Journal of Obstetrics and Gynaecology Research最新文献

{"title":"A Case Report of a Postmortem Intrauterine Fetal Magnetic Resonance Imaging That Identified an Umbilical Cord Factor as the Cause of Fetal Death","authors":"Kaho Sone,&nbsp;Takashi Iizuka,&nbsp;Kotaro Yoshida,&nbsp;Yuka Tanaka,&nbsp;Kyosuke Kagami,&nbsp;Kaoru Abiko","doi":"10.1111/jog.70097","DOIUrl":"10.1111/jog.70097","url":null,"abstract":"<p>Compared to conventional autopsies, using postmortem fetal imaging techniques to investigate the cause of intrauterine fetal demise (IUFD) allows for shorter analysis times and increased consent rates from parents. We reported a case of IUFD in which postmortem fetal magnetic resonance imaging (MRI) was performed before delivery. We confirmed the umbilical abnormalities on MRI: a true knot, hypocoiled, and entangled with the fetal trunk. Notably, the umbilical cord entanglement observed on MRI had been released at the time of delivery. These MRI findings supported the umbilical cord abnormality as the probable cause of the IUFD. Postmortem intrauterine fetal MRI can identify umbilical cord entanglement before delivery, which could not otherwise be detected by conventional examinations. This case demonstrates the potential utility of postmortem intrauterine fetal MRI for evaluating the placenta and umbilical cord in IUFD cases.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 10","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early warning systems to predict severe complications during preterm and postpartum: A scoping review","authors":"Eishin Nakamura,&nbsp;Katsuhiko Naruse,&nbsp;Ryuta Miyake,&nbsp;Tetsuya Hara,&nbsp;Marie Furuta,&nbsp;Hiroaki Tanaka,&nbsp;Shigetaka Matsunaga,&nbsp;Atsushi Sakurai,&nbsp;the Japan Resuscitation Council (JRC), Guideline Editorial Committee","doi":"10.1111/jog.70079","DOIUrl":"10.1111/jog.70079","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Early warning systems (EWSs) are widely used in obstetric care to predict severe maternal complications, including postpartum hemorrhage (PPH) and sepsis. However, variations in the definitions of both EWS and target conditions hinder direct comparisons and meta-analyses. This scoping review aimed to systematically identify diagnostic accuracy studies evaluating EWS for predicting severe maternal conditions and to explore trends in this field.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines. A systematic search of the MEDLINE/PubMed and CENTRAL databases was conducted up to July 12, 2024. Eligible studies included diagnostic accuracy studies assessing EWS in obstetric populations. Two reviewers independently screened studies, extracted data, and summarized study characteristics, including index tests and target conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 93 studies involving 697,558 patients were included. The most frequently evaluated index test was the shock index (SI; 38 studies, 41%), followed by the Modified Early Obstetric Warning Score (19 studies, 20.4%) and the Obstetric Early Warning Score (10 studies, 10.8%). PPH was the most common target condition (46 studies, 49.4%), followed by sepsis (30 studies, 32.3%) and maternal death (21 studies, 22.6%). The combination of SI and PPH was most frequently assessed (20 studies).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Despite the widespread adoption of EWS in obstetric care, the marked heterogeneity in both index tests and outcome definitions highlights the need for standardized criteria and further diagnostic research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased recovery of Streptococcus agalactiae from vaginal–rectal swabs using a selective enrichment broth medium","authors":"Satoshi Nakano,&nbsp;Yuri Hasegawa,&nbsp;Shota Koide,&nbsp;Yumiko Hosaka,&nbsp;Kasumi Ishida-Kuroki,&nbsp;Sayoko Kawakami,&nbsp;Wataru Hayashi,&nbsp;Liansheng Yu,&nbsp;Shizuo Kayama,&nbsp;Noriko Miyashita,&nbsp;Koh Nagata,&nbsp;Shoko Miura,&nbsp;Yo Sugawara,&nbsp;Hiroaki Miyazaki,&nbsp;Motoyuki Sugai,&nbsp;Kiyonori Miura","doi":"10.1111/jog.70084","DOIUrl":"10.1111/jog.70084","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of this study was to clarify whether the detection rate of group B <i>Streptococcus</i> (GBS) in screening tests for pregnant women at 35–37 weeks of gestation increases using the selective enrichment media available in Japan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Vaginal–rectal swabs were collected from pregnant women at 35–37 weeks of gestation from nine obstetric medical institutions in the Nagasaki Prefecture. The collected swabs were inoculated into selective enrichment media and directly plated onto blood agar to investigate the differences in the isolation frequencies of GBS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We collected vaginal–rectal swabs from 116 individuals and successfully isolated GBS from 22 individuals (19.0%) using a selective enrichment broth. When the swabs were directly plated onto blood agar for isolation, GBS was not isolated in nine (40.9%) out of the 22 positive samples. Among these nine samples, six (66.7%) showed reduced pigment production in at least one of the selective enrichment broths that detected GBS based on pigment production.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In a GBS screening test for pregnant women, use of a selective enrichment broth resulted in an approximately 1.7-fold increase in the number of positive samples compared to the direct plating method on blood agar. Although not described in the American Society for Microbiology guidelines, RambaQUICK GBS broth and Poamedia semisolid medium for GBS, both available in Japan, detected GBS significantly more effectively than the direct plating method on blood agar. This finding supports the utility of selective enrichment broths for the GBS screening of pregnant women.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “potential preoperative three-dimensional computed tomography for para-aortic lymphadenectomy in gynecological malignancies”","authors":"Qiming Wu,&nbsp;Zilin Gong,&nbsp;Chen Liu","doi":"10.1111/jog.70064","DOIUrl":"10.1111/jog.70064","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron metabolism study: The characteristics of iron metabolism in patients with ovarian endometriosis complicated with infertility","authors":"Limian Huang,&nbsp;Weiling Qin,&nbsp;Tongye Su,&nbsp;Haiyan Pang,&nbsp;Delong Xie,&nbsp;Jiejie Liao,&nbsp;Xiao Qin","doi":"10.1111/jog.70058","DOIUrl":"10.1111/jog.70058","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study investigates iron metabolism characteristics in patients with ovarian endometriosis (EMs) and infertility.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A case–control study was conducted involving 76 infertility patients treated at Baise People's Hospital from December 2023 to December 2024. Among them, 36 patients with ovarian EMs and infertility were included in the case group, whereas 40 infertile women without EMs constituted the control group. The indices of iron metabolism, including serum iron (SI), transferrin (TRF), soluble transferrin receptor (sTfR), unsaturated iron binding capacity (UIBC), total iron binding capacity (TIBC), and transferrin saturation (TS), were measured and compared between the two groups. Furthermore, the association between iron metabolism levels and the development and progression of EMs was systematically analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The SI level was significantly higher in the study group than in the control group (<i>p</i> &lt; 0.01). Levels of TRF, UIBC, and TIBC were significantly lower in the study group compared to the control group (<i>p</i> &lt; 0.001). No significant differences were observed in sTfR or TS between the two groups (<i>p</i> &gt; 0.05). Receiver operating characteristic curve analysis demonstrated that the combined assessment of SI, TRF, UIBC, and TIBC provided statistically significant diagnostic accuracy for differentiating between the two groups, with corresponding <i>p</i> values less than 0.01.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Abnormal iron metabolism is present in patients with EMs and infertility. Excessive iron accumulation may exacerbate disease progression and influence reproductive prognosis. Modulating iron metabolism could potentially serve as a novel strategy to improve the condition of EMs and pregnancy outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/jog.70058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estradiol regulates MBOAT1-mediated ferroptosis and participates in the progression of endometriosis","authors":"Yu-Qing Fang,&nbsp;Yan-Hui Li,&nbsp;Jing-Yi Li,&nbsp;Xiu-Ping Wang,&nbsp;Han-Ke Zhang,&nbsp;Hua-Jing Wang,&nbsp;Yi Liu,&nbsp;Ling Zhang","doi":"10.1111/jog.70069","DOIUrl":"10.1111/jog.70069","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Endometriosis is an estrogen-dependent disease with unclear pathogenesis. Recent evidence suggests that ferroptosis plays an important role in the development of endometriosis. In this study, we aimed to explore whether membrane-bound O-acyltransferase domain-containing 1 (MBOAT1) is a key factor by which estradiol (E2) regulates ferroptosis in endometriosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The expression of estrogen receptors (ESR1 and ESR2) and MBOAT1 was examined by western blotting in endometrium and primary endometrial stromal cells (ESCs). We measured iron content, MDA, and GSH levels using corresponding assay kits and assessed the level of ROS by flow cytometry to evaluate ferroptosis. We treated primary ESCs and human ESCs (T HESCs) with or without RSL3, E2, and an estrogen receptor inhibitor, fulvestrant (Ful), to verify the regulatory relationship between E2 and ferroptosis. In addition, endometriosis model mice were constructed and treated with an intraperitoneal injection of 5 mg/kg Ful once a day for 2 weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Ectopic ESCs (EESCs) showed increased expression of ESR1, ESR2, and MBOAT1. Meanwhile, EESCs demonstrated resistance to ferroptosis compared with normal ESCs (NESCs). Compared with NESCs, EESCs showed significant resistance to RSL3-induced ferroptosis. E2 could up-regulate the expression of MBOAT1 and alleviate RSL3-induced ferroptosis in NESCs, while Ful could down-regulate the expression of MBOAT1 and accelerate RSL3-induced ferroptosis in EESCs. Furthermore, Ful treatment significantly decreased the number and size of ectopic lesions in endometriosis mice by promoting ferroptosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>E2 affected ferroptosis by regulating the expression of MBOAT1 and further participated in the progression of endometriosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world clinical outcomes of patients with high-risk endometrial cancer or endometrial carcinosarcoma in England: A retrospective cohort study","authors":"Vimalanand S. Prabhu,&nbsp;Erik Landfeldt,&nbsp;Eleanor Ralphs,&nbsp;Cheryl Teoh,&nbsp;Jess Ridsdale-Smith,&nbsp;Karen Macey,&nbsp;Nikolay Trankov,&nbsp;Alexandrina Lambova,&nbsp;Jasmine Lichfield,&nbsp;Gemma Eminowicz","doi":"10.1111/jog.70042","DOIUrl":"10.1111/jog.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The objectives of this study were to describe patient characteristics and estimate real-world disease-free survival (rwDFS) and overall survival (OS) from initiation of first adjuvant therapy among patients with high-risk endometrial cancer (EC) in England.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a retrospective cohort study based on data from Public Health England's National Cancer Registration and Analysis Service (NCRAS) between 2014 and 2023. Adult women with EC or endometrial carcinosarcoma at high risk of recurrence who received adjuvant therapy within 90 days after surgery were eligible for inclusion. We operationalized rwDFS as time to next treatment or death.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 6036 women (mean age: 67 years; 86% White) were eligible for inclusion, with a mean follow-up of 48 months. During the study period, 45% of patients experienced recurrence and 39% of patients died due to any cause. Median rwDFS and OS from initiation of adjuvant therapy were estimated at 4.56 years (95% CI: 4.14–5.12) and 8.85 years (95% CI: 8.15–9.82), respectively. Estimated 2-year and 5-year probabilities were 0.64 (95% CI: 0.63–0.65) and 0.49 (95% CI: 0.48–0.50) for rwDFS, and 0.78 (95% CI: 0.77–0.79) and 0.60 (95% CI: 0.58–0.61) for OS, respectively. Disease recurrence was associated with a 3.23-fold higher risk of death (<i>p</i> &lt; 0.001). Kendall's <i>τ</i> correlation coefficient between rwDFS and OS was 0.75 (95% CI: 0.69–0.80, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The results from our study underscore the substantial clinical burden and unmet medical need of women with high-risk EC and the validity of rwDFS as a surrogate for OS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/jog.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olaparib maintenance therapy for recurrent adult granulosa cell tumors: A case report","authors":"Haruna Tsukahara,&nbsp;Ichiro Onoyama,&nbsp;Kazuhisa Hachisuga,&nbsp;Hiroshi Yagi,&nbsp;Hideaki Yahata,&nbsp;Kiyoko Kato","doi":"10.1111/jog.70078","DOIUrl":"10.1111/jog.70078","url":null,"abstract":"<p>Poly (ADP-ribose) polymerase inhibitors (PARPi) are now available for advanced or recurrent epithelial ovarian cancer after platinum-based chemotherapy; however, there is little known concerning the use of PARPi for adult granulosa cell tumors (AGCT). A 49-year-old woman, who previously had primary debulking surgery and a second surgery for a first intraperitoneal recurrence, received a surgery for a second intraperitoneal recurrence of AGCT. Although she received paclitaxel–carboplatin combination chemotherapy and a combination of bleomycin, etoposide, and cisplatin after the surgeries for the first and the second recurrences, respectively, the risk of a third recurrence was considered very high due to microscopic peritoneal dissemination. Olaparib administration was initiated based on a <i>FANCA</i> mutation, which results in homologous recombination deficiency. The patient has been recurrence-free for over 4 years since the initiation of olaparib. This case highlights the possibility of using olaparib for AGCT with a homologous recombination gene mutation.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/jog.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responsiveness of the Japanese version of the Pregnancy-Related Anxiety Questionnaire-Revised 2 and its predictive validity for postnatal maternal mental health: A longitudinal study in Japan","authors":"Ritsuko Shirabe,&nbsp;Hiroko Okada,&nbsp;Tsuyoshi Okuhara,&nbsp;Takahiro Kiuchi","doi":"10.1111/jog.70085","DOIUrl":"10.1111/jog.70085","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The extent to which pregnancy-related anxiety predicts postnatal maternal mental health remains unclear. This study aimed to evaluate the responsiveness and predictive validity of the Japanese version of the Pregnancy-Related Anxiety Questionnaire-Revised 2 in identifying women at high risk for postnatal mental health problems.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A longitudinal study recruited 218 Japanese women in early pregnancy from three facilities and followed them through the postpartum period. Participants completed the scale three times (in early, mid-, and late pregnancy). Responsiveness was analyzed using one-way repeated measures Analysis of Variance. At 1 month postpartum, the Parenting Stress Index and the Edinburgh Postnatal Depression Scale assessed parenting stress and depression. Spearman's correlations were calculated between the scale and parenting stress, and Receiver Operating Characteristic curves examined its predictive validity for depression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 211 women were followed up. The scale scores were highest in early pregnancy (<i>p</i> &lt; 0.001). Spearman's correlation coefficients between pregnancy-related anxiety and postnatal parenting stress ranged from 0.34 to 0.43 across the pregnancy stages. Areas under the curve for predicting postnatal depression were 0.74 (early), 0.79 (mid-), and 0.77 (late pregnancy). Based on the set threshold, women with high scale scores had significantly increased relative risks (95% confidence intervals) of postnatal depression: 3.4 (1.4–8.2) (early), 5.2 (2.5–10.7) (mid-), and 6.9 (2.7–18.0) (late pregnancy).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This scale showed good responsiveness and predictive validity, making it a valuable tool for identifying women at risk of postnatal mental health issues and evaluating intervention efficacy in clinical settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/jog.70085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting fetal distress in growth-restricted fetuses: The role of umbilical vein diameter","authors":"Erdal Şeker,&nbsp;Yavuz Çimen,&nbsp;Hasan Süt,&nbsp;Coşkun Ümit,&nbsp;Mustafa Koçar,&nbsp;Gülşah Aynaoğlu Yıldız","doi":"10.1111/jog.70082","DOIUrl":"10.1111/jog.70082","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to evaluate the role of intra-abdominal umbilical vein (FIUV) diameter in predicting fetal distress and the need for emergency cesarean section during labor in fetuses with small-for-gestational-age (SGA) or late-onset fetal growth restriction (late-onset FGR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective study was conducted between March 2021 and January 2022, involving 51 pregnant women with SGA or late-onset FGR delivering at or beyond 37 weeks' gestation. FIUV diameter was measured via transabdominal ultrasonography, and labor outcomes were assessed. Fetuses were monitored continuously, with cesarean delivery performed for category 3 fetal heart rate tracings. Statistical analyses compared FIUV diameter and FIUV/head circumference (HC) ratios between fetuses with and without distress.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 51 participants, 8 (15.7%) required cesarean delivery due to fetal distress. FIUV diameter was significantly smaller in the distress group (5.20 vs. 8.68 mm; <i>p</i> = 0.006), as well as the FIUV/HC ratio (1.60 vs. 2.65; <i>p</i> = 0.004). Receiver operating characteristic analysis showed AUC values of 0.803 for FIUV and 0.814 for FIUV/HC, with sensitivities of 56.8% and specificities of 100% at cutoff values of 6.2 mm and 1.95, respectively. One-minute Apgar scores were lower in the distress group (6.88 vs. 8.23; <i>p</i> = 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>FIUV diameter is a potential predictor of fetal distress in SGA and late-onset FGR fetuses. Larger FIUV diameters may indicate better fetal adaptation, which in turn reduces labor-related complications. These findings suggest a role for FIUV assessment in guiding delivery planning to improve maternal and neonatal outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}