Journal of Obstetrics and Gynaecology Research最新文献

{"title":"Successful Live Birth Following Micro-Stimulation IVF in a Patient With Recurrent Serous Borderline Ovarian Tumor: A Case Report","authors":"Junling Wang,&nbsp;Ben Yuan,&nbsp;Shuhong Luo,&nbsp;Xiumei Wang,&nbsp;Ziqin Lu,&nbsp;Junbiao Mao","doi":"10.1111/jog.70503","DOIUrl":"10.1111/jog.70503","url":null,"abstract":"<div>\u0000 \u0000 <p>Fertility preservation in women with recurrent serous borderline ovarian tumors (SBOTs) remains clinically challenging because of concerns regarding oncological safety and limited evidence. We report the case of a young woman with FIGO Stage IIIA1 SBOT with lymph node involvement who experienced multiple recurrences with adverse pathological features, including micropapillary architecture and stromal microinvasion. Following multidisciplinary discussion and comprehensive counseling, a brief micro-stimulation in vitro fertilization protocol was performed for embryo cryopreservation prior to repeat fertility-sparing surgery to minimize treatment delay. After complete macroscopic disease clearance, frozen-thawed embryo transfer was carried out, resulting in a successful term live birth. No clinical or radiological evidence of recurrence was observed during the available follow-up period. This case suggests that an individualized fertility-first strategy may be considered in carefully selected patients with advanced recurrent SBOT under strict multidisciplinary evaluation and close surveillance.</p>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two-Dimensional Characterization of Maternal BMI and Height Associations With Pregnancy and Perinatal Outcomes After Frozen Embryo Transfer","authors":"Shuhei So,&nbsp;Nao Murabayashi,&nbsp;Wakasa Yamaguchi,&nbsp;Naomi Miyano,&nbsp;Misa Namba,&nbsp;Fumiko Tawara","doi":"10.1111/jog.70506","DOIUrl":"10.1111/jog.70506","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To characterize maternal body mass index (BMI) and height as two nearly independent body-size dimensions in relation to pregnancy and perinatal outcomes after frozen–thawed embryo transfer (FET), and assess whether their joint evaluation reveals patterns not captured by BMI alone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In a single-center retrospective cohort of 10 059 FET cycles, dose–response relationships of BMI and height with 15 pregnancy-related outcomes were modeled using restricted cubic splines with modified Poisson regression and robust variance estimators. A joint additive model generated two-dimensional risk surfaces adjusted for maternal age, endometrial preparation, and obstetric covariates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>BMI was significantly associated with nine of 15 outcomes and height with seven. Two-dimensional risk maps showed outcome-specific patterns: hypertensive disorders of pregnancy were predominantly BMI-associated, whereas small-for-gestational-age and gestational diabetes reflected both dimensions, with higher risks in the low-BMI/short-stature and high-BMI/short-stature regions, respectively. Exploratory subgroup analyses by endometrial preparation method suggested possible heterogeneity for cesarean section, large-for-gestational-age, and miscarriage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Joint evaluation of BMI and height revealed heterogeneous body-size risk patterns—predominantly BMI-associated, height-associated, or combined—that BMI alone does not capture. Because height is readily available before pregnancy, considering it with BMI may refine body-size risk assessment after FET.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Global Research Landscape of Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES): Türkiye's Position, Contribution, and Collaboration Networks (2012–January 2026)","authors":"Erkan Mavigök","doi":"10.1111/jog.70496","DOIUrl":"https://doi.org/10.1111/jog.70496","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study evaluated Türkiye's position and contribution within the global research landscape of vaginal natural orifice transluminal endoscopic surgery (vNOTES) from 2012 to January 15, 2026.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Web of Science, Scopus, and TÜBİTAK ULAKBİM TR Index searches yielded 466, 689, and 210 records, respectively (total <i>n</i> = 1365). After removal of 415 duplicates, 125 ineligible document types, and 353 records failing relevance or analytical eligibility criteria, 472 peer-reviewed articles and reviews were included. VOSviewer and CiteSpace were used for bibliographic coupling, coauthorship, co-citation, and temporal mapping. International country rankings and citation-based networks were calculated from the comparable Web of Science and Scopus metadata.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Türkiye ranked second in publication output with 47 documents and showed high collaboration intensity (total link strength = 472). Institutional and author networks indicated a transition from isolated single-center reports toward multicenter collaboration, including the TR-MIGS platform. Thematic mapping showed expansion from feasibility studies toward high-BMI populations, emergency applications, pelvic-floor procedures, and other complex indications. Records assigned to 2026 reflect indexing only through January 15 and were treated as a partial-year research-front snapshot.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Türkiye has become a prominent contributor to global vNOTES research. Its contribution is characterized by dense national collaboration and diversification toward complex clinical applications; however, bibliometric prominence should not be interpreted as direct evidence of clinical superiority.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148994608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Impact of Serum microRNA Profiles on the Progression-Free Survival of Patients With High-Grade Serous Ovarian Cancer Receiving Neoadjuvant Chemotherapy","authors":"Takashi Uehara,&nbsp;Juntaro Matsuzaki,&nbsp;Yusuke Yamamoto,&nbsp;Hiroshi Yoshida,&nbsp;Yuto Ogawa,&nbsp;Junichiro Miura,&nbsp;Hitoshi Fujimiya,&nbsp;Satoko Takizawa,&nbsp;Akira Yokoi,&nbsp;Kan Yonemori,&nbsp;Ken Kato,&nbsp;Mitsuya Ishikawa,&nbsp;Takahiro Ochiya","doi":"10.1111/jog.70500","DOIUrl":"10.1111/jog.70500","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>High-grade serous ovarian cancer is a deadly cancer with a poor prognosis. Serum microRNAs have been used to detect and diagnose various cancers. We aimed to investigate the prognostic impact of serum microRNA profiles pre-, peri-, and post-primary treatment on the progression-free survival of patients with advanced high-grade serous ovarian cancer receiving neoadjuvant chemotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients were prospectively recruited, and pre-, peri-, and post-treatment blood samples were collected. MicroRNA microarray results, together with the clinical and surgical data, were analyzed using Cox regression with leave-one-out least absolute shrinkage and selection operator for progression-free survival.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 29 patients were included. A combined analysis of pre-treatment serum microRNAs and clinical factors showed a higher c-index (0.86) for distinguishing high- and low-risk groups for poor progression-free survival outcomes compared to analyzing each factor alone (0.70 and 0.64, respectively). The high-risk group exhibited significantly worse progression-free survival (log-rank, <i>p</i> &lt; 0.01). The serum microRNA profile at 3 months post-treatment showed outstanding discrimination (c-index of 1.00). Changes in the microRNA profile between pre- and peri-treatment had no prognostic impact; however, the difference between pre-treatment and 3 months post-treatment exhibited excellent discrimination (c-index of 1.00).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In patients with advanced high-grade serous ovarian cancer who received neoadjuvant chemotherapy, a combination of the pre-treatment serum microRNA profiles and clinical factors, or the 3-month post-treatment serum microRNA profile could distinguish between those in high- and low-risk groups for poor progression-free survival outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical, Uterine, and Ovarian Cancers in Chinese Women Aged 55 Years and Older: Burden, Temporal Trends, Risk Attribution, and Future Projections From the Global Burden of Disease Study 2021","authors":"Xin Zhang,&nbsp;Tao Zhu,&nbsp;Zhan Gao,&nbsp;Zhenhui Han,&nbsp;Shang Zheng","doi":"10.1111/jog.70413","DOIUrl":"10.1111/jog.70413","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To compare the burden, temporal trends, risk factor attribution, and future projections of cervical, uterine, and ovarian cancers among Chinese women aged 55 years and older.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a population-based descriptive and projection analysis using data from the Global Burden of Disease Study 2021. Incidence, mortality, disability-adjusted life years (DALYs), and corresponding age-standardized rates for cervical, uterine, and ovarian cancers were extracted for 1990–2021. Age-specific burden, temporal trends, and attributable risk factors were examined. Incidence and mortality from 2022 to 2036 were projected using a Bayesian age-specific trend model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From 1990 to 2021, the absolute numbers of incident cases, deaths, and DALYs increased for all three cancers among Chinese women aged 55 years and older, whereas age-standardized mortality and DALY rates generally declined. In 2021, cervical cancer showed the highest overall burden, with mortality rates increasing markedly in the oldest age groups. Uterine cancer showed the largest increase in incidence age-standardized rate and a burden concentrated mainly in the younger segment of older women. Ovarian cancer showed a relatively unfavorable mortality pattern and was projected to have increasing incidence and mortality through 2036. Risk attribution differed by cancer type: cervical cancer mortality was mainly attributable to unsafe sex, uterine cancer mortality to high body mass index, and ovarian cancer mortality to mixed metabolic and environmental or occupational risks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Cervical, uterine, and ovarian cancers remain substantial and heterogeneous health burdens among older Chinese women. Despite declines in age-standardized mortality and DALY rates, population aging is likely to increase the absolute burden. Age-specific prevention, screening, early detection, and resource allocation are needed for older women in China.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the 2016 Kumamoto Earthquake on ART Subsidy Applications in Kumamoto Prefecture: Interrupted Time-Series Analysis","authors":"Rumi Sasaki,&nbsp;Takashi Ohba,&nbsp;Miwa Nakamura,&nbsp;Kenyu Hashimoto,&nbsp;Eiji Kondoh","doi":"10.1111/jog.70498","DOIUrl":"10.1111/jog.70498","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Natural disasters may disrupt access to assisted reproductive technology (ART) services. This study evaluated the impact of the 2016 Kumamoto earthquake on ART utilization in Kumamoto Prefecture, accounting for nationwide trends and policy changes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted an interrupted time-series analysis using annual ART subsidy application data in Kumamoto Prefecture from 2005 to 2020. Nationwide application counts were included as an offset to adjust for national trends related to the 2016 subsidy policy revision. Age-specific patterns were also examined using normalized indices.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In analysis adjusted for nationwide trends, ART subsidy applications showed a significant immediate reduction in 2016 (incidence rate ratio [IRR] = 0.84, 95% confidence interval [CI]: 0.77–0.91), followed by a gradual recovery (IRR for slope change = 1.06, 95% CI: 1.04–1.09). The decline was more pronounced among women aged 40 years and older, whereas applications among younger women remained relatively stable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The 2016 Kumamoto earthquake was associated with a substantial decline in ART subsidy applications in Kumamoto Prefecture beyond nationwide trends. This reduction was most pronounced among women aged 40 years and older, suggesting age-related differences in responses to disaster-related disruptions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Carotid Intima-Media Thickness and Serum Endocan Levels in Surgical and Natural Menopause With Premenopausal Women","authors":"Ayse Derya Topal,&nbsp;Fisun Vural,&nbsp;Ayse Deniz Ertürk Coskun,&nbsp;Sibel Aydin Aksu,&nbsp;Kubra Bozali,&nbsp;Eray Metin Güler","doi":"10.1111/jog.70497","DOIUrl":"10.1111/jog.70497","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Menopause is associated with increased cardiovascular risk due to estrogen depletion. This study aimed to compare carotid intima–media thickness (CIMT) and serum endocan levels in women with natural menopause, surgical menopause, and premenopausal status, and to evaluate their potential roles as biomarkers for cardiovascular risk stratification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective observational study included 88 healthy women aged 45–60 years: 32 with surgical menopause, 30 with natural menopause, and 26 who were premenopausal. Serum endocan concentrations were measured using an enzyme-linked immunosorbent assay, and bilateral CIMT was assessed ultrasonographically. Between-group comparisons were performed using appropriate parametric or non-parametric tests. Multivariable linear regression analyses adjusted for age and body mass index (BMI) were performed. Serum endocan was natural-log transformed before multivariable analysis because of its skewed distribution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Serum endocan concentrations differed significantly among the three groups (overall <i>p</i> &lt; 0.001), with the highest levels in surgical menopause, followed by natural menopause and premenopause. The association between menopausal group and log-transformed endocan remained significant after adjustment for age and BMI (overall <i>p</i> &lt; 0.001). Overall mean CIMT did not differ significantly among the groups in either unadjusted (<i>p</i> = 0.913) or adjusted analyses (<i>p</i> = 0.703). Age, but not menopausal group or BMI, was independently associated with overall mean CIMT (<i>p</i> = 0.003).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Serum endocan levels were independently associated with menopausal status after adjustment for age and BMI, with the highest concentrations observed in women with surgical menopause. In contrast, CIMT was not independently associated with menopausal status. These findings support further investigation of endocan as a potential marker of menopause-associated endothelial alterations. However, prospective longitudinal studies are strictly required to validate this indirect hypothesis and establish causality.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sacrum Metastasis in Stage IA Endometrial Carcinoma 13 Years After Surgery: A Case Report","authors":"Kei Hattori,&nbsp;Yuta Kobayashi,&nbsp;Mayu Shibata,&nbsp;Masataka Nomoto,&nbsp;Toshimitsu Furui,&nbsp;Yosuke Kawai","doi":"10.1111/jog.70493","DOIUrl":"10.1111/jog.70493","url":null,"abstract":"<div>\u0000 \u0000 <p>Recurrence of early-stage endometrial cancer (EC) most commonly occurs within 5 years after initial surgery, and ultra-late recurrence more than 10 years after treatment is extremely rare. Bone metastasis from EC is also relatively uncommon. We report a case of Stage IA EC with sacral metastasis occurring 13 years after curative surgery. The patient is a 48-year-old woman who underwent radical hysterectomy for EC 13 years ago. She completed 5 years of follow-up with no recurrence. She was referred to our hospital because of a sacral tumor accompanied by pain and bladder and bowel dysfunction. A biopsy confirmed sacral metastasis from EC. Radiotherapy and chemotherapy resulted in improvement of neurological symptoms and tumor regression. This case highlights the potential efficacy of multidisciplinary treatment for not only the tumor but also neurological symptoms.</p>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unani Herbal Vaginal Douche for Antibiotic-Refractory Chronic Cervicitis: A Case Series","authors":"Tabasum Rouf,&nbsp;Iftikhar Ahmad","doi":"10.1111/jog.70499","DOIUrl":"https://doi.org/10.1111/jog.70499","url":null,"abstract":"<div>\u0000 \u0000 <p>Chronic cervicitis is a clinical syndrome characterized by persistent inflammation of the cervical epithelium that is often associated with vaginal discharge, dyspareunia, post-coital bleeding, and fatigue. This prospective case series included three patients diagnosed with chronic cervicitis based on clinical and diagnostic findings. A Unani herbal vaginal douche was prepared and administered once daily for 21 days, and the patients were followed up for 2 months. Symptoms improved in all three patients. This case series highlights that Unani herbal vaginal douche may represent a potentially useful and well-tolerated complementary therapeutic option for chronic cervicitis. However, larger controlled studies are needed to confirm these findings and establish the efficacy and safety of this intervention.</p>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148943081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Study of Knowledge, Attitude, and Practice Interventions Based on the Transtheoretical Model on Improving the Perioperative Experience of Patients Undergoing Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES)","authors":"Hong Li,&nbsp;Bin Wang","doi":"10.1111/jog.70494","DOIUrl":"10.1111/jog.70494","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Aim&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To investigate the application of the knowledge, attitude, and practice (KAP) intervention based on the transtheoretical model (TTM) in the perioperative nursing of patients undergoing vaginal natural orifice transluminal endoscopic surgery (vNOTES) and to examine its relationship with indicators related to the perioperative experience.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;91 patients who underwent vNOTES were retrospectively selected as the study subjects. Based on differences in nursing interventions, the patients were divided into a study group (&lt;i&gt;n&lt;/i&gt; = 49, receiving KAP intervention based on the TTM) and a control group (&lt;i&gt;n&lt;/i&gt; = 42, receiving routine perioperative interventions). This was a non-randomized observational study with time-sequential grouping. It primarily compared surgical indicators (operative time, intraoperative blood loss), intraoperative body temperature, postoperative recovery indicators (time to bowel sound recovery, anal exhaust time, defecation time, and time to ambulation), the incidence of perioperative adverse events, nursing satisfaction, anxiety and depression scores, and VAS scores within 72 h postoperatively. Multivariate logistic regression analysis was used to identify factors associated with the occurrence of perioperative adverse events.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;(1) Intraoperative blood loss in the study group was significantly lower than in the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). (2) Body temperature at time points T1, T2, T3, and T4 was higher in the study group compared to the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). (3) The study group showed earlier anal exhaust time, defecation time, and time to ambulation than the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). (4) The incidence of adverse reactions was lower, while the nursing satisfaction rate was higher in the study group than in the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). (5) After nursing, anxiety and depression scores were lower in the study group compared to the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). These findings should be interpreted cautiously in view of potential residual confounding.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In this retrospective observational study, the KAP intervention based on the TTM was associated with perioperative temperature maintenance, improved postoperative recovery, reduced pain and negative emotions, and increased nursing satisfaction in patients undergoing vNOTES, suggesting that it may have clinical value. However, because of the non-randomized design with time-sequential grouping, further validation is needed through prospective, multicenter","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 9","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148930115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}