Journal of Korean Neurosurgical Society最新文献

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Minimally Invasive Biportal Endoscopic Spinal Cord Stimulation : Technical Report and Case Series. 微创双门静脉内窥镜脊髓刺激:技术报告和病例系列。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-10-02 DOI: 10.3340/jkns.2025.0051
Young San Ko, Dae-Chul Cho
{"title":"Minimally Invasive Biportal Endoscopic Spinal Cord Stimulation : Technical Report and Case Series.","authors":"Young San Ko, Dae-Chul Cho","doi":"10.3340/jkns.2025.0051","DOIUrl":"https://doi.org/10.3340/jkns.2025.0051","url":null,"abstract":"<p><strong>Objective: </strong>The insertion of a surgical paddle lead for spinal cord stimulation (SCS) is a cornerstone therapy for chronic refractory pain, with lower impedance and reduced battery usage than a percutaneous lead. However, the greater invasiveness of this procedure can cause complications.</p><p><strong>Methods: </strong>This study introduces a novel SCS technique using the unilateral biportal endoscopy (UBE) approach, illustrated through intraoperative images and endoscopic videos. We retrospectively reviewed 14 patients who underwent SCS using the UBE technique. Clinical, surgical, and radiological data were collected from electronic medical records and surgical videos.</p><p><strong>Results: </strong>A total of 14 patients (five females, nine males) were included in the study. The mean endoscopic operating time was 76.3±22.3 minutes. After the trial period, 13 patients (92.8%, 13/14) improved and underwent permanent implantation. The complication rate was 21.4%, with two cases of thoracic radiculopathy and one case of asymmetrical lead positioning. No lead migration was observed in these 13 patients.</p><p><strong>Conclusion: </strong>This study demonstrated the safety and efficacy of UBE-SCS as a minimally invasive alternative to conventional techniques, with high success rates and acceptable complications. However, further large-scale, long-term comparative studies are needed.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of Angle Loss after L4/5 Oblique Lumbar Interbody Fusion : Development of a Risk Stratification Model. 腰椎4/5斜椎体间融合术后角度损失的预测:风险分层模型的建立。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-30 DOI: 10.3340/jkns.2025.0109
Se-Woon Kim, Su-Hun Lee, Jun-Seok Lee, Chi-Hyung Lee, Chang-Hyun Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee
{"title":"Prediction of Angle Loss after L4/5 Oblique Lumbar Interbody Fusion : Development of a Risk Stratification Model.","authors":"Se-Woon Kim, Su-Hun Lee, Jun-Seok Lee, Chi-Hyung Lee, Chang-Hyun Kim, Soon-Ki Sung, Dong-Wuk Son, Sang-Weon Lee","doi":"10.3340/jkns.2025.0109","DOIUrl":"https://doi.org/10.3340/jkns.2025.0109","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the influence of preoperative disc morphology and cage-related variables on disc angle change following single-level L4/5 oblique lumbar interbody fusion (OLIF), and to identify predictors of postoperative angle loss and angular subsidence.</p><p><strong>Methods: </strong>This retrospective study analyzed 80 patients who underwent L4/5 OLIF with posterior percutaneous screw fixation and 1-year radiographic follow-up. Radiographic parameters included preoperative disc angle (DAPRE), sacral slope (SS), and cage position along the anteroposterior axis (Cage_Y). Postoperative disc angle loss was defined as a decrease in disc angle immediately after surgery. Angular subsidence was defined as a decrease in disc angle at follow-up compared to the postoperative period multivariate logistic regression was used to identify independent predictors of these outcomes. Threshold values were determined by receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>DAPRE >6.0°, SS <32.0°, and posterior cage placement (Cage_Y <1.9 mm) were independently associated with immediate angle loss. Among them, DAPRE showed the strongest predictive power (odds ratio, 7.9). Additionally, a greater initial angular gain was associated with a higher risk of angular subsidence. Based on these three parameters, a risk score (0-3 points) was generated, which showed a stepwise increase in the incidence of angle loss (0% to 81.3%) and subsidence over follow-up.</p><p><strong>Conclusion: </strong>DAPRE, SS, and Cage_Y are key predictors of disc angle outcomes after OLIF. This model provides a simple, clinically applicable tool to predict alignment maintenance and optimize surgical planning in degenerative lumbar conditions.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hwan Yung Chung : Founder of Korean Spinal Neurosurgery. 焕容钟:韩国脊柱神经外科的创始人。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-29 DOI: 10.3340/jkns.2025.0062
Chun Kee Chung, Byeong-Jin Ha, Koang Hum Bak, Jae Min Kim, Choong Hyun Kim, Yong Ko, Suck Jun Oh
{"title":"Hwan Yung Chung : Founder of Korean Spinal Neurosurgery.","authors":"Chun Kee Chung, Byeong-Jin Ha, Koang Hum Bak, Jae Min Kim, Choong Hyun Kim, Yong Ko, Suck Jun Oh","doi":"10.3340/jkns.2025.0062","DOIUrl":"https://doi.org/10.3340/jkns.2025.0062","url":null,"abstract":"<p><p>Professor Chung, an Emeritus Professor at Hanyang University School of Medicine, was a pioneering figure in Korean neurosurgery. After serving as an Army Surgeon during the Korean War, he specialized in neurosurgery, training under Professor Joo Geol Lee at Capital Medical College. Throughout his career, Professor Chung introduced numerous innovations in spinal surgery, including lumbar interbody fusion with metal support, anterior cervical foraminotomy, and the early adoption of microsurgery and motorized drills. In 1972, he became the first Chairman of the Department of Neurosurgery at Hanyang University Hospital, where he established a leading neurosurgical center. His contributions extended beyond clinical practice-he founded the Korean Spinal Neurosurgery Society in 1987 and served as President of Hanyang University Hospital from 1986 to 1987. Even after retirement, he remained active in the field, practicing and contributing to neurosurgery until his passing in 2016. He strongly emphasized continuous learning and international collaboration, fostering relationships with global spine surgery leaders and actively participating in international conferences. His dedication to minimally invasive techniques and surgical innovation profoundly impacted Korean neurosurgery, inspiring future generations and significantly advancing the field.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Biomarkers and Underlying Mechanisms of Mitochondrial and PCD Related Genes in Epilepsy by Combining Transcriptome and Single-Cell Sequencing. 结合转录组和单细胞测序研究癫痫线粒体和PCD相关基因的生物标志物和潜在机制。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-29 DOI: 10.3340/jkns.2024.0230
Wang Xiaoqiang, Wang Ren, Zhang Jianglong
{"title":"The Biomarkers and Underlying Mechanisms of Mitochondrial and PCD Related Genes in Epilepsy by Combining Transcriptome and Single-Cell Sequencing.","authors":"Wang Xiaoqiang, Wang Ren, Zhang Jianglong","doi":"10.3340/jkns.2024.0230","DOIUrl":"https://doi.org/10.3340/jkns.2024.0230","url":null,"abstract":"<p><strong>Objectives: </strong>Reactive oxygen species generated by mitochondria contribute to the induction of programmed cell death (PCD), but their involvement in epilepsy remains uncertain. The present study investigates the biomarkers and underlying mechanisms of mitochondria-related genes (MRGs) and PCD-related genes (PCDRGs) in epilepsy.</p><p><strong>Methods: </strong>The MRGs and PCDRGs were respectively intersected with differentially expressed genes (DEGs) in epilepsy and control samples within the GSE134697.Afterwards, Spearman correlation analysis was implemented to select candidate genes. Thereafter, candidate biomarkers were identified through intersection of eight algorithm results in cytoHubba plugin. The receiver operating characteristic (ROC) curve analysis and expression validation in GSE134697 and GSE168375 were implemented to select biomarkers. Moreover, functional analysis, drug prediction and molecular docking were carried out to explore the mechanism of biomarkers in epilepsy, as well as single cell RNA sequencing analysis. Finally, the expression of biomarkers in clinical sample was validated by RT-qPCR.</p><p><strong>Results: </strong>LTBR and IRF1 were down-regulated in epilepsy samples in both GSE134697 and GSE168375 datasets, Therefore, they were identified as biomarkers for epilepsy related to PCD and mitochondria. IRF1 formed a hydrogen bond interaction with the RECOMBINANT CYTOKINE,indicating RECOMBINANT CYTOKINE was an effective drug target, while LTBR was not a suitable drug target. The macrophage was observed to engage in more frequent and intensive interactions with other cells. RT-qPCR showed that both biomarkers also low expression in epilepsy clinical samples.</p><p><strong>Conclusion: </strong>LTBR, IRF1 were identified as biomarkers associated with mitochondria and PCD in epilepsy, providing novel perspectives on the management of this condition.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Higher Arterial Oxygen Levels Associated with Improved Survival in Neurocritically Ill Brain Tumor Patients. 高动脉血氧水平与神经危重型脑肿瘤患者生存率提高相关
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-24 DOI: 10.3340/jkns.2025.0042
Sung-Jin Lee, Yu Min Seong, Sook-Young Woo, Kwang-Hyuck Lee, Jeong-Am Ryu
{"title":"Higher Arterial Oxygen Levels Associated with Improved Survival in Neurocritically Ill Brain Tumor Patients.","authors":"Sung-Jin Lee, Yu Min Seong, Sook-Young Woo, Kwang-Hyuck Lee, Jeong-Am Ryu","doi":"10.3340/jkns.2025.0042","DOIUrl":"https://doi.org/10.3340/jkns.2025.0042","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the relationship between arterial partial pressure of oxygen (PaO2) levels in the first 24 hours of intensive care unit (ICU) admission and clinical outcomes in neurocritically ill brain tumor patients.</p><p><strong>Methods: </strong>In this single-center retrospective study of 2123 brain tumor patients, we analyzed PaO2 levels from arterial blood gas samples within 24 hours of ICU admission. The primary endpoint was 28-day mortality. Analysis utilized multivariable logistic regression and inverse probability of treatment weighting (IPTW).</p><p><strong>Results: </strong>PaO2 exceeding 91.5 mmHg was defined as hyperoxia. The non-hyperoxia group showed higher 28-day mortality than the hyperoxia group (15.5% vs. 6.0%, p<0.002), a trend that persisted after IPTW adjustment (10.7% vs. 6.6%, p=0.019). In IPTW-adjusted regression, non-hyperoxia remained significant (adjusted odds ratio [OR], 3.24; 95% confidence interval [CI], 1.82-5.77). Survival analysis demonstrated significantly higher survival rates in the hyperoxia group (p<0.001). Subgroup analysis revealed significant heterogeneity across tumor types (p for interaction <0.001), with protective effects observed in malignant brain tumors (adjusted OR, 3.5; 95% CI, 1.88- 6.51) and brain metastases (adjusted OR, 3.86; 95% CI, 2.31-6.44), but not in benign tumors (adjusted OR, 1.14; 95% CI, 0.22-5.87).</p><p><strong>Conclusion: </strong>Elevated PaO2 levels within the first 24 hours of ICU admission were associated with decreased mortality rates, suggesting oxygenation as a potential therapeutic target in brain tumor patients. The protective effects were most pronounced in patients with malignant brain tumors and brain metastases, supporting a tumor type-specific approach to oxygenation management.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote Spinal Subdural Hematoma Following Lumbar Biportal Endoscopic Surgery : Two Case Reports. 腰椎双门静脉内窥镜手术后远端脊髓硬膜下血肿:2例报告。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-19 DOI: 10.3340/jkns.2025.0167
Sang Youp Han, Jae-Won Jang, Yong Eun Cho, Choon-Keun Park
{"title":"Remote Spinal Subdural Hematoma Following Lumbar Biportal Endoscopic Surgery : Two Case Reports.","authors":"Sang Youp Han, Jae-Won Jang, Yong Eun Cho, Choon-Keun Park","doi":"10.3340/jkns.2025.0167","DOIUrl":"https://doi.org/10.3340/jkns.2025.0167","url":null,"abstract":"<p><p>Remote spinal subdural hematoma (SSH) following unilateral biportal endoscopic (UBE) spine surgery is rare, even without intraoperative dural injury. We report two such cases. A 76-year-old woman underwent anterior lumbar interbody fusion and UBE decompression for lumbar spinal stenosis. Intraoperatively, dense adhesions were noted, but no cerebrospinal fluid (CSF) leakage occurred. Postoperatively, she developed left leg monoplegia. MRI revealed a subdural hematoma at L2-3, remote from the surgical site. She recovered completely with steroid therapy and conservative management. An 88-year-old man underwent left-sided UBE laminotomy for central stenosis. The procedure was uneventful. Postoperative MRI revealed an incidental subdural hematoma from L2-4 without neurological deficits. He was observed conservatively. Both patients showed favorable outcomes without surgical evacuation. Remote SSH is a rare but important complication following UBE surgery. It should be considered when unexpected neurological deficits occur postoperatively, even in the absence of visible dural tears. Prompt diagnosis is essential for optimal management.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
miRNA Expression Profiles in Different Biofluids in Aneurysm Rupture. 动脉瘤破裂中不同生物体液中miRNA的表达谱
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-17 DOI: 10.3340/jkns.2025.0182
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"miRNA Expression Profiles in Different Biofluids in Aneurysm Rupture.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.3340/jkns.2025.0182","DOIUrl":"https://doi.org/10.3340/jkns.2025.0182","url":null,"abstract":"","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between Erythrocyte Sedimentation Rate/CRP Ratio and Procalcitonin Values in Postoperative Spondylodiscitis : Potential Biomarker Comparison. 术后脊柱炎患者红细胞沉降率/CRP比值与降钙素原值的相关性:潜在的生物标志物比较
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-12 DOI: 10.3340/jkns.2025.0067
Ömer Faruk Şahin, Oğuzhan Uzlu, Bekir Tunç, Ali Yılmaz, Mağruf İlkay Yapakcı, Ahmet Burak Gürpınar
{"title":"Correlation between Erythrocyte Sedimentation Rate/CRP Ratio and Procalcitonin Values in Postoperative Spondylodiscitis : Potential Biomarker Comparison.","authors":"Ömer Faruk Şahin, Oğuzhan Uzlu, Bekir Tunç, Ali Yılmaz, Mağruf İlkay Yapakcı, Ahmet Burak Gürpınar","doi":"10.3340/jkns.2025.0067","DOIUrl":"https://doi.org/10.3340/jkns.2025.0067","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative spondylodiscitis is a rare but serious complication of spinal surgery. The difficulty in establishing an early diagnosis necessitates the evaluation of novel biomarkers. This study aims to determine the diagnostic value of procalcitonin (PCT), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ESR/CRP, and ESR/PCT ratios in the diagnosis of postoperative spondylodiscitis and to compare the sensitivity and specificity of these parameters.</p><p><strong>Methods: </strong>This retrospective study was conducted by evaluating 55 patients who underwent two-level lumbar instrumentation (foraminotomy-medial facetectomy and microdiscectomy, autologous graft with fusion) between 2019 and 2023.. Laboratory values of 28 patients diagnosed with postoperative spondylodiscitis and 27 control patients with no signs of infection were analyzed. The cut-off values, sensitivity, specificity, positive and negative predictive values, and area under the curve (AUC) of CRP, ESR, PCT, ESR/CRP, and ESR/PCT ratios were calculated using receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>CRP, ESR, and PCT levels were significantly elevated in patients with spondylodiscitis (p < 0.05). The ESR/PCT ratio demonstrated 96% specificity and was considered a supportive marker for the diagnosis of spondylodiscitis. However, the ESR/CRP ratio did not show a significant difference between the two groups (p = 0.222). The cut-off value for CRP was determined as 43.7 mg/L, with a specificity of 100%. The cut-off value for ESR was 46 mm/hour, with a sensitivity of 92.9%. The cut-off value for PCT was found to be 0.034 ng/mL, with a sensitivity of 96.2%.</p><p><strong>Conclusion: </strong>CRP and ESR/PCT ratios were found to be effective in supporting the diagnosis of postoperative spondylodiscitis due to their high specificity. On the other hand, ESR and PCT demonstrated higher sensitivity, making them more successful in distinguishing non-infected individuals. However, no single biomarker was deemed sufficient on its own, emphasizing the necessity of clinical evaluation alongside laboratory findings. Prospective studies are needed in the future to enhance the diagnostic accuracy of these biomarkers.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of Sulcal Hyperintense Vessel (Vessel Wall MR Ivy Sign) in Adult Moyamoya Disease with High-Resolution Vessel Wall Imaging : A Pilot Study. 用高分辨率血管壁成像识别成人烟雾病的沟高信号血管(血管壁MR常青藤征):一项初步研究
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-01 Epub Date: 2025-01-10 DOI: 10.3340/jkns.2024.0096
Ju In Park, Jae Seong Hong, Jiwook Ryu, Kyung Mi Lee, Ho Geol Woo, Seok Keun Choi
{"title":"Identification of Sulcal Hyperintense Vessel (Vessel Wall MR Ivy Sign) in Adult Moyamoya Disease with High-Resolution Vessel Wall Imaging : A Pilot Study.","authors":"Ju In Park, Jae Seong Hong, Jiwook Ryu, Kyung Mi Lee, Ho Geol Woo, Seok Keun Choi","doi":"10.3340/jkns.2024.0096","DOIUrl":"10.3340/jkns.2024.0096","url":null,"abstract":"<p><strong>Objective: </strong>The leptomeningeal ivy sign is a distinctive finding of Moyamoya disease (MMD), characterized by a linear high signal intensity along the cortical sulci on contrast-enhanced T1 magnetic resonance imaging (MRI) and fluid-attenuated inversion-recovery (FLAIR) MRI. We recently identified a similar linear enhancement along the cortical sulci using gadolinium-enhanced vessel wall MRI (VWMR) in patients with MMD. The aim of this study was to introduce the concept of the \"VWMR ivy sign (VIS)\".</p><p><strong>Methods: </strong>Eighteen MMD patients underwent gadolinium-enhanced VWMR. We identified the VIS in gadolinium-enhanced VWMR, represented by a linear high intensity along the cortical sulci. The VIS was assessed by comparing pre and postcontrast T1 black blood sequences on VWMR and was investigated in the precentral, central, and postcentral sulci. \"VIS scores\" were calculated by the sum of VIS in the three sulci, ranged from 0 to 3. We compared the VIS scores according to different stroke presentations (non-stroke, ischemic stroke, and hemorrhagic stroke). The inter-modality agreement for identifying VIS and FLAIR/cortical sulci on contrast-enhanced T1 MRI (CEMR) ivy sign was determined using Cohen's kappa statistics.</p><p><strong>Results: </strong>The VIS scores were significantly different among the three groups (p=0.004). The VIS scores in both the ischemic and hemorrhagic groups were significantly higher than those in the non-stroke group (ischemic vs. non-stroke, p=0.009; hemorrhagic vs. non-stroke, p=0.004). After adjusting for age and sex using the non-stroke group as a reference group, the VIS scores were significantly higher in the ischemic and hemorrhagic groups (p=0.046; odds ratio [OR], 8.27; 95% confidence interval [CI], 1.03-66.19 and p=0.039; OR, 7.78; 95% CI, 1.11-54.48, respectively). The intermodality agreement between VIS and FLAIR ivy sign was substantial in the precentral region, perfect in the central region, and substantial in the postcentral region (precentral sulcus : κ=0.609; 95% CI, 0.213-1; central sulcus : κ=1; and postcentral sulcus : κ=0.769; 95% CI, 0.475-1). Inter-modality agreement between the VIS and CEMR ivy sign was substantial in the precentral, central, and postcentral sulci, respectively (precentral sulcus : κ=0.727; 95% CI, 0.384-1; central sulcus : κ=0.609; 95% CI, 0.384-1; and postcentral sulcus : κ=0.649, 95% CI, 0.310-0.998).</p><p><strong>Conclusion: </strong>This preliminary series introduces the concept of VIS, possibly indicating slow and retrograde flow of sulcal vessels via leptomeningeal collaterals. Future studies are needed to develop an optimal scoring system for VIS and establish its clinical correlation with stroke presentations in MMD patients.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"558-567"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of Ambulatory Functions Based on Somatosensory and Motor-Evoked Potentials in Patients with Intracerebral Hemorrhage and Intraventricular Hemorrhage Extension. 基于体感和运动诱发电位预测脑出血和脑室内出血扩展患者的运动功能。
IF 1.7 4区 医学
Journal of Korean Neurosurgical Society Pub Date : 2025-09-01 Epub Date: 2025-02-04 DOI: 10.3340/jkns.2024.0192
Min Cheol Chang, Seong Yeob Kwak, Soyoung Kwak
{"title":"Prediction of Ambulatory Functions Based on Somatosensory and Motor-Evoked Potentials in Patients with Intracerebral Hemorrhage and Intraventricular Hemorrhage Extension.","authors":"Min Cheol Chang, Seong Yeob Kwak, Soyoung Kwak","doi":"10.3340/jkns.2024.0192","DOIUrl":"10.3340/jkns.2024.0192","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the usefulness of somatosensory-evoked potentials (SEPs) and motor-evoked potentials (MEPs) in predicting motor outcomes in patients with intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) extension.</p><p><strong>Methods: </strong>We retrospectively evaluated 124 patients with ICH and IVH extensions. SEPs of posterior tibial nerve and MEPs of tibialis anterior muscles were evaluated.</p><p><strong>Results: </strong>About 30% of the patients could walk independently at 6 months from the onset. Patients who exhibited SEP in both bilateral posterior tibial nerves demonstrated better ambulatory function compared to those with SEP in only one unilateral posterior tibial nerve or no SEP in both sides of the posterior tibial nerves. Likewise, patients who displayed MEP in both bilateral tibialis anterior muscles exhibited better ambulatory capacity compared to those with MEP on only one side or no MEP on both sides. In addition, when the posterior tibial nerve SEP was present bilaterally, 54.9% of the patients could walk independently, and when the MEP from the tibialis anterior muscles was present bilaterally, 41.0% of the patients could walk without any assistance.</p><p><strong>Conclusion: </strong>SEP and MEP could be useful tools for predicting ambulatory function in patients with ICH accompanied by IVH.</p>","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"609-615"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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