Drug Consumption: Analyzing A Series of Urine Samples from Algiers Addicts by GC-MS Low Cost Derivatization Method

Lokmane DALI BRAHAM, Salma Kaddour, Asma Brahimi, Souhila Amokrane
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Abstract

The complex and evolving landscape of drug addiction poses significant public health challenges in Algiers, Algeria. With growing concerns about drug addiction and its associated consequences, it becomes imperative to comprehensively understand drug consumption patterns among individuals grappling with addiction in this region. Drug addiction is a multifaceted issue influenced by various factors such as drug availability, sociodemographic characteristics, and personal choices. The prevalence of drug addiction continues to rise, warranting a thorough examination of the specific substances that dominate the local addiction landscape. A descriptive retrospective analytical study was conducted, analyzing 92 cases of drug consumption profiles among addicts in the Algerian province of Algiers. Urine samples collected between January 1, 2020, and October 15, 2022, from drug-addicted patients in Algiers, were examined using Gas Chromatography-Mass Spectrometry (GC-MS). The meticulous analysis of this diverse population revealed that THC and pregabalin are the two most frequently consumed substances, often used together in poly-drug combinations. Surprisingly, there is a notable prevalence of opioid consumption, especially within families, raising concerns about a potential opioid crisis in Algiers.
毒品消费:用 GC-MS 低成本衍生化方法分析阿尔及尔吸毒者的一系列尿液样本
在阿尔及利亚阿尔及尔,复杂而不断变化的吸毒问题给公共卫生带来了巨大挑战。随着人们对吸毒成瘾及其相关后果的日益关注,全面了解该地区吸毒成瘾者的毒品消费模式已成为当务之急。吸毒成瘾是一个多方面的问题,受毒品供应、社会人口特征和个人选择等多种因素的影响。吸毒成瘾的流行率持续上升,因此有必要对主导当地吸毒成瘾情况的特定物质进行彻底研究。我们进行了一项描述性回顾分析研究,分析了阿尔及利亚阿尔及尔省 92 例吸毒者的药物消费概况。研究人员使用气相色谱-质谱法(GC-MS)对 2020 年 1 月 1 日至 2022 年 10 月 15 日期间收集的阿尔及尔吸毒患者的尿液样本进行了检测。对这一不同人群进行的细致分析表明,四氢大麻酚和普瑞巴林是最常服用的两种药物,经常在多种药物组合中同时使用。令人惊讶的是,阿片类药物的消费非常普遍,尤其是在家庭中,这引起了人们对阿尔及尔潜在阿片类药物危机的担忧。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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