Journal of Magnetic Resonance Imaging最新文献_第4页

Morphological Study on Lenticulostriate Arteries in Patients With Middle Cerebral Artery Stenosis at 7 T MRI. 大脑中动脉狭窄患者皮状纹状动脉的7t MRI形态学研究。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-09 DOI: 10.1002/jmri.29693

Runze Li, Jinhao Lyu, Rui Hu, Qi Duan, Wanbing Wang, Xiangbing Bian, Caohui Duan, Song Wang, Xiaolin Guo, Aoxue Mei, Xin Lou

{"title":"Morphological Study on Lenticulostriate Arteries in Patients With Middle Cerebral Artery Stenosis at 7 T MRI.","authors":"Runze Li, Jinhao Lyu, Rui Hu, Qi Duan, Wanbing Wang, Xiangbing Bian, Caohui Duan, Song Wang, Xiaolin Guo, Aoxue Mei, Xin Lou","doi":"10.1002/jmri.29693","DOIUrl":"https://doi.org/10.1002/jmri.29693","url":null,"abstract":"Background: Middle cerebral artery (MCA) stenosis affects lenticulostriate arteries (LSAs) that supply the basal ganglia. Increased spatial resolution and signal-to-noise ratio of 7 T could facilitate morphological imaging of very-small-diameter LSAs.Purpose: To evaluate differences in morphological characteristics of LSA among different MCA stenoses.Study type: Prospective.Subjects: We enrolled 161 patients (age: 26-83 years, 115 males) with MCA-M1-segment stenosis, and assigned them to the symptomatic (ischemic stroke on imaging, or transient ischemic attack diagnosed clinically within 90 days) and asymptomatic (mild-to-moderate stenosis, ≤70% diameter reduction and severe stenosis, >70% and ≤99% diameter reductions) groups and further subdivided them into the proximal and distal stenosis subgroups.Field strength/sequence: 7 T, three-dimensional time-of-flight magnetic resonance angiography (3D TOF-MRA).Assessment: The number of LSA stems, branches, length, and tortuosity (LSA length/linear distance between LSA start- and endpoints) were evaluated independently in both hemispheres by 3 radiologists with 2-, 10-, and 12-years' experience, and inter-group and inter-subgroup comparisons were undertaken.Statistical tests: Independent t tests, paired t tests, chi-square test, and multiple linear regression analysis (P < 0.05 indicated statistical significance).Results: Compared with the asymptomatic group (N = 76), the symptomatic group (N = 85) had significantly fewer LSA branches (7.58 ± 2.31 vs. 9.29 ± 2.37) and shorter length (4.32 ± 0.84 vs. 4.59 ± 0.72 cm). There were no significant intergroup differences in LSA morphological characteristics between the mild-to-moderate and severe-stenosis subgroups (LSA stems: P = 0.457, LSA branches: P = 0.433, LSA length: P = 0.150, and LSA tortuosity: P = 0.613). The proximal stenosis subgroup had significantly fewer (8.08 ± 1.80 vs. 10.64 ± 2.21) and shorter LSA branches (4.43 ± 0.69 vs. 4.76 ± 0.71 cm) than in the distal stenosis subgroup. Multiple linear regression, after false discovery rate correction, showed that symptoms and the MCA-M1-segment-stenosis site (proximal/distal) were significantly associated with LSA and length.Data conclusion: Having symptoms and a proximal MCA-M1 segment stenosis were associated with fewer LSA branches, whereas stenosis severity did not significantly affect LSA morphological characteristics.Plain language summary: Lenticulostriate arteries mainly originate from the middle cerebral artery, which 7 T magnetic resonance imaging (MRI) can help visualize effectively. We mainly focused on evaluating lenticulostriate artery stems, branches, length, and tortuosity (length/linear distance between start- and endpoints) among 3 types of middle cer","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Luminal and Hemodynamic Evaluation of the Cervical Arteries Using Nonenhanced 3D Quantitative Quiescent-Interval Slice-Selective Magnetic Resonance Angiography. 使用非增强的三维定量静止间隔切片选择磁共振血管造影同时评价颈动脉的腔室和血流动力学。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-09 DOI: 10.1002/jmri.29701

Ioannis Koktzoglou, Onural Ozturk, William J Ankenbrandt, Matthew T Walker, Zachary B Bulwa, Fulvio R Gil, William J Ares, Nondas Leloudas, Robert R Edelman

{"title":"Simultaneous Luminal and Hemodynamic Evaluation of the Cervical Arteries Using Nonenhanced 3D Quantitative Quiescent-Interval Slice-Selective Magnetic Resonance Angiography.","authors":"Ioannis Koktzoglou, Onural Ozturk, William J Ankenbrandt, Matthew T Walker, Zachary B Bulwa, Fulvio R Gil, William J Ares, Nondas Leloudas, Robert R Edelman","doi":"10.1002/jmri.29701","DOIUrl":"https://doi.org/10.1002/jmri.29701","url":null,"abstract":"Background: Luminal and hemodynamic evaluations of the cervical arteries inform the diagnosis and management of patients with cervical arterial disease.Purpose: To demonstrate a 3D nonenhanced quantitative quiescent interval slice-selective (qQISS) magnetic resonance angiographic (MRA) strategy that provides simultaneous hemodynamic and luminal evaluation of the cervical arteries.Study type: Prospective.Subjects: Six healthy volunteers (3 female, 3 male, age = 35.7 ± 10.3 years) and 14 patients with cerebrovascular disease (12 female, 2 male, age = 56.6 ± 14.0 years).Field strength/sequences: 3 T, ungated 3D tilted-slab qQISS, pulse-gated 2D phase contrast (PC), ungated 3D PC, and 3D time-of-flight (TOF) gradient-echo protocols.Assessment: Four readers scored 29 arterial segments on 3D qQISS volumes for image quality using a 4-point scale (1: non-diagnostic, 2: fair, 3: good, 4: excellent). Time-averaged arterial flow velocities and volume flow rates obtained with qQISS and PC protocols were compared. Arterial lumen area and radius measures obtained with 3D protocols were compared in a subgroup.Statistical tests: Gwet's AC2; intraclass correlation coefficient (ICC); Pearson's correlation; Bland-Altman. P values <0.05 were considered statistically significant.Results: 3D qQISS provided good-to-excellent image quality for depicting the cervical arteries (mean scores of 3.72 ± 0.55, 3.55 ± 0.66, 3.42 ± 0.72, and 3.66 ± 0.73 for readers 1, 2, 3, and 4) with significant inter-reader agreement (AC2 = 0.91, ICC = 0.53) in image scoring, significantly agreed with pulse-gated 2D PC for time-averaged total flow velocity (ICC = 0.83) and volume flow rate (ICC = 0.92), and significantly agreed with 3D PC for total flow velocity (ICC = 0.70), volume flow rate (ICC = 0.91), and component flow velocity (ICC = 0.89). Compared with 3D PC, 3D qQISS better agreed with 3D TOF for arterial lumen area (ICC = 0.97 vs. 0.72) and radius (ICC = 0.94 vs. 0.74).Data conclusion: Nonenhanced 3D qQISS provides high-quality sub-1 mm3 spatial resolution imaging of the cervical arteries, excellent agreement of arterial structural measures with respect to 3D TOF, and time-averaged hemodynamic data without the need for additional PC imaging.Plain language summary: Magnetic resonance angiography (MRA), a method for depicting blood vessels within the body, can be used to evaluate arterial diseases and disorders of the neck. MRA methods routinely used to evaluate the neck arteries do not measure blood flow speed and volume, while other methods for obtaining this information provide less accurate pictures of arterial structure and are not routinely collected. This article reports a new method for MRA that clearly and efficiently portrays the n","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Moderate to High Static Magnetic Fields on Pancreatic Damage. 中高静磁场对胰腺损伤的影响。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-09 DOI: 10.1002/jmri.29704

Ying Wang, Weili Chen, Junjun Wang, Chao Song, Lei Zhang, Xin Zhang

{"title":"The Effects of Moderate to High Static Magnetic Fields on Pancreatic Damage.","authors":"Ying Wang, Weili Chen, Junjun Wang, Chao Song, Lei Zhang, Xin Zhang","doi":"10.1002/jmri.29704","DOIUrl":"https://doi.org/10.1002/jmri.29704","url":null,"abstract":"Background: Pancreatic damage is a common digestive system disease with no specific drugs. Static magnetic field (SMF), the key component of magnetic resonance imaging (MRI), has demonstrated prominent effects in various disease models.Purpose: To study the effects of 0.1-9.4 T SMFs on pancreatic injury induced by alcohol, and acute pancreatitis (AP) induced by L-arginine (L-Arg).Study type: Prospective, animal model.Animal model: Twelve healthy C57BL/6J male mice, 30 AP model male mice, and 30 alcohol-associated liver disease (AALD) model male mice.Field strength/sequence: 1.5-9.4 T SMFs for 12 hours and 0.1 T SMF for 72 hours. No imaging sequence was used.Assessment: Histological analysis on AALD mice pancreas was conducted. For L-Arg-induced AP mice, their body weight, food/water consumption, open field behavior, blood analysis, as well as histological analysis, inflammatory, oxidative stress of the pancreas were measured. In vitro cellular experiments were also conducted.Statistical tests: Data are presented as means ± SD and analyzed using the two-tailed Student's t-test or one-way analysis of variance (ANOVA) test. P values <0.05 were considered statistically significant.Results: 1.5-7 T SMFs significantly reduced alcohol-induced pancreatic damage, increasing the structurally intact acinar area from 51.5% to 78.3%, whereas the effect of 9.4 T SMF is not obvious. 0.1 T SMF can reduce the AP mice lethality, increase the structurally intact acinar area from 31.0% to 59.7%, associated with the reduced pancreatic inflammatory responses (78.1% reduction of F4/80 and 80.0% reduction of MPO), 20.0% decreased oxidative stress and 53.2% reduced pancreatic cell apoptosis.Data conclusion: High-field MRI may be safe for pancreatic-related diseases at the animal level. SMFs have a future potential to be developed as non-invasive and highly penetrating physical modalities for the treatment of pancreatic injury including AP.Plain language summary: This study aims to evaluate the safety and potential therapeutic effects of moderate- to high-intensity static magnetic fields (SMFs) on mice with pancreatic injury. Their findings revealed that SMFs between 1.5 and 7 Tesla (T) helped reduce alcohol-induced pancreatic damage, while a stronger 9.4 T showed no effect. Interestingly, for mice with L-arginine-induced acute pancreatitis, a weaker 0.1 T significantly increased the area of healthy acinar cells from 31.0% to 59.7%. These results not only suggest that MRI-related SMFs are safe for pancreatic diseases in animals, but also unravel the potential of SMFs as a future treatment option for pancreatic disorders.Evidence level: N/A TECHNICAL EFFICACY: Stage 1.","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial for "MRI Signs Associated With Bladder Injury During Cesarean Delivery in Severe Placenta Accreta Spectrum Disorders". 《严重胎盘增生谱系障碍剖宫产时膀胱损伤的MRI征象》的社论。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-09 DOI: 10.1002/jmri.29714

Evgenia Efthymiou, Nikolaos L Kelekis

引用次数: 0

Editorial for "Development and Validation of a Deep Learning System to Differentiate HER2-Zero, HER2-Low, and HER2-Positive Breast Cancer Based on Dynamic Contrast-Enhanced MRI". 为“基于动态增强MRI区分her2 - 0、HER2-Low和her2 -阳性乳腺癌的深度学习系统的开发和验证”撰写的社论。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-08 DOI: 10.1002/jmri.29697

Glen R Morrell

引用次数: 0

Exercise MR of Skeletal Muscles, the Heart, and the Brain

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-07 DOI: 10.1002/jmri.29705

Melissa T. Hooijmans PhD, Jeroen A.L. Jeneson PhD, Harald T. Jørstad MD, PhD, Adrianus J. Bakermans PhD

引用次数: 0

Editorial for "Evaluation of Neurovascular Coupling in Early-Onset and Late-Onset Epilepsy of Unknown Etiology". “不明病因早发性和晚发性癫痫的神经血管耦合评价”社论。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2025-01-03 DOI: 10.1002/jmri.29683

Thomas Welton, Yee Leng Tan, Ling-Ling Chan

引用次数: 0

Ventricular Discordance as an MRI Phenotype Provides Prognostic Value Among Arrhythmogenic Cardiomyopathy. 室性不和谐作为一种MRI表型在心律失常性心肌病中提供预后价值。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2024-12-30 DOI: 10.1002/jmri.29699

Jin-Yi Xiang, Yun Zhao, Wei-Hui Xie, Dong-Aolei An, Bing-Hua Chen, Rui Wu, Chong-Wen Wu, Ruo-Yang Shi, Yan Zhou, Lei Zhao, Min-Jie Lu, Lian-Ming Wu

{"title":"Ventricular Discordance as an MRI Phenotype Provides Prognostic Value Among Arrhythmogenic Cardiomyopathy.","authors":"Jin-Yi Xiang, Yun Zhao, Wei-Hui Xie, Dong-Aolei An, Bing-Hua Chen, Rui Wu, Chong-Wen Wu, Ruo-Yang Shi, Yan Zhou, Lei Zhao, Min-Jie Lu, Lian-Ming Wu","doi":"10.1002/jmri.29699","DOIUrl":"https://doi.org/10.1002/jmri.29699","url":null,"abstract":"Background: In arrhythmogenic cardiomyopathy (ACM), left ventricle-dominant presentation has poorer outcomes than right-dominant presentation, suggesting that interventricular functional disparity might play a role in patients' prognosis. However, the prognostic impact of ventricular functional discordance in ACM patients remains unknown.Purpose: To assess whether ventricular functional disparity measured as ventricular discordance index, defined as the ratio of right-ventricular ejection fraction (RVEF) to left-ventricular ejection fraction (LVEF), might reveal prognostic disparities between phenotypes and offer added risk stratification value.Study type: Retrospective.Subjects: A total of 222 patients with ACM (mean age 44 ± 16 years, 144 males) from three centers were included.Field strength/sequence: 3-T, cine imaging.Assessment: Ventricular discordance index was calculated using cine-derived RVEF and LVEF, for which a threshold was determined using Youden J index. Clinically ventricular discordance was defined as ventricular discordance index above the threshold. The major adverse cardiac events (MACE), was defined as sudden cardiac death, appropriate implantable cardioverter-defibrillator intervention, and aborted cardiac arrest. International task diagnostic force criteria and the 5-year risk score were evaluated.Statistical tests: The prognostic implications of ventricular discordance index and clinically ventricular discordance were evaluated using multivariable Cox analysis. P < 0.05 indicated the statistical significance.Results: During a median follow-up of 50 months, 81 (37%) patients experienced MACE. The ventricular discordance index was independently associated with MACE (hazard ratio [HR]: 1.49; 95% confidence interval [CI]: 1.23-1.82). Patients classified under clinically ventricular discordance experienced higher MACE rates and were less likely to meet the task force structural criteria. clinically ventricular discordance was independently associated with MACE (adjusted HR: 2.2; 95% CI: 1.36-3.55). Clinically ventricular discordance, LV involvement and the 5-year risk score in combined reclassified 20.3% of patients compared to 2015 task force classification.Data conclusion: Ventricular discordance was associated with MACE in ACM, potentially providing prognostic value beyond the 5-year risk score.Level of evidence: 3 TECHNICAL EFFICACY: 5.","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial for "Simultaneous Bilateral T₁, T₂, and T_1ρ Relaxation Mapping of Hip Joint With 3D-MRI Fingerprinting". 社论“同时双侧T1， T2和T1ρ松弛髋关节与3D-MRI指纹图谱”。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2024-12-30 DOI: 10.1002/jmri.29685

Cory R Wyatt

引用次数: 0

T₂ Clusters Are More Sensitive Than Mean T₂ Change to Detect Early and Longitudinal Changes in Anterior Cruciate Ligament Reconstructed and Healthy Knees. T2簇对前交叉韧带重建及健康膝关节早期和纵向变化的检测比平均T2变化更敏感。

IF 3.3 2区医学

Journal of Magnetic Resonance Imaging Pub Date : 2024-12-30 DOI: 10.1002/jmri.29689

Anoosha Pai S, Anthony A Gatti, Marianne S Black, Katherine A Young, Arjun D Desai, Marco Barbieri, Jessica L Asay, Seth L Sherman, Garry E Gold, Feliks Kogan, Brian A Hargreaves, Akshay S Chaudhari

{"title":"T2 Clusters Are More Sensitive Than Mean T2 Change to Detect Early and Longitudinal Changes in Anterior Cruciate Ligament Reconstructed and Healthy Knees.","authors":"Anoosha Pai S, Anthony A Gatti, Marianne S Black, Katherine A Young, Arjun D Desai, Marco Barbieri, Jessica L Asay, Seth L Sherman, Garry E Gold, Feliks Kogan, Brian A Hargreaves, Akshay S Chaudhari","doi":"10.1002/jmri.29689","DOIUrl":"https://doi.org/10.1002/jmri.29689","url":null,"abstract":"Background: Post-traumatic osteoarthritis (PTOA) often follows anterior cruciate ligament reconstruction (ACLR), leading to early cartilage degradation. Change in mean T2 fails to capture subject-specific spatial-temporal variations, highlighting the need for robust quantitative methods for early PTOA detection and monitoring.Purpose/hypothesis: Develop and apply 3D T2 cluster analysis to ACLR and healthy knees over 2.5 years.Study type: Longitudinal case-control study.Subjects: ACLR and contralateral knees of 15 subjects (9 male/6 female, 37.7 ± 10 years) and right knee of 15 matched controls (9 male/6 female, 37.1 ± 12 years) were scanned at 3 weeks, 3, 9, 18, and 30 months post-ACLR.Sequence: 3 T Quantitative double echo steady state sequence.Assessment: \"T2 cluster analysis\" was developed, incorporating registration and thresholding methods to identify and quantify elevated T2 regions (T2 clusters, T2C) in femoral cartilage. Percentage of cartilage covered by T2 clusters (T2C%), mean cluster size (T2Csize), the number of clusters (T2Ccount), and ΔT2Mean (change in mean femoral cartilage T2 relative to visit 1) were computed for all knees.Statistical tests: A linear mixed model assessed knee, time, and knee-time interaction effects on each outcome metric (P < 0.05), with effect sizes (ηp 2) describing the sensitivity of these effects to longitudinal changes.Results: T2C% (ηp 2 = 0.22), T2Csize, (ηp 2 = 0.14), and T2Ccount (ηp 2 = 0.51) showed significant and systematic difference between knees (ACLR > contralateral > control). T2C% (ηp 2 = 0.24), T2Csize (ηp 2 = 0.17), and T2Ccount (ηp 2 = 0.11) showed significant longitudinal change across all knees. Specifically, ACLR knees exhibited a significant increase in T2C% (ηp 2 = 0.21), T2Csize (ηp 2 = 0.13), and a decrease in T2Ccount (ηp 2 = 0.07) with time. ΔT2Mean showed significant difference between knees (ηp 2 = 0.15), increase with time (ηp 2 = 0.04), with no significant knee-time interaction (ηp 2 = 0.00, P = 0.772 [contralateral], P = 0.482 [control]).Conclusion: T2C metrics are more sensitive than ΔT2Mean for lo","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0