Journal of Medicinal Plants Research最新文献

{"title":"Chemical composition and antibacterial activity against Escherichia coli of extracts of a common household plant","authors":"Maria K. Kozar, Joanna G. Kondylis, K. Drouvalakis, L. G. Kozar","doi":"10.5897/JMPR2020.7031","DOIUrl":"https://doi.org/10.5897/JMPR2020.7031","url":null,"abstract":"Plants have long been a source for a wide variety of compounds with medicinal properties; of significant interest are plant antimicrobial compounds. Given the continual increase in bacterial resistance, it is imperative that new antimicrobial compounds need to be discovered. The purpose of this study was to screen some common household plants for antibacterial activity, specifically against Escherichia coli. Leaves of 16 different household plants were subjected to methanol-water extraction and the dried extract was analyzed for antibacterial activity using the standard Kirby-Bauer disk diffusion technique. Of all the plants tested, only the Zebra plant (Aphelandra squarrosa) showed a strong antibacterial activity against E. coli. This Zebra plant extract was further analyzed by gas chromatography/mass spectrometry (GC/MS). A variety of known antibacterial compounds including glycerine 46%, phytol 10%, palmitic acid 9%, hydroquinone 6%, linoleic acid 6%, catechol 4% and decanoic acid 3% were shown to be present in the Zebra plant extract along with other compounds whose structure could not be identified at this time. This provides additional avenues for future research especially in the identification of these unknown compounds present in this plant extract which may contribute to its antibacterial activity. \u0000 \u0000 Key words: Chemical composition, antibacterial activity, Aphelandra squarrosa extracts, Escherichia coli.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"15 1","pages":"56-63"},"PeriodicalIF":0.0,"publicationDate":"2021-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44166484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnobotanical study of selected medicinal plants used for the treatment of respiratory diseases in Southern Brazil","authors":"M. S. Borges, M. D. Freitas, P. S. Cardoso, V. C. Zanette, Silvia Dal B o, P. A. Amaral","doi":"10.5897/JMPR2020.6982","DOIUrl":"https://doi.org/10.5897/JMPR2020.6982","url":null,"abstract":"This survey explored the ethnobotanical uses of selected medicinal plants; Adiantum raddianum C. Presl. (Pteridaceae), Lippia alba (Mill.) N. E. Brown (Verbenaceae) and Coronopus didymus (L.) Sm. (Brassicaceae) used for respiratory diseases in Southern Santa Catarina (Brazil). This is timely as the incidence of respiratory disease is increasing in this state. Information was obtained through both interviews using a semi-structured questionnaire administered to 368 people and evaluation of published literature on these plants from scientific peer reviewed journals. The age profile of participants ranged from 20 to over 89 years, with females representing 75% of interviewees. Regarding their use of the medicinal species, 53% reported being users of one of the three plants. Approximately, 52% of users preferred to utilize L. alba, 40% C. didymus and 8% A. raddianum. The primary respiratory diseases reported for use by the plants included   cough, flu or cold, lung disorders, bronchitis and asthma. There was also more scientific literature available to support the use of L. alba for treatment of respiratory diseases. This study contributes to the documentation of the medicinal and popular uses of L. alba, C. didymus and A. raddianum in Southern Brazil, in ways that respect and support their conservation. Further studies are warranted to evaluate the biochemical and pharmacological activities of C. didymus and A. raddianum. \u0000 \u0000 Key words:  medicinal plants, Coronopus didymus, Adiantum raddianum, Lippia alba, respiratory problems, ethnobotanical survey.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"15 1","pages":"22-34"},"PeriodicalIF":0.0,"publicationDate":"2021-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49269726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The study on antioxidant activity of ulvan-calcium derivative","authors":"Xiaoqian Wang, Yuzhou Wan, Lin Liu, Haiting Xu, J. Zou, S. Liang, Chen Yang, Huimin Qi","doi":"10.5897/JMPR2020.7059","DOIUrl":"https://doi.org/10.5897/JMPR2020.7059","url":null,"abstract":"Ulvan is a water-soluble polysaccharide that is extracted from the algae Ulva pertusa (Chlorophyta). In this study, ulvan-calcium derivative (U-calcium) was prepared and calcium content was 5.2%. Ulvan-calcium could effectively scavenge on 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis (3-ethyl-benzothiazolie-6-sulfonic acid) (ABTS), hydroxyl, and superoxide radicals. The inhibition rate on superoxide radicals (•O2-) was 83.14% at 0.2 mg/mL, and the scavenging activity of ABTS and hydroxyl radical (•OH) at 3.0 mg/mL was 58.45 and 43.65%, and that of DPPH radicals at 8.0 mg/mL was 57.37%. All results showed that the antioxidant activity of ulvan-calcium was stronger than that of ulvan. The ulvan-calcium maybe used as an antioxidant to remove ROS and resist excessive oxidative stress. \u0000 \u0000 Key words: Ulvan-calcium, Ulva pertusa, antioxidant activity.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"15 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2021-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49229260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiogenesis-Interfering Potential of Wound Healing Plants in Subintestinal Blood Vessels of Tg(fli1a:EGFP)y1/+Zebrafish Embryos","authors":"D. Mans, Priya Magali, Awinash Sardjoeper","doi":"10.3923/rjmp.2021.7.17","DOIUrl":"https://doi.org/10.3923/rjmp.2021.7.17","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78632590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total Phenolics, Flavonoids and in vitro Antioxidant Properties of Lophira lanceolata TIEGH","authors":"O. CollinsAzubuike, Martha Nneoma Ofo, Matthias Onyebuchi","doi":"10.3923/rjmp.2021.29.35","DOIUrl":"https://doi.org/10.3923/rjmp.2021.29.35","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90603793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical, Acute Toxicity and Tolerance Evaluation of Solanum rugosum (Solanaceae) on Skin and Eye","authors":"B. Calixte, Tapé-Adiko N’dr, A. Aminata, Touré Moriba, Adepo Aholia Jea, Say Venance Ma, Kablan Ahmont Lan, Coulibaly Wacothon K, Kone Bamba Die","doi":"10.3923/rjmp.2021.36.45","DOIUrl":"https://doi.org/10.3923/rjmp.2021.36.45","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"116 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88543881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myrothamnus flabellifolius attenuates streptozotocin-high energy diet-induced type 2 diabetes in male sprague dawley rats","authors":"T. Kwape, P. Chaturvedi, Goabaone Gaobotse, Kabo Masisi, Keagile Bati, R. Majinda","doi":"10.5897/JMPR2020.7033","DOIUrl":"https://doi.org/10.5897/JMPR2020.7033","url":null,"abstract":"Several medicinal plants have anti-diabetic properties and can be considered as an alternative therapy because of their actions which are like those of conventional antidiabetic drugs. In this study, we investigated Myrothamnus flabellifolius (MF) ethanol: water (70:30) extract for its possible anti-diabetic potential in streptozotocin-high energy diet (STZ-HED) induced type 2 diabetes mellitus (T2DM) rats and its possible mechanisms of action. Diabetic rats were divided into MF-50, MF-100, MF200, MF-300, MF-400, and Metformin (MET)-500 groups, where the numbers represent doses in mg.kg.bw that were administered to the groups. Normal (NC) and diabetic (DC) controls were administered distilled water. The animals had their fasting blood glucose levels and body weights determined weekly for 21 days. Blood samples, liver, pancreas, and muscle were collected and used for biochemical and histological examination. Our study showed that MF extract lowered glucose levels, body weight, glycated hemoglobin, thiobarbituric acid reactive substances, serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, Homeostatic model assessment of insulin resistance, and alkaline phosphatase (p<0.05; p<0.01) in T2DM. While adiponectin, catalase, leptin, lipid profile, insulin Homeostatic model of assessment of β cell function, and superoxide dismutase levels were elevated (p<0.05; p<0.01). Furthermore, MF extract preserved both the liver and the islets structure of T2DM rats and enhanced muscle glucose transporter 4 (GLUT 4) expression. M. flabellifolius extract normalized blood glucose and body weight in T2DM. Further investigations are needed to explore other possible mechanisms of action and clinical potential of MF extracts. \u0000 \u0000 Key words: Myrothamnus flabellifolius, T2DM, Lipid profile, blood glucose, oxidative stress, streptozotocin-high energy diet, Sprague dawley rats.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"14 1","pages":"625-637"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5897/JMPR2020.7033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46087314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical Screening and Evaluation of Antibacterial Activities of Root Bark Extracts of Moringa stenopetala","authors":"M. Teshome, L. Adane, Yinebeb Tariku","doi":"10.3923/rjmp.2021.1.6","DOIUrl":"https://doi.org/10.3923/rjmp.2021.1.6","url":null,"abstract":"","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82944637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lavandula angustifolia aqueous extract ameliorates anxiety and depressive-like behaviors in chronic mild stress-treated male rats","authors":"Mir Behrad Aghazadeh Ghadim, A. Neisy, M. Sisakht, Z. Khoshdel","doi":"10.5897/JMPR2020.6989","DOIUrl":"https://doi.org/10.5897/JMPR2020.6989","url":null,"abstract":"The study aims to show the possible anxiolytic and antidepressant-like properties of an oral lavender’s flower aqueous extract (LAE) in chronic mild stress (CMS) model of rats. Test and control rats received LAE (200 or 400 mg/ kg) and distilled water respectively. Tests of Sucrose preference (SP), elevated plus maze (EPM), and open field (OFT) were used to evaluate rats’ behavioral changes.  The percentage of SP in the CMS group was 2.6 times less than that of the unstressed group (p<0.05). However, administration of LAE (200 and 400 mg / kg) increased SP of CMS rats by 2.0 and 3.01 times respectively in comparison to those of the stressed animals. EPM analysis revealed that 5-week CMS exposure significantly reduced the number of entries in open arm (0.8 times) as compared to unstressed rats (6.6 times). LAE (200 and 400 mg / kg) reversed CMS by increasing both the total time spent (1.73 and 1.23% respectively) and the number of entries in open arm (5 and 5.7 times respectively) compared to those related to unstressed group (p< 0.05). CMS decreased the number of entries and time spent in the central zone of OFT. Administration of LAE (200 and 400 mg/ kg) to stressed rats enhanced the total distance traveled respectively by 3.30 and 2.65% than the control rats. Taken together, oral lavender aqueous extracts showed ameliorating effects on the depression and anxiety-related behaviors in rats. \u0000 \u0000 Key words: Depression, lavender, chronic mild stress, anxiety, aqueous extract.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"14 1","pages":"593-603"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5897/JMPR2020.6989","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43777954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory effects of Anadenanthera colubrina (Vell.) Brenan stem bark extract on -glucosidase activity and oxidative stress","authors":"Joaquim da Costa Odelio, dos Santos Barbosa Robson, Mendes Soares Ilsamar, Euripedes de Souza Eber, Fernando A. Gellen Luís, Pedro Pereira P. Lemos João, W. S. A. Raimundo, Lincon B. Montel Adão, Donizeti Ascêncio Sérgio","doi":"10.5897/JMPR2020.7025","DOIUrl":"https://doi.org/10.5897/JMPR2020.7025","url":null,"abstract":"In this study, we investigated the promising potential of Anadenanthera colubrina bark extract (BEAc) as a product to combat diabetes mellitus (DM). We evaluated the inhibitory effects of BEAc on α-glucosidase and the oxidation of biomolecules, as well as its main phytoconstituents. In terms of free radical scavenging, BEAc exhibited a dose-effect relationship. BEAc was more efficient than rutin and butylated hydroxytoluene and similar to ascorbic acid at the same concentrations. Evaluation of the IC50 confirmed the good activity of BEAc compared to positive controls and statistically determined to be equal to ascorbic acid. In in vitro α-glucosidase inhibition studies, BEAc generated 31 times more potent inhibition than acarbose and was dose-dependent at the concentrations tested. Lineweaver-Burk and Michaelis-Menten plots obtained for kinetic analysis showed that BEAc competitively inhibited the α-glucosidase catalyzed reaction. Chemical analysis of BEAc by HPLC revealed that the plant is rich in phenolic compounds and confirmed its capacity to inhibit α-glucosidase. Fourteen compounds were identified by reference to authentic standards: Gallic acid, catechin, syringic acid, chlorogenic acid, p-coumaric acid, naringin, vitexin, rutin, isorhamnetin, hesperidin, myricetin, morin, rosmarinic acid, and quercetin. Thus, this study provides the first evidence of the antidiabetic activity of A. colubrina bark and determines its possible modes of action on carbohydrate metabolism via inhibition of α-glucosidase and the control of biomolecule oxidation. These data support the potential use of this plant for the development of promising multi-target therapy products combining postprandial hyperglycemia control and biomolecule oxidation control. \u0000 \u0000 Key words: Kinetic analysis, phenolic content, diabetes mellitus, oxidation of biomolecules.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"14 1","pages":"583-592"},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5897/JMPR2020.7025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41934880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}