Journal of Korean Neurosurgical Society最新文献_第10页

Update on the Vein of Galen Aneurysmal Malformation : Disease Concept and Genetics. Galen 静脉动脉瘤畸形的最新进展：疾病概念与遗传学。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 Epub Date: 2024-03-20 DOI: 10.3340/jkns.2024.0058

Hyun-Seung Kang

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A Review of the Current State and Future Directions for Management of Scalp and Facial Vascular Malformations. 头皮和面部血管畸形管理现状及未来方向综述。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 DOI: 10.3340/jkns.2024.0032

Emma Hartman, Daniel M Balkin, Alfred Pokmeng See

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Natural history and clinical manifestation of Pediatric Brain Arteriovenous Malformations. 小儿脑动静脉畸形的自然史和临床表现。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 DOI: 10.3340/jkns.2024.0037

Adikarige Haritha Dulanka Silva, Greg James

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Preface : Invited Issue Editor, Professor Edward R. Smith, and the Pediatric Vascular Malformations of the Central Nervous System. 前言：本期特邀编辑 Edward R. Smith 教授和儿科中枢神经系统血管畸形。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 Epub Date: 2024-03-05 DOI: 10.3340/jkns.2024.0048

Jun Bum Park, Seung-Ki Kim

引用次数: 0

Pediatric Central Nervous System Vascular Malformation : Pathological Review with Diagram. 小儿中枢神经系统血管畸形：病理回顾与图解》（Pediatric Central Nervous System Vascular Malformation : Pathological Review with Diagram.

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 Epub Date: 2024-03-13 DOI: 10.3340/jkns.2024.0006

Se Hoon Kim

引用次数: 0

Clinical Features and Treatment of Pediatric Cerebral Cavernous Malformations. 小儿脑腔畸形的临床特征和治疗。

IF 1.4 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 Epub Date: 2024-03-28 DOI: 10.3340/jkns.2024.0047

Ji Hoon Phi, Seung-Ki Kim

引用次数: 0

Choroid Plexus Hyperplasia : Report of Two Cases with Unique Radiologic Findings. 脉络丛增生：两例独特放射学表现的报告。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 Epub Date: 2023-10-18 DOI: 10.3340/jkns.2023.0126

Joo Whan Kim, Waka Hisamura, Seung-Ki Kim, Ji Hoon Phi

{"title":"Choroid Plexus Hyperplasia : Report of Two Cases with Unique Radiologic Findings.","authors":"Joo Whan Kim, Waka Hisamura, Seung-Ki Kim, Ji Hoon Phi","doi":"10.3340/jkns.2023.0126","DOIUrl":"10.3340/jkns.2023.0126","url":null,"abstract":"Choroid plexus hyperplasia (CPH), also known as diffuse villous hyperplasia of choroid plexus, is a rare condition characterized by excessive production of cerebrospinal fluid (CSF), resulting in hydrocephalus. Diagnosing CPH can be challenging due to the absence of clear imaging criteria for choroid plexus hypertrophy and the inability to assess CSF production non-invasively. As a result, many CPH patients are initially treated with a ventriculoperitoneal (VP) shunt, but subsequently require additional surgical intervention due to intractable ascites. In our study, we encountered two CPH patients who presented with significantly enlarged subarachnoid spaces, reduced parenchymal volume, and prominent choroid plexus. Initially, we treated these patients with a VP shunt, but eventually opted for endoscopic choroid plexus cauterization (CPC) to address the intractable ascites. Following the treatment with endoscopic CPC, we observed a gradual reduction in subarachnoid spaces and an increase in parenchymal volume. In cases where bilateral prominent choroid plexus, markedly enlarged subarachnoid spaces, and cortical atrophy are present, CPH should be suspected. In these cases, considering initial treatment with combined endoscopic CPC and shunt may help minimize the need for multiple surgical interventions.","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"376-381"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11079559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41236028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High Expression of KIFC1 in Glioma Correlates with Poor Prognosis. 胶质瘤中 KIFC1 的高表达与预后不良有关

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-05-01 DOI: 10.3340/jkns.2023.0155

Pengfei Xue, Juan Zheng, Rongrong Li, Lili Yan, Zhaohao Wang, Qingbin Jia, Lianqun Zhang, Xin Li

{"title":"High Expression of KIFC1 in Glioma Correlates with Poor Prognosis.","authors":"Pengfei Xue, Juan Zheng, Rongrong Li, Lili Yan, Zhaohao Wang, Qingbin Jia, Lianqun Zhang, Xin Li","doi":"10.3340/jkns.2023.0155","DOIUrl":"10.3340/jkns.2023.0155","url":null,"abstract":"Objective: Kinesin family member C1 (KIFC1), a non-essential kinesin-like motor protein, has been found to serve a crucial role in supernumerary centrosome clustering and the progression of several human cancer types. However, the role of KIFC1 in glioma has been rarely reported. Thus, the present study aimed to investigate the role of KIFC1 in glioma progression.Methods: Online bioinformatics analysis was performed to determine the association between KIFC1 expression and clinical outcomes in glioma. Immunohistochemical staining was conducted to analyze the expression levels of KIFC1 in glioma and normal brain tissues. Furthermore, KIFC1 expression was knocked in the glioma cell lines, U251 and U87MG, and the functional roles of KIFC1 in cell proliferation, invasion and migration were analyzed using cell multiplication, wound healing and Transwell invasion assays, respectively. The autophagic flux and expression levels matrix metalloproteinase-2 (MMP2) were also determined using imaging flow cytometry, western blotting and a gelation zymography assay.Results: The results revealed that KIFC1 expression levels were significantly upregulated in glioma tissues compared with normal brain tissues, and the expression levels were positively associated with tumor grade. Patients with glioma with low KIFC1 expression levels had a more favorable prognosis compared with patients with high KIFC1 expression levels. In vitro, KIFC1 knockdown not only inhibited the proliferation, migration and invasion of glioma cells, but also increased the autophagic flux and downregulated the expression levels of MMP2.Conclusion: Upregulation of KIFC1 expression may promote glioma progression and KIFC1 may serve as a potential prognostic biomarker and possible therapeutic target for glioma.","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":"67 3","pages":"364-375"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11079566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proper Indication of Decompressive Craniectomy for the Patients with Massive Brain Edema after Intra-arterial Thrombectomy. 动脉内血栓清除术后大面积脑水肿患者进行减压开颅手术的正确指征

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-03-01 Epub Date: 2024-01-04 DOI: 10.3340/jkns.2023.0130

Sang-Hyuk Im, Do-Sung Yoo, Hae-Kwan Park

{"title":"Proper Indication of Decompressive Craniectomy for the Patients with Massive Brain Edema after Intra-arterial Thrombectomy.","authors":"Sang-Hyuk Im, Do-Sung Yoo, Hae-Kwan Park","doi":"10.3340/jkns.2023.0130","DOIUrl":"10.3340/jkns.2023.0130","url":null,"abstract":"Objective: Numerous studies have indicated that early decompressive craniectomy (DC) for patients with major infarction can be life-saving and enhance neurological outcomes. However, most of these studies were conducted by neurologists before the advent of intra-arterial thrombectomy (IA-Tx). This study aims to determine whether neurological status significantly impacts the final clinical outcome of patients who underwent DC following IA-Tx in major infarction.Methods: This analysis included 67 patients with major anterior circulation major infarction who underwent DC after IA-Tx, with or without intravenous tissue plasminogen activator. We retrospectively reviewed the medical records, radiological findings, and compared the neurological outcomes based on the \"surgical time window\" and neurological status at the time of surgery.Results: For patients treated with DC following IA-Tx, a Glasgow coma scale (GCS) score of 7 was the lowest score correlated with a favorable outcome (p=0.013). Favorable outcomes were significantly associated with successful recanalization after IA-Tx (p=0.001) and perfusion/diffusion (P/D)-mismatch evident on magnetic resonance imaging performed immediately prior to IA-Tx (p=0.007). However, the surgical time window (within 36 hours, p=0.389; within 48 hours, p=0.283) did not correlate with neurological outcomes.Conclusion: To date, early DC surgery after major infarction is crucial for patient outcomes. However, this study suggests that the indication for DC following IA-Tx should include neurological status (GCS ≤7), as some patients treated with early DC without considering the neurological status may undergo unnecessary surgery. Recanalization of the occluded vessel and P/D-mismatch are important for long-term neurological outcomes.","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"227-236"},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10924906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139087221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea. 现代再灌注治疗对急性缺血性中风的现实影响：韩国一项基于全国人口的数据研究。

IF 1.6 4区医学

Journal of Korean Neurosurgical Society Pub Date : 2024-03-01 Epub Date: 2023-10-06 DOI: 10.3340/jkns.2023.0133

Yung Ki Park, Byul-Hee Yoon, Yu Deok Won, Jae Hoon Kim, Hee In Kang

{"title":"Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea.","authors":"Yung Ki Park, Byul-Hee Yoon, Yu Deok Won, Jae Hoon Kim, Hee In Kang","doi":"10.3340/jkns.2023.0133","DOIUrl":"10.3340/jkns.2023.0133","url":null,"abstract":"Objective: The treatment paradigm for acute ischemic stroke has undergone several major changes in the past decade, contributing to improved patient prognosis in clinical practice. However, the extent to which these changes have affected patient prognosis in the real-world is yet to be clarified. This study aimed to evaluate the real-world impact of modern reperfusion therapy for acute ischemic stroke using data from the National Health Insurance Service in Korea.Methods: This study included patients aged 18-80 years who were admitted via the emergency room with an I63 code between 2011 and 2020. The rates of intravenous thrombolysis use and endovascular treatment according to the year of admission were investigated. Furthermore, the rates of decompressive craniectomy and 3-month mortality were also analyzed. The 10-year observational period was divided into three periods based on the 2015 guideline change as follows : prior, 2011-2014; transitional, 2015-2016; and modern, 2017-2020.Results: A total of 307117 patients (mean age, 65.7±10.9 years) were included, and most patients were male (59.7%). The rate of endovascular treatment gradually increased during the study period from 0.71% in the prior period to 1.32% in the transitional period and finally to 1.85% in the modern period. Meanwhile, the 3-month mortality rate gradually decreased from 4.78% in the prior period to 4.03% in the transitional period and to 3.71% in the modern period.Conclusion: In Korea, the mortality rate decreased as the rate of modern reperfusion therapy increased in patients with acute ischemic stroke. Overall, technical and scientific advances in reperfusion therapy have improved the outcome of patients with acute ischemic stroke in Korea.","PeriodicalId":16283,"journal":{"name":"Journal of Korean Neurosurgical Society","volume":" ","pages":"186-193"},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10924908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0