Journal of Medicinal Plants Research最新文献

筛选
英文 中文
Productivity and picroside contents of Picrorhiza kurroa Royle ex Benth. cultivated at multi-locations in Uttarakhand, India 印度北阿坎德邦多地栽培的 Picrorhiza kurroa Royle ex Benth.的生产力和苦苣甙含量
Journal of Medicinal Plants Research Pub Date : 2024-03-31 DOI: 10.5897/jmpr2023.7294
C. P. Kuniyal, Rakesh Bisht
{"title":"Productivity and picroside contents of Picrorhiza kurroa Royle ex Benth. cultivated at multi-locations in Uttarakhand, India","authors":"C. P. Kuniyal, Rakesh Bisht","doi":"10.5897/jmpr2023.7294","DOIUrl":"https://doi.org/10.5897/jmpr2023.7294","url":null,"abstract":"Cultivation is cost effective for conservation and sustainable supply of rare and high value medicinal plants. Assessment of productivity and quality testing validates cultivation and improves trade prospective. Picrorhiza kurroa is a recently domesticated Himalayan medicinal herb. Despite, specific habitat preference above 3000 m in natural habitats, P. kurroa is cultivated successfully below 3000 m under diverse cultivation conditions. In addition to roots/rhizomes, the leaves of P. kurroa are known to contain picrosides (I & II). Therefore, it is inevitable to assess production (roots/rhizomes and leaves), and picroside content (in roots/rhizomes and leaves) of cultivated P. kurroa . A total 12 locations having different age group crop were selected for assessing the production of roots/rhizomes and leaves, and HPLC method was used for estimation of picrosides (I & II) content. Production of roots/rhizomes and leaves (on dry weight basis) of less than two years old crop was 1146.67±95.04 to 1583.33±420.63kg/ha and 1146.67±298.72 to 1396.67±110.15kg/ha respectively. Crop having more than two years, but less than three years age, produced 1760.00±79.37 to 2316.67±330.05 kg/ha roots/rhizomes and 1256.67±11.55 to 2180.00±208.81 kg/ha leaves. Productivity of roots/rhizomes and leaves was 2996.67±90.18 to 3546.67±173.88 kg/ha and 3046.67±56.86 to 3423.33±299.56 kg/ha, respectively for the crop that has completed three years. Irrespective of age of crop and variability in cultivation conditions, picroside I content in roots/rhizomes was from 0.54 to 2.43%, while it was 1.42 to 4.42% in leaves. Picroside II content was from 4.72 to 8.62% in root/rhizomes and from 1.93 to 7.03% in leaves. Production of roots/rhizomes and leaves of P. kurroa under cultivation ( ex-situ) is encouraging and based on picroside content in different plant parts, the quality of cultivated P. kurroa is comparable to naturally growing ( in-situ ) plants.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140358643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive evaluation of antiacne properties: HPLC analysis of crude extract from Aloe buettneri leaves against Cutibacterium acnes-induced acne 抗痤疮特性的综合评估:高效液相色谱法分析芦荟叶粗提取物对痤疮杆菌诱发的痤疮的作用
Journal of Medicinal Plants Research Pub Date : 2024-01-31 DOI: 10.5897/jmpr2023.7331
Dermane Affo, Kombate Bignoate, Metowogo Kossi, Eklu-Gadegbeku Kwashie
{"title":"Comprehensive evaluation of antiacne properties: HPLC analysis of crude extract from Aloe buettneri leaves against Cutibacterium acnes-induced acne","authors":"Dermane Affo, Kombate Bignoate, Metowogo Kossi, Eklu-Gadegbeku Kwashie","doi":"10.5897/jmpr2023.7331","DOIUrl":"https://doi.org/10.5897/jmpr2023.7331","url":null,"abstract":"The hydroethanolic extract of Aloe buettneri was assessed for its anti-acne activity in a Cutibacterium acnes -induced acne model in rats as part of this study. Conventional therapies for acne often entail serious side effects. Total phenols, quantified using the Folin-Ciocalteu method, were found to be at a concentration of 16 ± 0.3 mg GAE/g, while total flavonoids, determined using the aluminum chloride method, were measured at 2.83 ± 0.5 mg QE/g. High-performance liquid chromatography (HPLC) techniques identified four polysaccharidic flavonoids in the extract: protocatechuic acid, caffeic acid, homo-orientin, and ferulic acid. In the acne-induced rat model, the disease group exhibited increased ear thickness, rectal temperature, and MDA level, along with a decrease in glutathione level (###p < 0.001). However, significant improvement in these parameters was observed after 12 days of topical treatment (***p < 0.001). The identified molecules in the A. buettneri extract, including protocatechuic acid, caffeic acid, homo-orientin, and ferulic acid, may contribute to the observed anti-acne properties.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"228 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140473895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial activities of the extract of shea tree (Vitellaria paradoxa Gaertn. F.) leaf and bark on some selected clinical pathogens 乳木果树(Vitellaria paradoxa Gaertn. F.)叶和树皮提取物对一些选定临床病原体的抗菌活性
Journal of Medicinal Plants Research Pub Date : 2023-12-31 DOI: 10.5897/jmpr2023.7329
Adelani Adetunde Lawrence, Awo Oliver, Mbelayim Imoro Abdul-Wahab
{"title":"Antimicrobial activities of the extract of shea tree (Vitellaria paradoxa Gaertn. F.) leaf and bark on some selected clinical pathogens","authors":"Adelani Adetunde Lawrence, Awo Oliver, Mbelayim Imoro Abdul-Wahab","doi":"10.5897/jmpr2023.7329","DOIUrl":"https://doi.org/10.5897/jmpr2023.7329","url":null,"abstract":"The use of plants and plant products in the treatment of various ailments has been with humanity since the dawn of time and the potentials of these plants are so enormous that the continuous search for their hidden treasures is more crucial because of the rise in antibiotic resistance. This study was designed to determine the antimicrobial activities of the shea tree ( Vitellaria paradoxa ) extracts against some selected clinical pathogens. Five pathogenic microorganisms, namely, Bacillus cereus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli, and Salmonella typhi were used to assess the efficacy of the extracts. The antimicrobial effects of the extracts were examined by the agar well diffusion method on the selected pathogens using Mueller Hinton agar. The control used was Amoxicillin antibiotic. The results revealed that both the bark and crude leaf extracts had antibacterial effect on each of the clinical isolates. The crude leaf extract showed the lowest activity against all tested microorganisms, while the bark extract showed the highest. The bark extract recorded the highest zone of inhibition of 15.5 mm. The study recommends shea tree extracts as a potential source of antibiotic substance against infections caused by the tested microorganisms.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"62 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemicals properties of Carica papaya Linn seeds essential oil and their antifungal and antibacterial activities 林木瓜籽精油的植物化学特性及其抗真菌和抗细菌活性
Journal of Medicinal Plants Research Pub Date : 2023-11-30 DOI: 10.5897/jmpr2023.7321
Assetou Ouedraogo, P. A. Nikiéma, Gerard Josias Yameogo, P. B. Sourabie, Belinda Ramata Hafouo Bassave, Soumaïla Konate, Marguerite E. M. Nikiema, Ouéogo Nikiema, Wendinmi Bertrand Florent Goumbri, Nicolas Barro
{"title":"Phytochemicals properties of Carica papaya Linn seeds essential oil and their antifungal and antibacterial activities","authors":"Assetou Ouedraogo, P. A. Nikiéma, Gerard Josias Yameogo, P. B. Sourabie, Belinda Ramata Hafouo Bassave, Soumaïla Konate, Marguerite E. M. Nikiema, Ouéogo Nikiema, Wendinmi Bertrand Florent Goumbri, Nicolas Barro","doi":"10.5897/jmpr2023.7321","DOIUrl":"https://doi.org/10.5897/jmpr2023.7321","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139198131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genipa americana fruit ethanolic extract in the control of environmental infecting agents 美洲玄参果乙醇提取物在控制环境感染病原体中的作用
Journal of Medicinal Plants Research Pub Date : 2023-11-30 DOI: 10.5897/jmpr2022.7271
Ohana Sousa Abreu Paloma, Pereira De Souza Eanes, Eduarda Costa Silva Luiza, Ely Araujo Oliveira Mariana, Faustino De Oliveira Fernando, Aparecida de Oliveira Rosilene, Rocha Gadelha Sandra, Pacheco Silveira Martins Da Mata Camila, Neves da Hora Raynah, Debortoli de Carvalho Luciana, Oliveira da Conceicao Aline
{"title":"Genipa americana fruit ethanolic extract in the control of environmental infecting agents","authors":"Ohana Sousa Abreu Paloma, Pereira De Souza Eanes, Eduarda Costa Silva Luiza, Ely Araujo Oliveira Mariana, Faustino De Oliveira Fernando, Aparecida de Oliveira Rosilene, Rocha Gadelha Sandra, Pacheco Silveira Martins Da Mata Camila, Neves da Hora Raynah, Debortoli de Carvalho Luciana, Oliveira da Conceicao Aline","doi":"10.5897/jmpr2022.7271","DOIUrl":"https://doi.org/10.5897/jmpr2022.7271","url":null,"abstract":"The choice of substances that are not harmful to man and the environment is a priority in the production of sanitizing products. The aim of this study was to evaluate the disinfectant action and biofilm biomass reduction of the ethanolic extract of Genipa americana fruit. The extract disinfectant efficacy was assessed by modified Kelsey-Sykes, solid surface, and use-dilution methods. Also, the ability of the extract to disrupt biofilm mass was evaluated. Standard disinfectants and Gentamicin were used as control. Escherichia coli , Pseudomonas aeruginosa , Staphylococcus aureus , MRSA and MLSB Staphylococcus hominis and Staphylococcus haemolyticus and Staphylococcus species were used as infective and biofilm-forming microorganisms. G. americana fruit extract was not as effective as C12-C14 and BCB, however, it was more effective over Staphylococcus bacteria than 70% alcohol on stainless steel surface for a shorter exposure time. The extract did not show the ability to remove adhered P. aeruginosa nor to disrupt the mature biofilm. The ethanolic extract of genipap did not show optimal disinfectant action in the simulated critical environment; however, considering the reported antimicrobial action of this extract, more studies should be considered to find the best formula to improve this extract's disinfectant efficacy.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139202545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnobotanical studies in Irans rangelands 伊朗牧场人种植物学研究
Journal of Medicinal Plants Research Pub Date : 2023-11-30 DOI: 10.5897/jmpr2023.7326
Heirany Amirreza, Kolahi Mahdi
{"title":"Ethnobotanical studies in Irans rangelands","authors":"Heirany Amirreza, Kolahi Mahdi","doi":"10.5897/jmpr2023.7326","DOIUrl":"https://doi.org/10.5897/jmpr2023.7326","url":null,"abstract":"Iran’s rich plant biodiversity includes over 8,400 species, of which more than 2,300 possess medicinal properties. The research community comprised scientific documents on ethnobotany published between 2010 and 2022. Keywords related to ethnobotany, rangeland, and Iran were searched in the databases of scientific journals. All articles were downloaded and read. The collected data were analyzed using Excel. This study focuses on ethnobotanical research conducted in Iran’s rangelands and documents 158 ethnomedicinal species from 62 families. The most represented families were Lamiaceae, Asteraceae, Apiaceae, and Fabaceae. Leaves were the most commonly used plant part, and the dominant life forms observed were hemicryptophytes, therophytes, and phanerophytes. Female professors showed a higher interest in studying ethnobotanical knowledge compared to males. Despite a decline in traditional knowledge among the younger generation, Iranian residents continue to use plants for medicinal purposes. Further research is needed to identify additional species and conduct phytochemical and pharmacological studies, particularly for high-value plants. Evaluating efficacy and safety is crucial, with a priority on bioassay and toxicity studies. Understanding and preserving Iran’s rich ethnobotanical heritage is important for the sustainable use of medicinal plants .","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"259 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139204213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicinal plants diversity at King Salman Bin Abdulaziz Royal Natural Reserve in Saudi Arabia and their conservation management 沙特阿拉伯萨勒曼-本-阿卜杜勒阿齐兹国王皇家自然保护区的药用植物多样性及其保护管理
Journal of Medicinal Plants Research Pub Date : 2023-11-30 DOI: 10.5897/jmpr2023.7317
A. S. Hatem, Khafaga Tamer, Al-Hassan Hamdan, Alqahtani Shaykah
{"title":"Medicinal plants diversity at King Salman Bin Abdulaziz Royal Natural Reserve in Saudi Arabia and their conservation management","authors":"A. S. Hatem, Khafaga Tamer, Al-Hassan Hamdan, Alqahtani Shaykah","doi":"10.5897/jmpr2023.7317","DOIUrl":"https://doi.org/10.5897/jmpr2023.7317","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139203788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of tetrahydrocannabinol and cannabidiol contents in Cannabis sativa L. samples in Togo using gas chromatography-mass spectrometry 气相色谱-质谱法测定多哥大麻样品中四氢大麻酚和大麻二酚的含量
Journal of Medicinal Plants Research Pub Date : 2023-10-31 DOI: 10.5897/jmpr2023.7313
Eloh Kodjo, Alfa Komi, Simalou Oudjaniyobi, Chris Janiba SANVEE Sabrina, Bakaï Marie-France, Kagnou Hèzouwè, Caboni Pierluigi
{"title":"Determination of tetrahydrocannabinol and cannabidiol contents in Cannabis sativa L. samples in Togo using gas chromatography-mass spectrometry","authors":"Eloh Kodjo, Alfa Komi, Simalou Oudjaniyobi, Chris Janiba SANVEE Sabrina, Bakaï Marie-France, Kagnou Hèzouwè, Caboni Pierluigi","doi":"10.5897/jmpr2023.7313","DOIUrl":"https://doi.org/10.5897/jmpr2023.7313","url":null,"abstract":"Cannabis sativa L. is a widely used recreational drug in Togo, especially among young people. However, little is known about its chemical composition in Sub-Saharan Africa, and specifically in Togo. This study aimed to determine the levels of phytocannabinoids, specifically &Delta;9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in cannabis samples collected from various towns in Togo using gas chromatography coupled to mass spectrometry (GC-MS). Thirteen cannabis samples were extracted with hexane using maceration and ultrasound to isolate phytocannabinoids, and a quick 24-min gas chromatographic separation method was used to analyse the extracts. THC, CBD, and cannabinol (CBN) were the major components identified in the samples. THC content ranged from 37.73&plusmn;0.31 to 87.9&plusmn;1.30% for maceration and from 39.09&plusmn;2.17 to 84.54&plusmn;0.80% for sonication, while CBD content varied from 1.36&plusmn;0.27 to 4.07&plusmn;0.23% for maceration and from 1.79&plusmn;0.12 to 5.03&plusmn;0.90% for sonication. These results indicate that cannabis consumed in Togo has high concentrations of THC and that maceration and sonication is more likely to extract THC and CBD, respectively. The findings could provide important information for the authorities in Togo to assess the extent of THC exposure among cannabis consumers in the country. Key words: Cannabis sativa L., cannabidiol, phytocannabinoids, tetrahydrocannabinol, solvent extraction.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"128 15","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135765517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive liquid chromatography-mass spectrometry-based metabolomic analysis of Moringa oleifera seeds 基于液相色谱-质谱的辣木种子代谢组学综合分析
Journal of Medicinal Plants Research Pub Date : 2023-09-30 DOI: 10.5897/jmpr2023.7318
Oluwayemisi Juliannah Famurewa, Yarkasuwa Chindo Istifanus, Adamu Mahmoud Auwal
{"title":"Comprehensive liquid chromatography-mass spectrometry-based metabolomic analysis of Moringa oleifera seeds","authors":"Oluwayemisi Juliannah Famurewa, Yarkasuwa Chindo Istifanus, Adamu Mahmoud Auwal","doi":"10.5897/jmpr2023.7318","DOIUrl":"https://doi.org/10.5897/jmpr2023.7318","url":null,"abstract":"Moringa oleifera seeds which are less explored and nutriment-rich have attracted scientific interest as the seed kernels contain numerous bioactive components with a variety of traditional uses. Besides its medicinal uses, Moringa oleifera biodiesel has shown remarkable potentiality in conducing to the decrease of greenhouse gases and guaranteeing sustainable supply of energy. In this study, the comprehensive analysis of the M. oleifera seeds metabolome was carried out by generating a Molecular Network (MN) from Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) data to profile the ethyl acetate extract. The dereplication information was then collected by the MN, which then compares the MS/MS spectra of the investigated compounds and groups them into clusters based on their fragmentation route similarities. Therefore, identification of the compounds was conducted based on their full MS and MS/MS spectra obtained in positive ion mode. Through mass spectrometry-based molecular networking a total of 54 metabolites were putatively identified encompassing different classes including coumarins, alkaloids, amino acids, flavonoids, terpenoids, fatty acids, steroids and lipids among others. Thus, the identification highlights that M. oleifera seeds could serve as potential biomarker for new drug discovery and can have a wide variety of applications in food industry. Also, these fatty acids (saturated and unsaturated) suggest that the seed is a good candidate for biodiesel production, since they are fundamental to whether M. oleifera seeds can be used as a biofuel feedstock. Key words: Moringa oleifera seeds, biodiesel, sustainable energy, LC-MS/MS, molecular networking.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136271777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia in Wistar albino rats 野鸭叶及果肉提取物对口服糖负荷性高血糖大鼠血糖水平的影响
Journal of Medicinal Plants Research Pub Date : 2023-09-30 DOI: 10.5897/jmpr2023.7310
J. C. Kyewalabye, J. N. Kasolo, A. Lugaajju, B. Kirenga, C. Batte, A. Lubega, S. Bbosa G.
{"title":"Effect of Canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia in Wistar albino rats","authors":"J. C. Kyewalabye, J. N. Kasolo, A. Lugaajju, B. Kirenga, C. Batte, A. Lubega, S. Bbosa G.","doi":"10.5897/jmpr2023.7310","DOIUrl":"https://doi.org/10.5897/jmpr2023.7310","url":null,"abstract":"Canarium schweinfurthii is a common medicinal plant used as food and medicine in communities of central Uganda. Local communities and herbalists commonly used it in the management of diabetes mellitus type 2 with limited information on its effectiveness.&nbsp; Study assessed the hypoglycemic effect of C. schweinfurthii aqueous and total crude leaf and pulp extracts on blood glucose levels in Wistar albino rats. An experimental based laboratory-based study was conducted on 18 groups each with 6 Wistar albino rats. An oral glucose load of 2.5 mg/kg bwt was used to induce physiological hyperglycemia. Group 1 got 2 mL of distilled water; group 2 received 10 mg/kg bwt of glibenclamide, group 3-18 received varying doses of aqueous and total crude extracts respectively. Blood sugar levels were determined at different time intervals (fasting, time 0, 30, 60, 90, 180, and 240 min) using an automated blood glucose glucometer. Study was approved by relevant IRB. Both extracts exhibited hypoglycemic activity though less than glibenclamide drug since curves were above control drug and distilled water. All extracts of C. schweinfurthii had hypoglycemic effect though it was lower compared to glibenclamide and hence its continued use by the local communities in Central Uganda. Key words: Canarium Schweinfurthii, blood sugar levels, hypoglycemic effect, hyperglycemia.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136271771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信