Adelia S Maharani, Feda Anisah Makkiyah, Aulia Chairani, Nurfitri Bustamani
{"title":"A Study of Correlation Lumbar Lordosis, Stress, Central Adiposity with Low Back Pain in Undergraduate Medical Students.","authors":"Adelia S Maharani, Feda Anisah Makkiyah, Aulia Chairani, Nurfitri Bustamani","doi":"10.3340/jkns.2024.0169","DOIUrl":"10.3340/jkns.2024.0169","url":null,"abstract":"<p><strong>Objective: </strong>Low back pain (LBP) is a multifactorial musculoskeletal condition that reduces productivity at work and causes disability. Due to their lengthy lectures and heavy workload, medical students are more prone to experience LBP. This study aims to investigate the relationship between central adiposity, stress, lumbar lordosis and LBP.</p><p><strong>Methods: </strong>This study uses a cross-sectional analytical observational design. A total of 73 medical students served as the study's sample. Respondents self-completed the K-10 psychological assessment and the Nordic musculoskeletal questionnaire. Physical examination was then carried out to identify central adiposity and lumbar lordosis. Respondents having a history of malignancy, deformity, or spinal injury are excluded.</p><p><strong>Results: </strong>In the prevalence of LBP, 53.21% of respondents reported not experiencing LBP symptoms, while the remaining 46.79% experienced pain. Central adiposity had no significant association with LBP (p=0.872). Although moderate stress was common among those with LBP, stress did not show a clear association in the chi-square test. Logistic regression showed that lumbar lordosis had the strongest impact on the presence of LBP, with an odds ratio of 10.524 (p=0.001), and stress also contributed to LBP complaints (p=0.044).</p><p><strong>Conclusion: </strong>This study shows LBP is correlated with lumbar lordosis and stress; however, central adiposity is not correlated with LBP.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"578-584"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Khadem Ansari, Ebru Erzurumluoglu Gokalp, Emre Ozkara, Ozlem Aykac, Oguz Cilingir, Ertugrul Colak, Atilla Ozcan Ozdemir, Sevilhan Artan
{"title":"The Role of miRNA Expression Profiles in Different Biofluids in Aneurysm Rupture.","authors":"Sara Khadem Ansari, Ebru Erzurumluoglu Gokalp, Emre Ozkara, Ozlem Aykac, Oguz Cilingir, Ertugrul Colak, Atilla Ozcan Ozdemir, Sevilhan Artan","doi":"10.3340/jkns.2024.0171","DOIUrl":"10.3340/jkns.2024.0171","url":null,"abstract":"<p><strong>Objective: </strong>Intracranial aneurysm (IA) is a cerebrovascular disease in which the cerebral arteries become pathologically weakened. The molecular mechanisms behind the pathogenesis of IAs are poorly understood. MicroRNAs (miRNAs) are highly stable in body fluids and the expression signatures of specific circulating miRNAs may be associated with high rupture risk, severity, and clinical outcome of subarachnoid hemorrhage (SAH).</p><p><strong>Methods: </strong>The presented study aimed to detect miRNA-based biomarkers and evaluating the usability of blood for a non-invasive approach. Blood samples from 24 patients with unruptured IA (group 1), blood and cerebrospinal fluid (CSF) samples collected on day 5 after aneurysmal SAH (aSAH) from 24 patients with ruptured IA (group 2), and both the blood and CSF samples from 24 individuals without any positive IA history (control group) were subjected to quantitative real time polymerase chain reaction for evaluating the expression profiles of eight miRNAs.</p><p><strong>Results: </strong>miR-29a, miR-200a-3p, miR-451a, miR-1297, and miR-502-5p in blood and miR-29a, miR-200a-3p, miR-451a, miR-126, miR- 146a-5p, and miR-27b-3p in CSF were found to be differentially expressed in ruptured patients compared to controls. In both biofluids of ruptured cases, the differences in the expression profiles of miR-29a, miR-200a-3p, and miR-451a compared to controls were striking. The upregulation of miR-126, miR-200a-3p, miR-451a, and miR-502-5p in the ruptured group compared to unruptured patients suggesting that these miRNAs may be informative in predicting the risk of an aneurysmal rupture.</p><p><strong>Conclusion: </strong>miR-29a, miR-200a-3p, and miR-451 were significantly altered in patients with aSAH compared to controls in both biofluids. These findings suggest that these miRNAs could be candidate non-invasive biomarkers for aSAH.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"528-540"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aneurysm at the Trunk of the Medial-Type Persistent Trigeminal Artery Associated with Facial Pain : A Rare Case Report.","authors":"Na Il Shin, Hyung-Jin Lee","doi":"10.3340/jkns.2024.0107","DOIUrl":"10.3340/jkns.2024.0107","url":null,"abstract":"<p><p>Persistent trigeminal artery (PTA) is the most common residual manifestation of persistent carotid-vertebrobasilar anastomosis, with the medial-type (intrasellar or sphenoidal) PTA being exceptionally rare. Aneurysms originating from the PTA trunk are not common. We present a unique case of an aneurysm located at the trunk of the medial-type PTA in a patient presenting with trigeminal neuralgia who successfully managed by endovascular procedure. Furthermore, we discuss the anatomical features of this aneurysm and relevant reports, and examine the possible pathomechanism of the associated pain.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"622-627"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustaining Progress of the Journal of Korean Neurosurgical Society Amidst the Crisis in Korean Healthcare System.","authors":"Hee-Jin Yang","doi":"10.3340/jkns.2025.0169","DOIUrl":"10.3340/jkns.2025.0169","url":null,"abstract":"<p><p>The 2024 Journal Citation Reports (JCR) reveal that the impact factor (IF) for the Journal of Korean Neurosurgical Society (JKNS) has risen to 1.7, an increase from 1.4 in 2023. Meanwhile, Republic of Korea has been in turmoil in healthcare system since February 2024, provoked by government's sudden and drastic policy to increase medical school admissions. This situation has profoundly impacted medical research activities, in addition to clinical practice. There is concern about whether the Korean medical community can sustain and build upon its academic achievements once this situation is resolved. Maintaining the growth of a medical journal is becoming increasingly challenging. The JKNS must continue its previous efforts to sustain its current progress. To enhance its IF, JKNS should focus on recruiting high-quality review articles and becoming a preferred journal for authors by offering a rapid review process. Collaboration with subspecialty journals is also crucial to ensure that both JKNS and those journals can grow together.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":"68 5","pages":"497-500"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Value of Texture Analysis in Postoperative Recurrence of Chronic Subdural Hematoma.","authors":"Yu Yan, Jianchao Wang, Jincai Fang, Yunnong Song","doi":"10.3340/jkns.2024.0125","DOIUrl":"10.3340/jkns.2024.0125","url":null,"abstract":"<p><strong>Objective: </strong>Texture analysis is widely used in all walks of life, and also in medicine. This paper aims to discuss the value of texture analysis in postoperative recurrence of chronic subdural hematoma (CSDH).</p><p><strong>Methods: </strong>A total of 173 patients with CSDH who were hospitalized in our hospital from January 2018 to August 2023 were selected . All the patients underwent magnetic resonance imaging (MRI) examinations before surgery. According to whether patients with CSDH have relapsed after surgery, the patients are divided into recurrence group and non-recurrence group. FireVoxel software (https://firevoxel.org) was used to manually delineate the region of interest on the largest level of the hematoma cavity during MRI plain scans and measure the texture parameters. The texture parameters with statistical difference were analyzed by receiver operating characteristic curve.</p><p><strong>Results: </strong>Heterogeneity and entropy texture parameters in the recurrence group were statistically different from those in the nonrecurrence group (p<0.05). When the cut-off point of the heterogeneity parameter was 0.284, the sensitivity, specificity, and accuracy of judging whether CSDH relapsed were 83.3%, 80.4%, and 80.7%, respectively.</p><p><strong>Conclusion: </strong>Texture analysis of CSDH can provide a new method to judge the recurrence of patients with CSDH.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"592-599"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huseyin Dogu, Ali Osman Mucuoglu, Abdulkerim Gokoglu, Roya Gasimli, Emre Tepeli, Hidayet Akdemir
{"title":"Familial Cerebral Cavernous Malformations : A Clinical Series and Literature Review.","authors":"Huseyin Dogu, Ali Osman Mucuoglu, Abdulkerim Gokoglu, Roya Gasimli, Emre Tepeli, Hidayet Akdemir","doi":"10.3340/jkns.2025.0074","DOIUrl":"https://doi.org/10.3340/jkns.2025.0074","url":null,"abstract":"<p><strong>Objective: </strong>Familial cerebral cavernous malformation (FCCM) is a genetically inherited condition involving the collection of abnormal slow-flow venous capillaries with no cerebral parenchyma in between. In this case series, we review the clinical, radiological, pathological, and genetic findings of seven blood relatives diagnosed with FCCM and discuss their treatment in light of the different presentations.</p><p><strong>Methods: </strong>The patients with FCCMs were assessed in our neurosurgery clinic between April 2016 and October 2024. All patients underwent detailed clinical evaluation, radiological imaging, histopathological examination, and genetic testing. Functional outcomes were evaluated using the Karnofsky performance scale (KPS).</p><p><strong>Results: </strong>Five of the seven patients were symptomatic, while the remaining two were asymptomatic carriers. On radiological examination, hemorrhagic type I lesions were detected in symptomatic cases, whereas the asymptomatic carriers had non-hemorrhagic type 4 lesions. Genetic testing revealed a heterozygous pathogenic mutation in the CCM1 gene in one of the symptomatic patients. The three symptomatic cases underwent surgery for complete resection of the lesions; no additional neurological deficit or residual lesion was detected postoperatively (postoperative KPS score, 100). Histopathological examination revealed benign cavernous angioma in all cases. Over the postoperative follow-up, no seizures were detected in patients who underwent surgery due to refractory epilepsy.</p><p><strong>Conclusion: </strong>Advances in molecular genetic testing have allowed for prompt diagnosis and timely management of patients with FCCMs. Surgical treatment is an effective option in symptomatic cases with progressive neurological deficits and refractory epilepsy. Regular neurological monitoring and radiological assessment are recommended in symptomatic cases and asymptomatic carriers.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bekir Tunç, Oğuzhan Uzlu, Egemen Ünal, Ali Yılmaz, Ömer Faruk Şahin, Mağruf İlkay Yapakcı, Emin Çağıl
{"title":"Cervical Disc Surgery : A Pathway to Better Sleep and Enhanced Quality of Life - A Pre-Post Study Perspective.","authors":"Bekir Tunç, Oğuzhan Uzlu, Egemen Ünal, Ali Yılmaz, Ömer Faruk Şahin, Mağruf İlkay Yapakcı, Emin Çağıl","doi":"10.3340/jkns.2025.0016","DOIUrl":"https://doi.org/10.3340/jkns.2025.0016","url":null,"abstract":"<p><strong>Objective: </strong>Cervical disc herniation (CDH) is one of the most common pathologies that cause pain and functional loss in cervical spine disorders. The primary reasons for cervical disc patients' presentations are brachialgia, radiculopathy, and myelopathy. Pain leads to a decrease in sleep quality, and the reduction in sleep quality, in turn, negatively affects pain, resulting in a decline in quality of life. In the literature, there are limited studies evaluating pain, sleep quality, quality of life, and daily living activities in patients undergoing CDH surgery. Moreover, these studies do not adequately assess all these criteria together. Our study represents the most homogeneous (disconly) and comprehensive study in the current literature. We believe it will provide clear insights into the effects of CDH surgery and serve as a guide for preoperative patient selection and management.</p><p><strong>Methods: </strong>This research is a prospective study. Between July 2024 and December 2024, a total of 43 patients underwent surgery for CDH. The patients included in the study were evaluated preoperatively and on the 45th postoperative day using Visual analog scale (VAS), Pittsburgh sleep quality index (PSQI), European quality of life 5 dimensions 3 level version (EQ-5D-3L), Neck disability index (NDI), and Copenhagen neck functional disability scale (CNFDS) scales.</p><p><strong>Results: </strong>Of the 43 patients included in the study, 28 (65.1%) were female, with a mean age of 43.16±9.82 years. Regarding the levels affected, 25 patients (58.1%) had involvement at the C5-6 level, while 18 patients (41.9%) were at the C6-7 level. Significant improvements were observed in all parameters during the preoperative and postoperative evaluation of VAS, PSQI, EQ-5D-3L, NDI, and CNFDS scales (p<0.001 for each).</p><p><strong>Conclusion: </strong>In cervical disc patients with ineffective conservative treatment, radicular pain, muscle weakness, and extruded discs, as well as high preoperative scale scores, immediate surgical intervention will result in a reduction in pain and improvements in sleep, quality of life, and daily living activities.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae Sang Oh, Dongwook Seo, Jinwoo Jeong, Kyoung-Chul Cha, Yong Soo Cho, Su Jin Kim, Jongkyu Park, Won-Sang Cho, Se Won Oh, Jang Hun Kim, Hyeong Jin Lee, Hong Suk Ahn, Yuna Jo, Jung-Jae Kim, Kyoung Min Jang, Gi-Yong Yun, Jong Min Lee, Hoon Kim, Young Woo Kim, Tae Gon Kim, Sung-Kon Ha, Sukh Que Park, Soon Chan Kwon
{"title":"Clinical Practice Guideline for the Prehospital Stage in Acute Stroke : I. Use of Emergency Medical Services Assessment Tools.","authors":"Jae Sang Oh, Dongwook Seo, Jinwoo Jeong, Kyoung-Chul Cha, Yong Soo Cho, Su Jin Kim, Jongkyu Park, Won-Sang Cho, Se Won Oh, Jang Hun Kim, Hyeong Jin Lee, Hong Suk Ahn, Yuna Jo, Jung-Jae Kim, Kyoung Min Jang, Gi-Yong Yun, Jong Min Lee, Hoon Kim, Young Woo Kim, Tae Gon Kim, Sung-Kon Ha, Sukh Que Park, Soon Chan Kwon","doi":"10.3340/jkns.2025.0106","DOIUrl":"https://doi.org/10.3340/jkns.2025.0106","url":null,"abstract":"<p><p>Accurate and early identification of stroke and large vessel occlusion (LVO) in emergency settings is essential for improving patient outcomes and ensuring the efficient allocation of medical resources. This clinical practice guideline systematically reviews domestic and international literature and conducts meta-analyses to evaluate the utility and diagnostic accuracy of stroke assessment tools used in prehospital emergency medical services (EMS). We developed a guideline based on evidence from systematic reviews and meta-analyses via a de novo process. A systematic literature review was conducted to evaluate the usefulness of diagnostic EMS assessment tools for diagnosing stroke and LVO. Overall, 70 non-randomized control studies were selected for this study. A meta-analysis was conducted with a subgroup analysis to distinguish between patients with stroke and those with LVO. EMS tools demonstrated high sensitivity but low specificity for diagnosing stroke. In the prehospital setting, using validated EMS stroke assessment tools is recommended for the early identification of stroke and LVO. Upon hospital arrival, stroke specialists should conduct further evaluation and triage to confirm the diagnosis and guide appropriate management. Delays in diagnosing LVO are frequently unacceptable. While experts advocate for the use of EMS assessment tools to facilitate early identification of LVO, these tools alone lack adequate sensitivity. Therefore, further diagnostic evaluations and consultation with stroke specialists upon hospital arrival are recommended.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qi Tian, Sun Yu, Shuhai Long, Chengcheng Shi, Ji Ma, Zhen Li, Xuhua Duan, Yuncai Ran, Tengfei Li
{"title":"High-Resolution C-arm Computed Tomography for Evaluation of Stent Expansion and Apposition after Intracranial Stent Implantation.","authors":"Qi Tian, Sun Yu, Shuhai Long, Chengcheng Shi, Ji Ma, Zhen Li, Xuhua Duan, Yuncai Ran, Tengfei Li","doi":"10.3340/jkns.2024.0223","DOIUrl":"https://doi.org/10.3340/jkns.2024.0223","url":null,"abstract":"<p><strong>Objective: </strong>C-arm computed tomography (CT) has always played an important role in neurointerventional surgery, in this study, we aimed to investigate the value of high-resolution C-arm CT in evaluating stent expansion and apposition in carotid arteries of Guangxi Bama piglets.</p><p><strong>Methods: </strong>Twenty-four stents were implanted in the carotid arteries of 24 Guangxi Bama piglets. High-resolution C-arm CT was performed to evaluate stent expansion and the quality of processed images, followed by three-dimensional digital subtraction angiography (3D-DSA). The DSA and high-resolution C-arm CT images were transmitted to a postprocessing workstation for image reconstruction (dual-volume reconstruction method). High-resolution C-arm CT reconstructed images after diluted contrast agent injection (diluted contrast method) were also acquired. In addition to assessing radiation exposure, the accuracy of stent apposition assessment by the two methods was compared, using intravascular ultrasound as the reference standard. Adverse events during and within 24 hours after the procedure were recorded.</p><p><strong>Results: </strong>One stent was incompletely expanded, while the remaining 23 stents were fully expanded without disruption. The image quality of high-resolution CT was grade I in most cases (n=22/24). Both methods clearly demonstrated stent apposition with a consistency of 100%. However, the dual-volume reconstruction method was associated with significantly higher radiation exposure (p<0.001). Mild-tomoderate vasospasm occurred in four piglets when the diluted contrast method was used. Overall, no serious complications occurred in this study.</p><p><strong>Conclusion: </strong>High-resolution C-arm CT enables clear microstructure visualization and can be used in combination with different postprocessing techniques to accurately assess the apposition of intracranial stents.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ki-Su Park, Minjoon Kim, Taegon Kim, Seongyun Kim, Seong-Hyun Park, Eunhee Park, Kyunghun Kang
{"title":"Clinical Outcomes of Lumboperitoneal Shunt Surgery for Normal Pressure Hydrocephalus : A 5-Year Single-Center Retrospective Study of Patients with at Least 1 Year of Follow-Up.","authors":"Ki-Su Park, Minjoon Kim, Taegon Kim, Seongyun Kim, Seong-Hyun Park, Eunhee Park, Kyunghun Kang","doi":"10.3340/jkns.2025.0094","DOIUrl":"https://doi.org/10.3340/jkns.2025.0094","url":null,"abstract":"<p><strong>Objective: </strong>Lumboperitoneal shunt (LPS) surgery is a widely used treatment for normal pressure hydrocephalus, especially in East Asia. Although LPS surgery has been widely studied internationally, large-scale data from the Republic of Korea are limited. This study aimed to evaluate clinical outcomes and complications of LPS surgery in NPH patients, with particular focus on anesthesia type and valve pressure management strategies.</p><p><strong>Methods: </strong>A retrospective review was conducted of 244 patients with normal pressure hydrocephalus who underwent LPS surgery between February 2020 and February 2025. Valve pressures were initially set at the highest level and gradually adjusted downward based on clinical response. Functional outcomes-including the modified Rankin Scale (mRS), Timed Up and Go (TUG), 10-meter gait test, and Mini-Mental State Examination (MMSE)-were assessed at 1 year and followed for up to 4 years. Complications were categorized by type and whether surgical intervention was required.</p><p><strong>Results: </strong>Among 244 patients, 119 completed at least 1 year of follow-up. At 1 year, 53.8% of patients showed mRS improvement, and 66.4% demonstrated gait improvements (TUG and 10-meter walk). Stable or improved function was observed in 93.3% of patients. MMSE scores did not show significant change. The overall complication rate was 16.8%, with 11.1% requiring surgical revision, primarily for chronic subdural hematoma and catheter-related issues. No surgery-related mortality occurred, but three patients (1.2%) died from falls despite improved gait, underscoring the need for fall prevention. The adoption of an initial high-pressure setting reduced overdrainage-related complications, contributing to a decreased annual revision rate of 5.6%.</p><p><strong>Conclusion: </strong>A retrospective study showed that LPS surgery with local anesthesia is effective for NPH patients, demonstrating favorable functional outcomes and acceptable complications. Using higher initial valve pressures significantly decreased the need for revision surgeries and complications related to overdrainage.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}