Journal of Medicinal Plants Research最新文献_第5页

Medicinal plants in oral health and the intergenerational transfer of knowledge: Resilience to cocoa culture in southern Bahia 口腔健康中的药用植物和知识的代际传递:巴伊亚南部可可文化的恢复力

Journal of Medicinal Plants Research Pub Date : 2022-05-31 DOI: 10.5897/jmpr2021.7203

de Oliveira Landi Bolívar, Eduardo Dias Igídio Carlos, di Pace Lucena Brenda, Inácio Ferreira Ferraz Marcelo, Bastos Teixeira Gabriel, O. Aline

引用次数: 0

Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats 龙血树的镇痛、抗炎和催产素活性。Wistar大鼠的树皮水提取物

Journal of Medicinal Plants Research Pub Date : 2022-04-30 DOI: 10.5897/jmpr2021.7140

Gladys Tenywa Mercy, Ganafa Agaba Amon, Olusoji Ajayi Clement, Umba Tolo Casim, Katuura Esther

{"title":"Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats","authors":"Gladys Tenywa Mercy, Ganafa Agaba Amon, Olusoji Ajayi Clement, Umba Tolo Casim, Katuura Esther","doi":"10.5897/jmpr2021.7140","DOIUrl":"https://doi.org/10.5897/jmpr2021.7140","url":null,"abstract":"Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined the analgesic, anti-inflammatory and oxytocic effects of the D. steudneri stem bark aqueous extract. D. steudneri stem bark was collected, authenticated, oven-dried at 45ºC for 48 h, pulverized and extracted using the decoction method. The analgesic effect of the aqueous extract was determined using the acetic acid writhing test, anti-inflammatory activity was determined using paw oedema method while oxytocic activity was determined using abortion and other standard test procedures and were tested at 12.1 24.1 and 48.2 mg/kg. The results of the analgesic study showed that the extract reduced the number of abdominal writhing between 53.51 and 92.40% at 6.02 and 48.2 mg/kg dose, respectively while the standard drug showed a reduction of 36.58% at 10 mg/kg. The anti-inflammatory results showed percentage inhibition of 18.6% (2 h), 22% (2 h) and 18.9% (6 h) at 12.1, 24.1 and 48.2 mg/kg, respectively. The in vivo oxytocic activity showed average time taken for the rats to deliver was between 20.63 h at lowest dose (12.1 mg/kg) and 8.25 h at highest dose (48.0 mg/kg) while Oxytocin the reference drug exhibited, 22 h as the average time taken for delivery. in a set of data was analyzed through the one- way Analysis of Variance and the difference among the means was considered at 95% confidence level using the post-hoc method of Newman-Keuls.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47898823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats 丹参乙醇根提取物对白化大鼠的植物化学分析及安全性评价

Journal of Medicinal Plants Research Pub Date : 2022-04-30 DOI: 10.5897/jmpr2021.7204

O. M. Mwanasiti, A. Florence, C. K. Mutinda, N. Esther

{"title":"Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats","authors":"O. M. Mwanasiti, A. Florence, C. K. Mutinda, N. Esther","doi":"10.5897/jmpr2021.7204","DOIUrl":"https://doi.org/10.5897/jmpr2021.7204","url":null,"abstract":"Erythrina sacleuxii , one of five Erythrina species found in Kenya, is a stiffly multi-branched deciduous tree reported to have antiplasmodial, antifungal, anti-bacterial and anti-cancer activities. This study aimed at evaluating acute and sub-acute oral toxicity of E. sacleuxii roots ethanolic extract. Phytochemical analysis was conducted on Fourier transform infrared spectroscopy and Gas Chromatography-Mass Spectrometer. For acute and sub-acute toxicity studies 16 male rats n=4/group were used. The control group received 2% DMSO while treatment groups received 400, 1200 and 2400 mg/kg single dose (acute toxicity assay) and repeated for 14 days in subacute toxicity assay. Histopathological, serum biochemistry and hematological tests were analyzed. The results of FT-IR analysis recorded 12 dominant peaks, confirming availability of N-H, C-N, -C=C-, C-H, S=O, C-O and C-C functional groups. GC-MS analysis revealed presence of 17 bioactive phytochemicals mainly terpenoids and phenols. No toxic effect, organ toxicity or death was recorded in acute toxicity assay. In the subacute toxicity investigation, rats' behavior, gross pathology, and hematological parameters showed no significant changes. Biochemical analysis indicated an increase in alkaline phosphatase from 147 U/L at 400 mg/kg to 164 U/L at 2400 mg/kg however this was not statistically significant and no mortality was recorded. In comparison to the negative control, treatment groups’ gross and histopathology of livers and kidneys had no significant difference. These results demonstrate that 80% ethanolic extract of E. sacleuxii roots has no severe effects in both acute and subacute study. However, sub-chronic and chronic toxicity studies are necessary for further validation. ,","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43520095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro antiproliferative potential of crude extracts from Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines 番木瓜黑籽提取物对前列腺癌症细胞株的体外抗增殖作用

Journal of Medicinal Plants Research Pub Date : 2022-04-30 DOI: 10.5897/jmpr2022.7214

Mcheza Kateihwa Benson, Swai Hulda, Waweru Gathirwa Jeremiah, Sauli Elingarami

{"title":"In vitro antiproliferative potential of crude extracts from \u0000Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines","authors":"Mcheza Kateihwa Benson, Swai Hulda, Waweru Gathirwa Jeremiah, Sauli Elingarami","doi":"10.5897/jmpr2022.7214","DOIUrl":"https://doi.org/10.5897/jmpr2022.7214","url":null,"abstract":"Black seeds from papaya plants are utilized as traditional medicine in African and Asian cultures to improve the functioning of the male reproductive system and management of prostate cancer. This study analyzed the phytochemical composition, antiproliferative activity and cytotoxicity of Carica papaya black seeds against the prostate cancer cells and Vero cells. Phytochemical screening was performed by standard procedures. Methyl tetrazolium bromide (MTT) cell viability assay was used to evaluate the antiproliferative effect of crude extracts in prostate cancer cells against the control. Phytocompounds, namely flavonoids, alkaloids, tannins, terpenoids, glycosides and saponins were found in the crude extracts. All papaya seeds’ extracts had antiproliferative activity towards prostate cancer cells. Ethyl acetate extract was found with higher antiproliferative activity with IC 50 of 3.64 µg/ml. The crude extracts were not toxic towards Vero cells as compared to the control. Isolation and characterization of active compounds from herein crude extracts and papaya black seeds are therefore recommended for future studies.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45437837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Herbal medicine development and compliance to regulatory guidelines in Imo State Nigeria 尼日利亚伊莫州草药开发和遵守监管指南

Journal of Medicinal Plants Research Pub Date : 2022-04-30 DOI: 10.5897/jmpr2021.7152

P. Adigwe, F. P. Builders, N. Ibekwe, Godspower Onavbavba

引用次数: 1

Antioxidant and antihyperlipidemic activities of unique nicotinyl polysaccharide from the green seaweed Ulva pertusa 绿海藻中独特烟碱多糖的抗氧化和降血脂活性

Journal of Medicinal Plants Research Pub Date : 2022-04-30 DOI: 10.5897/jmpr2022.7222

Wang Yuzhou, Chang Xintao, Liu Lin, W. Shaopeng, Qiao Huimin, Yan Fang

引用次数: 0

Brown macroalgae: Promising sources of bioactive products against human herpesviruses 褐藻:抗人类疱疹病毒生物活性产品的有前途的来源

Journal of Medicinal Plants Research Pub Date : 2022-03-31 DOI: 10.5897/jmpr2021.7183

Leonisa Sanchez Nunez Maria, Won-Held Rabelo Vitor, Christina Nunes de Palmer Paixao Izabel, Laneuville Teixeira Valeria

引用次数: 0

Antibiotic potential of a crude ethanol extract from Asplenium serratum L. fern leaves 蕨类植物悬钩子叶粗乙醇提取物的抗菌潜力

Journal of Medicinal Plants Research Pub Date : 2022-03-31 DOI: 10.5897/jmpr2020.7003

Guerra Santos Marcelo, Schuindt Leal Samella, Aguiar-Alves Fabio, Rocha Leandro

引用次数: 0

Flavonoid content and antioxidant potential of leaf extracts of Passiflora setacea cv BRS Prola do Cerrado, a new wild passion fruit cultivar 野生百香果新品种西番莲叶提取物类黄酮含量及抗氧化活性研究

Journal of Medicinal Plants Research Pub Date : 2022-02-28 DOI: 10.5897/jmpr2021.7190

Santos-Tierno Raphaela, Garcia Renata, Fonseca Eduardo, Faleiro Fábio, Moreira Davyson, Pacheco Georgia, Mansur Elisabeth

{"title":"Flavonoid content and antioxidant potential of leaf extracts of Passiflora setacea cv BRS Prola do Cerrado, a new wild passion fruit cultivar","authors":"Santos-Tierno Raphaela, Garcia Renata, Fonseca Eduardo, Faleiro Fábio, Moreira Davyson, Pacheco Georgia, Mansur Elisabeth","doi":"10.5897/jmpr2021.7190","DOIUrl":"https://doi.org/10.5897/jmpr2021.7190","url":null,"abstract":"Passiflora setacea D.C. is a wild species native to the Brazilian Cerrado, with agronomic and medicinal potentials. The cultivar BRS Pérola do Cerrado is the first registered and protected cultivar of a wild Passiflora and has become an alternative to the passion fruit market due to its desirable characteristics for food, ornamental and pharmaceutic industries. Since plant tissue culture techniques are considered important tools for large-scale production of plants and bioactive compounds, the goal of this work was to evaluate the flavonoid content and the antioxidant potential of hydroethanolic leaf extracts from in vivo and micropropagated plants of this new cultivar. Phytochemical analysis was performed by HPLCUV-ESI-MS/TOF. Antioxidant activity was evaluated by the DPPH and the iron-chelating assays. The activities of antioxidant enzymes catalase, superoxide dismutase and ascorbate peroxidase (CAT, SOD and APX) were also determined. Two di-C-glucosyl flavonoids derivatives from apigenin were registered as major constituents in both leaf extracts analyzed and were identified as vicenin-2 and schaftoside. Despite the low antioxidant potential observed by the DPPH assay, leaf extracts from both in vivo and micropropagated plants showed high chelating capacity. Although no differences in the activity of SOD and CAT were observed, the specific activity of APX was increased in leaf extracts of micropropagated plants. These results suggest that in vitro plants can be used as an alternative for flavonoid production from cultivar BRS Pérola do Cerrado.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42777757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant Kalahari沙漠适应植物原驼峰内生放线菌的抗氧化和DNA损伤保护活性

Journal of Medicinal Plants Research Pub Date : 2022-02-28 DOI: 10.5897/jmpr2021.7175

Elizabeth Lang Magdalena, Sibanda Timothy, Louw Stefan, Damascène Uzabakiriho Jean

{"title":"Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant","authors":"Elizabeth Lang Magdalena, Sibanda Timothy, Louw Stefan, Damascène Uzabakiriho Jean","doi":"10.5897/jmpr2021.7175","DOIUrl":"https://doi.org/10.5897/jmpr2021.7175","url":null,"abstract":"Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with medicinal plants, are one understudied source. The goal of this study was to investigate whether the secondary metabolites of endophytic actinobacteria isolated from Harpagophytum procumbens, commonly known as the Devil's claw, have antioxidant and DNA damage protective properties. H. procumbens secondary tubers were collected from the Khomas and Hardap regions of Namibia, yielding a total of 23 isolated actinobacteria. The identities of the actinobacterial isolates were determined by sequencing the 16S rRNA gene. This revealed 6 families affiliated to 7 genera that included the dominant Streptomyces genus (57%) whereas rare genera (Agromyces, Nocardiopsis, Rubrobacter, Patulibacter, Rhodococcus, Curtobacterium) and 2 unidentified strains accounted for 43%. The antioxidant results revealed that the ethyl acetate extracts of Streptomyces species strain A36, had the highest phenolic content of 1.993 ± 0.004 and total antioxidant activity of 0.258 ± 0.001. Meanwhile, extracts from Streptomyces spp. strain B12, had the highest radical scavenging activity of 95% at 0.1 mg·mL -1 while B43, an unidentified actinobacterium, had the highest total reducing power of 0.849 ± 0.003. In addition, 61% of extracts showed the ability to protect DNA from damage when exposed to hydrogen peroxide. None of the samples contained terpenoids, while 13 (72%) contain alkaloids, 17 (94%) contain phenols and 8 (44%) contained flavonoids. The present study concludes that endophytic actinobacteria associated with H. procumbens are a potential source of bioactive compounds with pharmacological properties.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42959652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1