Journal of Magnetic Resonance Imaging最新文献

{"title":"Assessing the Impact of Imaging Parameters on MRI Measurement of Kidney T₂.","authors":"Alexander J Daniel, Susan T Francis","doi":"10.1002/jmri.70127","DOIUrl":"https://doi.org/10.1002/jmri.70127","url":null,"abstract":"<p><strong>Background: </strong>T₂-mapping has promise to evaluate kidney pathophysiology. Prior studies show a large variance in kidney T₂, likely due to the differing acquisition sequences.</p><p><strong>Purpose: </strong>To compare four T₂-mapping sequences to investigate kidney T₂.</p><p><strong>Study type: </strong>Phantom and prospective in vivo assessments.</p><p><strong>Participants: </strong>ISMRM/NIST and QASPER phantoms; 8 healthy volunteers (4 female, 30 ± 8 years).</p><p><strong>Field strength/sequence: </strong>3 T, spin echo-echo planar imaging (SE-EPI), multi-echo-spin echo (ME-SE), Gradient and Spin Echo (GraSE) vendor-provided sequences, and custom T₂-prepared EPI, Dual-echo B₀-mapping and DREAM B₁-mapping.</p><p><strong>Assessment: </strong>T₂-mapping accuracy in the ISMRM/NIST phantom in the presence of B₀ frequency offset and B₁ ⁺ by scaling of flip angles, and in the QASPER phantom in the presence of diffusion by altering pump rate compared to being turned off. Participants underwent a single 45-min exam to collect four T₂-mapping sequences, B₀ and B₁ maps. In vivo T₂ values compared across sequences and the influence of B₀ and B₁ ⁺ was evaluated.</p><p><strong>Statistical tests: </strong>Shapiro-Wilk, Wilcoxon signed-rank, Student's t-test, Coefficient of Variation, Pearson's correlation coefficient, linear mixed effect model. p < 0.05 considered statistically significant.</p><p><strong>Results: </strong>SE-EPI, ME-SE, GraSE, and T₂-prepared EPI had a mean absolute scaled error of 0.52, 0.52, 0.36, and 0.27 over the kidney T₂ range of the ISMRM/NIST phantom. GraSE was most robust to perturbations in B₀/B₁ ⁺. In the QASPER phantom, SE-EPI was highly sensitive to diffusion leading to T₂ shortening (66%), while multi-echo sequences had lower diffusion sensitivity ordered by shortest echo spacing (ME-SE 81%, T₂-prepared EPI 90%, GraSE 95% reduction in T₂). In vivo, SE-EPI measured T₂ was significantly lower than multi-echo sequences, and SE-EPI and T₂-preparation had a -0.52 ± 0.08 and -0.57 ± 0.06 ms/% dependence on B₁ ⁺.</p><p><strong>Data conclusion: </strong>To reduce B₀, B₁ ⁺, and diffusion sensitivity for kidney T₂-mapping, a multi-echo sequence spanning echo times up to the kidney T₂ (~140 ms at 3 T) is recommended. Collecting data with different echo spacings can isolate the diffusion-related T₂ component.</p><p><strong>Evidence level: </strong>2.</p><p><strong>Technical efficacy: </strong>Stage 1.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"T2-Weighted Imaging and Intravoxel Incoherent Motion for Monitoring Glomerulonephritis.","authors":"Jian Liu, Yu Wu, Daoyu Yang, Xunlan Zhang, Rui Lv, Rongpin Wang, Xianchun Zeng","doi":"10.1002/jmri.70125","DOIUrl":"https://doi.org/10.1002/jmri.70125","url":null,"abstract":"<p><strong>Background: </strong>Lack of reliable noninvasive diagnostic tools limits timely management of glomerulonephritis (GN), a major cause of chronic kidney disease.</p><p><strong>Purpose: </strong>To validate the performance of intravoxel incoherent motion (IVIM) imaging and T2-weighted imaging (T2WI) in monitoring renal injury in rats with GN.</p><p><strong>Study type: </strong>Prospective, animal model.</p><p><strong>Subjects: </strong>Eighty-one Sprague-Dawley rats (54 GN, 27 control) underwent renal MRI at nine time points from Day 2 to Week 16 (GN: n = 6; control: n = 3 per time point).</p><p><strong>Field strength/sequence: </strong>3.0T; IVIM and T2WI.</p><p><strong>Assessment: </strong>IVIM parameters (D, D*, f) and standardized signal intensities (SSI) on T2WI were calculated for renal cortex and outer medulla and correlated with histology.</p><p><strong>Statistical tests: </strong>One-way analysis of variance was used for longitudinal changes and independent t-test for comparing GN and controls at each time point. Receiver operating characteristic (ROC) curve analysis assessed diagnostic performance for identifying GN.</p><p><strong>Results: </strong>Cortex, outer stripe of outer medulla (OM) and inner stripe of the outer medulla (IM) showed early SSI increase followed by gradual decline. SSI of OM was significantly higher than controls at Days 5 (2.19 ± 0.76), 10 (2.99 ± 0.34), 15 (2.46 ± 0.37), and Week 4 (2.23 ± 0.66). In GN rats, D progressively declined from Day 2 to Week 16: from 1.51 ± 0.40 to 0.91 ± 0.45 (×10^-3 mm²/s) in cortex, and from 1.37 ± 0.23 to 0.62 ± 0.19 (×10^-3 mm²/s) in outer medulla. D* and f also decreased progressively in cortex and outer medulla. Significant inverse relationships were observed between IVIM parameters and serum biomarkers (r = -0.39 to -0.80). For diagnostic performance to identify GN, D achieved the highest area under the ROC curves in the cortex (0.926, 95% CI: 0.883-0.970) and outer medulla (0.975, 95% CI: 0.953-0.997).</p><p><strong>Data conclusion: </strong>T2WI reveals early signal changes in GN. IVIM parameters track disease progression, correlate with serum biomarkers, and distinguish GN from healthy controls.</p><p><strong>Level of evidence: 2: </strong></p><p><strong>Technical efficacy: </strong>Stage 1.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Normal Reference Values and Determinants of Right Heart Strain Derived From MR Feature Tracking: A Meta-Analysis\".","authors":"Alexander Schulz, Reza Nezafat","doi":"10.1002/jmri.70124","DOIUrl":"https://doi.org/10.1002/jmri.70124","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of 4D Flow MRI-Derived Pulmonary Regurgitant Fraction in Repaired Tetralogy of Fallot: Impact of Measurement Location and Pulmonary Artery Geometry.","authors":"Hirozumi Mori, Michinobu Nagao, Tomohito Kogure, Seiji Asagai, Kei Inai, Akihiro Inoue, Atsushi Yamamoto, Shuji Sakai, Masahiro Jinzaki","doi":"10.1002/jmri.70131","DOIUrl":"https://doi.org/10.1002/jmri.70131","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary regurgitant fraction (RF) in patients with repaired tetralogy of Fallot (rTOF) is an important indicator for therapeutic intervention. However, the impact of pulmonary artery geometry and turbulent flow on measurement accuracy is unclear.</p><p><strong>Purpose: </strong>To evaluate the reliability of 4D flow MRI-derived and 2D phase contrast (2D-PC) RF assessments, identify clinically useful measurement locations, and investigate factors contributing to variability.</p><p><strong>Study type: </strong>Retrospective.</p><p><strong>Population/subjects: </strong>Thirty-four rTOF patients (21 female; age 45.2 ± 14.4 years).</p><p><strong>Field strength/sequence: </strong>3.0 T; balanced steady-state free precession (bSSFP) cine, time-resolved 2D-PC segmented gradient echo (2D-PC), and time-resolved velocity-sensitized 3D gradient echo with echo planar imaging readout (4D flow) sequences.</p><p><strong>Assessment: </strong>MRI was performed before and 3 months after transcatheter pulmonary valve replacement (TPVI). Indexed right ventricular end-diastolic volume (RVEDVi) was assessed in pre/post bSSFP cine data to evaluate RV remodeling. MPA backward and forward flow volumes (BFV, FFV) and RF were measured using 2D-PC and 4D flow. Six equidistant 4D flow planes from the right ventricular outflow tract to the distal MPA were analyzed, with one additional plane matched to the 2D-PC location. MPA and vortex areas were also assessed for each 4D flow plane.</p><p><strong>Statistical tests: </strong>Spearman's rho assessed correlations between 2D-PC and 4D flow parameters, and area under the receiver operating characteristic curve (AUC) assessed the association between RF and the pre/post TVPI percentage change in RVEDVi.</p><p><strong>Significance: </strong>p < 0.05.</p><p><strong>Results: </strong>2D-PC and 4D flow measurements at the matched MPA plane correlated significantly (RF: ρ = 0.65, FFV: ρ = 0.76, BFV: ρ = 0.87). RF varied by plane, and the plane 10 mm distal to the valve best associated with RVEDVi reduction after TPVI (AUC = 0.84). Changes in FFV between planes significantly correlated with dilatation and stenosis (ρ = 0.432, -0.618), whereas BFV correlated with dilatation alone (ρ = 0.581); however, vortex area enlargement showed no significant association with flow volume changes.</p><p><strong>Data conclusion: </strong>2D-PC and 4D flow measurements show high correlations, but 4D flow accuracy depends on plane location and geometry.</p><p><strong>Evidence level: </strong>3.</p><p><strong>Technical efficacy: </strong>Stage 2.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI Safety Considerations for Permanent Magnet Implants in Muscle.","authors":"Cameron R Taylor, Eric D Anttila, Steven J Charlebois, David C Gross, Amanda F Taylor, Jose O Negron-Garcia, Christopher E Suckow, L Tiffany Lyle, Scott R Hooten, Seong Ho Yeon, Christopher C Shallal, Hugh M Herr","doi":"10.1002/jmri.70126","DOIUrl":"https://doi.org/10.1002/jmri.70126","url":null,"abstract":"<p><strong>Background: </strong>Permanent magnet implants are used with several medical and assistive devices, such as cochlear implants, dental attachments, and prosthetic control, but raise caution for MR imaging. Previous work has evaluated several magnet implants for position and magnetization stability, as well as for image artifacts under MRI. Yet, the intramuscular magnets used for prosthetic control still require evaluation for potential MRI conditionality.</p><p><strong>Purpose: </strong>To investigate the position and magnetization stability of and image artifacts from 3-mm-diameter spherical permanent magnets (B_r = 1.393 T, H_ci = 1.637 MA/m) implanted within muscle.</p><p><strong>Study type: </strong>Prospective longitudinal study.</p><p><strong>Animal model: </strong>Porcine; one animal, eight muscles.</p><p><strong>Field strength/sequence: </strong>0.55-T, 1.5-T/SE, GRE.</p><p><strong>Assessment: </strong>Permanent magnets and nonmagnetic controls were implanted into eight muscles and exposed to 1.5-T MRI 36 days post-implantation. All sites were examined histologically for evidence of implant migration (acute fibrotic response or fibrotic capsule disruption). Benchtop studies evaluated worst-case demagnetization and image artifacts (artifact radius minus implant radius). The primary measure of position stability was histological examination interpreting characteristics of progressive skeletal muscle healing. Secondary position stability analysis was performed via CT imaging.</p><p><strong>Statistical tests: </strong>Unpaired one-sided sign test with a significance level of 0.05. Demagnetization and imaging artifacts were summarized as maximums.</p><p><strong>Results: </strong>Fibrotic capsules were similarly intact at permanent magnet and control sites (fibrotic capsule thicknesses: 20-550 μm [magnets], 20-220 μm [controls]). No effect of MRI exposure on implant migration was observed via secondary analysis (p = 0.965 [0.55-T], p = 0.996 [1.5-T]). Maximum demagnetization was 2.1% under 0.55-T exposure and 13.5% under 1.5-T exposure, and maximum image artifact was 71 mm at both imaging strengths.</p><p><strong>Data conclusion: </strong>The permanent magnet implants used in this study were resistant to migration and substantial demagnetization under 0.55-T and 1.5-T MRI exposure and resulted in negligible image artifacts for critical organ imaging, suggesting that the presence of these implants does not preclude a patient from receiving MR imaging up to 1.5T.</p><p><strong>Evidence level: </strong>N/A.</p><p><strong>Technical efficacy: </strong>Stage 5: Improvements in patient care.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Field Strength, Sex, and Age on Pseudo-Continuous Arterial Spin Labeling and T1 Mapping in the Kidney","authors":"Leyre Garcia-Ruiz,&nbsp;Rebeca Echeverria-Chasco,&nbsp;Verónica Aramendía-Vidaurreta,&nbsp;Sergio M. Solis-Barquero,&nbsp;Nuria Garcia-Fernandez,&nbsp;José María Mora-Gutiérrez,&nbsp;Marta Vidorreta,&nbsp;Gorka Bastarrika,&nbsp;Maria A. Fernández-Seara","doi":"10.1002/jmri.70108","DOIUrl":"https://doi.org/10.1002/jmri.70108","url":null,"abstract":"<p>Quantitative maps obtained in two representative participants in the younger (age = 26 years, male) and older (age = 58 years, male) groups, at Visit 1 for both field strengths (1.5 T and 3 T). The images arranged from left to right include: Perfusion weighted images (pixel values are PWS in %) for six post-labeling delays (PLDs = 0.4, 0.7, 1, 1.3, 1.6, and 1.9 s); renal blood flow (RBF) map (mL/min/100 g) calculated using the single-delay data for the PLD of 1.3 s; RBF (mL/min/100 g) and arterial transit time (ATT) maps (s) calculated using the multi-delay data; and <i>T</i>₁ map (ms). By Garcia-Ruiz et al. (1180–1195)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":"62 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmri.70108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145057759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Preoperative Assessment of Extraprostatic Extension in Prostate Cancer Using an Interpretable Tabular Prior-Data Fitted Network-Based Radiomics Model From MRI\".","authors":"Karthik M Sundaram, Hersh Sagreiya, Mark A Rosen","doi":"10.1002/jmri.70115","DOIUrl":"https://doi.org/10.1002/jmri.70115","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Reference Values and Determinants of Right Heart Strain Derived From MR-Feature Tracking: A Meta-Analysis.","authors":"Jingjing Shi, Jie Lin, Wenqi Liu, Wanzhen Li, Haonan Zhu, Ningbo Yin, Hao Zheng, Yiyuan Gao, Maosheng Xu","doi":"10.1002/jmri.70120","DOIUrl":"https://doi.org/10.1002/jmri.70120","url":null,"abstract":"<p><strong>Background: </strong>A comprehensive assessment of normal reference values for right atrial (RA) and right ventricular (RV) strain derived from MR-feature tracking (MR-FT) is somewhat lacking.</p><p><strong>Purpose: </strong>To systematically review and meta-analyze reference values of RV and RA strain parameters using MR-FT in healthy adults and to identify their principal determinants.</p><p><strong>Study type: </strong>Meta-analysis.</p><p><strong>Population: </strong>A total of 4228 healthy adults from 40 studies (2322 male, age range: 18-79 years).</p><p><strong>Field strength/sequence: </strong>1.5 and 3.0 T/balanced steady-state free precession.</p><p><strong>Assessment: </strong>A systematic search of PubMed, Embase, and Web of Science identified studies on right heart strain in healthy adults published before January 1, 2025, by two investigators. A random-effects model aggregated RV and RA strain parameters. Subgroup and meta-regression analyses assessed the effects of race, sex, age, FT software, MR vendor, and field strength.</p><p><strong>Statistical tests: </strong>Random-effects model with pooled means and 95% confidence intervals, I² statistic, and Egger's test. p < 0.05 was considered significant.</p><p><strong>Results: </strong>The pooled means of RV global longitudinal, circumferential, and radial strain (RV-GLS, RV-GCS, and RV-GRS) were -22.57%, -14.16%, and 26.04%, respectively. The pooled RA reservoir, conduit, and booster strain (RA-εs, RA-εe, and RA-εa) were 47.01%, 28.24%, and 18.62%, respectively. Subgroup and meta-regression analyses identified race, sex, age, and FT software as contributing significantly to the variability in right heart measurements, while MR vendor (p = 0.437 for RV-GLS, 0.347 for RV-GCS, 0.240 for RV-GRS, 0.135 for RA-εs, 0.162 for RA-εe, and 0.287 for RA-εa) and field strength (p = 0.436 for RV-GLS, 0.041 for RV - GCS, 0.081 for RV-GRS, 0.926 for RA-εs, 0.377 for RA-εe, and 0.296 for RA-εa) had a limited impact.</p><p><strong>Date conclusion: </strong>This study provided the pooled normal values of RV and RA strain parameters in healthy adults using MR-FT and highlighted the considerable impact of race, sex, age, and FT software on right heart strain measurements.</p><p><strong>Level of evidence: 2: </strong></p><p><strong>Technical efficacy: </strong>Stage 5.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Predicting Breath Hold Task Compliance From Head Motion\".","authors":"Milan Toma","doi":"10.1002/jmri.70101","DOIUrl":"https://doi.org/10.1002/jmri.70101","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for \"Simultaneous Visualization of the Carotid and Subclavian Arteries Using Non-Contrast-Enhanced MR Angiography With a 3D Fast Field Echo Sequence and Time-Spatial Labeling Inversion Pulse: A Comparison With 3D Time-of-Flight MR Angiography\".","authors":"Mitsue Miyazaki","doi":"10.1002/jmri.70116","DOIUrl":"https://doi.org/10.1002/jmri.70116","url":null,"abstract":"","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}