The predictive value of triglyceride-glucose index, lipid accumulation product and lipid ratio on metabolic syndrome in polycystic ovary syndrome patients

IF 1.6 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research Pub Date : 2025-04-06 DOI:10.1111/jog.16283

Ning Ma, Xiao-Ning Cui, Na Wang

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引用次数: 0

Abstract

Objectives

To identify reliable indicators to predict the occurrence of metabolic syndrome (MetS) and to provide an effective way to prevent it in polycystic ovary syndrome (PCOS), we explored the relationships between triglyceride-glucose index (Ty-G), lipid accumulation product (LAP), lipid accumulation product ratio, and MetS.

Methods

We detected the relationship between the Ty-G index, LAP, lipid ratio, and incidence of MetS. In addition, we classified the Ty-G index and LAP into tertiles to determine the efficacy of these indicators in predicting the risk of MetS. Finally, the effects of the Ty-G index, LAP, and lipid ratio on the prediction of MetS were evaluated with the receiver operating characteristic (ROC) curve.

Results

Our results indicate that the incidence of MetS was 38% in 134 patients with PCOS, and that the Ty-G index, LAP, and lipid ratio were independent risk factors for MetS. In addition, the incidence of MetS significantly increased with Ty-G index and LAP. The ROC curve showed that the Ty-G index, LAP, and lipid ratio all showed good performance in predicting the occurrence of MetS in PCOS patients, but the Ty-G index had the highest predictive value, with a cut-off value of 8.70.

Conclusions

Our study revealed that the Ty-G index plays an important role in predicting the occurrence of MetS in PCOS patients. In addition, monitoring blood glucose and lipid levels is an effective approach for preventing MetS in PCOS patients clinically regardless of age, and weight management should be strictly implemented in overweight and obese patients to prevent MetS.

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甘油三酯-葡萄糖指数、脂质积累积及脂质比值对多囊卵巢综合征代谢综合征的预测价值

目的为了确定预测代谢综合征（MetS）发生的可靠指标，并为预防多囊卵巢综合征（PCOS）提供有效途径，我们探讨了甘油三酯-葡萄糖指数（Ty-G）、脂质堆积产物（LAP）、脂质堆积产物比值与 MetS 之间的关系。方法我们检测了甘油三酯-葡萄糖指数、脂质堆积产物、脂质堆积产物比率与 MetS 发病率之间的关系。此外，我们还将 Ty-G 指数和 LAP 分为三等分，以确定这些指标在预测 MetS 风险方面的功效。最后，我们用接收器操作特征曲线（ROC）评估了 Ty-G 指数、LAP 和血脂比值对 MetS 的预测效果。结果我们的研究结果表明，在 134 名多囊卵巢综合征患者中，MetS 的发病率为 38%，Ty-G 指数、LAP 和血脂比率是 MetS 的独立风险因素。此外，MetS的发病率随Ty-G指数和LAP的升高而显著增加。ROC 曲线显示，Ty-G 指数、LAP 和血脂比值在预测 PCOS 患者发生 MetS 方面均表现良好，但 Ty-G 指数的预测值最高，临界值为 8.70。结论我们的研究表明，Ty-G 指数在预测 PCOS 患者发生 MetS 方面发挥着重要作用。此外，在临床上，无论年龄大小，监测血糖和血脂水平都是预防 PCOS 患者 MetS 的有效方法，而对于超重和肥胖患者，应严格执行体重管理以预防 MetS。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obstetrics and Gynaecology Research 医学-妇产科学

CiteScore

3.10

自引率

0.00%

发文量

376

审稿时长

3-6 weeks

期刊介绍： The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.