Journal of Health, Population, and Nutrition最新文献

{"title":"The association between nutrients intake, diet quality and food insecurity with depression in patients with coronary artery disease.","authors":"Mohammad Dehghani, Javad Kojuri, Afsane Ahmadi, Morteza Zare, Atefe Bonyadian, Najmeh Hejazi","doi":"10.1186/s41043-025-00944-w","DOIUrl":"https://doi.org/10.1186/s41043-025-00944-w","url":null,"abstract":"<p><strong>Aim: </strong>Depression is a prevalent mental health disorder in patients with cardiovascular disease worldwide. The purpose of this observational study was to determine the association between nutrients intake, food insecurity, and diet quality with depression in patients with coronary artery diseases (CAD).</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted on 225 coronary artery patients. Nutrients intake, diet quality (by calculating Framingham Nutrition Risk Score (FNRS)), food insecurity and depression status of patients were obtained by using standard validated questionnaires. Relevant statistical analyses including logistic regression were used to analyze all data. P-value ≤ 0.05 was considered significant.</p><p><strong>Results: </strong>The multivariate-adjusted regression model showed that a higher intake of total fat (P = 0.02, OR = 1.031) increases the odds of depression. However, a higher intake of PUFA and Vitamin B12 was associated with its lower odds. (P = 0.005, OR = 0.87 and P = 0.005, OR = 0.73, respectively). It also indicated food insecurity was associated with depression in CAD patients (P < 0.001, OR = 6.92). FNRS could not show any significant association.</p><p><strong>Conclusion: </strong>This study indicated that the dietary intake of PUFA and vitamin B12 were negatively associated with depression, while the intake of total fat from diet was directly associated with depression and might be considered as a risk factor in CAD patients. Furthermore, food insecurity was strongly and positively associated with depression in these patients. However, diet quality based on FNRS was not associated with depression among patients with CAD.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"205"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological trends and burden of metabolic dysfunction-associated steatotic liver disease in the Middle East and North Africa region: a 32-year analysis of health impact.","authors":"Zahra Sarkoohi, Mohammad-Mahdi Bastan, Mohammad Amin Khajuei Gharaei, Mahsa Iranmanesh, Arya Adinepour, Reyhane Khajezade, Faegheh Bahri, Fatemeh Akhlaghi, Azin Kadkhodamanesh, Hossein Pourghadamyari, Hamid Sharifi, Omid Eslami, Seyed Aria Nejadghaderi","doi":"10.1186/s41043-025-00973-5","DOIUrl":"https://doi.org/10.1186/s41043-025-00973-5","url":null,"abstract":"<p><strong>Background: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a condition marked by excess liver fat, ranging from simple steatosis to non-alcoholic steatohepatitis. Updated reports on the epidemiology of MASLD in the Middle East and North Africa (MENA) region are needed. This study aimed to report the trends in the MASLD burden in the MENA region from 1990 to 2021, as well as age and sex patterns and their association with the sociodemographic index (SDI).</p><p><strong>Methods: </strong>Data on the incidence, prevalence, disability-adjusted life years (DALYs), and mortality of MASLD in 21 countries within the MENA region from 1990 to 2021 were extracted from the GBD 2021 study. The relationship with the SDI and the burden attributable to risk factors, such as high fasting plasma glucose and smoking, were examined.</p><p><strong>Results: </strong>Between 1990 and 2021, the MENA region experienced a 13.8% increase in the age-standardized incidence rate, reaching 1,037.6 per 100,000 population. The age-standardized prevalence saw a rise of 26.4%. Women experienced a higher increase in incidence than men. The highest rates of DALYs were observed among older adults. Countries with a high SDI faced a greater disease burden. High fasting plasma glucose accounted for the largest burden of MASLD.</p><p><strong>Conclusions: </strong>The study found that the incidence and prevalence of MASLD in the MENA region increased significantly from 1990 to 2021, especially in areas with high SDI. High fasting plasma glucose was the most significant attributable risk factor, highlighting the need for metabolic interventions.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"207"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Self-management in patients with metabolic dysfunction-associated steatotic liver disease: influencing factors and impact on readmission.","authors":"Xiuli Lin, Shaorui Bao, Yueting Yu, Haiping Huang, Meichun Shu","doi":"10.1186/s41043-025-00936-w","DOIUrl":"https://doi.org/10.1186/s41043-025-00936-w","url":null,"abstract":"","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"204"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national burden of uterine cancer among women aged 50 years and older from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.","authors":"Tingting Feng, Wei Li, Qin Wang, Jing Yang, Fujin Shen","doi":"10.1186/s41043-025-00915-1","DOIUrl":"https://doi.org/10.1186/s41043-025-00915-1","url":null,"abstract":"<p><strong>Background: </strong>Uterine cancer poses a growing global health threat, with rising incidence among women aged ≥ 50 years. This study aimed to evaluate its disease burden across regions and nations.</p><p><strong>Methods: </strong>Using Global Burden of Disease 2021 data, we analyzed the incidence, mortality, disability-adjusted life years (DALYs), and trends via estimated annual percentage change (EAPC), decomposition, inequality analyses, and Bayesian Age-Period-Cohort modeling for 2022-2040 projections.</p><p><strong>Results: </strong>In 2021, global uterine cancer cases among women ≥ 50 years reached 414,754 (95% UI: 370,388-453,502), causing 90,509 deaths (95% UI: 78,633-101,441) and 2,189,261 DALYs (95% UI: 1,920,396-2,446,737). Age-standardized incidence rate (ASIR) rose (EAPC = 0.56, 1990-2021), while mortality and DALYs declined. High-income North America had the highest ASIR (128/100,000), with the United States, China and Russia leading new cases. High Socio-demographic index (SDI) regions exhibited widening disparities, evidenced by a 21% increase in the slope index of inequality (SII) for incidence (47 in 1990 to 57 in 2021) and concentration indices (CI) rising from 0.33 (95% CI: 0.28, 0.37) in 1990 to 0.35 (95% CI: 0.29, 0.4) in 2021. Population growth drove 132.55% of DALY changes, outweighing epidemiological (-32.95%) and aging (0.4%) factors. Projections suggest declining ASIR, the age-standardized mortality rate (ASMR), and DALY rates by 2040, yet absolute cases will rise to 617,571 new cases, 131,961 deaths, and 2,851,768 DALYs.</p><p><strong>Conclusions: </strong>Despite declining mortality and DALY rates, uterine cancer incidence continued to increase globally, driven by population growth. High-income regions faced disproportionate burdens, with persistent health inequities. Projected absolute case growth demands urgent prioritization of equity-oriented screening, prevention, and resource allocation. Governments must integrate targeted interventions with global aging policies to address this dual burden of epidemiological transition and health inequity.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"208"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary niacin intake and mortality outcomes in hypertensive populations: analysis from NHANES 2003-2016.","authors":"Long Yang, Xia Shen, Zulihuma Seyiti, Jing Tang, Jiande Lu, Abudushalamu Kasimujiang, Zhangming Deng, Tengchao Yang, Yanyang Zheng, Chenmeng Liu, Xiao-Ming Gao, Xue-Feng Shan","doi":"10.1186/s41043-025-00976-2","DOIUrl":"https://doi.org/10.1186/s41043-025-00976-2","url":null,"abstract":"<p><p>The rising prevalence of hypertension underscores the urgent need for effective management strategies. While niacin-based medications and supplements have shown promise in improving outcomes among patients with hypertension, the impact of dietary niacin intake on prognosis remains an area requiring further investigation. Using data from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2016, this study examined the association between dietary niacin intake and mortality risk among 13,237 individuals with hypertension. During a median follow-up of 103 months, 3,151 participants (23.80%) died from all causes, and 864 (7.89%) died from cardiovascular diseases. In multivariable-adjusted Cox proportional hazards models, dietary niacin intake was independently associated with a lower risk of both all-cause mortality (HR = 0.993, 95% CI: 0.986-1.000, p = 0.036) and cardiovascular mortality (HR = 0.984, 95% CI: 0.971-0.997, p = 0.017). Niacin intake was categorized into quartiles: Q1 (< 15.5 mg/day), Q2 (15.5-21.1 mg/day), Q3 (21.1-28.2 mg/day), and Q4 (> 28.2 mg/day). Cox regression analysis indicated that participants in the Q3 group had a significantly lower risk of all-cause mortality compared to those in Q1 (HR = 0.788, 95% CI: 0.657-0.944, p = 0.010). Moreover, restricted cubic spline (RCS) analysis revealed a U-shaped association between dietary niacin intake and all-cause mortality (P for nonlinearity = 0.016). These findings highlight the potential benefits of dietary niacin in reducing mortality risk among hypertensive individuals and suggest that moderate increases in dietary niacin intake may represent a feasible strategy for reducing mortality risk in this population.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"206"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary glycemic index, glycemic load, and risk of COVID-19: a prospective cohort study.","authors":"Elahe Shamshirgardi, Seyed Jalil Masoumi, Asma Kazemi, Mehran Nouri, Zeynab Shahsavani, Cain C T Clark, Mehrdad Behzadi, Marzieh Akbarzadeh","doi":"10.1186/s41043-025-00958-4","DOIUrl":"https://doi.org/10.1186/s41043-025-00958-4","url":null,"abstract":"<p><strong>Background: </strong>Considering the associations of insulin resistance and glycemic control with immunity, the present study sought to evaluate the association between dietary glycemic index (GI) and glycemic load (GL), as the main dietary determinants of these conditions, with the risk of COVID-19 infection in the participants of Shiraz University of Medical Sciences employees' health cohort.</p><p><strong>Methods: </strong>In this prospective study, data from 3319 cohort study participants were analyzed. Demographic, anthropometric and dietary intake data were collected at the time of recruitment. Dietary GI and GL were calculated based on the data from the food frequency questionnaire. In the follow-ups, data on COVID-19 infection were recorded. To investigate the associations between dietary GI and GL with COVID-19, Cox regression statistics were used. Analysis of variance was used to compare the rate of COVID-19 infection in the tertiles of GI and GL.</p><p><strong>Results: </strong>The mean age of the participants was 40.92 ± 6.99 years. Of these, 210 cases with COVID-19 were recorded. The hazard ratios of COVID-19 infection in the second and third tertile of the GI were 3.44 (95% CI = 2.13-5.55) and 6.45 (95% CI = 4.11-10.12) times greater than in the first tertile, respectively. Also, this risk ratio in the second and third tertile of the GL was 8.78 (95% CI = 4.62-16.69) and 54.04 (95% CI = 27.18-107.46) times more than in the first tertile.</p><p><strong>Conclusions: </strong>The present study showed a higher risk of COVID-19 infection in higher tertiles of dietary GI and GL.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"203"},"PeriodicalIF":2.4,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report on a foodborne outbreak of Streptococcus dysgalactiae Subsp. equisimilis in China.","authors":"Junhong Li, Bowen Tu, Xujian Mao, Ying Zhao, Qiang Du, Fengming Wang, Cong Chen, Hongbing Tang, Junmin Ji, Hongmei Yang","doi":"10.1186/s41043-025-00957-5","DOIUrl":"10.1186/s41043-025-00957-5","url":null,"abstract":"<p><strong>Introduction: </strong>Streptococcus dysgalactiae subsp. equisimilis (SDSE), a Gram-positive, beta-hemolytic group G Streptococcus, possesses virulence factors such as M protein, streptolysin O, streptolysin S, streptokinase, and hyaluronidase. This study reports a foodborne outbreak caused by SDSE infection recently occurred in China.</p><p><strong>Methods: </strong>In April 2019, an acute tonsillitis outbreak involving 155 patients occurred in a company in Changzhou, Jiangsu Province, China. Epidemiological surveys and laboratory investigations were conducted to identify the cause.</p><p><strong>Results: </strong>All patients were clinically diagnosed with acute suppurative tonsillitis or acute pharyngitis. SDSE was identified as the causative pathogen, isolated form 81.4% (35/43) of patients, 12.5% (1/8) of canteen staff, and 33.3% (1/3) of tested food samples (fried meat). Multilocus sequence typing (MLST) and emm typing confirmed all isolates as ST98-stG480.0, suggesting contamination of fried meat by an SDSE-carrying canteen staff member as the source of the outbreak. The mean onset time was 45.8 h, with an SDSE prevalence rate of 27.2%.</p><p><strong>Conclusions: </strong>This study is the first to report a foodborne outbreak caused by SDSE in Changzhou city since 2003. The identified strain, ST98-stG480.0, was exclusively associated with respiratory infections and exhibited no gastrointestinal symptoms. These findings underscore the importance of enhanced surveillance and in-depth investigation into the characteristics and public health implications of this strain.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"201"},"PeriodicalIF":2.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial effects of ginger on prevention of obesity through Modulation of gut microbiota.","authors":"Negar Ghashghaei, Asma Rashki Kemmak, Elham Goli, Shima Shishebor Astaneh, Monir Dahri, Mohammad Reza Mazaheri Habibi","doi":"10.1186/s41043-025-00953-9","DOIUrl":"10.1186/s41043-025-00953-9","url":null,"abstract":"<p><strong>Background: </strong>The human gut microbiota performs a variety of essential physiological homeostasis functions, including the development of the immune system, nutrient synthesis, vitamin production, and energy metabolism. Ginger's extensive pharmacological actions include anti-inflammatory, antioxidant, hypoglycemic, and lipid-lowering effects. This study aimed to investigate the beneficial effects of ginger on the prevention of obesity through the modulation of gut microbiota.</p><p><strong>Methods: </strong>This study was carried out as a systematic review in 2024 by searching on the reliable databases of PubMed, Web of Sciences, and Scopus using the keywords \"Obesity\", \"Gut-Microbiota\", \"Ginger\" and their MeSH were analyzed with no time limit. Articles published in English that specifically focused on the beneficial effects of ginger in the prevention of obesity through the modulation of gut microbiota were included. Abstracts, letters to the editor, protocols, review articles and studies were inaccessible were excluded from consideration. To assess the quality of the included studies, a tool comprising 10 items was developed.</p><p><strong>Findings: </strong>Generally, 3192 papers were retrieved from the above-mentioned databases and nine papers were considered for the present study after reading titles and abstracts and by considering the inclusion and exclusion criteria. In all these studies, the impact of ginger on gut microbiota has been examined, with a consistent focus on its effects on obesity. Overall, the existing evidence suggests that ginger not only positively influences gut microbiota but also serves as an effective agent in the prevention and management of obesity.</p><p><strong>Conclusion: </strong>These findings highlight the potential of ginger as a natural and effective option in obesity management programs and for improving overall health. Nonetheless, it is clear that the amount of ginger ingested may influence its effects, and more research is required to establish the proper dosage and understand the exact how ginger supplementation works.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"200"},"PeriodicalIF":2.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socio-demographic and attitudinal factors influencing household fruit and vegetable purchasing frequency in Eastern Türkiye.","authors":"Omer Yalvac, Nurhan Keskin, Mustafa Terin, Hanifeh Seyed Hajizadeh, Ozkan Kaya","doi":"10.1186/s41043-025-00955-7","DOIUrl":"10.1186/s41043-025-00955-7","url":null,"abstract":"<p><strong>Background: </strong>This study examines the relationship between households' fruit and vegetable purchasing frequency and their socio-demographic characteristics and attitudes, with a focus on Eastern Türkiye's Van province, a region underrepresented in existing literature.</p><p><strong>Objective: </strong>To explore how socio-demographic and attitudinal factors influence the frequency of household fruit and vegetable purchases.</p><p><strong>Methods: </strong>Methodologically, the research employs a Chi-square test of independence to compare households' fruit and vegetable purchasing frequencies across four categories: never, twice a month, once a week, and more than once a week. To further analyze the determinants of purchasing frequency, an ordered probit model was utilized. This econometric approach was applied to obtain coefficients used in calculating marginal effects and probabilities.</p><p><strong>Results: </strong>The empirical results reveal significant influences of various household characteristics on fruit and vegetable purchasing frequency. Household income, fruit and vegetable expenditure, employment and insurance status of the household head, perception of sufficient fruit and vegetable consumption within the household, and fruit and vegetable consumption by children in the household were found to positively affect the frequency of household fruit and vegetable purchases. Conversely, the age of the household head was found to negatively impact the frequency of fruit and vegetable purchases. Given the behavioral elements involved in food purchasing, this study also incorporates attitudinal and perceptual factors that may reflect bounded rationality beyond classical utility theory.</p><p><strong>Conclusion: </strong>This research contributes to both public health and behavioral economics literature by integrating socio-demographic and psychological variables into the analysis of purchasing behavior. The findings suggest that multifaceted approaches may be necessary to effectively increase fruit and vegetable consumption, including economic interventions, educational programs, and targeted interventions for specific demographic groups such as older adults. The results also offer empirical support for developing regionally tailored strategies in under-studied areas like Van.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"202"},"PeriodicalIF":2.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12168251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Areas of research focus and trends in the research on the application of AIGC in healthcare.","authors":"Chen Wang, Yingying Zhu, Xuejiao Zhang, Xueqing Chen, Yilin Li, Yongjie Tan, Huiying Qi","doi":"10.1186/s41043-025-00947-7","DOIUrl":"10.1186/s41043-025-00947-7","url":null,"abstract":"<p><strong>Background: </strong>As a crucial part of current AI technology, the extent of AIGC's (Artificial Intelligence Generated Content) impact on healthcare, its potential to further drive the development of intelligent healthcare, and its ability to alleviate the current scarcity of medical resources have become highly discussed topics in academia and the healthcare sector. Our aim is to conduct bibliometric study to analyze and visualize the current research hotspots and trends related to the application of AIGC in healthcare.</p><p><strong>Methods: </strong>Studies related to the application of AIGC in healthcare that were published from November 30 2022, to December 31 2023, were retrieved via the Web of Science Core Collection. CiteSpace and Microsoft Excel were utilized to analyze and visualize the annual publications, countries, institutions, authors, journals, high cited literature and keywords.</p><p><strong>Results: </strong>A total of 3411papers were included, and the number of publications is increasing rapidly in recent two years. The United States and Harvard University are respectively the leading country and institution in terms of the number of research publications on the application of AIGC in healthcare. Thongprayoon Charat and Cheungpasitporn Wisit are outstanding investigators in this field. Nature is the most influential journal in the field of AIGC' s application in healthcare, whereas Cureus Journal of Medical Science boasts the highest number of publications on this topic. The analysis of keywords and high cited literature has identified current research hotspots, including the impact exploration of the application of AIGC in the healthcare industry, the assessment of applicability, the perception of healthcare related personnel, and the development of AIGC in the healthcare field.</p><p><strong>Conclusions: </strong>This paper presents a bibliometric analysis of the research framework and hotspots concerning the application of AIGC in healthcare. The analysis aims to provide a comprehensive understanding of this field for researchers. Future research should focus on establishing regulatory mechanism, optimizing healthcare information services, clarifying the role of AIGC, and continuously developing medical large language models.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"195"},"PeriodicalIF":2.4,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}