Journal of Obstetrics and Gynaecology Research最新文献

{"title":"Factors influencing healthy dietary behavior changes among patients with gestational diabetes mellitus during pregnancy: A meta-synthesis using the theoretical domains framework","authors":"Qianqian Li,&nbsp;Yueshuai Pan,&nbsp;Yi Li,&nbsp;Ruting Gu,&nbsp;Jingyuan Wang,&nbsp;Yan Zhang,&nbsp;Xinwei Zhang,&nbsp;Yuan Zhu,&nbsp;Lili Wei","doi":"10.1111/jog.16294","DOIUrl":"https://doi.org/10.1111/jog.16294","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To examine factors that facilitate and impede healthy dietary behavior modification in patients with gestational diabetes mellitus (GDM). Additionally, it sought to assess the strength of the evidence for these factors and offer insights into promoting positive behaviors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This systematic review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting standards. We searched seven databases in February 2023 to include qualitative studies related to patients with GDM that explored their perceptions of and changes in healthy eating behaviors. Two researchers independently screened the articles, assessed their quality, extracted data, and coded the factors using the theoretical domain framework. For the factors involved, we performed a meta-synthesis based on their frequency and assigned a confidence level to determine their level of evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 32 of the 536 extracted articles. Barriers identified by high levels of evidence include: “Environmental context and resources,” “Social influences,” “Knowledge,” “Emotion,” and “Social/professional roles and Identity.” The facilitators identified by high levels of evidence include the following: “Beliefs about consequences,” “Social influences,” “Environmental context and resources,” “Skill,” and “Memory, attention, and decision processes.”</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This meta-synthesis highlights that healthy eating behavior change is influenced by the interaction of factors at different levels of individuals, organizations, and sociocultural environments. Furthermore, we established a framework that displayed the associations between these factors, giving prominence to those with higher levels of evidence. This framework will aid researchers in identifying priority areas for intervention and facilitating the implementation of high-quality strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of insurance coverage on access to assisted reproductive technology: A nationwide survey in Japan (the IZANAMI project)","authors":"Aika Wada,&nbsp;Mitsutoshi Yamada,&nbsp;Hiromitsu Shirasawa,&nbsp;Seung Chik Jwa,&nbsp;Keiji Kuroda,&nbsp;Miyuki Harada,&nbsp;Yutaka Osuga","doi":"10.1111/jog.16292","DOIUrl":"https://doi.org/10.1111/jog.16292","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Assisted reproductive technology (ART) is a well-established infertility treatment. However, financial and geographical barriers can hinder patient access. The Japanese government implemented insurance coverage in April 2022 for specific ART treatments. This study assessed the effects of insurance coverage on ART utilization and accessibility.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An online survey was administered to 427 ART facilities that participated in a pre-policy assessment from December 1, 2023, to January 30, 2024.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 283 facilities responded (response rate: 66.3%). The number of ART patients increased by 4.0% (217 699–226 401) following the implementation of insurance coverage. The number of insured patients aged 25–43 years increased by 6.6%, with a notable increase of 22.9% (range: 44 144–54 253) in the 25- to 34-year age group. However, the number of uninsured patients aged ≥44 decreased by 16.3%; 172 facilities experienced an increased number of patients, whereas 111 facilities experienced no increase or decline. Patient growth rates were significantly higher in rural areas than in metropolitan regions (mean difference: 0.07; 95% confidence interval: 0.0–0.1; <i>p</i> = 0.03). Although there was a significant negative association between the proportion of out-of-pocket treatment and the rate of patient increase (<i>p</i> = 0.02), no such association was observed in rural areas (<i>p</i> = 0.68).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Insurance coverage improved patient access to ART services, especially for those in their 20s and early 30s. However, the number of patients in the uninsured group decreased significantly. Accessibility in rural areas also notably improved. These findings highlight the importance of economic support for enhancing ART accessibility.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16292","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143830983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of genital self-image during pregnancy with the attitude toward sexuality","authors":"Hamide Aygör,&nbsp;Vesile Koçak","doi":"10.1111/jog.16291","DOIUrl":"https://doi.org/10.1111/jog.16291","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Genital self-image is one of the significant components of sexual health. Changes in the female body during pregnancy occur also in genital organs and affect the pregnant woman's genital self-image. In this respect, this study aimed to evaluate the genital self-image during pregnancy and its association with the attitude toward sexuality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is descriptive and correlational research. The research data were collected at antenatal polyclinics of a university hospital from November 2022 to January 2023. A total of 319 pregnant women who were married, sexually active, and healthy were included in the study. The Survey Form, the Female Genital Self-Image Scale (FGSIS), and the Attitude Scale toward Sexuality during Pregnancy (AStSdP) were used in the collection of research data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean scores obtained by pregnant women from the FGSIS and the AStSdP were successively 14.50 ± 4.15 and 88.01 ± 14.46 points. The factors affecting the attitude toward sexuality during pregnancy were the genital self-image and the duration of marriage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In the study, it was discerned that pregnant women had a negative genital self-image and held negative attitudes toward sexuality during pregnancy. Also, it was found that genital self-image and the duration of marriage affected the attitude toward sexuality during pregnancy. Therefore, in pregnancy follow-ups, women's genital self-image and attitudes toward sexuality should be identified, and training programs and consultancy services on these topics should be offered to women.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AOFOG recommendation on postpartum hemorrhage care bundle approach to improve adherence to the WHO guidelines","authors":"U. D. P. Ratnasiri,&nbsp;Pisake Lumbiganon,&nbsp;John Tait,&nbsp;Rohana Haththotuwa,&nbsp;Krishnendu Gupta","doi":"10.1111/jog.16288","DOIUrl":"https://doi.org/10.1111/jog.16288","url":null,"abstract":"<p>Global maternal mortality estimates 287 000 deaths in 2020. Obstetric hemorrhage is a leading cause contributing to 27% of all maternal deaths. The Asia Oceania Federation of Obstetrics and Gynaecology (AOFOG) recommendation aims to reduce the postpartum hemorrhagic deaths with the use of a care bundle approach published by the World Health Organization in the Asia Oceania region. The care bundle approach has been shown to reduce the risk of the primary outcome, a composite of severe postpartum hemorrhage, laparotomy for bleeding, or death from bleeding, compared to usual care among patients having vaginal delivery. In a large, international, parallel cluster-randomized trial, the E-MOTIVE trial. The AOFOG recommends the care bundle approach on postpartum hemorrhage to improve adherence to the World Health Organization guidelines in achieving reduction of morbidity and mortality in maternal death with postpartum hemorrhage.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and predictors of vaginal douching among pregnant women","authors":"Pınar Kara","doi":"10.1111/jog.16286","DOIUrl":"https://doi.org/10.1111/jog.16286","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to determine the prevalence of vaginal douching and its predictors among pregnant women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional and multi-center study was conducted from March to November 2024, involving 1523 pregnant women receiving routine antenatal care at four government hospital obstetric outpatient clinics. Data were collected using a structured questionnaire addressing personal and vaginal douching practices. Statistical analyses were performed at a significance level of <i>p</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of vaginal douching among the participants was 30.7%. The primary motivation for vaginal douching was personal hygiene, with water being the most frequently used substance. Information about the practice was predominantly obtained from family elders, friends, or individual experience. Misconceptions regarding the hygienic and health implications of vaginal douching were prevalent among participants. Despite awareness of its association with genital infections or related problems, many participants continued the practice. Multiple logistic regression analysis identified significant predictors of vaginal douching, including perceptions that it is hygienic, healthy, and associated with risks of genital infections/problems; a history of genital infections/problems within the previous year; receiving information about vaginal douching from family elders; engaging in sexual intercourse 1–2 times per week during the current pregnancy; being in the third trimester; being unemployed; and having completed secondary or high school education. The independent variables accounted for 73.9% of the variance in the dependent variable (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study provides essential insights into the prevalence of vaginal douching among pregnant women and highlights their perceptions and motivations for engaging in this practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between loneliness perception and breastfeeding self-efficacy and breastfeeding behaviors in mothers","authors":"Rukiye Demir,&nbsp;Resmiye Kaya Odabaş,&nbsp;Ayten Taşpınar","doi":"10.1111/jog.16280","DOIUrl":"https://doi.org/10.1111/jog.16280","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Breast milk and breastfeeding affect the health of the child, the mother, and indirectly the public. Therefore, it is important to determine the breastfeeding self-efficacy of mothers, breastfeeding behaviors, and the factors affecting them, and to eliminate the factors that negatively affect breastfeeding.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The study was conducted to examine the relationship between the perception of loneliness in mothers and breastfeeding self-efficacy and breastfeeding behaviors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This descriptive and correlational study was conducted in Turkey between March and November 2024 with 382 mothers (<i>n</i> = 382). The data were collected using the Descriptive Information Form, Breastfeeding Self-Efficacy Scale (BSES), and Social and Emotional Loneliness Scale (SELSA-S).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean total score of the mothers in the study was 43.72 ± 11.13 and the mean total score of SELSA-S was 59.67 ± 13.25. In the study, it was found that those who were university graduates, were employed, received education about breastfeeding, were currently breastfeeding, as well as those who exclusively breastfed for the first 6 months, received spousal support while breastfeeding, had statistically significantly higher mean total scores on the BSES and lower mean total scores on the SELSA-S than the others. Additionally, receiving general social support and specifically from their spouses also contributed to these higher scores. In addition, a high-level negative linear relationship was found between the BSES and SELSA-S total and sub-dimensions (<i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>It was concluded that the perception of social and emotional loneliness negatively affected breastfeeding self-efficacy and some breastfeeding behaviors in mothers with infants aged 0–24 months.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive value of triglyceride-glucose index, lipid accumulation product and lipid ratio on metabolic syndrome in polycystic ovary syndrome patients","authors":"Ning Ma,&nbsp;Xiao-Ning Cui,&nbsp;Na Wang","doi":"10.1111/jog.16283","DOIUrl":"https://doi.org/10.1111/jog.16283","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify reliable indicators to predict the occurrence of metabolic syndrome (MetS) and to provide an effective way to prevent it in polycystic ovary syndrome (PCOS), we explored the relationships between triglyceride-glucose index (Ty-G), lipid accumulation product (LAP), lipid accumulation product ratio, and MetS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We detected the relationship between the Ty-G index, LAP, lipid ratio, and incidence of MetS. In addition, we classified the Ty-G index and LAP into tertiles to determine the efficacy of these indicators in predicting the risk of MetS. Finally, the effects of the Ty-G index, LAP, and lipid ratio on the prediction of MetS were evaluated with the receiver operating characteristic (ROC) curve.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our results indicate that the incidence of MetS was 38% in 134 patients with PCOS, and that the Ty-G index, LAP, and lipid ratio were independent risk factors for MetS. In addition, the incidence of MetS significantly increased with Ty-G index and LAP. The ROC curve showed that the Ty-G index, LAP, and lipid ratio all showed good performance in predicting the occurrence of MetS in PCOS patients, but the Ty-G index had the highest predictive value, with a cut-off value of 8.70.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our study revealed that the Ty-G index plays an important role in predicting the occurrence of MetS in PCOS patients. In addition, monitoring blood glucose and lipid levels is an effective approach for preventing MetS in PCOS patients clinically regardless of age, and weight management should be strictly implemented in overweight and obese patients to prevent MetS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of erector spinae plane block and transversus abdominis plane block on quality of recovery and postoperative pain after laparoscopic hysterectomy; randomized, double-blinded clinical trial","authors":"Pelin Dilsiz,&nbsp;İsmail Gökbel,&nbsp;Yaşam Umutlu,&nbsp;Hüseyin Alp Ertuğrul,&nbsp;Sinem Sari","doi":"10.1111/jog.16284","DOIUrl":"https://doi.org/10.1111/jog.16284","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The erector spinae plane (ESP) block is used in various surgical procedures as an effective and safe regional analgesia technique. Unlike other plane blocks, the ESP block provides cutaneous and visceral analgesia by involving both ventral and dorsal roots. This study compared the ESP block and the transversus abdominis plane (TAP) block after laparoscopic hysterectomy, aiming primarily to compare quality of recovery (QoR) and secondarily to compare pain scores.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective randomized controlled study involved 64 patients. After ethical approval and patient consent, patients undergoing elective laparoscopic hysterectomy were randomly assigned to two groups: Group E received a bilateral ESP block, and Group T received a bilateral lateral TAP block. In the recovery room, patients with a numerical rating score (NRS) of 4 or above received intravenous meperidine as rescue analgesia. The same postoperative analgesia plan was applied to all patients, including intravenous paracetamol and intramuscular diclofenac sodium. Tramadol was administered if the NRS score was 4 or above. Preoperative and postoperative QoR scores, pain scores, rescue analgesia use, nausea and vomiting, antiemetic use, unexpected side effects, mobilization time, and discharge time were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>When comparing preoperative and postoperative QoR scores, it was found that the decreases in scores were less in Group E. NRS scores were lower at the 4th, 8th, 12th, and 16th hours in Group E. Mobilization times were also shorter in Group E.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The ESP block is more effective than the TAP block in improving the quality of recovery and pain scores after laparoscopic hysterectomy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143786941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “Is it ethical to use ChatGPT to write scientific papers?”","authors":"Minna J. Hsu,&nbsp;Govindasamy Agoramoorthy","doi":"10.1111/jog.16274","DOIUrl":"https://doi.org/10.1111/jog.16274","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of miRNA polymorphisms on male and female infertility and recurrent implantation failure","authors":"Reza Alibakhshi,&nbsp;Masoud Soleimani,&nbsp;Kheirollah Yari,&nbsp;Amir Ali Kalhori,&nbsp;Mohsen Karami,&nbsp;Mohammad Reza Kalhori","doi":"10.1111/jog.16281","DOIUrl":"https://doi.org/10.1111/jog.16281","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>MiRNAs regulate gene expression, impacting reproductive health, such as infertility and implantation failure. This study investigated the association between miRNA polymorphisms and male infertility (azoospermia, oligospermia), female infertility (endometriosis), and recurrent implantation failure in IVF.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In order to find relevant articles, a search was conducted in PubMed, WOS, Scopus, and the Cochrane Library databases using Mesh terms and Entry terms with the keywords (miRNA OR microRNA polymorphism) AND (abortion OR miscarriage OR infertility OR sterility OR pregnancy loss OR implantation failure).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study revealed miRNA polymorphisms linked to a higher risk of male and female infertility and repeated implantation failure in IVF. These results underscore the significance of genetic variations in miRNAs in developing reproductive issues and the promise of personalized treatment strategies guided by genetic profiles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These results provide valuable insights into the genetic basis of infertility and emphasize the need for further research to develop targeted diagnostic tools and therapies. Understanding the role of miRNA polymorphisms in reproductive health has significant implications for improving outcomes for couples struggling with infertility. By elucidating the genetic factors contributing to infertility, this study paves the way for personalized approaches to diagnosis and treatment, ultimately enhancing reproductive care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}