Journal of Magnetic Resonance Imaging最新文献

{"title":"Editorial for \"Prostate Cancer Risk Stratification and Scan Tailoring Using Deep Learning on Abbreviated Prostate MRI\".","authors":"Felipe Sahb Furtado","doi":"10.1002/jmri.29806","DOIUrl":"10.1002/jmri.29806","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"867-868"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Habitat Radiomics Based on Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Assessing Axillary Lymph Node Burden in Clinical T1-T2 Stage Breast Cancer: A Multicenter and Interpretable Study.","authors":"Siyi Chen, Yue Zhang, Yuqi Su, Jie Tian, Yongxin Chen, Wenjie Tang, Yaheng Fan, Chen Jin, Yangcheng He, Yongzhou Xu, Hong Hu, Yuan Guo, Junping Li","doi":"10.1002/jmri.29796","DOIUrl":"10.1002/jmri.29796","url":null,"abstract":"<p><strong>Background: </strong>Axillary lymph node burden(ALNB) is a critical factor in determining treatment strategies for clinical T₁-T₂ (cT₁-T₂) stage breast cancer. However, as ALNB assessment relies on invasive procedures, exploring non-invasive methods is essential.</p><p><strong>Purpose: </strong>To develop and validate a habitat radiomics model for assessing ALNB in cT₁-T₂ breast cancer, incorporating radiogenomic data to improve interpretability.</p><p><strong>Study type: </strong>Retrospective.</p><p><strong>Population: </strong>468 patients with cT₁-T₂ stage breast cancer from two institutions and The Cancer Imaging Archive (TCIA) and The Cancer Genome Atlas (TCGA)-Breast Invasive Carcinoma (BRCA) were included. The cohort was divided into training (n = 173), internal validation (n = 58), external validation (n = 130), and TCGA-BRCA sets (n = 107). Patients were categorized into high nodal burden (HNB; > 3 positive lymph nodes) and non-HNB (≤ 3 positive lymph nodes) groups.</p><p><strong>Field strength/sequence: </strong>1.5-T MRI and 3.0-T MRI, and three-dimensional dynamic contrast-enhanced T1-weighted gradient-echo sequences.</p><p><strong>Assessment: </strong>Two logistic regression models were developed using habitat-based and clinical features. Model performance was evaluated using the AUC. SHapley Additive exPlanations (SHAP) analysis was employed to identify key features. Radiogenomic analysis, including gene set enrichment and drug sensitivity assessments, was conducted using transcriptomic data from the TCGA-BRCA set.</p><p><strong>Statistical tests: </strong>Pearson correlation, Mann-Whitney U, genetic algorithm, logistic regression, AUC analysis, delong test, and SHAP analysis. A p-value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The Habitat model outperformed the Clinical model (AUCs: 0.840-0.932 vs. 0.558-0.673). The SHAP analysis was used to rank feature importance, with subregion 3 showing the highest average SHAP value. Radiogenomic analysis indicated upregulation of the KEGG ribosome pathway in the HNB group and identified differential drug sensitivity profiles among risk groups.</p><p><strong>Data conclusion: </strong>The Habitat model has the potential to assess ALNB in cT₁-T₂ breast cancer and assist radiologists in axillary diagnosis, which may help reduce the need for unnecessary ALN dissection.</p><p><strong>Evidence level: </strong>3. Technical Efficacy: Stage 2.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"751-764"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"MRI Assessment of Lung Water Density in Individuals Previously Infected With COVID-19: A Cross-Sectional Study\".","authors":"Laura C Saunders, A A Roger Thompson, Jim M Wild","doi":"10.1002/jmri.29821","DOIUrl":"10.1002/jmri.29821","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"779-780"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age.","authors":"Zhiyi Hu, Dengrong Jiang, Jennifer Shepard, Yuto Uchida, Kenichi Oishi, Wen Shi, Peiying Liu, Doris Lin, Vivek Yedavalli, Aylin Tekes, William Christopher Golden, Hanzhang Lu","doi":"10.1002/jmri.29740","DOIUrl":"10.1002/jmri.29740","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Perfusion imaging of the brain has important clinical applications in detecting neurological abnormalities in neonates. However, such tools have not been available to date. Although arterial-spin-labeling (ASL) MRI is a powerful noninvasive tool to measure perfusion, its application in neonates has encountered obstacles related to low signal-to-noise ratio (SNR), large-vessel contaminations, and lack of technical development studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To systematically develop and optimize ASL perfusion MRI in healthy neonates under 1 week of age.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study type: &lt;/strong&gt;Prospective.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Subjects: &lt;/strong&gt;Thirty-two healthy term neonates (19 female; postnatal age 1.9 ± 0.7 days).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Field strength/sequence: &lt;/strong&gt;3.0 T; T&lt;sub&gt;2&lt;/sub&gt; -weighted half-Fourier single-shot turbo-spin-echo (HASTE) imaging, single-delay and multi-delay 3D gradient-and-spin-echo (GRASE) large-vessel-suppression pseudo-continuous ASL (LVS-pCASL).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Assessment: &lt;/strong&gt;Three studies were conducted. First, an LVS-pCASL MRI sequence was developed to suppress large-vessel spurious signals in neonatal pCASL. Second, multiple post-labeling delays (PLDs) LVS-pCASL were employed to simultaneously estimate normative cerebral blood flow (CBF) and arterial transit time (ATT) in neonates. Third, an enhanced background-suppression (BS) scheme was developed to increase the SNR of neonatal pCASL.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Statistical tests: &lt;/strong&gt;Repeated measure analysis-of-variance, paired t-test, spatial intraclass-correlation-coefficient (ICC), and voxel-wise coefficient-of-variation (CoV). P-value &lt;0.05 was considered significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;LVS-pCASL reduced spurious ASL signals, making the CBF images more homogenous and significantly reducing the temporal variation of CBF measurements by 58.0% when compared to the standard pCASL. Multi-PLD ASL yielded ATT and CBF maps showing a longer ATT and lower CBF in the white matter relative to the gray matter. The highest CBF was observed in basal ganglia and thalamus (10.4 ± 1.9 mL/100 g/min). Enhanced BS resulted in significantly higher test-retest reproducibility (ICC = 0.90 ± 0.04, CoV = 8.4 ± 1.2%) when compared to regular BS (ICC = 0.59 ± 0.12, CoV = 23.6 ± 3.8%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Data conclusion: &lt;/strong&gt;We devised an ASL method that can generate whole-brain CBF images in 4 minutes with a test-retest image ICC of 0.9. This technique holds potential for studying neonatal brain diseases involving perfusion abnormalities.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Plain language summary: &lt;/strong&gt;MR imaging of cerebral blood flow in neonates remains a challenge due to low blood flow rates and confounding factors from large blood vessels. This study systematically developed an advanced MRI technique to enhance the reliability of perfusion measurements in neonates. The proposed method reduced signal artifacts from large blood vessels and improved the signal-to-no","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"737-748"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12335930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Altered Brain Functional Networks in Patients With Breast Cancer After Different Cycles of Neoadjuvant Chemotherapy\".","authors":"Hernan Jara, Chad W Farris","doi":"10.1002/jmri.29773","DOIUrl":"10.1002/jmri.29773","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"915-916"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Improved and Automated Detection of Papillary Muscle Infarction Using Joint Bright- and Black-Blood Late Gadolinium Enhancement MRI\".","authors":"Robert J Holtackers, Akos Varga-Szemes, Martijn W Smulders","doi":"10.1002/jmri.29794","DOIUrl":"10.1002/jmri.29794","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":"840-841"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Specific Cardiac Magnetic Resonance Phenotypes in Danon Disease: A Retrospective Cohort Study.","authors":"Ni Liu, Kai Yang, Guijuan Cao, Zixian Chen, Gang Yin, Wenhao Dong, Xiang Wang, Jinghui Li, Minjie Lu","doi":"10.1002/jmri.70102","DOIUrl":"https://doi.org/10.1002/jmri.70102","url":null,"abstract":"<p><strong>Background: </strong>Danon disease (DD), an X-linked disorder due to lysosome-associated membrane protein 2 (LAMP2) mutations, features life-threatening cardiomyopathy. Sex-based cardiac magnetic resonance (cardiac MR) differences are recognized but lack quantitative analysis despite their critical importance in establishing sex-specific diagnostic thresholds and personalized treatment strategies.</p><p><strong>Purpose: </strong>To investigate sex-based differences in cardiac MR manifestations in DD.</p><p><strong>Study type: </strong>Retrospective.</p><p><strong>Subjects: </strong>24 DD patients (15 males, 9 females; January 2018-February 2025).</p><p><strong>Field strength/sequence: </strong>3-T, cine imaging (gradient-echo sequence), late gadolinium enhancement (LGE) imaging (inversion-recovery gradient-echo sequence), T1 mapping (modified look-locker inversion-recovery gradient-echo sequence), T2 mapping (gradient-echo sequence with T2 preparation).</p><p><strong>Assessment: </strong>Standardized cardiac MR assessed structural indices (LV volumes/mass, wall thickness), functional metrics (EF, strain), and tissue characterization (late gadolinium enhancement [LGE extent, T1/T2 values]).</p><p><strong>Statistical tests: </strong>Sex comparisons used independent t-tests/Mann-Whitney U for continuous variables; Chi-square/Fisher's exact for categorical variables. p < 0.05 significant.</p><p><strong>Results: </strong>Males predominantly developed hypertrophic cardiomyopathy (HCM: 73.3%), whereas females universally exhibited dilated cardiomyopathy (DCM: 88.9%) with preserved septal thickness. Ventricular arrhythmias occurred in all females (100% vs. 73.3% in males). Females showed significantly worse left ventricular ejection fraction (LVEF: 37.0% ± 14.0% vs. 49.9% ± 17.9%). Cardiac MR revealed extensive LGE (21.9% ± 11.4%, diffuse free-wall involvement), elevated extracellular volume (ECV) (ECV: 38% ± 12%), and significantly prolonged T1/T2 values (1374 ± 60 ms/46.5 ± 5.4 ms; T1 was higher in females). Global longitudinal strain (GLS: -6.5% ± 4.0%), radial strain (GRS: 16.9% ± 12.2%), and circumferential strain (GCS: -10.6% ± 5.7%) were reduced, with significantly worse systolic impairment in females.</p><p><strong>Data conclusion: </strong>Sex-specific cardiac MR patterns exist in DD: males predominantly develop HCM, whereas females primarily exhibit DCM, with apical/free wall LGE observed in both sexes, though mid-basal septum sparing is more frequent in males. These findings enable sex-stratified early diagnosis and phenotype-tailored surveillance, guiding clinical management.</p><p><strong>Evidence level: </strong>4.</p><p><strong>Technical efficacy: </strong>Stage 2.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Meta-Analysis Informed Functional Connectomes Representations for Depression Identification\".","authors":"Li Wang, Jiliang Fang, Tianyi Yan","doi":"10.1002/jmri.70106","DOIUrl":"https://doi.org/10.1002/jmri.70106","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Associations Between Hippocampal Transverse Relaxation Time and Amyloid PET in Cognitively Normal Aging Adults\".","authors":"Nicolau Beckmann","doi":"10.1002/jmri.70104","DOIUrl":"https://doi.org/10.1002/jmri.70104","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Age-, Body Surface Area-, and Sex-Specific Reference Values for Pericardial Adipose Tissue in Children: An MRI Study\".","authors":"Marcelo F Kozak","doi":"10.1002/jmri.70062","DOIUrl":"https://doi.org/10.1002/jmri.70062","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}