Meta-analysis of Critical Time Intervention on Clinical and Psychosocial Outcomes.

IF 1.6 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Nervous and Mental Disease Pub Date : 2025-07-07 DOI:10.1097/NMD.0000000000001839

Jack Tsai, Shannon W Schrader, Hind A Beydoun

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引用次数: 0

Abstract

Objective: This brief report describes a limited meta-analysis of controlled studies evaluating critical time intervention (CTI) on select clinical and psychosocial outcomes. Outcome data on 14 domains and 3 broad indices across 8 experimental and quasi-experimental studies were analyzed.

Methods: Random-effect meta-analytic models with pooled standardized mean differences (SMDs) were used.

Results: Groups that received CTI had significantly better outcomes on quality of life (SMD = 0.23, 95% CI: 0.05, 0.41, p = 0.01), homelessness (SMD = -0.20, 95% CI: -0.35, -0.04, p = 0.02), and the Brief Psychiatric Rating Scale Positive Symptom scores (SMD = -0.16, 95% CI: -0.28, -0.05, p = 0.01) than comparison groups at follow-up. CTI also had better outcomes on a created general health outcome index (SMD = -0.28, 95% CI: -0.59, 0.03, z = 1.79, p = 0.07).

Conclusions: CTI has small effect size impacts on several clinical and psychosocial outcomes. The lack of similar measures precluded meta-analysis of other outcomes, such as service engagement.

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关键时间干预对临床和社会心理结果的meta分析。

目的：这篇简短的报告描述了一项有限的荟萃分析，评估关键时间干预（CTI）对选择的临床和社会心理结果的对照研究。分析了8项实验和准实验研究的14个领域和3个宽泛指标的结局数据。方法：采用标准化平均差异（SMDs）随机效应元分析模型。结果：接受CTI治疗组在生活质量（SMD = 0.23, 95% CI: 0.05, 0.41, p = 0.01）、无家可归（SMD = -0.20, 95% CI: -0.35, -0.04, p = 0.02）和简短精神病学评定量表阳性症状评分（SMD = -0.16, 95% CI: -0.28, -0.05, p = 0.01）方面的随访结果明显优于对照组。CTI在创建的一般健康结局指数上也有更好的结果（SMD = -0.28, 95% CI: -0.59, 0.03, z = 1.79, p = 0.07）。结论：CTI对几种临床和社会心理结局的影响较小。由于缺乏类似的测量方法，因此无法对其他结果进行荟萃分析，例如服务参与度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nervous and Mental Disease 医学-精神病学

CiteScore

2.90

自引率

5.30%

发文量

233

审稿时长

3-8 weeks

期刊介绍： The Journal of Nervous and Mental Disease publishes peer-reviewed articles containing new data or ways of reorganizing established knowledge relevant to understanding and modifying human behavior, especially that defined as impaired or diseased, and the context, applications and effects of that knowledge. Our policy is summarized by the slogan, "Behavioral science for clinical practice." We consider articles that include at least one behavioral variable, clear definition of study populations, and replicable research designs. Authors should use the active voice and first person whenever possible.