Journal of Obstetrics and Gynaecology Research最新文献

{"title":"Evaluation of Urine Nephrin:Creatine Ratio Longitudinally in Pregnancy for the Detection of Preeclampsia and Kidney Damage in Women With Pre-Existing Diabetes.","authors":"Kewei Zhang, Thushari Indika Alahakoon, Alex Shaw, N Wah Cheung, Vincent W Lee, Suja Padmanabhan","doi":"10.1111/jog.70278","DOIUrl":"10.1111/jog.70278","url":null,"abstract":"<p><strong>Aims: </strong>(i) To evaluate longitudinal changes in urine nephrin to creatinine ratio (NCR) throughout gestation in women with pre-existing diabetes; (ii) To evaluate the association of NCR with diabetic nephropathy and pregnancy outcomes including preeclampsia.</p><p><strong>Methods: </strong>A prospective cohort study of 158 pregnant women with pre-existing diabetes was conducted. Changes in urinary nephrin, protein, albumin and creatinine were assessed serially during pregnancy at four time points. The association with diabetic nephropathy and pregnancy outcomes was investigated by linear mixed effects models. Spearman's rank correlation was used to assess the correlation of NCR with protein/albumin to creatinine ratio (PCR/ACR).</p><p><strong>Results: </strong>NCR increased from early to late pregnancy (p < 0.05); however, there was no significant difference in NCR between those with and without preeclampsia irrespective of gestational age. Women with diabetic nephropathy had 3.48 times greater [1.38-8.77] NCR at 14 weeks compared to those without (p < 0.01), although this was not sustained in late pregnancy. NCR was positively associated with PCR through pregnancy (p < 0.01) and with ACR at 14 and 30 weeks (p < 0.05); however, the associations were weak.</p><p><strong>Conclusions: </strong>While all women with diabetes show a gradual increase in NCR during pregnancy, it was not a useful marker in predicting preeclampsia. However, higher NCR was indicative of kidney damage in the first trimester and could potentially be useful for monitoring diabetic nephropathy.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70278"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Evaluation of Urine Nephrin:Creatine Ratio Longitudinally in Pregnancy for the Detection of Preeclampsia and Kidney Damage in Women With Pre-Existing Diabetes\".","authors":"","doi":"10.1111/jog.70321","DOIUrl":"https://doi.org/10.1111/jog.70321","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70321"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examination of the Effect of Emotional Freedom Technique on Quality of Life and Symptoms in Dysmenorrhea.","authors":"Ayşe Çuvadar, Handan Özcan","doi":"10.1111/jog.70310","DOIUrl":"https://doi.org/10.1111/jog.70310","url":null,"abstract":"<p><strong>Purpose: </strong>The present study aims to evaluate the effectiveness of Emotional Freedom Techniques (EFT) in improving quality of life and alleviating symptoms among women experiencing primary dysmenorrhea.</p><p><strong>Method: </strong>The present study is a randomized and controlled study with a pretest-posttest design. The study sample consists of a total of 65 women calculated by using the G*Power program. Data collection was conducted using a Personal Information Form, Dysmenorrhea Diagnosis Form, Menstruation Symptom Scale, and Quality of Life Scale. The experimental group received two sessions of EFT, each lasting approximately 45-60 min, aimed at reducing negative emotions and promoting positive coping with menstrual pain, while the control group was provided with dysmenorrhea awareness training and informational brochures as part of routine counseling. Statistical analyses were performed using SPSS 26 software.</p><p><strong>Results: </strong>In the EFT group, there was a significant decrease in negative effects/somatic complaints originating from menstrual symptoms and mean total scores, as well as in pain due to dysmenorrhea. Negative effects/somatic complaints from menstruation and general symptoms increased with increasing pain due to dysmenorrhea. There were significant differences in the physical function quality of life parameter in the EFT group.</p><p><strong>Conclusion: </strong>It was determined that EFT reduces pain, alleviates symptoms, and enhances quality of life in women with dysmenorrhea symptoms.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov identifier: NCT06129279.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70310"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Affective Temperament Traits as Predictors of Menopausal Symptom Severity in the Late Menopausal Transition and Early Postmenopause.","authors":"Neşe Hayırlıoğlu, Cemile İlhan","doi":"10.1111/jog.70317","DOIUrl":"https://doi.org/10.1111/jog.70317","url":null,"abstract":"<p><strong>Aim: </strong>This study examined the role of affective temperament traits as stable psychological vulnerability factors for menopausal symptom severity during the late menopausal transition and early postmenopause.</p><p><strong>Methods: </strong>A total of 105 women aged 40-55 years meeting STRAW+10 criteria for stages -1, +1a, or +1b were included. Menopausal symptoms were assessed using the Menopause Rating Scale (MRS), and affective temperaments were evaluated with the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire (TEMPS-A). Correlation analyses and multivariable linear regression models were used to identify independent predictors of menopausal symptom severity.</p><p><strong>Results: </strong>Mean MRS total score was 18.37 ± 8.65, and 59.0% of participants reported severe symptoms. Anxious temperament showed the strongest correlations with somatic (r = 0.470), psychological (r = 0.574), urogenital (r = 0.300), and total MRS scores (r = 0.570; all p < 0.01). In multivariable analyses, anxious temperament independently predicted somatic, psychological, and total symptom scores, while irritable temperament independently predicted urogenital symptoms.</p><p><strong>Conclusions: </strong>Anxious and irritable affective temperaments are significant independent predictors of menopausal symptom severity. Assessing temperament profiles may help identify women at increased risk for heightened symptom perception and support individualized counseling during the menopausal transition.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT06972290.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70317"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Hysteroscopic Evacuation Versus Oral Estrogen-Progestogen Therapy (Femoston) for Retained Products of Conception After Abortion: A Prospective Comparative Study.","authors":"XiaoYan Gong, HongYan Zhong, JiaHui Peng, JiaHao Liao, ShaoXiang Gong, Rong Zhou, XiaoYan Liu","doi":"10.1111/jog.70305","DOIUrl":"https://doi.org/10.1111/jog.70305","url":null,"abstract":"<p><strong>Aim: </strong>To compare the clinical efficacy and safety of hysteroscopic evacuation and oral estrogen-progestogen therapy (Femoston) in the management of retained products of conception (RPOC) after abortion.</p><p><strong>Methods: </strong>This prospective comparative study enrolled 75 women with post-abortion RPOC. Participants were allocated to treatment according to informed preference: 38 received oral Femoston therapy, and 37 underwent hysteroscopic evacuation. Outcomes included duration of vaginal bleeding, time to resumption of menstruation, endometrial thickness after menstrual cleansing, treatment success, and adverse outcomes.</p><p><strong>Results: </strong>Compared with the hysteroscopy group, the Femoston group had shorter vaginal bleeding duration and earlier resumption of menstruation. Endometrial thickness after menstrual cleansing was greater in the Femoston group. The Femoston group also had a lower overall rate of recorded adverse outcomes, including infection and adhesions. Both groups showed clinical improvement in intrauterine residual tissue, while hysteroscopic evacuation achieved a numerically higher immediate clearance rate. However, oral Femoston achieved a comparable overall clinical effect without invasive intervention.</p><p><strong>Conclusion: </strong>Both hysteroscopic evacuation and oral Femoston showed clinical benefit in the management of post-abortion RPOC. In selected clinically stable patients, oral Femoston may be a feasible conservative alternative, associated with shorter bleeding duration, earlier resumption of menses, greater endometrial thickness after treatment, and fewer recorded adverse outcomes. These findings should be interpreted cautiously due to the non-randomized design and limited sample size, and further, larger studies with standardized safety and outcome assessment are needed.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70305"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Diagnostic Strategy for Polycystic Ovary Syndrome Combining Japanese and International Diagnostic Criteria Using Anti-Müllerian Hormone.","authors":"Hiroki Noguchi, Takeshi Iwasa, Akira Iwase, Haruhiko Kanasaki, Fuminori Kimura, Koji Kugu, Kazuki Saito, Tsuyoshi Baba, Tetsuaki Hara, Toshiya Matsuzaki","doi":"10.1111/jog.70326","DOIUrl":"10.1111/jog.70326","url":null,"abstract":"<p><strong>Aim: </strong>We had defined the anti-Müllerian hormone (AMH) cut-off value level 2 aligned with the Rotterdam/International Evidence-based Guideline (IEBG) for the Assessment and Management of polycystic ovary syndrome (PCOS) 2023 criteria. In this study, we evaluated the utility of AMH cut-off value level 2 in patients who could not be diagnosed under the Japan Society of Obstetrics and Gynecology (JSOG) 2024 criteria due to the absence of endocrinological abnormalities and estimated the utility of a new diagnostic approach combining the JSOG 2024 and the Rotterdam/IEBG 2023 criteria.</p><p><strong>Methods: </strong>Through a nationwide survey in Japan, data were collected for 270 patients with irregular menstrual cycles and an antral follicle count of ≥ 10 to assess the new diagnostic approach.</p><p><strong>Results: </strong>Of 270 patients, 213 (78.9%) met the JSOG 2024 criteria due to the presence of endocrinological abnormalities. Of the remaining 57 patients (21.1%) who did not meet the JSOG 2024 criteria, 36 (63.2%) were additionally diagnosed with PCOS under the Rotterdam/IEBG 2023 criteria by applying elevated serum AMH (level 2). Consequently, the diagnostic rate of PCOS increased by 16.9% (obese/overweight: 9.8%, non-obese/overweight: 19.7%), and the overall diagnostic rate reached 92.2%. The diagnostic rate of this new diagnostic approach was significantly higher than that of the JSOG 2024 or the Rotterdam/IEBG 2023 criteria alone. Patients additionally diagnosed by this new diagnostic approach were significantly older and had a higher prevalence of oligomenorrhea and lower prevalence of amenorrhea compared with those diagnosed under the JSOG 2024 criteria.</p><p><strong>Conclusion: </strong>Applying elevated serum AMH (level 2) based on the Rotterdam/IEBG 2023 criteria improved the diagnostic rate of PCOS, particularly in non-obese/overweight patients and relatively older women with milder PCOS phenotypes. This new approach is practical, complementary, and can help overcome limitations of the diagnosis of PCOS and thus expand diagnostic opportunities.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 5","pages":"e70326"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13149773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Carbon Footprint of a Cesarean Section: A Study on Real-Time, Prospectively Collected Data of Disposables, Energy, and Reusables","authors":"Elisabeth Colenbrander,&nbsp;Eva Cohen,&nbsp;Florine de Haes,&nbsp;Niek Sperna Weiland,&nbsp;Wouter Hehenkamp,&nbsp;Dorien Salentijn","doi":"10.1111/jog.70286","DOIUrl":"10.1111/jog.70286","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The healthcare sector, particularly operating rooms, is a major source of greenhouse gas emissions. To reduce this impact, it is important to assess the carbon footprint of medical procedures. The aim of this study was to assess the carbon footprint of a cesarean section, focusing on CO₂-equivalent (CO₂eq) emissions from disposable products, reusable products, and HVAC energy use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective observational study was conducted in a Dutch academic hospital (Feb–Jun 2025). For 50 C-sections, data on type, material, and weight of disposable and reusable products were collected. CO₂eq emissions were estimated using predefined product groups linked to life cycle assessment (LCA) data. HVAC energy use was calculated from procedure time and corresponding LCA data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean CO₂eq emission of a C-section was 33.5 [SD 2.2] kg CO₂eq. Disposable products accounted for the largest share, with a mean contribution of 27.7 [SD 1.5] kg CO₂eq. Among disposable the surgical drapes, sterile gauze pads, and surgical gowns were the highest emitting categories. Energy use during the procedure contributed an average of 3.4 [SD 0.9] kg CO₂eq, while reusable products accounted for 2.4 [SD 0.1] kg CO₂eq. The mean CO₂eq emissions of planned and unplanned (urgency Levels S2 and S3) C-sections were comparable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The CO₂ emissions of a C-section are substantial; disposable products were the highest contributors. Emission reduction could be achieved by minimizing unnecessary utilization of disposables, replacing disposables with reusable items, or by reducing the number of C-sections performed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/jog.70286","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond HER2-Negative: Clinical and Molecular Relevance of HER2-Ultralow Expression in Gynecologic Pathology","authors":"Gunvanti Rathod,&nbsp;Pragnesh Parmar","doi":"10.1111/jog.70277","DOIUrl":"10.1111/jog.70277","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Menopausal Symptoms, Stress Coping Styles, and Quality of Life in Turkish Women: A Cross-Sectional Study","authors":"Sibel Karakoç,&nbsp;Özlem Aşci","doi":"10.1111/jog.70276","DOIUrl":"10.1111/jog.70276","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to examine the relationship between menopausal symptoms, stress coping styles, and quality of life in Turkish women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study was conducted online with 699 women aged 45–59 years. Data were collected using a Personal Information Form, the Menopause Rating Scale (MRS), the Coping Style Scale (CSS), and the Menopause Specific Quality of Life Questionnaire (MENQOL). Descriptive statistics, correlation analyses, and linear regression analyses were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of participants was 50.31 ± 4.22 years, and the mean age at menopause was 48.15 ± 2.76 years. Of the participants, 61.2% were menopausal. The mean MRS score was 15.50 ± 8.10. The most frequently reported symptoms were nervousness (87.1%), physical and mental fatigue (86.6%), and joint and muscle disorders (85.0%). Weak to moderate positive correlations were found between total and subscale MRS scores and MENQOL subscales (<i>r</i> = 0.379–0.680). Increased severity of menopausal symptoms was significantly associated with decreased menopause-related quality of life (<i>B</i> = 0.113, <i>p</i> &lt; 0.001). Self-confident and optimistic coping styles were negatively associated with psychological symptoms, whereas helpless/self-blaming and submissive coping styles showed weak positive associations with all menopausal symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Menopausal symptoms negatively affect women's quality of life. Stress coping styles are associated with the severity and perception of these symptoms. Helpless/self-blaming and submissive coping styles may exacerbate menopausal symptoms, while self-confident and optimistic coping styles may reduce psychological complaints. Interventions aimed at improving stress coping skills may contribute to better quality of life among menopausal women.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “Management of Pregnancies With a History of Venous Thromboembolism: Low-Dose Low-Molecular-Weight Heparin and Low-Dose Acetylsalicylic Acid Prophylaxis”","authors":"Jing Xu,&nbsp;Dongmei Yang","doi":"10.1111/jog.70266","DOIUrl":"10.1111/jog.70266","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"52 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}