Journal of Geriatric Psychiatry and Neurology最新文献

{"title":"Intranasal Oxytocin for Managing Agitation in a Patient of Mixed Dementia With Multiple Pathologies, Particularly With a History of Repetitive Head Injuries.","authors":"Naresh Jadav, Sümeyye Kuş, James Ellison, David Weisman, Mijail D Serruya","doi":"10.1177/08919887251382495","DOIUrl":"10.1177/08919887251382495","url":null,"abstract":"<p><p>BackgroundAgitation is common in persons living with dementia (major neurocognitive disorder) and worsens with disease progression. Brexpiprazole is the sole FDA-approved drug for agitation in persons with Alzheimer's dementia, but requires daily dosing over weeks. Limited pharmacologic options exist for acute agitation management.PurposeTo show the efficacy of oxytocin for acute agitation management in dementia patients.CaseWe report a 70-year-old former professional wrestler with repetitive head trauma who developed dementia and severe agitation. He showed remarkable, rapid improvement with as-needed intranasal oxytocin 30 IU until his death. Post-mortem examination revealed mixed pathology: Alzheimer's disease (Intermediate stage), Lewy Body disease (Limbic/Transitional stage), cerebrovascular disease with multiple infarcts, and chronic traumatic encephalopathy.ConclusionThis case demonstrates the potential efficacy of intranasal oxytocin for acute agitation management in persons living with mixed dementia and may inspire further investigation.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"426-430"},"PeriodicalIF":2.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Psychosis and Hallucinations Questionnaire in Lewy Body Dementia.","authors":"Chaminda Withanachchi Gunawardana, Peter G R Burke, Elie Matar, Simon J G Lewis","doi":"10.1177/08919887251395314","DOIUrl":"10.1177/08919887251395314","url":null,"abstract":"<p><p>BackgroundPsychotic symptoms are common in patients with Parkinson's Disease Dementia and Dementia with Lewy Bodies, known collectively as the Lewy Body Dementias (LBD). It is important to identify these symptoms early and accurately. However, these symptoms are challenging to identify and quantify in clinical practice. The Psychosis and Hallucinations Questionnaire (PsycH-Q) was developed as a self-report tool using patient-friendly language to assess hallucinations and related phenomena and has been previously validated in Parkinson's Disease patients without dementia and their caregivers.ObjectivesThis study aimed to evaluate the utility of the PsycH-Q in patients diagnosed with a Lewy Body Dementia.MethodsA total of 33 LBD patients, assisted by their caregivers, completed the PsycH-Q, along with the Scales for Outcomes in Parkinson's Disease-Psychiatric Complications (SCOPA-PC) and the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Items relating to hallucinations and psychotic phenomena from the SCOPA-PC and MDS-UPDRS were then compared with analogous ratings on the PsycH-Q.ResultsScores on the PsycH-Q were significantly correlated with SCOPA-PC Questions 1 and 3, as well as the MDS-UPDRS question 1.2 (Spearman's rho of 0.65, 0.73, and 0.47, respectively; p < 0.01 for all three correlations).ConclusionsThese results support the PsycH-Q as a patient-friendly questionnaire that accurately identifies hallucinatory phenomena and their features in LBD patients via self-report completed by patients with their caregivers. Future use of the PsycH-Q in clinical practice and research could improve early detection of psychotic symptoms in LBD patients, leading to improved management.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"368-379"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Caring on Psychological Wellbeing: A Qualitative Study in Carers of People Living With Behavioural-Variant Frontotemporal Dementia.","authors":"Isabella M Ocampo, Jemma Todd, Grace Wei, Fiona Kumfor","doi":"10.1177/08919887251401262","DOIUrl":"10.1177/08919887251401262","url":null,"abstract":"<p><p><b>Background:</b> Informal carers of people living with dementia can experience increased burden, stress and a decline in mental health and wellbeing. Growing evidence suggests these impacts are greater for those caring for individuals living with behavioural-variant frontotemporal dementia. However, little is known about their psychological needs and how these carers access psychological support. <b>Objective:</b> This study aimed to understand the impact of caring on psychological wellbeing and the experiences and needs of carers in seeking psychological support. <b>Methods:</b> Twelve carers participated in either a group or individual semi-structured interview. Data were analysed qualitatively using thematic analysis. <b>Results:</b> Five themes emerged: (1) <i>The job of being a carer</i>, (2) <i>The carer and person living with bvFTD as a unit</i>: <i>Reciprocal wellbeing & Care for the carers</i>, (3) <i>Feeling seen, Feeling heard, and Being connected</i>, (4) <i>The power of information</i> and (5) <i>Meaning and purpose through caring</i>. These themes captured the challenges, supports and meaningful aspects of the caring experience, and their impact on psychological wellbeing. While carers reported both positive and negative impacts of caregiving on their psychological wellbeing, they also highlighted a lack of tailored services in the context of behavioural-variant frontotemporal dementia. <b>Conclusions:</b> Psychological support services for carers should address common barriers to accessibility and flexibility and be developed in collaboration with carers to optimise feasibility and efficacy.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"534-548"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145573644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caregiver Reports of Lucid Episodes in Alzheimer's Dementia and Lewy Body Dementias.","authors":"Lauren R Bangerter, Kyungmin Kim, Yin Liu, Maria I Lapid, Jonathan Graff Radford, Joan M Griffin","doi":"10.1177/08919887261464594","DOIUrl":"10.1177/08919887261464594","url":null,"abstract":"<p><p>Purpose of ResearchLucidity is the transient recovery of abilities and communication that were seemingly lost among people living with dementia (PLWD). This study describes lucid episodes reported by Alzheimer's dementia (AD) and Lewy Body Dementias (LBD) caregivers. We analyzed survey data from 212 current AD (<i>n</i> = 191) and LBD caregivers who reported the frequency, duration, and characteristics of 653 lucid episodes witnessed in the past month.Major FindingsMost AD caregivers (67%) and LBD caregivers (81%) witnessed a lucid episode within the past month. LBD caregivers reported lucid episodes with greater changes in awareness and communication, compared to AD caregivers. LBD caregivers reported longer lucid episodes and that the PLWD knew about their change in lucidity, compared to AD caregivers.ConclusionsFindings suggest that differences in lucid episode intensity, timing, and meta-awareness between AD and LBD are possible and may inform care strategies for PLWD.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"8919887261464594"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Function and Insomnia Symptoms are Associated With Subjective-Objective Sleep Discrepancies in Older Adults Without Dementia.","authors":"Russell Calderon, Sofia Liu, Jing Huang, Miranda V McPhillips, Michelle Liu, Jiaying Li, Junxin Li","doi":"10.1177/08919887251403581","DOIUrl":"10.1177/08919887251403581","url":null,"abstract":"<p><p>BackgroundAccurate sleep assessment is key to promoting healthy aging, yet self-reported measures often diverge from actigraphy. The factors driving these discrepancies in older adults remain unclear.MethodsThis cross-sectional secondary analysis examined the prevalence and correlates of subjective-objective sleep discrepancies in 195 community-dwelling older adults (69.84 ± 6.83 years old, 78.97% women) without dementia using baseline data from two clinical trials. Time in bed (TIB), sleep onset latency (SOL), total sleep time (TST), and sleep efficiency were collected via ≥3 days of actigraphy, sleep diaries, and the Pittsburgh Sleep Quality Index (PSQI). Discrepancies were calculated as self-reported minus actigraphy values, using ±15 min (±15% for sleep efficiency) as thresholds. Validated scales assessed insomnia, sleepiness, pain, and depression. Computerized batteries assessed processing speed, attention, executive function, working memory, and episodic memory.ResultsDiscrepancies greater than ±15 min (or ±15%) were prevalent: 88.50% for TST, 81.25% for TIB (PSQI), 45.71% for TIB (diary), 45.87% for SOL, and 42.20% for sleep efficiency. Adjusted multinomial logistic regression revealed that more severe insomnia symptoms were significantly associated with reduced odds of over-reporting sleep efficiency on the PSQI (OR = 0.82, 95% CI [0.72, 0.94]). Although no longer significant after correcting for multiple comparisons, better verbal episodic memory was associated with greater odds of over-reporting sleep efficiency (OR = 2.11, 95% CI [1.10, 4.07]) and lower odds of under-reporting diary-based TIB (OR = 0.32, 95% CI [0.13, 0.76]).ConclusionCognitive function and insomnia are linked to sleep discrepancies and may affect perceived sleep quality, warranting careful interpretation of self-reported sleep in older adults.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"453-470"},"PeriodicalIF":2.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usability of the Rhode Island Mobile Cognitive Assessment Tool for Self-Administration in Detecting Cognitive Impairment in Older Adults.","authors":"Sydney C Sullivan, Melissa G Zammitti, Taylor Maynard, Kunal Mankodiya, Nicholas Constant, Laura E Korthauer, Brian R Ott, Charles Denby, Alyssa N De Vito, Geoffrey Tremont","doi":"10.1177/08919887251375475","DOIUrl":"10.1177/08919887251375475","url":null,"abstract":"<p><p>ObjectiveThis study evaluated the usability of the Rhode Island Mobile Cognitive Assessment Tool (RIMCAT), a proctored digital cognitive screening measure to assess its potential for self-administration.Methods100 participants (Healthy Controls [HC] <i>n</i> = 50; Cognitively Impaired [CI] <i>n</i> = 50) were recruited, and 90 completed the RIMCAT twice, with verbal prompts when necessary. Participants then completed an exit survey regarding their experience.ResultsAll HC completed the RIMCAT, but four CI individuals could not. Most finished in under 30 min. HC (M = 2.18, SD = 1.93) required significantly fewer prompts during the first RIMCAT administration compared to the CI group (M = 3.82, SD = 2.87). Both groups needed fewer prompts on the second visit, with prompts often related to input methods, button use, and instruction comprehension.ConclusionsThe RIMCAT shows promise for self-administration, particularly with minor modifications that could improve clarity, interface design, and user experience for optimal usability and self-administration.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"488-498"},"PeriodicalIF":2.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Care Experiences and Behaviours in People With Parkinson's Disease: A Meta-Synthesis.","authors":"Monica Petralito, Chiara Tedesco, Ercole Vellone, Silvia Cilluffo, Maura Lusignani, Stefano Terzoni, Andrea Zanichelli, Rosario Caruso, Gianluca Pucciarelli","doi":"10.1177/08919887251392139","DOIUrl":"10.1177/08919887251392139","url":null,"abstract":"<p><p>BackgroundParkinson's disease (PD) is the fastest-growing neurodegenerative condition globally, significantly impairing self-care capacity due to its complex motor and nonmotor symptoms. Caregiver involvement is often essential.ObjectiveThis review aims to synthesise qualitative evidence on self-care behaviours and experiences in individuals with PD, from both patient and caregiver perspectives.MethodsA qualitative meta-synthesis was conducted using Sandelowski and Barroso's methodology. Fifty-two eligible studies were analysed. Thematic categories were mapped onto Riegel's self-care framework: maintenance, monitoring, and management.ResultsSelf-care maintenance emerged as the most frequently reported dimension. Across all three dimensions, caregiver support played a central role in enabling effective symptom control and treatment adherence.ConclusionsThe synthesis highlights the critical importance of supporting self-care-especially maintenance behaviours-in PD management. It also emphasizes the vital role caregivers play in reinforcing self-care, pointing to the need for integrated support structures in clinical and research contexts.RegistrationThis review was registered in PROSPERO (https://www.crd.york.ac.uk/PROSPERO/view/CRD42024598072).</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"380-412"},"PeriodicalIF":2.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145504728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Baseline Pathological, Neuroimaging and Clinical Markers for Prognosis in Early Parkinson's Disease.","authors":"Angus McNamara, Benjamin Paul Ellul, Irina Baetu, Mark Jenkinson, Stephan Laurenz, Lyndsey Collins-Praino","doi":"10.1177/08919887251397641","DOIUrl":"10.1177/08919887251397641","url":null,"abstract":"<p><p>BackgroundCurrently, prognosis of Parkinson's Disease (PD) is limited. Emerging literature highlights potential of multi-modal biomarkers and neuroimaging to provide critical insight into clinical progression, potentially improving prediction of long-term outcomes.MethodsData were extracted from the Parkinson's Progression Markers Initiative (PPMI). Hierarchical clustering was applied to Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) scores at year-five follow-up, identifying two clusters. Differences in progression, as well as retrospective assessment of baseline differences, between clusters were explored for pathological biomarkers, neuroimaging, and prodromal measures. Additionally, logistic regression, receiver operating characteristic curve analyses and machine learning were employed to determine utility of variables at baseline as predictors of cluster membership.ResultsThe more impaired cluster demonstrated worse motor and non-motor outcomes, including higher rates of dementia and cognitive complaints at year-five, as well as more profound rigidity than cluster one. Further, retrospective comparisons showed cluster two performing worse in all prodromal measures and demonstrated lower striatal dopamine transporter and cognitive ability. Logistic regression determined that membership in this cluster was predicted by higher autonomic dysfunction and p-tau, along with reduced smell and alpha-syn, predicting 49.1% of variance (AUC = 0.92). This was significantly higher (<i>p</i> < 0.001) than the model including MDS-UPDRS scores alone, only accounting for 27.4% of variance (AUC = 0.74). Findings were corroborated by machine learning, whereby multi-modal assessment corresponded to 74% classification accuracy, compared to 60% with MDS-UPDRS alone.ConclusionPrediction of more marked impairment at year-five was substantially improved via multi-modal assessment, specifically, pathological biomarkers, suggesting that incorporating biomarkers into clinical criteria could enhance long-term prognosis.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"471-487"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145512992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Study to Characterize the Experiences of Patients and Caregivers With Dementia Diagnostic Disclosure Communication and Care Planning.","authors":"Joanna Paladino, Heily Chavez Granados, Jade A Connor Eruchalu, Carine Davila, Liliana Ramirez Gomez, Alissa Bernstein Sideman, Daniel Dohan, Elizabeth Lindenberger, Lindsay Dow, Ana-Maria Vranceanu, Deborah Blacker, Christine S Ritchie","doi":"10.1177/08919887251388036","DOIUrl":"10.1177/08919887251388036","url":null,"abstract":"<p><p>BackgroundClinician communication at the time of a dementia diagnosis often inadequately addresses patient and caregiver needs. We aimed to characterize the communication experiences of patients and caregivers affected by dementia using an evidence-based serious illness communication framework.MethodsWe conducted semi-structured interviews of patients with dementia and caregivers. An interdisciplinary research team used thematic content analysis to identify themes.ResultsParticipants included 6 patients and 15 caregivers recruited from the community and health care settings (n = 21; 17/21 female; n = 13 White (61%); n = 4 Black or African American (19%); n = 4 Latino/a (19%); n = 2 Asian; n = 2 other). Five themes were identified. First, perceptions of respectful or disrespectful communication affect the relationship with clinicians and contributes to positive or negative communication experiences. Second, participants described the emotional impact of sudden or unsupported disclosures, in which they felt unprepared to receive the news or emotionally abandoned after diagnosis. Third, the absence of, or ambiguity around, a definitive dementia diagnosis contributes to patient and caregiver distress and to feeling dismissed by clinicians. Fourth, mixed responses to illness education and clinician recommendations after disclosure reveals the need for more personalized and comprehensive care planning. Fifth, careful consideration around the timing of prognostic communication and advance care planning discussions is necessary to meet the needs of patients and caregivers with different emotional readiness, illness beliefs, and information preferences.ConclusionDementia diagnostic disclosure would benefit from a structured yet tailored communication approach that prioritizes respectful communication, emotional support, and comprehensive care planning to meet the needs of patients and caregivers.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"431-452"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13181747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145301477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging, Mental Health and Ethnic Disparities: Understanding Geriatric Mental Health in Western Nepal.","authors":"Mukesh Adhikari, Prayas Gautam, Sushrusha Arjyal, Binita Adhikari, Pratigya Gyawali, Sanjay Yadav, Theodore A Stern, Shreedhar Paudel","doi":"10.1177/08919887251403594","DOIUrl":"10.1177/08919887251403594","url":null,"abstract":"<p><p><b>Objective:</b> This study examined the prevalence of anxiety, low mental well-being, loneliness, depression, and insomnia among older adults in a district of western Nepal and identified factors associated with each of these conditions. <b>Methods:</b> A community-based cross-sectional study was conducted in Dang, Nepal from August 2023 to January 2024 among adults aged 60 years or older using purposive sampling technique (n = 814). Validated tools were used to assess each mental health conditions. Multivariate logistic regressions were conducted to identify factors associated with each condition. <b>Results:</b> Five percent of older adults had low mental well-being, 7.25% experienced loneliness, 14.13% showed signs of general anxiety disorder (GAD), 6.58% had depression, and 1.97% had insomnia. Older adults of <i>Dalit</i> ethnicity, those with chronic illnesses, and those with a family history of mental illness had a disproportionately higher odds of developing one or more mental health conditions compared with their counterparts. <b>Conclusion:</b> Mental health conditions such as anxiety, depression, sleep difficulties and loneliness, and low mental well-being were less prevalent in Dang compared to previous studies in Nepal, and were associated with caste, chronic illnesses, and family history of mental illnesses. These findings highlight the need for targeted mental health screening and culturally sensitive interventions-such as community-based programs that acknowledge caste-based stigma, strengthen family and social support systems, and integrate local language counseling- to address mental health needs of vulnerable older adults. Future nationally representative studies are needed to provide a broader understanding of mental health among older adults in Nepal.</p>","PeriodicalId":16028,"journal":{"name":"Journal of Geriatric Psychiatry and Neurology","volume":" ","pages":"499-512"},"PeriodicalIF":2.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13103349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}