乳木果树(Vitellaria paradoxa Gaertn. F.)叶和树皮提取物对一些选定临床病原体的抗菌活性

Adelani Adetunde Lawrence, Awo Oliver, Mbelayim Imoro Abdul-Wahab
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引用次数: 0

摘要

自古以来,人类就利用植物和植物产品来治疗各种疾病,这些植物的潜力如此巨大,以至于由于抗生素耐药性的增加,不断寻找其隐藏的宝藏变得更加重要。本研究旨在确定牛油果树(Vitellaria paradoxa)提取物对一些选定的临床病原体的抗菌活性。五种病原微生物,即蜡样芽孢杆菌、铜绿假单胞菌、白色念珠菌、大肠杆菌和伤寒沙门氏菌被用来评估提取物的功效。使用穆勒欣顿琼脂,通过琼脂井扩散法检测提取物对所选病原体的抗菌效果。对照组为阿莫西林抗生素。结果表明,树皮和粗叶提取物对每种临床分离菌都有抗菌作用。粗叶提取物对所有测试微生物的活性最低,而树皮提取物的活性最高。树皮提取物的抑菌区最大,为 15.5 毫米。该研究建议将乳油木萃取物作为抗生素物质的潜在来源,以对抗由测试微生物引起的感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antimicrobial activities of the extract of shea tree (Vitellaria paradoxa Gaertn. F.) leaf and bark on some selected clinical pathogens
The use of plants and plant products in the treatment of various ailments has been with humanity since the dawn of time and the potentials of these plants are so enormous that the continuous search for their hidden treasures is more crucial because of the rise in antibiotic resistance. This study was designed to determine the antimicrobial activities of the shea tree ( Vitellaria paradoxa ) extracts against some selected clinical pathogens. Five pathogenic microorganisms, namely, Bacillus cereus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli, and Salmonella typhi were used to assess the efficacy of the extracts. The antimicrobial effects of the extracts were examined by the agar well diffusion method on the selected pathogens using Mueller Hinton agar. The control used was Amoxicillin antibiotic. The results revealed that both the bark and crude leaf extracts had antibacterial effect on each of the clinical isolates. The crude leaf extract showed the lowest activity against all tested microorganisms, while the bark extract showed the highest. The bark extract recorded the highest zone of inhibition of 15.5 mm. The study recommends shea tree extracts as a potential source of antibiotic substance against infections caused by the tested microorganisms.
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4.3 months
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