Journal of Medicinal Plants Research最新文献_第4页

Determination of total phenolic and flavonoid content, antioxidant and cytotoxic activity of the methanol extract of Acacia nilotica pods 尼罗Acacia nilotica pod甲醇提取物中总酚、黄酮含量及抗氧化和细胞毒性的测定

Journal of Medicinal Plants Research Pub Date : 2022-12-31 DOI: 10.5897/jmpr2022.7268

Manzo Lawaly Maman, Ikhiri Khalid, Yu Liu

{"title":"Determination of total phenolic and flavonoid content, antioxidant and cytotoxic activity of the methanol extract of Acacia nilotica pods","authors":"Manzo Lawaly Maman, Ikhiri Khalid, Yu Liu","doi":"10.5897/jmpr2022.7268","DOIUrl":"https://doi.org/10.5897/jmpr2022.7268","url":null,"abstract":"Acacia nilotica is a medicinal plant used in Niger republic for the treatment of gastrointestinal diseases. The aim of this study was to investigate total phenolic and flavonoid content, antioxidant and cytotoxic activity of the A. nilotica pods collected from Niger republic. The phytochemical contents were examined by colorimetric methods. Antioxidant activity of the methanol extract was screened using DPPH, ABTS and H 2 O 2 free radical scavenging inhibition assays. Cytotoxicity potential was assessed using the in vitro MTT assay. The phytochemical screening of the plant extract revealed the presence of higher amounts of total phenolic, flavonoid and condensed tannins in the extract. IC 50 values for the scavenging of DPPH, ABTS and H 2 O 2 were found lower though manifesting potential antiradical capacities. The extract showed no cytotoxicity against five different cell line models. Taken together, the present results suggested the therapeutic potential of the methanol extract of A. nilotica pods. Further studies to isolate and characterize the bioactive compounds and to investigate their possible cytotoxic effects in vivo are in view.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43135029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical study and anti-radical activity of extracts from the oil seeds of Desbordesia glaucescens (Engl.)Tiegh. from Gabon 甘露油籽提取物的植物化学研究及抗自由基活性研究。来自加蓬

Journal of Medicinal Plants Research Pub Date : 2022-11-30 DOI: 10.5897/jmpr2021.7207

M’Ella Darina Livia Medza, ép Mezui-Mbeng Marie Andrée N’Negue, Engonga Prosper Edou, L. Mengome, Obiang Nestor Engone, Sophie Aboughe-Angone

{"title":"Phytochemical study and anti-radical activity of extracts from the oil seeds of Desbordesia glaucescens (Engl.)Tiegh. from Gabon","authors":"M’Ella Darina Livia Medza, ép Mezui-Mbeng Marie Andrée N’Negue, Engonga Prosper Edou, L. Mengome, Obiang Nestor Engone, Sophie Aboughe-Angone","doi":"10.5897/jmpr2021.7207","DOIUrl":"https://doi.org/10.5897/jmpr2021.7207","url":null,"abstract":"The report focused on the extraction of oilseeds of Desbordesia glaucescens (Engl.) Tiegh. from Gabon as well as on the phytochemical study and evaluation of the anti-free radical activity of the extracts obtained. The extraction was carried out by cold maceration with solvents of increasing polarities: hexane, tricholroethylene, acetone, ethanol and distilled water. The anti-free radical activity was measured by scavenging the free radical cation of 2,2'-azinobis [3-ethylbenzothiazolin-6-sulfonic acid] (ABTS • +) with gallic acid as the standard antioxidant. Total extraction yields were in the order of 82.31%. Phytochemical tests demonstrated the presence of secondary metabolites of alkaloids, tannins, polyphenolstypes, reducing compounds, free anthracene derivatives, anthraquinones, total sugars, coumarins, free quinones, sterols and terpenes, carotenoids, flavonoids, cardiac glycosides, mucilages, saponins and leucoanthocyanins. The results of the anti-free radical activity showed that the polar extracts were much more anti-free of the free radicals than the non-polar extracts. The aqueous extract was the most active with an IC50 of 10 µg. mL -1 , followed by ethanolic extract with IC50 of 14 µg. mL -1 and acetone extract with IC50 of 150 µg. mL -1 . Cyclohexane and trichlorethylene extracts were more or less inactive. Gallic acid, the standard antioxidant, showed an IC50 of 0.37 µg. mL -1 .","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45584185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethnobotanical study, phytochemical composition and in vitro antioxidant activity of the methanol extracts of thirty-two medicinal plants from Southern Nigeria 尼日利亚南部32种药用植物甲醇提取物的民族植物学研究、植物化学成分及体外抗氧化活性

Journal of Medicinal Plants Research Pub Date : 2022-10-31 DOI: 10.5897/jmpr2022.7258

I. O. Isaac, U. Etesin, E. Nya, E. Ukpong, Ufikairom G. Isotuk, U. J. Ibok

{"title":"Ethnobotanical study, phytochemical composition and in vitro antioxidant activity of the methanol extracts of thirty-two medicinal plants from Southern Nigeria","authors":"I. O. Isaac, U. Etesin, E. Nya, E. Ukpong, Ufikairom G. Isotuk, U. J. Ibok","doi":"10.5897/jmpr2022.7258","DOIUrl":"https://doi.org/10.5897/jmpr2022.7258","url":null,"abstract":"The prevalent disease conditions globally, the detrimental effects, and the resistance of microorganisms to synthetic drugs are really worrisome. Measures to checkmate these situations include researches on the role of medicinal plants in health care delivery. This study is aimed at assessing the antioxidant activities of some medicinal plants normally used for the treatment of various ailments in southern Nigeria and searching for new sources of environmentally benign antioxidants. Thirty-eight medicinal plant extracts were screened for phytochemicals and in vitro antioxidant properties by the diphenyl-1-picrylhydrazyl, nitric oxide, and ferric-reducing power assays. The leaf extract of Chrysophyllum albidum exhibited the highest total phenolics of 348.98±0.941 mgGAE/g, while the lowest concentration was obtained in the fruit exocarp extract of Persea Americana (19.00±1.191 mgGAE/g). The highest and the lowest total flavonoids were observed in the leaf extract of Icacina trichanta (109.59±0.481 mgCE/g) and the seed extract of Persea Americana (1.46±0.000 mgCE/g). Total flavonols were highest in the whole-plant extract of Cleome ciliata (933.90±0.186 mgQUE/g) and lowest in the root extract of Combretum racemosum (63.97±0.121 mgQUE/g). Nine extracts gave the best antioxidant scavenging activity with a percentage DPPH ˃70.00% and an IC50 ˂0.5000 mg/ml. These results suggest that some medicinal plants in southern Nigeria have strong antioxidant scavenging abilities. Further investigation to determine the antioxidant activity of the nine active extracts by in vivo methods, as well as isolation and characterization of these active antioxidant compounds, may enhance the development of new drugs for the treatment of oxidative-stress-related illnesses.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47574927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethnobotanical survey and phytochemical screening of aqueous extracts from Detarium microcarpum Guill. Perr in Mali 细木香水提物的民族植物学调查及植物化学筛选。佩尔在马里

Journal of Medicinal Plants Research Pub Date : 2022-10-31 DOI: 10.5897/jmpr2022.7256

D. N., A. A., B. M., C. S., Cisse M., Togola I., Nick P., T. N.

{"title":"Ethnobotanical survey and phytochemical screening of aqueous extracts from Detarium microcarpum Guill. Perr in Mali","authors":"D. N., A. A., B. M., C. S., Cisse M., Togola I., Nick P., T. N.","doi":"10.5897/jmpr2022.7256","DOIUrl":"https://doi.org/10.5897/jmpr2022.7256","url":null,"abstract":"Detarium microcarpum Guill. & Perr is a tree which belongs to Caesalpiniacea family and can reach up 10 m of height, with a horizontal root system. It is confined to the arid regions of West and Central Africa, where it mainly occurs in savannah. The aim of this work is to collate information on the use of Detarium microcarpum in folk medicine by traditional health practitioners and herbalists. Moreover, a phytochemical screening was carried out on the aqueous extracts from its major organs. The ethnobotanical survey was conducted in three administrative regions of Mali (Koulikoro, Sikasso, and Segou), and in the District of Bamako involving 45 individuals, including 25 women and 20 men. According to the collected information leaf, bark, and root of the plant have therapeutic properties and are known to treat 16 diseases, mainly infections and pains. The phytochemical screening detected numerous secondary metabolites, including alkaloids, polyphenolic compounds, terpenes, quinones, anthraquinones, reducing sugars, amines and saponosides in aqueous extracts from leaf, stem bark and root. These compounds could justify the use of this plant in folk medicine.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46128153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aqueous extracts of Lentinula edodes, Pleurotus pulmonarius, and Pleurotus sajor-caju: Antifungal activity and inhibition of exoenzyme production by Candida albicans 香菇、肺侧耳和杏侧耳水提物的抗真菌活性及对白色念珠菌产外酶的抑制作用

Journal of Medicinal Plants Research Pub Date : 2022-10-31 DOI: 10.5897/jmpr2022.7252

Lüdtke Azevedo Morgana, Lambretch Gonçalves Carolina, Menna Alves Alessandro, N. Caroline, Etges Adriana, Daniela Patricia, G. Rafael

{"title":"Aqueous extracts of Lentinula edodes, Pleurotus pulmonarius, and Pleurotus sajor-caju: Antifungal activity and inhibition of exoenzyme production by Candida albicans","authors":"Lüdtke Azevedo Morgana, Lambretch Gonçalves Carolina, Menna Alves Alessandro, N. Caroline, Etges Adriana, Daniela Patricia, G. Rafael","doi":"10.5897/jmpr2022.7252","DOIUrl":"https://doi.org/10.5897/jmpr2022.7252","url":null,"abstract":"This study was aimed at evaluating the effects of aqueous extracts of Lentinula edodes (SHI) , Pleurotus pulmonarius (PUL), and Pleurotus sajor-caju (PSC) on the growth of eight yeast species and the exoenzyme production by Candida species after exposure to the extracts, which were prepared with the cold extraction methodology and tested against yeasts by the broth microdilution method. Proteinase and phospholipase were produced in vitro with the plate assay method using bovine serum albumin and egg yolk, respectively. The antifungal activity of the filtered mushroom extracts at different dilutions was confirmed against non-albicans Candida and Rhodotorula species. Exposing Candida isolates to extracts significantly reduced phospholipase production (p < 0.001). The antifungal activity against yeasts varied among different mushroom extracts. Moreover, SHI and PUL extracts may modulate the activity of phospholipase produced by Candida albicans . However, further studies are required to evaluate the inhibitory effect and its mechanism, as well as complementary studies with a higher number of samples tested.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43816117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethnopharmacological investigation on Msindzano, a beauty mask used by Comorian women: What plants for what mixtures, for what applications? 科摩罗妇女使用的美容面膜Msindzano的民族药理学调查：什么植物用于什么混合物，用于什么应用？

Journal of Medicinal Plants Research Pub Date : 2022-09-30 DOI: 10.5897/jmpr2020.7053

Hassane Soidrou Said, Y. Radjab, Ahamada Himidi Azali, Msahazi Ahmed, F. Abdellah

引用次数: 0

Piper rivinoides Kunth: A medicinal plant that preserves bioactive chemical substances in its essential oil throughout the seasons 胡椒：一种药用植物，在四季中都能在精油中保存生物活性化学物质

Journal of Medicinal Plants Research Pub Date : 2022-08-31 DOI: 10.5897/jmpr2022.7235

Sales Felisberto Jéssica, Jessé Ramos Ygor, A. George, F. Elsie, Mesquita Marques André, de Lima Moreira Davyson

{"title":"Piper rivinoides Kunth: A medicinal plant that preserves bioactive chemical substances in its essential oil throughout the seasons","authors":"Sales Felisberto Jéssica, Jessé Ramos Ygor, A. George, F. Elsie, Mesquita Marques André, de Lima Moreira Davyson","doi":"10.5897/jmpr2022.7235","DOIUrl":"https://doi.org/10.5897/jmpr2022.7235","url":null,"abstract":"The chemical composition and seasonal variation of essential oils (EO) extracted from the aerial parts of the traditional medicinal plant Piper rivinoides were analyzed using gas chromatography (GC) coupled with mass spectrometry (MS) and GC coupled with flame ionization detector (GC-FID) technique, respectively. The wild plants were collected from two different sites in the Atlantic Forest. The analysis allowed us to identify 96.60 to 99.80% of the EO composition. The major compounds with the highest relative percentage for both specimens, regardless of the season, were the bioactive monoterpenes α-pinene and β-pinene, which ranged from 34.78 (summer) to 53.87% (winter) and from 15.24% (autumn) to 47.71% (winter), respectively. The seasonal stability of the major compounds in the two study specimens throughout the year indicates that the phenological cycle influences biosynthesis more than abiotic factors. This type of chemical phenotypic stability is rarely observed in species belonging to the Piperaceae family, which is characterized by high chemical variability. Furthermore, this stability is favorable, and P. rivinoides has the potential to be a source of bioactive compounds.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46113196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ethno botanical study of medicinal plants used by Baka people in the treatment of erectile dysfunction 巴卡人治疗勃起功能障碍所用药用植物的民族植物学研究

Journal of Medicinal Plants Research Pub Date : 2022-08-31 DOI: 10.5897/jmpr2022.7234

Nana Afiong Natacha, Lagarde Betti Jean, F. Evariste, Tchatat Mathurin, B. Pascal, Ndedy Bile Armand, Oumar Njimbam Farick, Tientcheu Womeni Stéphanie, Mvogo Ottou Patrice, Okale Robert

引用次数: 0

Anti-quorum sensing potential of Ageratum conyzoides L. (Asteraceae) extracts from Burkina Faso 布基纳法索菊科阿格兰提取物的反群体感应电位研究

Journal of Medicinal Plants Research Pub Date : 2022-05-31 DOI: 10.5897/jmpr2021.7216

C. Eli, O. Vincent, Compaoré Moussa, R. Ablassé, Kiendrébéogo Martin

{"title":"Anti-quorum sensing potential of Ageratum conyzoides L. (Asteraceae) extracts from Burkina Faso","authors":"C. Eli, O. Vincent, Compaoré Moussa, R. Ablassé, Kiendrébéogo Martin","doi":"10.5897/jmpr2021.7216","DOIUrl":"https://doi.org/10.5897/jmpr2021.7216","url":null,"abstract":"Pseudomonas aeruginosa causes infections in humans, particularly immune-compromised patients with cystic fibrosis, severe burns, and HIV, resulting in high morbidity and mortality. The pathogenic bacteria, P. aeruginosa, produces virulence factors regulated by the mechanism called quorum sensing system. The aim of this study was to assess the anti-quorum sensing activity of Ageratum conyzoides extracts. Chloroform fraction from hydro-methanolic extract at the sub-inhibitory concentration of 100 µg/mL reduced quorum sensing virulence factors production such as pyocyanin, elastases, and rhamnolipids in P. aeruginosa PAO1 after 8 and 18 h monitoring. Moreover, a significant inhibition in HSL-mediated violacein production on C. violaceum CV026 was recorded after 24 and 48 h monitoring without affecting the bacterial growth. The chloroform fraction was rich in polyphenols and triterpenes, and was found to interact with QS receptors. The regulatory genes ( rhlR and lasR) and downstream genes (RhlA and lasB ) were the most affected, while synthase genes ( lasI and rhlI ) were the least affected. High-performance liquid chromatography with diode-array detection (HPLC-DAD) analysis allowed the identification and quantification of some compounds such as gallic acid, vanillic acid, ellagic acid, sinapic acid, and quercetin. Caffeic acid, rutin, and kaempferol were detected in trace amounts. The presence of these phytochemicals could be responsible for the observed anti-quorum activity. The present study is probably the first attempt to investigate the anti-QS potential of A. conyzoides against P. aeruginosa . These data provide additional scientific evidence to justify the wide use of A. conyzoides in traditional medicine in Burkina Faso.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45413693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethnobotanical and ethno-pharmacological approach to ichthyotoxic plants of Gabon 加蓬鱼类毒性植物的民族植物学和民族药理学方法

Journal of Medicinal Plants Research Pub Date : 2022-05-31 DOI: 10.5897/jmpr2022.7224

Gauthier Mayombo Mouele Ulrich, Attéké Christiane, Kokolo Bertrand, Lendzele Sevidzem Silas, Ibrahim

{"title":"Ethnobotanical and ethno-pharmacological approach to ichthyotoxic plants of Gabon","authors":"Gauthier Mayombo Mouele Ulrich, Attéké Christiane, Kokolo Bertrand, Lendzele Sevidzem Silas, Ibrahim","doi":"10.5897/jmpr2022.7224","DOIUrl":"https://doi.org/10.5897/jmpr2022.7224","url":null,"abstract":"This ethnobotanical and ethno-pharmacological study was conducted to know the plants used in fishing practices and to show their importance in traditional medicine in Gabon. For this study, 100 questionnaires were administered to individuals in the fishing and traditional medical domains. 701 plants belonging to 16 different floristic families, including Fabaceae (41%), Rubiaceae (13%), and Rutaceae (15%) were commonly used. Most of the plants were used for fishing and in traditional medicine. Shrubs and trees such as Tephrosia vogelii , Brenania brieyi , highly recognized by the respondents, were used to treat certain diseases such as the ‘night gunshot’ of witchcraft origin, which modern medicine sometimes comes up against. Diseases such as hemorrhoids, malaria, sinusitis and chicken pox were common. On the one hand, the results obtained constitute a source of essential information that could be used to assess the risks of intoxication in populations that consume fish caught from ichthyotoxic plants. On the other hand, this study would permit the understanding of the Gabonese medicinal flora, and could act as a database for subsequent research in pharmacology.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41935672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1