Journal of Health, Population, and Nutrition最新文献

{"title":"Healthy eating behaviors may be associated with lower risk of premature coronary artery disease: A multi-center case-control study.","authors":"Ehsan Shirvani, Noushin Mohammadifard, Mahshid Keshavarz, Fereshteh Sattar, Motahare Bateni, Ehsan Zarepur, Fahimeh Haghighatdoost, Samad Ghaffari, Nahid Salehi, Masoud Lotfizadeh, Nahid Azdaki, Ahmadreza Assareh, Mahboobeh Gholipour, Masoumeh Sadeghi, Alireza Khosravi Farsani, Nizal Sarrafzadegan","doi":"10.1186/s41043-025-00869-4","DOIUrl":"https://doi.org/10.1186/s41043-025-00869-4","url":null,"abstract":"<p><strong>Background: </strong>Despite some evidence on individual eating habits in relation to cardiovascular disease, little is known about the combination of common eating habits in relation to premature coronary artery disease (PCAD).</p><p><strong>Objective: </strong>We investigated the association between a combined eating habits score (EHS) and PCAD risk.</p><p><strong>Methods: </strong>In this case-control study, 2022 patients with PCAD and 1063 healthy control were recruited. Women aged between 18 and 70 and men aged between 18 and 60 years were eligible. PCAD was defined as 75% or more stenosis in a single coronary artery disease or at least 50% in the left main coronary artery. Eating habits were assessed through interview and higher scores represent healthier behaviors.</p><p><strong>Results: </strong>Participants in the fourth quartile of EHS had 22% lower risk of PCAD than those in the first quartile (95% CI: 0.61, 0.99; P = 0.024). Not adding salt at the table (OR = 0.80, 95% CI: 0.66, 0.97; P = 0.023), low-salt meals (OR = 0.75, 95% CI: 0.57, 0.99; P = 0.022), and slow eating (OR = 0.42, 95% CI: 0.24, 0.71; P < 0.001) were associated with lower risk of PCAD while more water drinking (OR = 1.56, 95% CI: 1.07, 2.27; P = 0.013), and increased meal frequency (OR = 1.85, 95% CI: 1.09, 3.13; P = 0.025) were linked with increased risk of PCAD.</p><p><strong>Conclusion: </strong>Healthy eating behaviors score, particularly low salt intake and slow eating were associated with lower risk of PCAD. However, higher meal frequency and more water drinking were associated with increased risk of PCAD. Well-designed prospective cohort studies are required.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"128"},"PeriodicalIF":2.4,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between plant-based diet indices and the risk of breast cancer: a case-control study.","authors":"Fateme Souni, Fatemeh Mansouri, Fatemeh Jafari, Reza Sharifi, Sepideh PourvatanDoust, Zainab Shateri, Mehran Nouri, Bahram Rashidkhani","doi":"10.1186/s41043-025-00879-2","DOIUrl":"https://doi.org/10.1186/s41043-025-00879-2","url":null,"abstract":"<p><strong>Background: </strong>Previous studies examining the relationship between plant-based diets and breast cancer (BrC) have provided conflicting evidence. To address these inconsistencies, we aimed to evaluate the association between the plant-based diet index (PDI), healthful PDI (hPDI), and unhealthy PDI (uPDI) with the odds of BrC in Iranian women.</p><p><strong>Methods: </strong>The current case-control research was performed on 133 Iranian women with BrC and 265 controls. The study subjects were selected from hospitals in Tehran. PDI, hPDI, and uPDI were categorized into eighteen food groups based on nutrient composition similarity. The relationship between PDIs and BrC was assessed using logistic regression.</p><p><strong>Results: </strong>After adjusting for confounding factors, the chance of developing BrC was lower in the highest tertile of hPDI compared to the lowest tertile (odds ratio (OR) = 0.495; 95% confidence interval (CI): 0.274-0.891; P = 0.019). In addition, postmenopausal women in the second and last tertiles of hPDI had lower odds of BrC than those in the first tertile (T) (T₂: OR = 0.342; 95% CI: 0.141-0.828; P = 0.017- T₃: OR = 0.262; 95% CI: 0.107-0.639; P = 0.003) in the adjusted model. Furthermore, in premenopausal women in the highest tertile of uPDI, the odds of BrC were increased compared to the lowest tertile (OR = 2.546; 95% CI: 1.051-6.167; P = 0.038) in the adjusted model.</p><p><strong>Conclusions: </strong>Adherence to a healthy plant-based dietary pattern, including vegetables, fruits, whole grains, nuts, and legumes, seems to be beneficial for BrC prevention, particularly in postmenopausal women. Future prospective cohort studies that consider menopausal status and the type of BrC are needed to support these findings.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"127"},"PeriodicalIF":2.4,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pooled estimates of stillbirth in Ethiopia: systematic review and meta-analysis, 2013-2024.","authors":"Ahmed Tahir Ahmed, Mohamed Arab Abdilahi, Abdulahi Haji Abas, Habon Bade Ali","doi":"10.1186/s41043-025-00877-4","DOIUrl":"https://doi.org/10.1186/s41043-025-00877-4","url":null,"abstract":"<p><strong>Background: </strong>Stillborn babies are those that are born with no signs of life at or after 28 weeks of gestation or weighing more than 1000 g. It is a public health problem that is overlooked in the global agenda. Individual studies have been conducted with different estimates across countries, making it difficult to understand the national stillbirth rate. Thus, this study aims to better understand stillbirth in Ethiopia and inform policy makers by producing pooled estimates.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were performed between 2013 and 2024 in accordance with the PRISMA guidelines. The outcomes of interest in the English language were exhaustively searched in different databases, such as PubMed/Medline, Science Direct, HINARI and Google Scholar. Data selection, extraction and quality assessment were performed by two authors independently. Zotero was used for study selection, whereas all the statistical analyses were performed with MEDCALC version 23.2.1 software.</p><p><strong>Result: </strong>Among a total of 1007 studies found in databases and manual citation searches, 35 studies were included in the analysis. The overall pooled stillbirth rate was 68 (95% confidence interval (CI) 52-85) per 1000 births in Ethiopia. Subgroup analysis revealed discrepancies in rates across regions, study years and settings. Subgroup analysis revealed that the pooled estimate of the stillbirth rate of recent studies (2021-2024) is 72 (95% CI, 48-100) per 1000 births, which is higher than the rate of earlier studies (2013-2020), with a rate of 63 (95% CI, 38-93) per 1000 births.</p><p><strong>Conclusion: </strong>The pooled estimate of the stillbirth rate is high in Ethiopia compared with the global target stillbirth rate of 12 per 1000 births, which is set for 2030 and is also higher than African countries. The stillbirth rate has also increased over time in Ethiopia. This might be due to poor maternal health access and utilization, including a significant rate of iodine deficiency, among pregnant women in Ethiopia. The review informs policy makers and program implementers about the burden of stillbirth in Ethiopia. All health sector actors should adjust and improve the quality of maternal health services, with attention given to stillbirth to reach the global target.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"126"},"PeriodicalIF":2.4,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival status and predictors of mortality among children with severe acute malnutrition admitted to public health facilities at Hawassa City, Southern Ethiopia: a retrospective cohort study.","authors":"Bargude Balta, Bedilu Bekele, Eyosafet Abera Asefa, Alemu Bogale","doi":"10.1186/s41043-025-00814-5","DOIUrl":"https://doi.org/10.1186/s41043-025-00814-5","url":null,"abstract":"<p><strong>Background: </strong>Despite improvements in child health and nutrition in Ethiopia, undernutrition remains a critical issue, causing half of child deaths. Many severely malnourished children seek treatment at therapeutic feeding centers, but a significant number still die in stabilization centers. This study aimed to estimate survival rates and identify predictors of mortality among children with severe acute malnutrition admitted to public health facilities in Hawassa City, Southern Ethiopia.</p><p><strong>Objective: </strong>The main aim of this study was to estimate survival status and predictors of mortality among children with severe acute malnutrition admitted to public health facilities at Hawassa City, Southern Ethiopia.</p><p><strong>Method: </strong>A facility-based retrospective cohort study was employed to estimate survival status and predictors among under-five children with severe acute malnutrition admitted to selected health facilities. A total of 476 randomly selected under-five children with SAM from January 2018 to December 31, 2021, participated in the study. Data were analyzed by SPSS IBM version 26. Bivariable and multivariable Cox regression models assessed risk factors. Kaplan- Maier Curve and Long rank test were used to estimate cumulative survival probability and to compare survival status probability across different groups.</p><p><strong>Results: </strong>Over the 3-year observation period, the overall survival status was, (84.7%), [95% CI; 81.2, 87.8]. The incidence density of death was 3.8/100 person-day. The overall median survival time was 34 [95% CI 32.2-37.5] days. After controlling for other factors, a child who had co-morbidities [AHR = 3.305, 95%; CI: (1.1, 10.9)], and Albendazole [AHR = 5.3, 95%; CI: (1.3, 21.7)] were identified as the independent predictors of the time to death.</p><p><strong>Conclusion: </strong>The findings of this study confirm the mortality rate was higher than in most national studies. A significantly low recovery rate was identified for the children with co-morbidities and those who had not been dewormed. Expanding the immunization programs and deworming programs regularly which link nutrition interventions was recommended to raise the recovery rate.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"125"},"PeriodicalIF":2.4,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, and practices on urinary schistosomiasis among schoolchildren in Ethiopia: cross-sectional study.","authors":"Ketema Deribew, Delenasaw Yewhalaw, Zeleke Mekonnen","doi":"10.1186/s41043-025-00813-6","DOIUrl":"https://doi.org/10.1186/s41043-025-00813-6","url":null,"abstract":"<p><strong>Background: </strong>Urinary schistosomiasis is a disease caused by Schistosoma haematobium and is one of the public health problems in Ethiopia. When developing specific schistosomiasis control intervention program, the existing knowledge, attitudes and practices (KAPs) must be taken into account. This study aimed to assess the KAPs of primary schoolchildren towards urinary schistosomiasis in Ethiopia.</p><p><strong>Methods: </strong>A total of 1171 study participants aged 5 to 15 years were selected randomly.</p><p><strong>Results: </strong>Of the 1171 interviewed schoolchildren, 654, or 55.8%, said they had heard of urinary schistosomiasis. Using river or dam water for household consumption had association with urinary schistosomiasis infection history (P = 0.001). Logistic regression analysis showed that males had higher risk of getting urinary schistosomiasis infection compared to females (OR = 3.01, P < 0.001). Children in low socio-economic status had higher risk of having urinary schistosomiasis compared to high socio-economic status (OR = 2.81, P < 0.001). Compared to urban dweller, children in rural area had higher risk of having urinary schistosomiasis (OR = 4.34, P < 0.001). Respondents who used river water (OR = 2.48, P = 0.005) and lake or dam water (OR = 3.33, P = < 0.001) were at higher risk of urinary schistosomiasis infection. Furthermore, respondents swimming or playing in river water had higher risk of urinary schistosomiasis infection history (OR = 1.62, P = 0.005).</p><p><strong>Conclusions: </strong>There was knowledge gap in schoolchildren about urinary schistosomiasis causes, transmission, symptoms and prevention. Therefore, appropriate health education and behavioral change intervention is needed to create better knowledge and practices in children to prevent and control urinary schistosomiasis. Health organizations and policy makers should contribute to improve knowledge at the school as well as community level.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"123"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive role of neutrophil-percentage-albumin ratio (NPAR) in overactive bladder (OAB) in adults in the United States: a cross-sectional study.","authors":"Mingchu Jin, Heng Liu, Jie Xu, Yu Zhou, Haidong Hao, Yutang Yuan, Hongtao Jia","doi":"10.1186/s41043-025-00817-2","DOIUrl":"https://doi.org/10.1186/s41043-025-00817-2","url":null,"abstract":"<p><strong>Background: </strong>There is mounting evidence suggesting a direct connection between inflammatory responses and the pathophysiology of overactive bladder (OAB). However, conventional inflammatory markers do not directly indicate a correlation with OAB. Therefore, our goal was to investigate the relationship between OAB and a novel inflammatory marker, the neutrophil percentage-to-plasma-albumin ratio (NPAR).</p><p><strong>Methods: </strong>This study included 28,906 participants from the 2005-2018 National Health and Nutrition Examination Survey (NHANES). Weighted multivariate regression models and multiple regression equations were applied to evaluate the correlation between NPAR and OAB. Additionally, to evaluate the possibility of a linear relationship between NPAR and OAB, smoothed curve fitting was used. Sensitivity and stratified analyses were conducted to assess the robustness of the results.</p><p><strong>Results: </strong>The final sample size consisted of 28,906 individuals, with an overall OAB prevalence of 24.6%. Using a weighted multivariate logistic model and adjusting for multiple covariates, we identified a strong association between NPAR and OAB (OR 1.074, 95% CI 1.06-1.08). Individuals in the highest NPAR quartile had a 32% greater prevalence of OAB compared to those in the lowest quartile. Smoothed curve fitting showed a nonlinear connection between NPAR and OAB, and the effect sizes remained consistent across specific subgroups (P for interaction < 0.05).</p><p><strong>Conclusion: </strong>The incidence of OAB was shown to positively correlate with higher NPAR levels in this investigation. NPAR might be a useful and affordable biomarker for determining who is at risk for OAB, facilitating timely intervention.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"122"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Adherence to standard infection prevention and control practices and factors associated among healthcare workers at Juba Teaching Hospital, Juba-South Sudan: a cross-sectional study.","authors":"Chubang Augustine Khamsa, John Bosco Isunju, Harriet M Babibako, Fred Nuwaha Ntoni","doi":"10.1186/s41043-025-00867-6","DOIUrl":"https://doi.org/10.1186/s41043-025-00867-6","url":null,"abstract":"","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"121"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of non-communicable diseases in South Asia: a decomposition analysis.","authors":"Jalandhar Pradhan, Manacy Pai, Rinshu Dwivedi, Bijeta Mishra, Sasmita Behera, Tapas Bera, Rockli Kim, S V Subramanian","doi":"10.1186/s41043-025-00827-0","DOIUrl":"https://doi.org/10.1186/s41043-025-00827-0","url":null,"abstract":"<p><strong>Background: </strong>This study examines the incidence, prevalence, deaths, and disability-adjusted life years (DALYs) related to non-communicable diseases (NCDs) in South Asia, exploring the environmental, metabolic, and behavioural risk factors, and exploring changes in deaths and DALYs driven by population growth, aging, and mortality rates.</p><p><strong>Methods: </strong>Using data from the Global Burden of Disease (GBD) study 2021, we estimated age-standardized incidence, prevalence, deaths, and DALYs for four major NCDs: cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases from 2010 to 2021. Gender and age-specific estimations were conducted across all NCDs, with 95% uncertainty intervals and a decomposition analysis was employed to estimate change in death and DALYs attributable to NCDs.</p><p><strong>Findings: </strong>The burden of NCDs in South Asia increased by 3.00% in incidence from 2010 to 2021, while overall prevalence decreased by 1.00%, yet the age-standardized prevalence rate remains above the global rate (91,570 per 100,000 population). Incidences of cardiovascular and respiratory diseases declined by 3.00% and 13.00%, respectively, whereas diabetes and cancer rose by 21.00% and 13.00% in South Asia. Nepal faced the highest environmental impact (23.4% of DALYs), Bangladesh the greatest metabolic impact (25.62%), and India the highest from behavioural factors (23.95%). Population growth and aging were primary drivers of changes in deaths and DALYs across the region.</p><p><strong>Conclusion: </strong>This finding emphasizes the need for targeted public health interventions addressing environmental, metabolic, and behavioral risks for NCDs in South Asia, alongside strategies to support healthy aging and effective disease management across diverse demographic groups.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"124"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between dietary inflammatory index and risk of chronic kidney disease and low glomerular filtration rate; a systematic review and meta-analysis of observational studies.","authors":"Amirhossein Ataei Kachouei, Frazam Kamrani, Neda S Akhavan, Fahimeh Haghighatdoost","doi":"10.1186/s41043-025-00872-9","DOIUrl":"https://doi.org/10.1186/s41043-025-00872-9","url":null,"abstract":"<p><strong>Objective: </strong>Earlier studies on the association between the dietary inflammatory index (DII) and the risk of chronic kidney disease (CKD) and low estimated glomerular filtration rate (low-eGFR) have provided uncertain findings. Therefore, this study aimed to summarize the existing literature on the association between DII and CKD and low-eGFR.</p><p><strong>Methods: </strong>In April 2024, PubMed, Scopus, and Web of Science were searched for observational studies, along with manual inclusion of Google Scholar and Embase. The review was submitted to PROSPERO (CRD42024536756) and conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines. Studies which reported risk for CKD or low-eGFR were included.</p><p><strong>Results: </strong>The random-effects model was used for statistical analysis and pooled effect sizes were reported as odds ratios (ORs) and their corresponding 95% confidence intervals (CIs). A total of 13 studies, all with a cross-sectional design, were identified eligible for inclusion in the meta-analysis. The results revealed that higher DII scores were associated with significantly higher odds of CKD (OR: 1.36, 95% CI: 1.20-1.56, p < 0.001) and low-eGFR (OR: 1.58, 95% CI: 1.26-2.00, p = 0.001).</p><p><strong>Conclusion: </strong>This study found a significant positive association between the DII and the odds of CKD and low-eGFR, suggesting a higher likelihood of CKD in individuals who adhere to a pro-inflammatory diet. Large-scale prospective cohort studies are required to confirm these findings, particularly by assessing different indicators of kidney function.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"120"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between life's simple 7 and peripheral neuropathy among U.S. adults, a cross-sectional study.","authors":"Xi Gu, Fanfan Zhu, Ping Gao, Ying Shen, Leiqun Lu","doi":"10.1186/s41043-025-00864-9","DOIUrl":"https://doi.org/10.1186/s41043-025-00864-9","url":null,"abstract":"<p><strong>Background: </strong>Peripheral neuropathy (PN) is a common disease among adults that can lead to severe clinical outcomes; Life's Simple 7(LS7) is recommended to reduce the risk of cardiovascular disease and stroke. However, the association between LS7 and PN has not been well studied yet.</p><p><strong>Methods: </strong>We enrolled 4634 adults aged 40 to 85 years from the National Health and Nutrition Examination Survey (NHANES) 1999-2004. We used univariable and multivariable logistic regression models to evaluate the association between the LS7 score and PN. The LS7 score was treated as a continuous variable and divided into three groups: inadequate (0-7), average (8-10), and optimal (11-14). Subgroup analyses were also performed.</p><p><strong>Results: </strong>The average age of the participants was 55.28(0.24) years, and 684(11.59%) of those were diagnosed with PN. In three models, the inverse associations between LS7 and PN were found. In Model 3, a point increase in the LS7 score was associated with a 9% decreased incidence of PN, the odds ratio (OR) was 0.91, and the 95% confidence interval (CI) was 0.86 to 0.97. Compared with the inadequate LS7 score group, participants in the average and optimal groups were less likely to have PN, and the OR and 95%CI were 0.75(0.59,0.96) and 0.47(0.28,0.79), respectively. No significant interactions were found in the subgroup analyses.</p><p><strong>Conclusion: </strong>An increased LS7 score is inversely associated with the likelihood of PN. This benefit was observed predominantly in participants who had the optimal LS7 score.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"118"},"PeriodicalIF":2.4,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}