{"title":"Screen Time and Suicidal Behavior: The Mediating Role of Electronic Bullying Using 2021 Youth Risk Behavior Survey (YRBS) High School Data.","authors":"Margaret L Paul, Enoch K Azasu, Erick Messias","doi":"10.1097/NMD.0000000000001891","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001891","url":null,"abstract":"<p><strong>Aim: </strong>The widespread use of technology raises concerns about the risks associated with elevated screen time among adolescents. The present study explored whether electronic bullying mediates the relationship between screen time and suicidal behavior among high school students.</p><p><strong>Methods: </strong>A cross-sectional analysis was conducted using data from the 2021 Youth Risk Behavior Survey (YRBS). The sample consisted of 17,232 high school students.</p><p><strong>Results: </strong>Of the total, 39.2% of the sample reported high screen time, and 15.9% reported experiencing electronic bullying. Both screen time and electronic bullying were significantly associated with increased sadness/hopelessness, suicidal ideation, suicidal planning, and suicide attempts. Electronic bullying partially mediated the relationship between screen time and all suicidality outcomes.</p><p><strong>Conclusions: </strong>Findings underscore the complex interplay between screen time, electronic bullying, and suicidal behavior among high school students. Furthermore, findings emphasize the need for targeted interventions to mitigate suicide risk in adolescents.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natacha Henriquez, Naz Kapoğlu, Ruth Van der Hallen
{"title":"Supernormal Respondents Report Fewer Immature and Neurotic Defenses Compared to Credible Respondents.","authors":"Natacha Henriquez, Naz Kapoğlu, Ruth Van der Hallen","doi":"10.1097/NMD.0000000000001898","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001898","url":null,"abstract":"<p><strong>Aims: </strong>Defense mechanisms are unconscious strategies used to manage anxiety triggered by unpleasant emotions, thoughts, or circumstances. They are commonly assessed through self-report questionnaires, which are known to be susceptible to response biases. This study examined the extent to which supernormality, an extreme form of positive response bias, affects self-reports of defense mechanisms.</p><p><strong>Methods: </strong>A total of 840 participants completed the Defense Style Questionnaire (DSQ) and the Supernormality Scale-Revised (SS-R). Participants were categorized into a \"supernormal\" group (26.4%) and a \"credible\" group (73.6%) based on their SS-R scores.</p><p><strong>Results: </strong>Supernormal respondents reported significantly lower use of both neurotic and immature defenses as well as lower use of most defense styles, compared with credible respondents.</p><p><strong>Conclusions: </strong>Supernormality seems to be associated with systematic under-reporting of both adaptive and maladaptive defenses. These findings highlight the importance of accounting for response bias when using self-report measures to assess defense mechanisms.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparison of Tardive Dyskinesia With First- and Second-Generation Antipsychotics in Postmarket Surveillance Data.","authors":"Joyce Hanyue Gu, Mark Samarneh","doi":"10.1097/NMD.0000000000001892","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001892","url":null,"abstract":"<p><strong>Introduction: </strong>Tardive dyskinesia (TD) is a known adverse drug reaction (ADR) of first-generation and second-generation antipsychotics. While second-generation antipsychotics are believed to pose a lower TD risk, evidence remains mixed. This study compares TD risk between first- and second-generation antipsychotics using postmarket ADR data.</p><p><strong>Study type: </strong>Observational cross-sectional pharmacovigilance analysis.</p><p><strong>Methods: </strong>We conducted a disproportionality analysis of the FAERS database from 2012 to 2024, calculating the reporting odds ratio (OR) for TD in antipsychotic users. Individual drug ORs were pooled via meta-analysis with stratification by age and sex.</p><p><strong>Results: </strong>Significant variation in TD risk was observed across drugs; second-generation antipsychotics were not uniformly safer than first-generation agents. Stratified analyses revealed further variability by demographic factors. Notably, clozapine exhibited a lower OR compared with other antipsychotics.</p><p><strong>Conclusions: </strong>These findings challenge the assumption of uniformly decreased TD risk of second-generation antipsychotics and underscore the importance of individualized risk assessment when prescribing antipsychotics.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing Integrated Frameworks for Psychiatric Comorbidity.","authors":"Mehmet Sofuoglu, Erin D Reilly","doi":"10.1097/NMD.0000000000001880","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001880","url":null,"abstract":"","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"214 5","pages":"89-90"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maayan Abargil, Dori Rubinstein, Alec Lerner, Erin Basol, Joliza Maynard, Tetiana Davydovska, Ilan Harpaz-Rotem
{"title":"Clinical Boundaries of Trauma: A Conceptual Framework for Navigating Comorbidity and Diagnostic Overlap in PTSD.","authors":"Maayan Abargil, Dori Rubinstein, Alec Lerner, Erin Basol, Joliza Maynard, Tetiana Davydovska, Ilan Harpaz-Rotem","doi":"10.1097/NMD.0000000000001885","DOIUrl":"10.1097/NMD.0000000000001885","url":null,"abstract":"<p><strong>Aim: </strong>Post-traumatic stress disorder (PTSD) rarely occurs in isolation; over 80% of individuals present with comorbid conditions such as depression, anxiety, or substance use disorders. The polythetic DSM-5 structure creates substantial diagnostic heterogeneity, producing thousands of possible symptom combinations. This theoretical paper seeks to demonstrate how trauma-related symptoms transcend diagnostic categories and proposes a mechanism-based framework for improving differential diagnosis and treatment planning.</p><p><strong>Methods: </strong>We review symptom overlap between PTSD and major depressive disorder, borderline personality disorder, prolonged grief disorder, and moral injury, highlighting discrepancies between DSM-5 and ICD-11 conceptualizations.</p><p><strong>Results: </strong>We demonstrate that trauma-related presentations reflect multidimensional suffering involving depression, dissociation, affective dysregulation, identity disturbance, grief, and moral distress. We propose a conceptual, mechanism-based framework organized around four response profiles, fear-based, grief-dominant, dissociative, and moral-injury patterns, that may capture underlying mechanisms more effectively than categorical diagnoses.</p><p><strong>Conclusions: </strong>A mechanism-based approach may refine diagnostic clarity, enhance treatment precision, and better integrate the psychological and somatic dimensions of trauma.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"124-137"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reanne Cunningham Chilton, Lauren M Sippel, Lisanne van Engelen, Rani Hoff
{"title":"Sex and Age Differences in Prevalence of Psychiatric Conditions Comorbid With Substance Use Disorders Among Military Veterans.","authors":"Reanne Cunningham Chilton, Lauren M Sippel, Lisanne van Engelen, Rani Hoff","doi":"10.1097/NMD.0000000000001881","DOIUrl":"10.1097/NMD.0000000000001881","url":null,"abstract":"<p><strong>Aim: </strong>Comorbid substance use disorders (SUDs) and mental health (MH) conditions pose unique challenges to veterans' functioning, quality of life, and treatment.</p><p><strong>Methods: </strong>We characterize comorbidity between SUDs and MH conditions using a sample of 6,872,103 patients enrolled in VA health care. We queried the effect of MH conditions on comorbidity, compared sex and age groups, and characterized the impact of traumatic brain injury (TBI) using logistic regressions.</p><p><strong>Results: </strong>Certain MH conditions are at higher risk of SUDs. There was a small but significant effect of sex and age wherein males and younger veterans were generally more likely to have a comorbid SUD. Those with TBI and TBI plus posttraumatic stress disorder had 1.80 increased odds of having an SUD.</p><p><strong>Conclusions: </strong>Overall, results suggest that comorbid SUDs are highly prevalent among veterans with MH conditions, with some important variability in risk between subgroups that should be taken into account when developing treatment plans and novel interventions.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"138-147"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria Ameral, Amanda K Falcón, Noah R Wolkowicz, Jessica A Patterson, R Ross MacLean
{"title":"Psychiatric Comorbidity in Research on Medications for Opioid Use Disorder: A Systematic Review.","authors":"Victoria Ameral, Amanda K Falcón, Noah R Wolkowicz, Jessica A Patterson, R Ross MacLean","doi":"10.1097/NMD.0000000000001883","DOIUrl":"10.1097/NMD.0000000000001883","url":null,"abstract":"<p><strong>Introduction: </strong>Co-occurring psychiatric conditions are common in opioid use disorder (OUD). This review summarizes findings on the effects of co-occurring conditions on OUD outcomes and changes in psychiatric symptoms during medication treatment for OUD.</p><p><strong>Methods: </strong>The initial search yielded 6,419 articles from PubMed, Embase, Health & Medical Collection, CINAHL, APA PsycINFO, and Medline databases, and 76 of which were eligible for study inclusion. All articles were coded by independent raters, and consensus was used for the final results.</p><p><strong>Results: </strong>Most of the identified studies reported no effect of baseline mental health diagnoses or symptoms on substance use or treatment retention. Studies that examined changes in psychiatric symptoms over time largely reported improvement in mental health during medication treatment.</p><p><strong>Conclusions: </strong>While there is some evidence that mental health symptoms improve during treatment, medications for OUD are likely insufficient on their own for addressing co-occurring mental health conditions.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"214 5","pages":"97-116"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconceptualizing Substance Use Disorders and Comorbidity: Moving Beyond Dual Diagnosis.","authors":"Erin D Reilly, Mehmet Sofuoglu, Megan M Kelly","doi":"10.1097/NMD.0000000000001867","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001867","url":null,"abstract":"<p><p>Since 1952, psychiatry has grappled with the concept of addiction in terms of diagnosis, treatment, and research; this work has been particularly complex given the common co-occurrence of other mental health concerns. Tracing the history of substance use disorder (SUD) comorbidity and exploring related concepts of dual diagnosis, co-occurring disorders, and multimorbidity highlights the necessity for a strong addiction comorbidity framework. In this commentary, we contend that to continue advancing our understanding of addiction comorbidities, a more nuanced and explicit framework is needed. Specifically, one that moves beyond the limitations of dual diagnosis and multimorbidity, and embraces a more integrative, biopsychosocial approach. The DSM offers a critical opportunity for dialogue and development of psychiatric comorbidity frameworks to guide future research, clinical practice, and educational initiatives in the field of addiction and mental health.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":"214 5","pages":"91-93"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychometric Evaluation of the Dimensional Anhedonia Rating Scale (DARS): A Preliminary Study.","authors":"Parker Grant, Marcos Sanches, Tony P George","doi":"10.1097/NMD.0000000000001894","DOIUrl":"10.1097/NMD.0000000000001894","url":null,"abstract":"<p><strong>Aim: </strong>Anhedonia is a transdiagnostic symptom of major depressive disorder (MDD) that is also influenced by substance use, yet the Dimensional Anhedonia Rating Scale (DARS) has only been validated in MDD. This study examined the psychometric properties of the DARS in co-occurring MDD and cannabis use disorder (CUD).</p><p><strong>Methods: </strong>Thirty-five participants completed the DARS, Snaith-Hamilton Pleasure Scale (SHAPS), Hamilton Rating Scale for Depression (HRSD), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Analyses included confirmatory factor analysis, internal consistency, Spearman correlations, group comparisons, and ROC analysis against SHAPS-defined anhedonia.</p><p><strong>Results: </strong>The DARS supported a four-factor (and second-order) structure, demonstrated excellent internal consistency, and showed expected convergent validity (e.g., SHAPS ρ=-.64). ROC analysis indicated good discrimination (AUC=.81) with a Youden-derived threshold of 65 (sensitivity ≈.85; specificity ≈.75).</p><p><strong>Conclusions: </strong>This study provides preliminary evidence of the utility of the DARS in co-occurring MDD and CUD.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":"117-123"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simple to Complex: A Comparison of Clock Drawing Test Scoring Systems.","authors":"Lee Ashendorf, Susanne Withrow","doi":"10.1097/NMD.0000000000001887","DOIUrl":"https://doi.org/10.1097/NMD.0000000000001887","url":null,"abstract":"<p><strong>Aim: </strong>The popularity of the Clock Drawing Test (CDT) is paralleled by the multitude of scoring systems ranging from brief and subjective to complex.</p><p><strong>Methods: </strong>To compare the properties and classification accuracy of different scoring approaches, the CDT was scored using 14 published scoring systems and one simplistic four-point scale using a military veteran sample.</p><p><strong>Results: </strong>Among the scoring approaches, eight displayed acceptable discrimination between profiles classified as cognitively intact versus cognitively impaired based on neuropsychological test scores, with areas under the receiver operating characteristic curve (AUCs)=.709 to .797. Analyses within individual cognitive domains revealed excellent discrimination for the Framingham (visuospatial: AUC=.850, and executive: AUC=.808) and Shulman (language: AUC=.811) scoring approaches.</p><p><strong>Conclusions: </strong>Simpler and even subjective approaches were on par with highly detailed procedures for scoring the CDT. With many scoring approaches being capable of detecting overall impairment, a total score may be most useful as a screening indicator.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}