Normal Reference Values and Determinants of Right Heart Strain Derived From MR-Feature Tracking: A Meta-Analysis.

IF 3.5 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Jingjing Shi, Jie Lin, Wenqi Liu, Wanzhen Li, Haonan Zhu, Ningbo Yin, Hao Zheng, Yiyuan Gao, Maosheng Xu
{"title":"Normal Reference Values and Determinants of Right Heart Strain Derived From MR-Feature Tracking: A Meta-Analysis.","authors":"Jingjing Shi, Jie Lin, Wenqi Liu, Wanzhen Li, Haonan Zhu, Ningbo Yin, Hao Zheng, Yiyuan Gao, Maosheng Xu","doi":"10.1002/jmri.70120","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>A comprehensive assessment of normal reference values for right atrial (RA) and right ventricular (RV) strain derived from MR-feature tracking (MR-FT) is somewhat lacking.</p><p><strong>Purpose: </strong>To systematically review and meta-analyze reference values of RV and RA strain parameters using MR-FT in healthy adults and to identify their principal determinants.</p><p><strong>Study type: </strong>Meta-analysis.</p><p><strong>Population: </strong>A total of 4228 healthy adults from 40 studies (2322 male, age range: 18-79 years).</p><p><strong>Field strength/sequence: </strong>1.5 and 3.0 T/balanced steady-state free precession.</p><p><strong>Assessment: </strong>A systematic search of PubMed, Embase, and Web of Science identified studies on right heart strain in healthy adults published before January 1, 2025, by two investigators. A random-effects model aggregated RV and RA strain parameters. Subgroup and meta-regression analyses assessed the effects of race, sex, age, FT software, MR vendor, and field strength.</p><p><strong>Statistical tests: </strong>Random-effects model with pooled means and 95% confidence intervals, I<sup>2</sup> statistic, and Egger's test. p < 0.05 was considered significant.</p><p><strong>Results: </strong>The pooled means of RV global longitudinal, circumferential, and radial strain (RV-GLS, RV-GCS, and RV-GRS) were -22.57%, -14.16%, and 26.04%, respectively. The pooled RA reservoir, conduit, and booster strain (RA-εs, RA-εe, and RA-εa) were 47.01%, 28.24%, and 18.62%, respectively. Subgroup and meta-regression analyses identified race, sex, age, and FT software as contributing significantly to the variability in right heart measurements, while MR vendor (p = 0.437 for RV-GLS, 0.347 for RV-GCS, 0.240 for RV-GRS, 0.135 for RA-εs, 0.162 for RA-εe, and 0.287 for RA-εa) and field strength (p = 0.436 for RV-GLS, 0.041 for RV - GCS, 0.081 for RV-GRS, 0.926 for RA-εs, 0.377 for RA-εe, and 0.296 for RA-εa) had a limited impact.</p><p><strong>Date conclusion: </strong>This study provided the pooled normal values of RV and RA strain parameters in healthy adults using MR-FT and highlighted the considerable impact of race, sex, age, and FT software on right heart strain measurements.</p><p><strong>Level of evidence: 2: </strong></p><p><strong>Technical efficacy: </strong>Stage 5.</p>","PeriodicalId":16140,"journal":{"name":"Journal of Magnetic Resonance Imaging","volume":" ","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Magnetic Resonance Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jmri.70120","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Background: A comprehensive assessment of normal reference values for right atrial (RA) and right ventricular (RV) strain derived from MR-feature tracking (MR-FT) is somewhat lacking.

Purpose: To systematically review and meta-analyze reference values of RV and RA strain parameters using MR-FT in healthy adults and to identify their principal determinants.

Study type: Meta-analysis.

Population: A total of 4228 healthy adults from 40 studies (2322 male, age range: 18-79 years).

Field strength/sequence: 1.5 and 3.0 T/balanced steady-state free precession.

Assessment: A systematic search of PubMed, Embase, and Web of Science identified studies on right heart strain in healthy adults published before January 1, 2025, by two investigators. A random-effects model aggregated RV and RA strain parameters. Subgroup and meta-regression analyses assessed the effects of race, sex, age, FT software, MR vendor, and field strength.

Statistical tests: Random-effects model with pooled means and 95% confidence intervals, I2 statistic, and Egger's test. p < 0.05 was considered significant.

Results: The pooled means of RV global longitudinal, circumferential, and radial strain (RV-GLS, RV-GCS, and RV-GRS) were -22.57%, -14.16%, and 26.04%, respectively. The pooled RA reservoir, conduit, and booster strain (RA-εs, RA-εe, and RA-εa) were 47.01%, 28.24%, and 18.62%, respectively. Subgroup and meta-regression analyses identified race, sex, age, and FT software as contributing significantly to the variability in right heart measurements, while MR vendor (p = 0.437 for RV-GLS, 0.347 for RV-GCS, 0.240 for RV-GRS, 0.135 for RA-εs, 0.162 for RA-εe, and 0.287 for RA-εa) and field strength (p = 0.436 for RV-GLS, 0.041 for RV - GCS, 0.081 for RV-GRS, 0.926 for RA-εs, 0.377 for RA-εe, and 0.296 for RA-εa) had a limited impact.

Date conclusion: This study provided the pooled normal values of RV and RA strain parameters in healthy adults using MR-FT and highlighted the considerable impact of race, sex, age, and FT software on right heart strain measurements.

Level of evidence: 2:

Technical efficacy: Stage 5.

由核磁共振特征追踪得出的正常参考值和右心应变的决定因素:一项荟萃分析。
背景:从磁共振特征跟踪(MR-FT)得出的右心房(RA)和右心室(RV)应变的正常参考值的综合评估有些缺乏。目的:系统回顾和荟萃分析健康成人RV和RA菌株参数的MR-FT参考值,并确定其主要决定因素。研究类型:荟萃分析。人群:来自40项研究的4228名健康成年人(2322名男性,年龄范围:18-79岁)。场强/序列:1.5和3.0 T/平衡稳态自由进动。评估:对PubMed、Embase和Web of Science进行系统检索,确定了2025年1月1日之前由两位研究者发表的关于健康成人右心压力的研究。随机效应模型汇总了RV和RA应变参数。亚组和元回归分析评估了种族、性别、年龄、FT软件、MR供应商和场强的影响。统计检验:随机效应模型,集合均值和95%置信区间,I2统计量和Egger检验。p结果:RV整体纵向、周向和径向应变(RV- gls、RV- gcs和RV- grs)的汇总平均值分别为-22.57%、-14.16%和26.04%。RA-εs、RA-εe和RA-εa分别为47.01%、28.24%和18.62%。亚组和meta回归分析发现,种族、性别、年龄和FT软件对右心测量的变异性有显著影响,而MR供应商(RV- gls的p = 0.437, RV-GCS的p = 0.347, RV- grs的p = 0.240, RA-εs的p = 0.135, RA-εe的p = 0.162, RA-εa的p = 0.287)和磁场强度(RV- gls的p = 0.436, RV-GCS的p = 0.041, RV- grs的p = 0.081, RA-εs的p = 0.926, RA-εe的p = 0.377, RA-εa的p = 0.296)的影响有限。结论:本研究使用MR-FT提供了健康成人右心和RA应变参数的汇总正常值,并强调了种族、性别、年龄和FT软件对右心应变测量的重要影响。证据等级:2;技术功效:第5阶段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
9.70
自引率
6.80%
发文量
494
审稿时长
2 months
期刊介绍: The Journal of Magnetic Resonance Imaging (JMRI) is an international journal devoted to the timely publication of basic and clinical research, educational and review articles, and other information related to the diagnostic applications of magnetic resonance.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信