Journal of Medical and Health Studies最新文献_第2页

Relationship between Serum Glial Fibrillary Acidic Protein and Neurogranin Levels and Cognition in Multiple Sclerosis 多发性硬化症患者血清胶质纤维酸性蛋白和神经粒蛋白水平与认知能力之间的关系

Journal of Medical and Health Studies Pub Date : 2024-02-05 DOI: 10.32996/jmhs.2024.5.1.6

M. Alpua, U. Kisa, Ercan Tekin, Ufuk Ergun

{"title":"Relationship between Serum Glial Fibrillary Acidic Protein and Neurogranin Levels and Cognition in Multiple Sclerosis","authors":"M. Alpua, U. Kisa, Ercan Tekin, Ufuk Ergun","doi":"10.32996/jmhs.2024.5.1.6","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.6","url":null,"abstract":"Multiple sclerosis is an inflammatory neurodegenerative disorder, and cognitive problems occur in the early and late phases of the disease. The purpose of this study was to investigate the relationship between serum glial fibrillary acidic protein and neurogranin levels and cognition in patients with multiple sclerosis (MS). Twenty-three patients and 25 healthy controls were included in the study. Serum glial fibrillary acidic protein (GFAP) and neurogranin (NRGN) levels were determined on blood samples from patients and controls. Disease duration and EDSS scores of patients were recorded, and the Montreal Cognitive Assessment (MOCA) scale was used for cognitive assessment. There was no statistically significant difference between the two groups in terms of serum NRGN and GFAP levels. MOCA scores were lower in the patient group than in the healthy control group. No statistically significant correlation was found between NRGN and GFAP serum levels and MOCA scores. Our study showed that there was no statistically significant association between serum NRGN and GFAP levels and cognition in MS patients. This study is the first to examine serum GFAP and NRGN levels in the context of cognition in MS.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139862696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug Consumption: Analyzing A Series of Urine Samples from Algiers Addicts by GC-MS Low Cost Derivatization Method 毒品消费：用 GC-MS 低成本衍生化方法分析阿尔及尔吸毒者的一系列尿液样本

Journal of Medical and Health Studies Pub Date : 2024-01-25 DOI: 10.32996/jmhs.2024.5.1.5

Lokmane DALI BRAHAM, Salma Kaddour, Asma Brahimi, Souhila Amokrane

{"title":"Drug Consumption: Analyzing A Series of Urine Samples from Algiers Addicts by GC-MS Low Cost Derivatization Method","authors":"Lokmane DALI BRAHAM, Salma Kaddour, Asma Brahimi, Souhila Amokrane","doi":"10.32996/jmhs.2024.5.1.5","DOIUrl":"https://doi.org/10.32996/jmhs.2024.5.1.5","url":null,"abstract":"The complex and evolving landscape of drug addiction poses significant public health challenges in Algiers, Algeria. With growing concerns about drug addiction and its associated consequences, it becomes imperative to comprehensively understand drug consumption patterns among individuals grappling with addiction in this region. Drug addiction is a multifaceted issue influenced by various factors such as drug availability, sociodemographic characteristics, and personal choices. The prevalence of drug addiction continues to rise, warranting a thorough examination of the specific substances that dominate the local addiction landscape. A descriptive retrospective analytical study was conducted, analyzing 92 cases of drug consumption profiles among addicts in the Algerian province of Algiers. Urine samples collected between January 1, 2020, and October 15, 2022, from drug-addicted patients in Algiers, were examined using Gas Chromatography-Mass Spectrometry (GC-MS). The meticulous analysis of this diverse population revealed that THC and pregabalin are the two most frequently consumed substances, often used together in poly-drug combinations. Surprisingly, there is a notable prevalence of opioid consumption, especially within families, raising concerns about a potential opioid crisis in Algiers.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"110 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140495708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paraneoplastic Syndrome Associated Immune Complications: A Narrative Review of the Literature 副肿瘤综合征相关免疫并发症：文献综述

Journal of Medical and Health Studies Pub Date : 2024-01-04 DOI: 10.32996/jmhs.2024.5.1.2

Maheshwari Nallur Siddaraju, Shivani B. Sonan, Kadeeja K S, Priscilla Brown, Ayushman Gupta, Mohammed Shafeay, Gowrishankar Palaniswamy, Keval B. Patel, Julian Jude J. Ayroor, Ali Haider

引用次数: 0

Why Face Masks Should not be Imposed on the Public Again: A Review Article 为什么不应再次向公众强加口罩？评论文章

Journal of Medical and Health Studies Pub Date : 2023-12-15 DOI: 10.32996/jmhs.2023.4.6.14

Ahmad Alrasheedi

{"title":"Why Face Masks Should not be Imposed on the Public Again: A Review Article","authors":"Ahmad Alrasheedi","doi":"10.32996/jmhs.2023.4.6.14","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.14","url":null,"abstract":"Viral epidemics of acute respiratory infections pose a global threat. Influenza outbreaks occur almost every year. Specifically, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), emerged in late 2019. This unprecedented event resulted in many countries requiring masks in public spaces to contain the spread of SARS-CoV-2. However, the early and previous systematic reviews of randomized controlled trials (RCTs) found that medical/surgical masks did not appear to reduce respiratory viral infections. Also, N95 respirators did not provide superior protection over surgical masks against viral infections or influenza-like infections among healthcare workers (HCWs), although N95 respirators theoretically provide better protection. This led to the recommendation not to wear facemasks as potential benefits are limited, and there is a risk of self-contamination if misused. However, with the ongoing spread of SARS-CoV-2, several health authorities suddenly shifted their recommendations and advised the general public to wear masks, with some governments even mandating it. By July 2023, the health-protective benefits of wearing facemasks are still conflicting, and debate over the idea of a mask mandate is ongoing. Therefore, this review aims to discuss ten reasons why face masks should not be imposed on the public again, which include the functional weaknesses of facemasks, lack of justification for the sudden change in the recommendations during the COVID-19 pandemic, the effectiveness of facemasks in the community and among HCWs based on the systematic reviews of the RCTs, their effectiveness based on the RCTs, the effectiveness of N95 respirators versus surgical masks in protecting from acute respiratory infection based on the systematic reviews, their potential harms, the poor quality of most masks used by the public, their misuse, the trajectory of the COVID-19 pandemic despite masking, and the importance of acknowledgment of the rights of people in wearing masks or not.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"43 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Obesity and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: An Updated Systematic Review 心脏手术患者肥胖与术后心房颤动之间的关系：最新系统回顾

Journal of Medical and Health Studies Pub Date : 2023-12-10 DOI: 10.32996/jmhs.2023.4.6.13

Syed Shireen Andrabi, Keshvi V. Shanghavi, MD Anum Haider, Poojitha Jaladi, Sai Tejeswi Godavarr, Smruthi Panchagnula, Karoona Bai, Lavanya Nagarajan, Akhilesh Sharma, Arjun Jayakumar, Waleed Razzaq, Ali Haider

{"title":"Association Between Obesity and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: An Updated Systematic Review","authors":"Syed Shireen Andrabi, Keshvi V. Shanghavi, MD Anum Haider, Poojitha Jaladi, Sai Tejeswi Godavarr, Smruthi Panchagnula, Karoona Bai, Lavanya Nagarajan, Akhilesh Sharma, Arjun Jayakumar, Waleed Razzaq, Ali Haider","doi":"10.32996/jmhs.2023.4.6.13","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.13","url":null,"abstract":"Postoperative atrial fibrillation (POAF) is a frequent and severe complication following cardiac surgery. While obesity is established as a risk factor for atrial fibrillation (AF) in non-surgical settings, its role in the postoperative period is still debated. This systematic review aims to assess the relationship between obesity and POAF in patients undergoing cardiac surgery. A comprehensive literature search was conducted in PubMed, Embase, Web of Science, and Cochrane Library, focusing on randomized controlled trials (RCTs) published until June 2023. Data were extracted independently by two authors and assessed using the Cochrane Risk of Bias Tool (RoB2). From an initial search of 1,284 articles, 11 studies met the inclusion criteria, with a range of sample sizes between 300 and 5,000 patients. The incidence of POAF in obese patients ranged from 30% to 54%, compared to 20% to 46% in non-obese patients. Five studies concluded that obesity was a significant risk factor for POAF, whereas four found no statistically significant relationship, and two reported an \"obesity paradox,\" where obesity appeared protective or neutral regarding POAF risk. Our review provides evidence regarding obesity developing POAF after cardiac surgery.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"770 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Treatment of Closed Fracture of the Anterior Wall of the Frontal Sinus with Displacement by the ORIF Technique using a Titanium Plate: A Case Report 使用钛板的 ORIF 技术治疗额窦前壁闭合性骨折伴移位：病例报告

Journal of Medical and Health Studies Pub Date : 2023-12-09 DOI: 10.32996/jmhs.2023.4.6.12

Dmytro Zabolotnyi, Vladislav Nesterchuk, Oleksandr Kostiuchenko, O. Kvasha

{"title":"Surgical Treatment of Closed Fracture of the Anterior Wall of the Frontal Sinus with Displacement by the ORIF Technique using a Titanium Plate: A Case Report","authors":"Dmytro Zabolotnyi, Vladislav Nesterchuk, Oleksandr Kostiuchenko, O. Kvasha","doi":"10.32996/jmhs.2023.4.6.12","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.12","url":null,"abstract":"Fractures associated with anterior and posterior frontal sinus walls are among the most challenging cranio-maxillofacial injuries. These represent a major emergency, having a potentially severe clinical picture, with intracranial hemorrhage, cerebrospinal fluid leak, meningeal lesions, pneumocephalus, contusion or laceration of the brain matter, coma, and in some cases, death. In this article, we present the case of a 32-year-old patient with the diagnosis of: Closed fracture of the anterior wall of the frontal sinus with displacement, fracture of the posterior wall of the frontal sinus without displacement and impairment of the upperface bone architecture. Despite the severity and complexity of the case, early initiation of correct ENT surgery, using ORIF (open fracture alignment and internal fixation) technique, led to the successful reconstruction and redimensioning of upperface architecture and to the restoration of the patient’s physiognomy. This article describes a case report on the use of titanium plates for the reconstruction of the upper aesthetic area of the face. The article also describes the use of the ORIF technique, its description, and its advantages, as well as a literature review in order to show its advantages in the avoidance of postoperative complications. The purpose of the work is to describe a new technique that helps to avoid aesthetic and functional complications in the future, which will be useful to otorhinolaryngologists and maxillofacial surgeons.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of Determining Morbidity and Mortality Codes for Covid-19 Patients at Imelda Hospital Medan 棉兰伊梅尔达医院确定 Covid-19 患者发病率和死亡率代码概览

Journal of Medical and Health Studies Pub Date : 2023-12-08 DOI: 10.32996/jmhs.2023.4.6.11

Esraida Simanjuntak, Siti Permata, Sari Lubis, Marta Simanjuntak, Johanna Christy

{"title":"Overview of Determining Morbidity and Mortality Codes for Covid-19 Patients at Imelda Hospital Medan","authors":"Esraida Simanjuntak, Siti Permata, Sari Lubis, Marta Simanjuntak, Johanna Christy","doi":"10.32996/jmhs.2023.4.6.11","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.11","url":null,"abstract":"The COVID-19 morbidity code is used to determine the primary condition and secondary condition of a COVID-19 patient condition obtained during an episode of health care that is very important in hospital reporting, where from the morbidity data, the number of patients discharged (live and dead) and the formulation and health programs is obtained. At the same time, the COVID-19 death code is the main source for filling out patient death certificates. Death certificates will be used to report deaths, which are very useful for hospitals to evaluate service quality and the need for medical personnel and equipment to determine the morbidity and mortality code in COVID-19 patients at the Imelda Indonesian Workers General Hospital Medan in 2021. The method used in this research is observation and structured interviews. The results in this study are the number of patients from January to March 2021 who confirmed COVID-19, including 44 morbidity patients and 8 mortality patients, with suspected COVID-19 including 31 mortality patients. COVID-19 health workers, however, do not implement mortality coding for COVID-19 patients. The Imelda General Hospital of Indonesian Workers carries out the provision of a morbidity code for COVID-19 patients but does not carry out the provision of a mortality code for COVID-19 patients.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138587547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intimate Partner Violence among College Women: A Single-Centred Cross-Sectional Study 女大学生中的亲密伴侣暴力：单中心横断面研究

Journal of Medical and Health Studies Pub Date : 2023-12-05 DOI: 10.32996/jmhs.2023.4.6.9

Canan Tuz Yilmaz, Ayşe Selda Tekiner

引用次数: 0

Analysis of Waist-to-Hip and Height Ratio on the Risk of Cardiovascular Disease 腰臀比和身高对心血管疾病风险的影响分析

Journal of Medical and Health Studies Pub Date : 2023-12-05 DOI: 10.32996/jmhs.2023.4.6.10

Annisaa Fitrah Umara, Karina Megasari Winahyu, Imas Yoyoh

{"title":"Analysis of Waist-to-Hip and Height Ratio on the Risk of Cardiovascular Disease","authors":"Annisaa Fitrah Umara, Karina Megasari Winahyu, Imas Yoyoh","doi":"10.32996/jmhs.2023.4.6.10","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.10","url":null,"abstract":"Cardiovascular disease (CVD) remains a major global health issue affecting people of all ages, including those in their prime of life. Even though there are several risk factors for CVD, prevention depends on early identification. Moreover, Waist-to-Hip Ratio (WHR) and Waist-to-Height Ratio (WHtR) are predictors of cardiovascular disease that are easy to do and can be used for early detection of CVD. The aim of this study was to analyze the relationship between WHR and WHtR with the risk of CVD in the productive age group. The study used a cross-sectional design and purposive sampling involving 150 respondents aged 25-64. WHR and WHtR measurements as predictors and CVD risk scores were calculated using the Jakarta Cardiovascular Score (JCS). This study was analyzed with the Spearman's Rho test. The majority of women's WHR increased with low CVD risk, the majority of men's WHR increased with high CVD risk, and the majority of WHtR in both men and women increased with low CVD risk. There is a relationship between WHR and the risk of CVD with JCS in productive age (p=0.000, r = 0.535) and a relationship between WHtR and the risk of CVD with JCS (p=0.000, r = 0.332). The study suggests that WHR and WHtR are significant measurements in cardiovascular assessment to prevent cardiovascular disease in the productive age group.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"28 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138601102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution of Genetic Polymorphisms of the Agt M235t Gene in Hypertension Patients Taking Angiotensin-Converting Enzyme Inhibitor (ACEi) Drugs in Indonesia 印度尼西亚服用血管紧张素转换酶抑制剂 (ACEi) 药物的高血压患者的 Agt M235t 基因多态性分布情况

Journal of Medical and Health Studies Pub Date : 2023-12-03 DOI: 10.32996/jmhs.2023.4.6.8

Andi Thafida Khalisa, W. Widyati, S. Tuba

{"title":"Distribution of Genetic Polymorphisms of the Agt M235t Gene in Hypertension Patients Taking Angiotensin-Converting Enzyme Inhibitor (ACEi) Drugs in Indonesia","authors":"Andi Thafida Khalisa, W. Widyati, S. Tuba","doi":"10.32996/jmhs.2023.4.6.8","DOIUrl":"https://doi.org/10.32996/jmhs.2023.4.6.8","url":null,"abstract":"The condition of high blood pressure is characterized by a systolic pressure (TDS) ≤140 mmHg and a diastolic pressure (TDD) ≥ 90 mmHG. The M235T gene polymorphism inside the AGT gene has the potential to serve as a biomarker for the early identification and detection of hypertensive disease. The presence of the TT genotype and the T allele in the AGT M235T gene is associated with an increased susceptibility to hypertension. Furthermore, the study revealed a notable disparity in the occurrence of the AGTM235T variant (rs699) between individuals with hypertension and the control group. The objective of the study is to see the distribution of genetic polymorphism of AGT M235T gene in hypertensive patients taking Angiotensin-Converting Enzyme Inhibitor (ACEi) drugs. This study used the Narrative Review Method with a comprehensive systematic review of articles that have been published from 2013 to 2023 in English using the MEDLINE (PubMed), Google Scholar, and Cochrane Library databases. The AGT M235T polymorphism has been found to have a significant association with the use of ACEi medications in individuals diagnosed with hypertension, as indicated by several investigations. This study exhibits certain limitations and needs additional prospective investigations to corroborate the findings. In some studies, AGT M235T polymorphism in hypertension patients has a strong correlation with ACEi drugs.","PeriodicalId":162243,"journal":{"name":"Journal of Medical and Health Studies","volume":"100 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138605783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0