副肿瘤综合征相关免疫并发症:文献综述

Maheshwari Nallur Siddaraju, Shivani B. Sonan, Kadeeja K S, Priscilla Brown, Ayushman Gupta, Mohammed Shafeay, Gowrishankar Palaniswamy, Keval B. Patel, Julian Jude J. Ayroor, Ali Haider
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引用次数: 0

摘要

副肿瘤综合征发生在癌症患者身上,是由于他们的免疫反应发生了改变。导致副肿瘤综合征发生的因素有多种,其中包括异常细胞因子的存在会对全身造成广泛影响。副肿瘤综合征可能会在癌症确诊前出现在患者身上,因此,了解副肿瘤综合征至关重要,因为这将有助于实现及时诊断,从而提高治疗机会。它与患者的多种并发症/表现有关。在本综述中,我们将讨论与副肿瘤综合征相关的几种并发症,包括高凝状态、静脉血栓栓塞、动脉血栓栓塞、血栓性微血管病、弥散性血管内凝血和恶性肿瘤相关的非细菌性血栓性心内膜炎。虽然其中一些病例很少见,但临床医生必须对每种病例有所了解,以便有时间进行处理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paraneoplastic Syndrome Associated Immune Complications: A Narrative Review of the Literature
Paraneoplastic syndromes occur in cancer patients due to an alteration in their immune response. There are several factors that may result in the occurrence of paraneoplastic syndrome, including the presence of abnormal cytokines that cause widespread effects throughout the body. The paraneoplastic syndrome may be present in patients before a diagnosis of cancer, and thus, understanding it is crucial as it will help achieve a timely diagnosis, which may aid in improving the chance of treatment. It is associated with several complications/presentations in patients. In this review, we will discuss several paraneoplastic syndrome associated complications, including hypercoagulable state, venous thromboembolism, arterial thromboembolism, thrombotic microangiopathy, disseminated intravascular coagulation, and malignancy associated non-bacterial thrombotic endocarditis. Although some are rare, it is vital for clinicians to have a knowledge of each to allow time for management.
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