Journal of Medicinal Plants Research最新文献_第6页

Evaluation of the anxiolytic effects of acute administration of Passiflora alata extract in wistar rats submitted to swimming 急性给药西番莲提取物对游泳大鼠抗焦虑作用的评价

Journal of Medicinal Plants Research Pub Date : 2022-02-28 DOI: 10.5897/jmpr2021.7205

José Airton, Ianara de Souza Greco Annik, Santiago Pereira Renan, Roberto Malfara Wilson, da Silva Soares de Souza Maricelma, Maria Barbalho Sandra, Landgraf Guiguer Élen, Cressoni Araújo Adriano

引用次数: 0

Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria 选定南非药用植物对多种耐药细菌的抗菌、抗群体感应、抗生物膜活性和化学图谱

Journal of Medicinal Plants Research Pub Date : 2022-02-28 DOI: 10.5897/jmpr2021.7192

Tsebang Baloyi Itumeleng, Jesulayomi Adeosun Idowu, Ahmed Yusuf Abdullahi, Cosa Sekelwa

{"title":"Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria","authors":"Tsebang Baloyi Itumeleng, Jesulayomi Adeosun Idowu, Ahmed Yusuf Abdullahi, Cosa Sekelwa","doi":"10.5897/jmpr2021.7192","DOIUrl":"https://doi.org/10.5897/jmpr2021.7192","url":null,"abstract":"South African indigenous plants have been predominantly studied for their antibacterial abilities, overlooking their antipathogenic and antivirulence (also known as antiquorum sensing) potential. Hence, this study explored the selected medicinal plants as possible agents capable of interfering with bacterial growth, quorum sensing and biofilm formation and identified their respective bioactive compounds. Ten medicinal plants were extracted with varied solvents. Melianthus comosus (dichloromethane, aqueous and methanol), Pelargonium sidoides (aqueous) and Vachellia karroo (aqueous and methanol) extracts showed potent minimum inhibitory concentration values ranging from 0.19 to 0.78 mg/ml against the tested bacterial pathogens: Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. Reduced violacein production (up to 38.34%) in Chromobacterium violaceum was noted for Melianthus comosus, Plectranthus ecklonii and Pelargonium sidoides extracts. Treatment of five MDR bacterial pathogens with active extracts for anti-adhesion and biofilm development showed up to 66.34 and 31.82% inhibitory effects, respectively. Chemical characterization of active extracts revealed compounds such as α-D-glucopyranoside, methyl, linalool, octadecanoic acid and hexadecanoic acid. The biological assays validated the tested plant extracts as having antibacterial and antipathogenic potentials that could be used against multidrug resistant bacteria.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48381577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Antiplasmodial activity and phenolic composition of Brazilian Salix humboldtiana Willd. extract and fractions 巴西柳抗疟原虫活性及酚类成分研究。提取物和馏分

Journal of Medicinal Plants Research Pub Date : 2022-02-28 DOI: 10.5897/jmpr2021.7131

Dias Ribeiro Silva Ianna, Fernandes Ramos Uebem, Esquerdo Cerqueira Luciana, Santa Brígida da Silva Andressa, Alves Damasceno Junior Geraldo, Alexandre Carollo Carlos, dos Santos Bastos Ivanildes, Puccinelli Orlandi Patrícia, Markus-Michalczyk Heike, Luiz Ramos Barbosa Wagner

引用次数: 0

Noni essential oil associated with adjuvants in the production of phytoalexins and in the control of soybean anthracnosis 诺丽精油与佐剂在植物抗菌素生产和大豆炭疽病控制中的关联

Journal of Medicinal Plants Research Pub Date : 2022-01-31 DOI: 10.5897/jmpr2021.7154

Pinto e Nose Natalia, Sunti Dalcin Mateus, L. Bruna, Solci Toloy Rodrigo, Souza Carlos Mourao Dalmarcia, Giongo Marcos, Cangussu Alex, Helena da Cruz Araujo Sabrina, Rodrigues dos Santos Gil

引用次数: 3

Ethnobotanical survey of medicinal plants utilized by forest edge communities in southern Sierra Leone 塞拉利昂南部森林边缘社区药用植物的民族植物学调查

Journal of Medicinal Plants Research Pub Date : 2022-01-31 DOI: 10.5897/jmpr2021.7193

Johnny Jonathan, Lebbie Aiah, Wadsworth Richard

{"title":"Ethnobotanical survey of medicinal plants utilized by forest edge communities in southern Sierra Leone","authors":"Johnny Jonathan, Lebbie Aiah, Wadsworth Richard","doi":"10.5897/jmpr2021.7193","DOIUrl":"https://doi.org/10.5897/jmpr2021.7193","url":null,"abstract":"A total of 128 medicinal plant species belonging to 71 genera and 46 families were identified and used to treat 42 human ailments. Euphorbiaceae was the leading family with 14 species, followed by Rubiaceae and Leg-Caesalpiniaceae with 12 and 8 species, respectively. Seven species (Coffea stenophylla, Garcinia afzelii, Mitragyna stipulosa, Irvingia gabonensis, Milicia regia, Nauclea diderrichii and Nesogordonia papaverifera) are of conservation concern. Herbs are the highest followed by shrubs, trees, climbers and epiphytes. Leaves are the most used parts, followed by roots, fruits, stems, flowers, nuts, tubers and seeds. The highest calculated Relative Frequency of Citations Index (RFC) was for Musa sapientum, followed by Zingiber officinale, Anisophyllea laurina, Cola nitida, Nauclea latifolia, Tetracera potatoria Allophylus africanus, Cassia sieberiana and Termitomyces microcarpus. The highest Use Value index (UV) was calculated for Cola nitida (1.9) followed by Nauclea latifolia (1.56), Zingiber officinale (1.55) Ficus exasperata and Tetracera potatoria (1.44) respectively. Medicinal plants knowledge is strongly associated with the elderly in secret societies which are structured along gender lines. Plant use for medicinal reason actually addresses a significant part of the way of life and customs of the people living in this area and other rural locations in Sierra Leone.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44642830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Optimized flow cytometric protocol and genome size estimation of Sabah snake grass (Clinacanthus nutans) 沙巴蛇草（Clinacanthus nutans）流式细胞仪优化方案和基因组大小估计

Journal of Medicinal Plants Research Pub Date : 2021-12-31 DOI: 10.5897/jmpr2021.7162

Kandaiah Vidhyaini, Singaram Nallammai, Isparan Kandasamy Kodi

{"title":"Optimized flow cytometric protocol and genome size estimation of Sabah snake grass (Clinacanthus nutans)","authors":"Kandaiah Vidhyaini, Singaram Nallammai, Isparan Kandasamy Kodi","doi":"10.5897/jmpr2021.7162","DOIUrl":"https://doi.org/10.5897/jmpr2021.7162","url":null,"abstract":"Clinacanthus nutans is an economically important medicinal plant that can be found grown in many countries in the Asian region. Useful medicine properties such as anti-cancer, anti-bacteria, and anti-viral, backed by its high content of phytochemical compounds such vitexin, isovitexin, stigmasterol and lupeol has increased the demand for C. nutans in the market. Extensive work had been carried out on its content and pharmacological activity using fresh samples but limited studies for in vitro cultures of C. nutans . No genome size estimation has been done for C. nutans . Objective of this study was to analyse nuclear DNA content of C. nutans using flow cytometry. Preparation of different nuclei isolation buffer and stoichiometric DNA staining using propidium iodide was carried out. The genome size of C. nutans was estimated using Glycine max cv. Polanka as internal standard and its genome size was compared with in vitro plantlets of C. nutans. Flow cytometry analysis revealed that nuclear 2C DNA of C. nutans content is estimated at 1.75 ± 0.006 pg. Coefficient of variation in flow cytometric analysis was within the limit of 5% implying that the results were reliable with the Tris.MgCl 2 being the best nuclei isolation buffer. No significant difference was observed from field grown and in vitro C. nutans . This finding will assist further in genome size evolution analysis of Clinacanthus spp. and to determine polyploids for increased active compounds and biomass. replicate being performed on different days. In all the experiments, the fluorescence of at least 5000 nuclei to 10000 nuclei was measured. Conversion from picograms (pg) to base pair numbers was done as follows: 1 pg DNA is equivalent to 0.978 × 10 9 bp (Dolezel et al., 2007). The results were analysed using one way analysis of variance (ANOVA) using SPSS version 25. For significant effect, Tukey’s pairwise comparison was carried out with p value ≤ 0.05..","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48360274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats 埃塞俄比亚绵草氢甲醇下胚轴提取物对雄性Wistar大鼠精子及性腺指标的影响

Journal of Medicinal Plants Research Pub Date : 2021-11-30 DOI: 10.5897/jmpr2021.7172

A. Mansur, B. Adamu, H. Abdullahi

{"title":"Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats","authors":"A. Mansur, B. Adamu, H. Abdullahi","doi":"10.5897/jmpr2021.7172","DOIUrl":"https://doi.org/10.5897/jmpr2021.7172","url":null,"abstract":"Infertility resulting from sperm dysfunction is a serious health problem leading to psychological, economic, and medical implications worldwide. Borassus aethiopum is a plant that has been used as an aphrodisiac. This study evaluated the effect of hydromethanol hypocotyls extracts of B. aethiopum on the sperm and gonadal indices of male Wistar rats. The extract was prepared and administered orally at doses of (250, 500 and 1000 mg/kg) to 40 male Wistar rats, divided into four groups; three experimental groups and one control group (distilled water). Sperm parameters (count, motility, viability and morphology) and gonadal indices were determined. Testicular tissues were examined histologically for evidence of morphological changes. The extract increased significantly sperm count in a dosedependent manner across all treatment groups (p<0.05). Sperm viability was significantly increased in the treatment group after 7 days but was unaffected after 28 days of treatment. The histological examination of the testicular tissue showed evidence of increased spermatogenesis. Photomicrograph of the testes showed spermatogonia at different stages of maturation. Some areas of focal necrosis and evidence of spermatogenic arrest in the segment biopsied at the highest dose (1000 mg/kg) after 28 days of extract administration were observed. The results of this study suggest that the extract increases sperm count, motility and spermatogenesis at the doses tested and is likely to be beneficial in the management of male infertility.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43208199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Preliminary screening of the antimicrobial activity of nine medicinal plant species from Burkina Faso 布基纳法索9种药用植物抗菌活性的初步筛选

Journal of Medicinal Plants Research Pub Date : 2021-11-30 DOI: 10.5897/jmpr2021.7106

Youl Ollo, Yougbare Sibidou, L. Palpouguini, Y. Boubacar, M. Christian, T. Halidou, H. Adama, Traore Maminata

{"title":"Preliminary screening of the antimicrobial activity of nine medicinal plant species from Burkina Faso","authors":"Youl Ollo, Yougbare Sibidou, L. Palpouguini, Y. Boubacar, M. Christian, T. Halidou, H. Adama, Traore Maminata","doi":"10.5897/jmpr2021.7106","DOIUrl":"https://doi.org/10.5897/jmpr2021.7106","url":null,"abstract":"Infectious diseases, including skin infections, have always been treated by plants and other natural products since ancient times. This study investigated the antimicrobial activity of nine medicinal plant species from Gonsé Forest and Bangreweogo Park, Burkina Faso on seven microbial strains involved in skin infections. Sixty-eight organic and aqueous extracts from leaves, stem and root barks of the nine plants were tested on five bacterial and two fungal American Type Culture Collection (ATCC) strains using the disk diffusion and microdilution methods. Twenty-eight extracts (41.17%) from eight of the plants differently inhibited bacteria and fungi, the exception being Wissadula amplissima specie. Gram-positive Cocci (GPC) were the most sensitive to the extracts. Eleven extracts had a Minimum Inhibitory Concentration (MIC) lower than 1 mg/ml (MIC < 1 mg/ml). The extracts of Opilia celtidifolia gave the largest zones of inhibition ranging from 21.67 to 24.33 mm at 100 to 300 mg/ml on GPC and Candida albicans. Its MIC varied from 0.03 to 0.06 mg/ml on Streptococcus pyogenes, and from 0.07 to 0.24 mg/ml on Streptococcus agalactiae. Ethanolic extracts (80 and 96%) of Lawsonia inermis had MIC ranging from 0.29 to 9.37 mg/ml on the sensitive strains. The variable inhibitory activity displayed by the plants confirmed in part their traditional use in the treatment of some bacterial and fungal skin infections.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48314134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Protective effect of commercial extracts of oregano (Lippia graveolens) against cardiac ischemia-reperfusion damage 牛至(Lippia graveolens)商业提取物对心脏缺血再灌注损伤的保护作用

Journal of Medicinal Plants Research Pub Date : 2021-10-31 DOI: 10.5897/JMPR2021.7110

Gabriela Pérez Flores, Jose David Torres Tirado, Ramiro Martínez Acosta, Jorge Alejandro Chavez Aguirre, M. Pescador, M. C. Flores, Ashley Stephanie Herrera Godina, E. Guzmán

{"title":"Protective effect of commercial extracts of oregano (Lippia graveolens) against cardiac ischemia-reperfusion damage","authors":"Gabriela Pérez Flores, Jose David Torres Tirado, Ramiro Martínez Acosta, Jorge Alejandro Chavez Aguirre, M. Pescador, M. C. Flores, Ashley Stephanie Herrera Godina, E. Guzmán","doi":"10.5897/JMPR2021.7110","DOIUrl":"https://doi.org/10.5897/JMPR2021.7110","url":null,"abstract":"Cardiac ischemia includes severe damage to heart muscle tissue due to decreased or cessation of blood flow, which involves failure to supply nutrients and oxygenation to heart cells. Causes can include blockages due to fat and cholesterol deposits. These damages include cell apoptosis, calcium and sodium concentration imbalance, loss of contraction force, and formation of reactive oxygen species. In the present work, oregano extracts administered to Wistar rats were tested. After 15 days of treatment, the hearts were extracted and the pharmacological response was evaluated in Langendorff isolated perfused heart assay. Left ventricular contractility and perfusion pressure were evaluated before and after inducing an ischemia-reperfusion event by administering three different drugs to stimulate said response. The results, expressed as a percentage of loss of cardiac functionality, suggest a protective effect against cardiac damage in those hearts treated with the extracts after each event. \u0000 \u0000 Key words: Wistar rats, cardiac ischemia, Langendorff, oregano extracts.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"5 1","pages":"461-465"},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46147613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Studies of the anti-hyperglycemic and antioxidant activities of the extract of aerial yam (Dioscorea bulbifera) 地山薯蓣提取物抗高血糖和抗氧化活性的研究

Journal of Medicinal Plants Research Pub Date : 2021-10-31 DOI: 10.5897/JMPR2021.7167

Kelechi Nkechinyere Akinyele, B. Emma-Okon, Adeniyi Oluwadare Fajobi, A. Morakinyo, O. Oyedapo

{"title":"Studies of the anti-hyperglycemic and antioxidant activities of the extract of aerial yam (Dioscorea bulbifera)","authors":"Kelechi Nkechinyere Akinyele, B. Emma-Okon, Adeniyi Oluwadare Fajobi, A. Morakinyo, O. Oyedapo","doi":"10.5897/JMPR2021.7167","DOIUrl":"https://doi.org/10.5897/JMPR2021.7167","url":null,"abstract":"This study investigated the anti-hyperglycemic and antioxidant activities of methanol extract of Dioscorea bulbifera with a view to studying the possibility of utilizing the yam in the management of hyperglycemia. Methanol extracts of the peels (MEPL), fresh (MEFL), and the whole tuber (MEWT) were prepared, phytochemically screened and assayed for α-amylase. Hyperglycemia was induced in rats using intraperitoneal injections of streptozotocin (40 mg/kg bwt) for five days, followed by administration of various doses of extract. Fasting blood sugar, alpha amylase, total protein, lipid profiles, creatinine, albumin, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in plasma of test rats. The extracts were found to contain alkaloids, cardiac glycosides, carbohydrate, flavonoids, protein, saponins, tannins, triterpenoids and vitamin C and E. Preliminary assessment revealed that the whole tuber (MEWT) contained the highest levels of these phytochemicals and exhibited highest α-amylase inhibitory potential (47.54%, IC50 169.83 ± 18.64 μg/ml). Also, the extract possessed potent and concentration-dependent radical scavenging activities, comparable to that of the standard (Vitamin C). The extract also inhibited alpha amylase activity and caused significant improvement in elevated lipid profile and creatinine, comparable with that brought about by the standard drug Metformin. Histological examination of pancreatic section showed improved arrangement of islets of Langerhans in exocrine tissues of hyperglycemic groups treated with the extract when compared with hyperglycemic control. These results suggest that methanol extract of whole tubers possesses potent significant anti-hyperglycemic activity and that whole yam (without peeling) is appropriate for use in the management of hyperglycemia disorders. \u0000 \u0000 Key words: Dioscorea bulbifera, methanol extract, Streptozotozin, hyperglycemia, diabetes mellitus, antioxidants, lipid profile.","PeriodicalId":16387,"journal":{"name":"Journal of Medicinal Plants Research","volume":"5 1","pages":"503-514"},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46349691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0