{"title":"Editorial for \"<sup>19</sup>Fluorine-MRI Based Longitudinal Immuno-Microenvironment-Monitoring for Pancreatic Cancer\".","authors":"Emily Hoffmann, Cornelius Faber","doi":"10.1002/jmri.29593","DOIUrl":"https://doi.org/10.1002/jmri.29593","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial for \"Reliability of In Vivo Creatine-Weighted Chemical Exchange Saturation Transfer (CrCEST) MRI in Calf Skeletal Muscle of Healthy Volunteers at 3 T\".","authors":"Grace McIlvain","doi":"10.1002/jmri.29578","DOIUrl":"https://doi.org/10.1002/jmri.29578","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Temel Tirkes, Dhiraj Yadav, Darwin L Conwell, Xuandong Zhao, Anil K Dasyam, Vivek Gowdra Halappa, Aashish Patel, Zarine K Shah, Jordan Swensson, Naoki Takahashi, Sudhakar Venkatesh, Ashley Wachsman, Liang Li, Kristofer Jennings, Yunlong Yang, Phil A Hart, Stephen J Pandol, Walter G Park, Santhi Swaroop Vege, Mark Topazian, Paul R Territo, Scott A Persohn, Dana K Andersen, Evan L Fogel
{"title":"Multiparametric MRI Scoring System of the Pancreas for the Diagnosis of Chronic Pancreatitis.","authors":"Temel Tirkes, Dhiraj Yadav, Darwin L Conwell, Xuandong Zhao, Anil K Dasyam, Vivek Gowdra Halappa, Aashish Patel, Zarine K Shah, Jordan Swensson, Naoki Takahashi, Sudhakar Venkatesh, Ashley Wachsman, Liang Li, Kristofer Jennings, Yunlong Yang, Phil A Hart, Stephen J Pandol, Walter G Park, Santhi Swaroop Vege, Mark Topazian, Paul R Territo, Scott A Persohn, Dana K Andersen, Evan L Fogel","doi":"10.1002/jmri.29594","DOIUrl":"10.1002/jmri.29594","url":null,"abstract":"<p><strong>Background: </strong>Ductal features alone may not offer high diagnostic sensitivity or most accurate disease severity of chronic pancreatitis (CP).</p><p><strong>Purpose: </strong>Diagnose CP based on multiparametric MRI and MRCP features.</p><p><strong>Study type: </strong>Prospective.</p><p><strong>Population: </strong>Between February 2019 and May 2021, 46 control (23 males, 49.3 ± 14.1 years), 45 suspected (20 males, 48.7 ± 12.5 years), and 46 definite (20 males, 53.7 ± 14.6 years) CP patients were enrolled at seven hospitals enrolled in the MINIMAP study. CP classification was based on imaging findings and clinical presentation.</p><p><strong>Field strength and sequences: </strong>1.5 T. T<sub>1</sub>-weighted (T<sub>1</sub>W) spoiled gradient echo, T1 map with variable flip angle, dual-echo Dixon, secretin-enhanced MRCP before and after secretin infusion.</p><p><strong>Assessment: </strong>Dual-echo fat fraction (FF), T<sub>1</sub> relaxation time, extracellular volume (ECV), T<sub>1</sub> signal intensity ratio of the pancreas to the spleen (T<sub>1</sub> score), arterial-to-venous enhancement ratio (AVR), pancreatic tail diameter (PTD), pancreas volume, late gadolinium enhancement, pancreatic ductal elasticity (PDE), and duodenal filling grade of secretin-enhanced MRCP were measured.</p><p><strong>Statistical tests: </strong>Logistic regression analysis generated CP-MRI and secretin-enhanced CP-SMRI scores. Receiver operating characteristics analysis was used to differentiate definite CP from control. Interobserver agreement was assessed using Lin's concordance correlation coefficient.</p><p><strong>Results: </strong>Compared to control, definite CP cohort showed significantly higher dual-echo FF (7% vs. 11%), lower AVR (1.35 vs. 0.85), smaller PTD (2.5 cm vs. 1.95 cm), higher ECV (28% vs. 38%), and higher incidence of PDE loss (6.5% vs. 50%). With the cut-off of >2.5 CP-MRI score (dual-echo FF, AVR, and PTD) and CP-SMRI score (dual-echo FF, AVR, PTD, and PDE) had cross-validated area under the curves of 0.84 (sensitivity 87%, specificity 68%) and 0.86 (sensitivity 89%, specificity 67%), respectively. Interobserver agreement for both CP-MRI and CP-SMRI scores was 0.74.</p><p><strong>Conclusion: </strong>The CP-MRI and CP-SMRI scores yielded acceptable performance and interobserver agreement for the diagnosis of CP.</p><p><strong>Evidence level: </strong>1 TECHNICAL EFFICACY: Stage 2.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial for \"Quantitative Analysis of Small Intestinal Motility in 3D Cine-MRI Using Centerline-Aware Motion Estimation.","authors":"Aysegul Sagir Kahraman, Bayram Kahraman","doi":"10.1002/jmri.29596","DOIUrl":"https://doi.org/10.1002/jmri.29596","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial for \"Spontaneous Brain Activity Abnormalities in Patients With Temporal Lobe Epilepsy: A Meta-Analysis of 1474 Patients\".","authors":"Elza Azri Othman","doi":"10.1002/jmri.29570","DOIUrl":"https://doi.org/10.1002/jmri.29570","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shu Xiao, Zibin Yang, Zitao Lin, Liqing Chen, Weiming Liao, Jurong Wang, Cuihua Gao, Jianjun Lu, Yang Song, Sulian Su, Guihua Jiang
{"title":"Spontaneous Brain Activity Abnormalities in Patients With Temporal Lobe Epilepsy: A Meta-Analysis of 1474 Patients.","authors":"Shu Xiao, Zibin Yang, Zitao Lin, Liqing Chen, Weiming Liao, Jurong Wang, Cuihua Gao, Jianjun Lu, Yang Song, Sulian Su, Guihua Jiang","doi":"10.1002/jmri.29568","DOIUrl":"https://doi.org/10.1002/jmri.29568","url":null,"abstract":"<p><strong>Background: </strong>Abnormalities in resting-state functional brain activity have been detected in patients with temporal lobe epilepsy (TLE). The results of individual neuroimaging studies of TLE, however, are frequently inconsistent due to small and heterogeneous samples, analytical flexibility, and publication bias toward positive findings.</p><p><strong>Purpose: </strong>To investigate the most consistent regions of resting-state functional brain activity abnormality in patients with TLE through a quantitative meta-analysis of published neuroimaging data.</p><p><strong>Study type: </strong>Meta-analysis.</p><p><strong>Subjects: </strong>Exactly 1474 TLE patients (716 males and 758 females) from 31 studies on resting-state functional brain activity were included in this study.</p><p><strong>Field strength/sequence: </strong>Studies utilizing 1.5 T or 3 T MR scanners were included for meta-analysis. Resting-state functional MRI using gradient echo-planar imaging, T1-weighted imaging.</p><p><strong>Assessment: </strong>PubMed, Web of Science, Chinese National Knowledge Infrastructure, and WanFang databases were searched to identify studies investigating amplitude of low-frequency fluctuation (ALFF), fractional ALFF (fALFF), and regional homogeneity (ReHo) at the whole-brain level between patients with TLE and healthy controls (HCs).</p><p><strong>Statistical tests: </strong>Seed-based d Mapping with Permutation of Subject Images, standard randomization tests and meta-regression analysis were used. Results were significant if P < 0.05 with family-wise error corrected.</p><p><strong>Results: </strong>Patients with TLE displayed resting-state functional brain activity which was a significant increase in the right hippocampus, and significant decrease in the right angular gurus and right precuneus. Additionally, the meta-regression analysis demonstrated that age (P = 0.231), sex distribution (P = 0.376), and illness duration (P = 0.184), did not show significant associations with resting state functional brain activity in patients with TLE.</p><p><strong>Data conclusion: </strong>Common alteration patterns of spontaneous brain activity were identified in the right hippocampus and default-model network regions in patients with TLE. These findings may contribute to understanding of the underlying mechanism for potentially effective intervention of TLE.</p><p><strong>Level of evidence: 1: </strong></p><p><strong>Technical efficacy stage: </strong>Stage 2.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to Letter to Editor Regarding \"Influence of Morphological Changes on Dural Venous Sinuses Hemodynamics\".","authors":"Chihang Dai, Zhenchang Wang, Pengfei Zhao","doi":"10.1002/jmri.29591","DOIUrl":"https://doi.org/10.1002/jmri.29591","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan J Cardona, Aaron S Dumont, Joe Iwanaga, R Shane Tubbs
{"title":"Influence of Morphological Changes on Dural Venous Sinuses Hemodynamics.","authors":"Juan J Cardona, Aaron S Dumont, Joe Iwanaga, R Shane Tubbs","doi":"10.1002/jmri.29590","DOIUrl":"https://doi.org/10.1002/jmri.29590","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial for \"Assessment of Tumor Cell Invasion and Radiotherapy Response in Experimental Glioma by Magnetic Resonance Elastography\".","authors":"James R Ewing","doi":"10.1002/jmri.29577","DOIUrl":"https://doi.org/10.1002/jmri.29577","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kasturee Chakraborty, Ritambhar Burman, Sabah Nisar, Saorla Miller, Zachary Loschinskey, Shengjie Wu, Yimei Li, Asim K Bag, Ayaz Khan, Chelsea Goodenough, Neil Wilson, Mohammad Haris, Shana E McCormack, Ravinder Reddy, Kirsten Ness, Richard Finkel, Puneet Bagga
{"title":"Reliability of In Vivo Creatine-Weighted Chemical Exchange Saturation Transfer (CrCEST) MRI in Calf Skeletal Muscle of Healthy Volunteers at 3 T.","authors":"Kasturee Chakraborty, Ritambhar Burman, Sabah Nisar, Saorla Miller, Zachary Loschinskey, Shengjie Wu, Yimei Li, Asim K Bag, Ayaz Khan, Chelsea Goodenough, Neil Wilson, Mohammad Haris, Shana E McCormack, Ravinder Reddy, Kirsten Ness, Richard Finkel, Puneet Bagga","doi":"10.1002/jmri.29566","DOIUrl":"10.1002/jmri.29566","url":null,"abstract":"<p><strong>Background: </strong>Skeletal muscle mitochondrial oxidative phosphorylation (mtOXPHOS) is important for ATP generation and its dysfunction leads to exercise intolerance. Phosphorus magnetic resonance spectroscopy (<sup>31</sup>P-MRS) is a useful, noninvasive technique for mtOXPHOS assessment but has limitations. Creatine-weighted chemical exchange saturation transfer (CrCEST) MRI is a potential alternative to assess muscle bioenergetics.</p><p><strong>Purpose: </strong>To evaluate the interscan repeatability, intra- and interobserver reproducibility of CrCEST during mild plantar flexion exercise.</p><p><strong>Study type: </strong>Retrospective.</p><p><strong>Subjects: </strong>Twenty healthy volunteers (age 37.6 ± 12.4 years, 11 females).</p><p><strong>Field strength/sequence: </strong>3 T/CEST imaging using gradient echo readout.</p><p><strong>Assessment: </strong>τCrCEST (postexercise Cr recovery time) was assessed in two scans for each participant, following mild plantar flexion exercises targeting the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (Sol) muscles. Three observers measured τCrCEST for interobserver reproducibility. Three readings by one observer were used to measure intraobserver reproducibility. Two scans were used for within-participant interscan repeatability.</p><p><strong>Statistical tests: </strong>Paired t tests, intraclass correlation coefficient (ICC), and Pearson correlation were conducted. Bland-Altman plots were used to analyze the interobserver variability. A P-value of 0.05 was considered statistically significant.</p><p><strong>Results: </strong>There was excellent intra- (ICC <math> <semantics><mrow><mo>∈</mo> <mfenced><mrow><mn>0.94</mn> <mo>-</mo> <mn>0.98</mn></mrow> </mfenced> </mrow> <annotation>$$ in left[0.94-0.98right] $$</annotation></semantics> </math> ) and interobserver (ICC <math> <semantics><mrow><mo>∈</mo> <mfenced><mrow><mn>0.9</mn> <mo>-</mo> <mn>0.98</mn></mrow> </mfenced> </mrow> <annotation>$$ in left[0.9-0.98right] $$</annotation></semantics> </math> ) reproducibility, with moderate interscan repeatability for τCrCEST in LG and MG (ICC <math> <semantics><mrow><mo>∈</mo> <mfenced><mrow><mn>0.54</mn> <mo>-</mo> <mn>0.74</mn></mrow> </mfenced> </mrow> <annotation>$$ in left[0.54-0.74right] $$</annotation></semantics> </math> ) and poor-to-moderate interscan repeatability in Sol (ICC <math> <semantics><mrow><mo>∈</mo> <mfenced><mrow><mn>0.24</mn> <mo>-</mo> <mn>0.53</mn></mrow> </mfenced> </mrow> <annotation>$$ in left[0.24-0.53right] $$</annotation></semantics> </math> ). Excellent interobserver reproducibility was confirmed by Bland-Altman plots (fixed bias P-value <math> <semantics><mrow><mo>∈</mo> <mfenced><mrow><mn>0.08</mn> <mo>-</mo> <mn>0.87</mn></mrow> </mfenced> </mrow> <annotation>$$ in left[0.08-0.87right] $$</annotation></semantics> </math> ).</p><p><strong>Data conclusion: </strong>CrCEST MRI shows promise in assessing muscle bioenergetics by evaluati","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}