Journal of Magnetic Resonance Imaging最新文献

{"title":"Editorial for \"Associations of Postencephalitic Epilepsy Using Multi-Contrast Whole Brain MRI: A Large Self-Supervised Vision Foundation Model Strategy\".","authors":"Barbara A K Kreilkamp","doi":"10.1002/jmri.29751","DOIUrl":"https://doi.org/10.1002/jmri.29751","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143501963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging.","authors":"Vanessa M Diamond, Laura C Bell, Jeffrey N Bone, Bastiaan Driehuys, Martha Menchaca, Giles Santyr, Sarah Svenningsen, Robert P Thomen, Helen Marshall, Laurie J Smith, Guilhem J Collier, Jim M Wild, Jason C Woods, Sean B Fain, Rachel L Eddy, Jonathan H Rayment","doi":"10.1002/jmri.29746","DOIUrl":"https://doi.org/10.1002/jmri.29746","url":null,"abstract":"<p><p>Hyperpolarized (HP) gas pulmonary MR ventilation images are typically quantified using ventilation defect percent (VDP); however, the test-retest variability of VDP has not been systematically established in multi-center trials. Herein, we perform a systematic review of the test-retest literature on the variability of VDP, and similar metrics, generated from HP MRI. This review utilizes the Medline, EMBASE, and EBM Reviews databases and includes studies that assessed the variability of HP MRI VDP. The protocol was registered to PROSPERO: CRD42022328535. Imaging techniques and statistical analysis characteristics were extracted and used to group studies to evaluate the overall ability to pool data across grouped studies. The ability to pool data to provide systematic evidence was assessed using a modified COSMIN tool. A total of 22 studies with 37 distinct aims for repeated HP MRI acquisition or quantification were included. Studies were grouped into six categories based on HP gas and analysis type: repeated imaging (¹²⁹Xe n = 13, ³He n = 12), interobserver repeated analysis (¹²⁹Xe n = 4, ³He n = 4) or intraobserver repeated analysis (¹²⁹Xe n = 1, ³He n = 2). Studies assessed variability using a variety of statistical tests including absolute difference, percent coefficient of variation, Bland-Altman limits of agreement, coefficient of reproducibility, or the intra-class correlation. Individual studies generally reported low variability of VDP (ICC range: 0.5-1.0; Bland-Altman bias range: -6.9-20%), but there was an overall inability to pool data and provide a meta-analysis due to methodological inconsistencies and small sample size. Overall, we found that VDP has low variability in most studies. However, inconsistent image acquisition and quantification methodologies between studies limits direct comparability and precludes grouping of study data for meta-analyses. Despite early efforts to standardize HP MRI acquisition, further work is necessary to standardize VDP quantification to allow broader validation and clinical implementation. Evidence Level: 2 Technical Efficacy: Stage 3.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of ¹H-MRS Using PRESS and MEGA-PRESS Techniques in the Preoperative Grading of Patients With Gliomas.","authors":"Maria L Brun-Vergara, Gerd Melkus, Santanu Chakraborty, Nader Zakhari, Carlos Torres, Fahad AlKherayf, Leya Ghantous, Rebecca Thornhill, John Woulfe, Gerard H Jansen, Thanh B Nguyen","doi":"10.1002/jmri.29690","DOIUrl":"https://doi.org/10.1002/jmri.29690","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Edited MRS technique such as MEshcher-GArwood Point RESolved Spectroscopy (MEGA-PRESS) can determine isocitrate dehydrogenase mutation (IDH) mutation status in patients with gliomas but its accuracy in assessing glioma grade has not yet been formally evaluated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To evaluate the diagnostic accuracy of metabolites such as lactate obtained from the PRESS and MEGA-PRESS sequences in the preoperative grading of glioma. To assess the prognostic value of those metabolite ratios in the overall survival of patients with gliomas.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study type: &lt;/strong&gt;Prospective.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Subjects: &lt;/strong&gt;Sixty-nine subjects with gliomas (16 grade 2, 21 grade 3, and 32 grade 4). Mean age was 50.5 ± 16.7 years; 38 were male and 31 were female.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Field strength/sequence: &lt;/strong&gt;3 T/MEGA-PRESS, PRESS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Assessment: &lt;/strong&gt;Single voxel PRESS and MEGA-PRESS spectra were obtained from tumors in patients undergoing preoperative MRI. Several tumor metabolites were measured from the PRESS, MEGA-PRESS edit-off, and difference spectra using LCModel (Linear Combination of Model Spectra) software. Diagnosis and glioma grading was done using the World Health Organization (WHO) 2016 classification. Overall survival was assessed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Statistical tests: &lt;/strong&gt;Diagnostic accuracy was measured using receiver-operating characteristic (ROC) curve. Univariate and multivariate Cox proportional hazards modeling was used for the assessment of prognostic factors for time to death.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the differentiation between low- vs. high-grade gliomas, tCr/tCho ratios obtained from PRESS and MEGA-PRESS sequences had similar accuracies (area under the ROC curves [AUCs] = 0.71) while Lac/NAA from PRESS had a lower accuracy (AUC = 0.65). The presence of a detectable 2-hydroxyglutarate peak on the difference spectrum was a favorable prognostic factor in univariate analysis (hazard ratio = 0.25, 95% confidence interval: 0.08-0.83). No other metabolite was found to be a significant prognostic factor in univariate and multivariate analyses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data conclusion: &lt;/strong&gt;Edited MRS can be used to detect metabolites which can help in the preoperative grading of gliomas and in determination of the overall survival. A separate PRESS acquisition is needed for lactate quantification.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Plain language summary: &lt;/strong&gt;Gliomas are brain tumors that vary in severity. This study explored the use of two advanced MR spectroscopy techniques (PRESS and MEGA-PRESS) in detecting tumor metabolites. The authors found that both techniques' choline/creatine ratio showed moderate accuracy in identifying high-grade gliomas. Lactate was better revealed with the PRESS technique and was associated with high-grade gliomas. They confirmed that the MEGA-PRESS technique allowed additional detection of 2-hydroxyglutarate in IDH-mutant gliomas, which was linked to better ","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current State of Evidence for Use of MRI in LI-RADS.","authors":"Ameya Madhav Kulkarni, Danielle Kruse, Kelly Harper, Eric Lam, Hoda Osman, Danyaal H Ansari, Umaseh Sivanesan, Mustafa R Bashir, Andreu F Costa, Matthew McInnes, Christian B van der Pol","doi":"10.1002/jmri.29748","DOIUrl":"https://doi.org/10.1002/jmri.29748","url":null,"abstract":"<p><p>The American College of Radiology Liver Imaging Reporting and Data System (LI-RADS) is the preeminent framework for classification and risk stratification of liver observations on imaging in patients at high risk for hepatocellular carcinoma. In this review, the pathogenesis of hepatocellular carcinoma and the use of MRI in LI-RADS is discussed, including specifically the LI-RADS diagnostic algorithm, its components, and its reproducibility with reference to the latest supporting evidence. The LI-RADS treatment response algorithms are reviewed, including the more recent radiation treatment response algorithm. The application of artificial intelligence, points of controversy, LI-RADS relative to other liver imaging systems, and possible future directions are explored. After reading this article, the reader will have an understanding of the foundation and application of LI-RADS as well as possible future directions.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Evaluating the Potential of Quantitative Susceptibility Mapping for Detecting Iron Deposition of Renal Fibrosis in a Rabbit Model\".","authors":"Alexey V Dimov, Martin R Prince","doi":"10.1002/jmri.29729","DOIUrl":"https://doi.org/10.1002/jmri.29729","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic Resonance Imaging for Dental Pulp Assessment: A Comprehensive Review.","authors":"Bing Han, Na Chen, Jin Luo, Farzaneh Afkhami, Ove A Peters, Xiaoyan Wang","doi":"10.1002/jmri.29742","DOIUrl":"https://doi.org/10.1002/jmri.29742","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) has recently emerged as a promising modality for dental applications, offering radiation-free imaging with superior soft tissue visualization capabilities compared to x-ray-based techniques such as spiral or cone beam computed tomography (CBCT). Conventional radiographic methods or CBCT cannot directly assess the condition of the dental pulp due to their primary focus on hard tissue visualization, whereas the dental pulp is primarily composed of connective tissue. Given the advantages of MRI in soft tissue imaging, this review aims to explore the current application of MRI for dental pulp tissue assessment. Relevant studies concerning the application of MRI for visualizing dental pulp were retrieved from databases including PubMed, Embase, and Scopus. The review explored and discussed the advancements in MRI hardware and software related to dental pulp visualization, as well as the advantages and limitations of MRI in dental pulp studies. Despite remaining limitations, such as scanning time and cost considerations, MRI offers notable benefits, including radiation-free imaging and potentially superior resolution and accuracy compared with other imaging techniques. Consequently, the continued advancement of MRI as a noninvasive diagnostic method in dentistry, particularly for assessing pulp condition, holds substantial promise for improving endodontic diagnosis and subsequent treatment decision-making.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"High-Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age\".","authors":"Masaaki Hori, Kei Nakahara, Masahiro Kobayashi","doi":"10.1002/jmri.29745","DOIUrl":"https://doi.org/10.1002/jmri.29745","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-Treatment Breast MRI: Clinical Indications, Outcomes, and Future Directions.","authors":"Brian N Dontchos, Matthew D Phelps, Habib Rahbar, Diana L Lam","doi":"10.1002/jmri.29741","DOIUrl":"https://doi.org/10.1002/jmri.29741","url":null,"abstract":"<p><p>Breast MRI is the most sensitive modality for assessing the extent of disease in patients with newly-diagnosed breast cancer because it identifies clinically- and mammographically-occult breast cancers. Though highly sensitive, breast MRI has lower specificity that may result in false positive findings and potential overestimation of disease if additional MRI findings are not biopsied prior to surgery. It had been anticipated that the superior cancer detection rate of pre-treatment MRI would translate to improved immediate (surgical re-excision) and long-term patient outcomes such as breast cancer recurrence and survival rates, but studies have not necessarily supported this assumption. In this review, current recommendations and utilization of breast MRI for pre-treatment local staging of breast cancer will be presented, with an emphasis on specific clinical scenarios for patient selection and its impact on short- and long-term patient clinical outcomes. We will also present new evidence that pre-treatment MRI may support de-escalation of treatment and discuss emerging advanced MRI techniques that may improve diagnostic performance.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Impact Clinical Applications of Cardiac Magnetic Resonance Imaging in Women: A Review.","authors":"Alex Diaz, Chelsea Meloche, Mohamed Abdelmotleb, Hamid Chalian, Ana Paula Santos Lima, Luba Frank, Karen Ordovas","doi":"10.1002/jmri.29736","DOIUrl":"https://doi.org/10.1002/jmri.29736","url":null,"abstract":"<p><p>The diagnosis of cardiovascular disease in women poses an ongoing challenge due to lack of knowledge about sex differences in the manifestations of cardiovascular disease, since women have been underrepresented in cardiovascular research studies that guide current practice. The purpose of this article is to review a spectrum of cardiovascular disorders which occur exclusively or more frequently in women and to highlight the role that cardiovascular magnetic resonance (MR) plays in diagnosing and prognosticating these disorders. Specifically, this review focuses on cardio-oncologic, ischemic, inflammatory, autoimmune, peri-partum, and genetic manifestations of cardiomyopathy in women. We strive to draw attention to the added diagnostic value provided by cardiac MR, compared against alternative imaging modalities, and propose opportunities for further research on sex differences in imaging and diagnosing cardiovascular diseases. EVIDENCE LEVEL: 1 TECHNICAL EFFICACY: Stage 3.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age.","authors":"Zhiyi Hu, Dengrong Jiang, Jennifer Shepard, Yuto Uchida, Kenichi Oishi, Wen Shi, Peiying Liu, Doris Lin, Vivek Yedavalli, Aylin Tekes, William Christopher Golden, Hanzhang Lu","doi":"10.1002/jmri.29740","DOIUrl":"https://doi.org/10.1002/jmri.29740","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Perfusion imaging of the brain has important clinical applications in detecting neurological abnormalities in neonates. However, such tools have not been available to date. Although arterial-spin-labeling (ASL) MRI is a powerful noninvasive tool to measure perfusion, its application in neonates has encountered obstacles related to low signal-to-noise ratio (SNR), large-vessel contaminations, and lack of technical development studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To systematically develop and optimize ASL perfusion MRI in healthy neonates under 1 week of age.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study type: &lt;/strong&gt;Prospective.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Subjects: &lt;/strong&gt;Thirty-two healthy term neonates (19 female; postnatal age 1.9 ± 0.7 days).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Field strength/sequence: &lt;/strong&gt;3.0 T; T&lt;sub&gt;2&lt;/sub&gt;-weighted half-Fourier single-shot turbo-spin-echo (HASTE) imaging, single-delay and multi-delay 3D gradient-and-spin-echo (GRASE) large-vessel-suppression pseudo-continuous ASL (LVS-pCASL).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Assessment: &lt;/strong&gt;Three studies were conducted. First, an LVS-pCASL MRI sequence was developed to suppress large-vessel spurious signals in neonatal pCASL. Second, multiple post-labeling delays (PLDs) LVS-pCASL were employed to simultaneously estimate normative cerebral blood flow (CBF) and arterial transit time (ATT) in neonates. Third, an enhanced background-suppression (BS) scheme was developed to increase the SNR of neonatal pCASL.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Statistical tests: &lt;/strong&gt;Repeated measure analysis-of-variance, paired t-test, spatial intraclass-correlation-coefficient (ICC), and voxel-wise coefficient-of-variation (CoV). P-value &lt;0.05 was considered significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;LVS-pCASL reduced spurious ASL signals, making the CBF images more homogenous and significantly reducing the temporal variation of CBF measurements by 58.0% when compared to the standard pCASL. Multi-PLD ASL yielded ATT and CBF maps showing a longer ATT and lower CBF in the white matter relative to the gray matter. The highest CBF was observed in basal ganglia and thalamus (10.4 ± 1.9 mL/100 g/min). Enhanced BS resulted in significantly higher test-retest reproducibility (ICC = 0.90 ± 0.04, CoV = 8.4 ± 1.2%) when compared to regular BS (ICC = 0.59 ± 0.12, CoV = 23.6 ± 3.8%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data conclusion: &lt;/strong&gt;We devised an ASL method that can generate whole-brain CBF images in 4 minutes with a test-retest image ICC of 0.9. This technique holds potential for studying neonatal brain diseases involving perfusion abnormalities.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Plain language summary: &lt;/strong&gt;MR imaging of cerebral blood flow in neonates remains a challenge due to low blood flow rates and confounding factors from large blood vessels. This study systematically developed an advanced MRI technique to enhance the reliability of perfusion measurements in neonates. The proposed method reduced signal artifacts from large blood vessels and improved the signal-to-noi","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}