to delivery was comparable in singleton and twin gestations (14.77 vs. 12.07 weeks, <i>p</i> = 0.11), as were the rates of preterm births before 28 and 32 weeks. The rate of alive newborns &gt;24 weeks was lower in the twin group (71.9% vs. 88.3%, <i>p</i> = 0.028). Regression analysis identified that cervical dilation, but not twin gestation, was the only factor independently associated with an increased risk for birth before 32 weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasound-indicated and physical examination-indicated cerclage had comparable efficacy in prolonging pregnancy in twin and singleton gestations, though live birth rates were lower in twins.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16263","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between the pelvic organ prolapse quantification system and vaginal noise: A cross-sectional study","authors":"Sima Shamshiri Khamene,&nbsp;Izat Mohammad Khawajah,&nbsp;Elham Feizabad,&nbsp;Maryam Sadr Ameli,&nbsp;Elahe Radmehr,&nbsp;Khadijeh Adabi","doi":"10.1111/jog.16257","DOIUrl":"https://doi.org/10.1111/jog.16257","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Vaginal noise (VN) has recently received attention as an important factor in women's sexual life and satisfaction. It can be influenced by various factors such as genetics, childbirth, age, menopause, and many other factors that are yet to be discovered. The purpose of this study is to investigate the relationship between the Pelvic Organ Prolapse Quantification (POP-Q) system and vaginal sounds and to find out the correlation between VN and sexual function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The correlation between POP-Q measurements and VN and its impact on female sexual life was investigated in 851 women referred to the female pelvic medicine and reconstructive surgery clinic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>VN was reported in 26.3% of the patients. It was significantly higher in younger cases and premenopause. VN had no significant association with cigarettes, BMI, gravidity, or abortion. Feeling of heaviness in the pelvic area, dyspareunia, anorgasmia, and partners sexual dissatisfaction were significantly higher in cases with VN. No significant relationship was found between VN and reduction in sexual desire and vaginal dryness. Patients with higher-stage anterior vaginal wall prolapse had significantly fewer complaints of VN. Stage 3 anterior vaginal wall prolapse had a lower chance of vaginal noise, OR = 0.2. Mean Aa and Ba were significantly higher in cases without VN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this study, we found a significant relationship between VN and anterior vaginal wall prolapse in a way that Stage 3 had a lesser chance of VN. No relation was found in the posterior or apical vaginal prolapse.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “Will the day come when opinion and letter pieces disappear from the medical journals?”","authors":"Himel Mondal","doi":"10.1111/jog.16262","DOIUrl":"https://doi.org/10.1111/jog.16262","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}