Brown macroalgae: Promising sources of bioactive products against human herpesviruses

Leonisa Sanchez Nunez Maria, Won-Held Rabelo Vitor, Christina Nunes de Palmer Paixao Izabel, Laneuville Teixeira Valeria
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引用次数: 0

Abstract

Marine brown macroalgae have stood out as important sources of new bioactive products, such as antimicrobial, anticoagulant, anti-inflammatory and antiviral drugs. This study aimed to review the literature on the applications of products derived from brown macroalgae as antiviral agents against human herpesviruses. To date, species of seven distinct orders of brown algae have been studied for this purpose, such as Fucales (19 species), Dictyotales (14 species), Ectocarpales (9 species), Laminariales (2 species), Scytothamnales (1 species), Sphacelariales (1 species) and Tilopteridales (1 species). The products evaluated in this review include extracts, fractions and isolated natural products, mainly terpenoids. Extracts, fractions and isolates of brown algae were evaluated against four viruses: simple herpesviruses types 1 and 2 (HSV-1 and HSV-2), human cytomegalovirus (HCMV) and Epstein–Barr Virus (VEB), also known as human herpesvirus 4 (HHV-4). This review shows products derived from brown macroalgae as potential antiherpetic agents.
褐藻:抗人类疱疹病毒生物活性产品的有前途的来源
海洋褐藻已成为抗菌、抗凝血、抗炎和抗病毒药物等新型生物活性产品的重要来源。本文综述了褐藻衍生产品作为人类疱疹病毒抗病毒药物的研究进展。迄今为止,已经对7个不同目的褐藻进行了研究,如Fucales(19种)、Dictyotales(14种)、Ectocarpales(9种)、Laminariales(2种)、Scytothamnales(1种)、Sphacelariales(1种)和Tilopteridales(1种)。本综述评价的产品包括提取物、馏分和分离的天然产物,主要是萜类化合物。对褐藻提取物、馏分和分离物的抗1型和2型简单疱疹病毒(HSV-1和HSV-2)、人巨细胞病毒(HCMV)和eb病毒(VEB)(也称为人疱疹病毒4 (HHV-4)) 4种病毒进行了评价。本文综述了褐藻衍生产品作为潜在的抗疱疹药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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发文量
25
审稿时长
4.3 months
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