Journal of Nervous and Mental Disease最新文献

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Alcohol Dependence and Quality of Life: Role of Gender and Psychiatric Comorbidities. 酒精依赖和生活质量:性别和精神合并症的作用
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-06-01 Epub Date: 2025-05-05 DOI: 10.1097/NMD.0000000000001830
Zrnka Kovačić Petrović, Tina Peraica, Mirta Blažev, Dragica Kozarić-Kovačić
{"title":"Alcohol Dependence and Quality of Life: Role of Gender and Psychiatric Comorbidities.","authors":"Zrnka Kovačić Petrović, Tina Peraica, Mirta Blažev, Dragica Kozarić-Kovačić","doi":"10.1097/NMD.0000000000001830","DOIUrl":"10.1097/NMD.0000000000001830","url":null,"abstract":"<p><strong>Abstract: </strong>To address the lack of studies on the impact of gender and psychiatric comorbidities on alcohol dependence (AD) and quality of life (QoL), we conducted a cross-sectional study. We compared QoL between 328 men and 86 women with AD, and 215 healthy men and 120 women. Additionally, we examined the association of alcohol-related variables and psychiatric comorbidity with the QoL of men and women with AD while controlling for sociodemographic variables. A structured clinical interview for sociodemographic and alcohol-related variables, Mini International Neuropsychiatric Interview (M.I.N.I.), and World Health Organization QoL (WHOQoL)-BREF scale, was applied. QoL was poorer for AD subjects compared to healthy controls, with no gender differences. Regression analysis showed that the number of hospitalizations and AD with personality disorder predicted poorer QoL for men, whereas AD with depression predicted poorer social relationships for women. These findings suggest the need for gender-differentiated treatment.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"124-133"},"PeriodicalIF":1.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain Effects of Iron Deficiency-Related Pagophagia. 缺铁对脑的影响。
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-06-01 Epub Date: 2025-05-05 DOI: 10.1097/NMD.0000000000001831
Robert Lalonde, Catherine Strazielle
{"title":"Brain Effects of Iron Deficiency-Related Pagophagia.","authors":"Robert Lalonde, Catherine Strazielle","doi":"10.1097/NMD.0000000000001831","DOIUrl":"10.1097/NMD.0000000000001831","url":null,"abstract":"<p><strong>Abstract: </strong>Pagophagia, defined as compulsive ice eating or ice chewing, is a common form of an eating anomaly (pica) caused by iron deficiency and is treated with iron replacement therapy. The physiological characteristics of pagophagia are reviewed. In one study, iron-deficient subjects were deficient in a test of attention, and ice consumption improved the subjects' response time relative to those drinking tepid water, an effect attributed to increased blood perfusion to the brain and heart. Several studies show that cold stimuli applied to the mouth increase blood flow velocity in the middle cerebral artery, increase peripheral blood pressure, and cause bradycardia. It is possible that pagophagia facilitates attention by elevating cerebral blood flow or by providing more oxygen to the brain. More research effort should be paid to the neurobehavioral impact of cold stimuli ingestion in humans and animals.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"140-144"},"PeriodicalIF":1.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introduction to the New "Guidelines for Authors". 新“作者指引”简介。
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-04-01 Epub Date: 2025-04-09 DOI: 10.1097/NMD.0000000000001827
Kimberly A Yonkers
{"title":"Introduction to the New \"Guidelines for Authors\".","authors":"Kimberly A Yonkers","doi":"10.1097/NMD.0000000000001827","DOIUrl":"10.1097/NMD.0000000000001827","url":null,"abstract":"","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"213 4","pages":"91-98"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suicide Attempts in First Episodes of Major Psychiatric Disorders With Psychotic Features. 具有精神病性特征的重大精神障碍首次发作的自杀企图。
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-04-01 DOI: 10.1097/NMD.0000000000001828
Paola Salvatore, Harimandir K Khalsa, Ross J Baldessarini, Mauricio Tohen
{"title":"Suicide Attempts in First Episodes of Major Psychiatric Disorders With Psychotic Features.","authors":"Paola Salvatore, Harimandir K Khalsa, Ross J Baldessarini, Mauricio Tohen","doi":"10.1097/NMD.0000000000001828","DOIUrl":"10.1097/NMD.0000000000001828","url":null,"abstract":"<p><strong>Abstract: </strong>Suicidal behavior is prevalent with first psychotic episodes, but reports of associated factors involve inconsistent findings and emphasis on schizophrenia. We evaluated suicide attempt rates and associated risk factors in 395 first-episode patients with various DSM-5-TR diagnoses with psychotic features, comparing 83 suicidal patients to others. Suicide attempt risk averaged 21.0%, with the final diagnosis ranked as follows: major depression, bipolar I depression, bipolar I mixed features, schizoaffective-depressed, unspecified psychosis, schizophrenia, schizoaffective-bipolar, bipolar I mania, delusional disorder, and none with schizophreniform or brief psychosis. Associated by multivariable modeling were initial recklessness ≥ initial impulsive violence ≥ initial anergy ≥ prior suicide attempt ≥ initial despair ≥ initially homicidal. Risk factors were similar in 36.1% of suicidal cases before and at first episodes. Suicide attempts were prevalent with hospitalized first psychotic episodes: more with major affective disorders or schizoaffective-depression than with schizophrenia or other diagnoses. Notable risk factors included initial reckless, impulsive, angry, and violent behavior, depressive features, anergy, and prolonged prodromes.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"213 4","pages":"108-116"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19-Related Changes in Adolescents' Daily-Life Social Interactions and Psychopathology Symptoms. 与新冠肺炎相关的青少年日常生活社交互动和精神病理症状的变化
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-04-01 Epub Date: 2025-04-09 DOI: 10.1097/NMD.0000000000001826
Robin Achterhof, Inez Myin-Germeys, Eva Bamps, Noëmi Hagemann, Karlijn S F M Hermans, Anu P Hiekkaranta, Julie J Janssens, Aleksandra Lecei, Ginette Lafit, Olivia J Kirtley
{"title":"COVID-19-Related Changes in Adolescents' Daily-Life Social Interactions and Psychopathology Symptoms.","authors":"Robin Achterhof, Inez Myin-Germeys, Eva Bamps, Noëmi Hagemann, Karlijn S F M Hermans, Anu P Hiekkaranta, Julie J Janssens, Aleksandra Lecei, Ginette Lafit, Olivia J Kirtley","doi":"10.1097/NMD.0000000000001826","DOIUrl":"10.1097/NMD.0000000000001826","url":null,"abstract":"<p><strong>Abstract: </strong>The COVID-19 pandemic is believed to have strongly impacted adolescents' mental health through limiting their day-to-day social lives. However, little is known about the role of (social) risk/protective factors and adolescent mental health. Subclinical psychopathology, and risk and protective factors of n = 173 adolescents (T1 mean age = 16.0; 89% girls) were assessed prepandemic and early-pandemic (T1: 2018/2019; T2: May 2020). Daily-life social interactions were assessed in 6-day experience sampling periods. Correcting for age, multilevel analyses revealed declines in general psychopathology and anxiety symptoms; fewer face-to-face social interactions, more online social interactions; and higher-quality face-to-face interactions during the pandemic than before. Negative associations between psychopathology and the quality of face-to-face peer and family interactions were stronger during the pandemic than prepandemic. The results reflect that, early in the pandemic, the mental health impact on adolescents may have been limited. High-quality face-to-face interactions with family and peers seemed particularly powerful in keeping adolescents resilient.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"213 4","pages":"99-107"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of the DRD and OXT Genetic Polymorphisms With Schizophrenia in a Chinese Population. 中国人群中DRD和OXT基因多态性与精神分裂症的关系
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-03-01 Epub Date: 2025-02-24 DOI: 10.1097/NMD.0000000000001824
Jingjing Li, Wen Bi, Mengqiu Xiong, Lubanga Nasifu, Lingyun Zhang, Chengbin Zhu, Bangshun He
{"title":"Association of the DRD and OXT Genetic Polymorphisms With Schizophrenia in a Chinese Population.","authors":"Jingjing Li, Wen Bi, Mengqiu Xiong, Lubanga Nasifu, Lingyun Zhang, Chengbin Zhu, Bangshun He","doi":"10.1097/NMD.0000000000001824","DOIUrl":"10.1097/NMD.0000000000001824","url":null,"abstract":"<p><strong>Abstract: </strong>The polymorphism of dopamine receptor (DRD) and oxytocin (OXT) may be associated with schizophrenia. A case-control study of 248 schizophrenia patients and 236 controls was conducted using the Sequenom MassARRAY platform. The results showed that DRD2 rs1800497 was a heterozygote (AG vs. GG: adjusted odds ratio [OR] = 1.88; 95% confidence interval [CI]: 1.09-3.25) and DRD3 rs7631540 (TC vs. CC: adjusted OR = 0.60; 95% CI: 0.36-1.02) may be associated with an increased risk of developing schizophrenia. In addition, the DRD2 rs1800497 genotype GA showed a reduced risk of schizophrenia in the male subgroup and the late-onset subgroup (>27 years of age). For DRD3 polymorphisms, the rs7631540 TC genotype was associated with schizophrenia in the female subgroup. In OXT polymorphism analysis, rs2740210 codominant CA/AA was a risk factor for schizophrenia in the male and early-onset subgroup (≤27 years old). This study also concluded that OXT rs2740210 codominant CA/AA is associated with schizophrenia.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"71-77"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143492415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations Between Epistemic Trust and the Severity of Personality Disorder: Results From a Study Comparing Patients With Personality Disorder, Anxiety Disorder, and Controls. 认知信任与人格障碍严重程度之间的关系:一项比较人格障碍、焦虑障碍和对照组患者的研究结果
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-03-01 Epub Date: 2025-02-20 DOI: 10.1097/NMD.0000000000001825
Saskia Knapen, Wendy Mensink, Wilma E Swildens, Adriaan W Hoogendoorn, Puck Duits, Joost Hutsebaut, Aartjan T F Beekman
{"title":"Associations Between Epistemic Trust and the Severity of Personality Disorder: Results From a Study Comparing Patients With Personality Disorder, Anxiety Disorder, and Controls.","authors":"Saskia Knapen, Wendy Mensink, Wilma E Swildens, Adriaan W Hoogendoorn, Puck Duits, Joost Hutsebaut, Aartjan T F Beekman","doi":"10.1097/NMD.0000000000001825","DOIUrl":"10.1097/NMD.0000000000001825","url":null,"abstract":"<p><strong>Abstract: </strong>Early childhood adversity may dispose an individual to adopt a rigid and pervasive hypervigilant position toward information coming from others, resulting in high levels of epistemic mistrust (EM), which is supposed to increase the risk of developing psychopathology. A more intrinsic relationship between EM and the development of personality disorders (PDs) is assumed. Although the theory of epistemic trust (ET) is rather novel, it has quickly become widely accepted in the field, despite much empirical evidence. This is the first study investigating the level of ET and associations between ET and PDs among patients with PD, anxiety disorders, and a community sample. Our results demonstrated more severe impairments in ET in patients, and associations found between ET and the severity and types of PDs corroborate the theoretically assumed model. Future research with larger samples and prospective designs is needed to explore further and substantiate the theoretical assumptions about ET.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"65-70"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Group Cognitive Behavioral Therapy on Quality of Life and Psychological Wellbeing of Patients With Parkinson Disease: A Randomized Controlled Trial. 群体认知行为治疗对帕金森病患者生活质量和心理健康的影响:一项随机对照试验。
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-03-01 Epub Date: 2025-02-06 DOI: 10.1097/NMD.0000000000001822
Jale Narimisaei, Mahdi Naeim, Zohreh Nasiri, Shima Imannezhad, Yasaman Mohammadi
{"title":"Effectiveness of Group Cognitive Behavioral Therapy on Quality of Life and Psychological Wellbeing of Patients With Parkinson Disease: A Randomized Controlled Trial.","authors":"Jale Narimisaei, Mahdi Naeim, Zohreh Nasiri, Shima Imannezhad, Yasaman Mohammadi","doi":"10.1097/NMD.0000000000001822","DOIUrl":"10.1097/NMD.0000000000001822","url":null,"abstract":"<p><strong>Abstract: </strong>This study investigates the impact of group cognitive behavioral therapy (CBT) on depression reduction and quality of life improvement among individuals with Parkinson disease. A randomized clinical trial with pretest and posttest measurements involved 90 participants referred to Roozbeh Hospital in Tehran in 2023, who were randomly assigned to either an experimental group ( n = 45) or a control group ( n = 45). The experimental group underwent a 3-month CBT intervention comprising 12 sessions of 90 minutes each. Both groups completed the Beck Depression Inventory and the World Health Organization Quality of Life Questionnaire preintervention and postintervention. Data analysis via multivariate analysis of covariance using SPSS-25 revealed significant improvements in reducing depression and enhancing quality of life in the experimental group compared with the control group ( p ≤ 0.01). These findings indicate that CBT is an effective treatment for reducing depression and improving the quality of life of individuals with Parkinson disease, demonstrating its clinical applicability in therapeutic settings.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"78-81"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Piano Game-Based Learning on the Mental Health of Elderly Individuals. 钢琴游戏学习对老年人心理健康的影响
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-03-01 Epub Date: 2025-02-03 DOI: 10.1097/NMD.0000000000001820
Jie Song, Kean Guan
{"title":"The Impact of Piano Game-Based Learning on the Mental Health of Elderly Individuals.","authors":"Jie Song, Kean Guan","doi":"10.1097/NMD.0000000000001820","DOIUrl":"10.1097/NMD.0000000000001820","url":null,"abstract":"<p><strong>Abstract: </strong>The main research purpose was to investigate the impact of piano courses on the mental health of the elderly. The sample consisted of 30 individuals. The age range of the participants was from 60 to 70 years. For 6 months, the respondents had piano lessons two times a week. One lesson lasted 2 hours and included the development of playing skills and improvisation techniques. The results confirmed the validity of the proposed learning strategy. The Taylor anxiety scale decreased by 19 points. These results showed a decrease of more than half of its original value. The Beck test for depression decreased by 21.5 points. The result shows a decrease two times. The test on the emotional background (the WAM questionnaire) shows an improvement in Well-Being by 3.3 points. In the group of respondents, Activity increased by 3.3 points, and the Mood factor increased by 3.5 points. The direction of further research should be related to the study of the impact of musical practices on various components of the clinical picture of depression and negative emotional states. The results can find practical implementation in the practice of psychotherapeutic work in reducing anxiety and eliminating depression in the elderly in clinics, hospitals, and other medical institutions.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"82-89"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Does the Normalization Process After the COVID-19 Pandemic Affect Patients With Obsessive-Compulsive Disorder? A Longitudinal Study. COVID-19大流行后的正常化过程如何影响强迫症患者?一项纵向研究。
IF 1.6 4区 医学
Journal of Nervous and Mental Disease Pub Date : 2025-02-01 Epub Date: 2025-01-06 DOI: 10.1097/NMD.0000000000001821
Onur Gökçen, Merve Akkuş
{"title":"How Does the Normalization Process After the COVID-19 Pandemic Affect Patients With Obsessive-Compulsive Disorder? A Longitudinal Study.","authors":"Onur Gökçen, Merve Akkuş","doi":"10.1097/NMD.0000000000001821","DOIUrl":"10.1097/NMD.0000000000001821","url":null,"abstract":"<p><strong>Abstract: </strong>This study aims to investigate the effect of the normalization process after the pandemic on obsessive-compulsive disorder (OCD) patients. During the pandemic period, the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Padua Inventory-Washington State University Revision, the Fear of COVID-19 Scale (FCV-19S), and an interview form inquiring sociodemographic characteristics were applied to the participant patients with OCD. During the normalization process, the patients were reevaluated after about 1 year. A significant decrease was found in the patients' FCV-19S and PE-WSUR total scores along with all subscale scores as well as the Y-BOCS scores. The FCV-19S was associated with OCD symptoms both during the pandemic and the normalization period. The final FCV-19S scores of patients with a Y-BOCS score of 12 and under were found to be statistically significantly lower than the others. This study shows that OCD symptom severity and fear of COVID-19 decreased with the normalization process. A decrease in pandemic-related stress and fear of COVID-19 with the normalization process may have positively affected OCD patients.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"50-57"},"PeriodicalIF":1.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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