Journal of Health, Population, and Nutrition最新文献

{"title":"Negative association between body roundness index and constipation: insights from NHANES.","authors":"Lingting Chen, Huirong Xiao, Xuchao Yu, Bingbin Huang, Sirong Guo, Ting Yuan, Siyang Deng","doi":"10.1186/s41043-025-00886-3","DOIUrl":"https://doi.org/10.1186/s41043-025-00886-3","url":null,"abstract":"<p><strong>Backgrounds: </strong>The relationship between body roundness index (BRI), a metric that distinguishes heterogeneity in fat distribution, and constipation is unclear. This study is the first to investigate the association between BRI and constipation based on the National Health and Nutrition Examination Survey (NHANES) in the United States, providing a new perspective on the mechanisms of obesity-related gastrointestinal dysfunction.</p><p><strong>Methods: </strong>This cross-sectional study utilized data from the NHANES conducted between 2005 and 2010. Constipation was diagnosed based on the Bristol Stool Form Scale (BSFS). Weighted logistic regression models were employed to assess the association between BRI and constipation prevalence. Restricted cubic splines (RCS) and piecewise linear regression models were applied to evaluate non-linear relationships between BRI and constipation. Propensity score matching (PSM) was implemented to match constipated and non-constipated populations with similar baseline characteristics. Subsequent analyses were conducted to investigate the correlation between BRI and constipation.</p><p><strong>Results: </strong>A total of 12,732 eligible participants were included. A negative correlation was observed between BRI and constipation prevalence, with an adjusted odds ratio (OR) of 0.87 (95% CI: 0.80, 0.95) after controlling for all covariates. When BRI was categorized into quartiles (Q1-Q4), both Q3 and Q4 groups exhibited significantly reduced constipation risk compared to Q1 (OR = 0.72, 95% CI: 0.54-0.97; OR = 0.63, 95% CI: 0.46-0.87). The RCS regression model revealed a linear inverse association between BRI and constipation risk (nonlinearity test P = 0.083). Subgroup analyses identified significant interaction effects of BRI with age, alcohol consumption status, and hypertension on constipation risk (interaction P < 0.05). Post PSM, constipation patients demonstrated higher BRI levels than non-constipation counterparts (P = 0.013).</p><p><strong>Conclusion: </strong>An inverse association was observed between BRI and constipation risk in U.S. adults, suggesting that lower BRI levels may correlate with raised constipation incidence. This underscores the critical importance of maintaining optimal BRI levels for constipation prevention. Further research is warranted to elucidate the underlying mechanisms governing this association.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"149"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triglyceride to high-density lipoprotein ratio as a predictor for 10-year cardiovascular disease in individuals with diabetes in Thailand.","authors":"Methavee Poochanasri, Sethapong Lertsakulbunlue, Chutawat Kookanok, Ram Rangsin, Wisit Kaewput, Mathirut Mungthin, Parinya Samakkarnthai","doi":"10.1186/s41043-025-00835-0","DOIUrl":"https://doi.org/10.1186/s41043-025-00835-0","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide. The triglyceride to high-density lipoprotein cholesterol (TG/HDL) ratio has emerged as a potential marker for CVD risk. However, its predictive value for high 10-year predicted Cardiovascular (CV) risk remains unclear; This study evaluates the predictive value of the TG/HDL-C ratio for 10-year cardiovascular risk using the Framingham Heart Study (FHS) risk prediction model in individuals with Type 2 Diabetes Mellitus (T2DM).</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 61,004 adults from 2014,2015, and 2018 aged 30-74 years with T2DM, without a history of CVD. The FHS model was used to estimate 10-year predicted CV risk, and high CVD risk was defined as ≥ 20%. ROC curve analysis was used to determine the optimal TG/HDL cutoff for high 10-year predicted CV risk in the overall population and age-specific subgroups. Logistic regression was performed to find the association between TG/HDL and high 10-year predicted CV risk, adjusting for potential confounders.</p><p><strong>Results: </strong>The optimal TG/HDL-C cutoff was 2.52 (AUC = 0.618, 95% CI: 0.612-0.624), with 67% sensitivity and 50% specificity. Higher TG/HDL were associated with increased odds of high predicted CVD risk in a dose-dependent manner, with an adjusted odds ratio (AOR) of 5.16 (95% CI: 4.86-5.49) in the highest TG/HDL quartile (> 4.91). Age-stratified analysis identified lower cutoffs for older adults (≥ 60 years: 2.42, AUC = 0.694) than younger individuals (< 60 years: 2.98, AUC = 0.636), indicating stronger predictive performance in older adults.</p><p><strong>Conclusions: </strong>The TG/HDL ratio is significantly associated with 10-year predicted CVD risk in T2DM with age-specific differences in predictive value. The lower cutoff for older adults (2.42) suggests even modest elevations indicate increased risk. These findings support TG/HDL integration into routine CVD risk assessments and highlight the importance of age-specific cutoffs for improved risk stratification.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"147"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fear of intimate partner and women's engagement in exercise: insights from a national survey in Kenya.","authors":"Joshua Okyere, Abigail Kabukie Dosoo, Castro Ayebeng, Precious Adade Duodo, Kwamena Sekyi Dickson","doi":"10.1186/s41043-025-00838-x","DOIUrl":"https://doi.org/10.1186/s41043-025-00838-x","url":null,"abstract":"<p><strong>Background: </strong>Women in abusive or controlling relationships often experience restrictions on their autonomy, mobility, and decision-making capacity. Furthermore, fear of a husband or partner, whether stemming from psychological abuse, coercive control, or physical violence, may influence a woman's ability to engage in health-promoting activities like exercise. However, the relationship between fear in intimate relationships and excercise remains underexplored. We examined whether there was an association between relational fear and women's engagement in exercise, as well as the direction of this association.</p><p><strong>Methods: </strong>We analyzed the data of 5,052 women (15-49 years) who participated in the 2022 Kenya Demographic and Health Survey. We derived the outcome variable from the question: \"how many days per week do you exercise?\" The responses were recoded as '0 = do not exercise' and '1/7 days = exercises'. All estimates were weighted. Cross-tabulations and two sets of binary logistic regression models were computed in STATA version 18. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Most women exercised three or more days per week (59.6%) while 22.9% did not exercise at all. Women who were most of the time afraid of their partner had a 47% higher likelihood of engaging in exercise compared to those who were never afraid (COR = 1.47, 95%CI: 1.16-1.88). After adjusting for confounders, this association weakened but remained significant (AOR = 1.33, 95%CI: 1.03-1.71). Similarly, women who were sometimes afraid of their partner showed significantly higher odds of engaging in exercise in both crude (COR = 1.30, 95%CI: 1.11-1.53) and adjusted models (AOR = 1.23, 95%CI: 1.04-1.46). Increasing age, higher education levels, rural residency and media exposure were strongly associated with increased exercise engagement.</p><p><strong>Conclusion: </strong>This study reveals a positive association between fear in intimate relationships and women's engagement in exercise, suggesting that exercise may serve as a coping mechanism for some women experiencing relational fear. While these results contribute to the limited literature on the intersection of intimate partner dynamics and preventive health behaviors, they remain preliminary. Further research is needed to explore the causal pathways, contextual influences, and potential long-term implications of relational fear on exercise engagement.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"150"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between insulin resistance and multiple chronic diseases: a cross-sectional study from CHARLS.","authors":"Wen-Ze Jiang, Zhen-Liang Fan, Meng-Li Xu, En-Hui Qian, Ke-Da Lu","doi":"10.1186/s41043-025-00878-3","DOIUrl":"https://doi.org/10.1186/s41043-025-00878-3","url":null,"abstract":"<p><strong>Background: </strong>Chronic disease is a global public health problem. This study aimed to explore the association between insulin resistance (IR)-related indices and various chronic diseases, and to evaluate the predictive capacity of IR-related indices for these diseases.</p><p><strong>Methods: </strong>The data used in this study came from CHARLS. Binary logistic regression analysis and RCS were used to analyze the relationship between IR-related indices, including TyG, TyG-BMI, TyG-WHtR, METS-IR and eGDR, with nine chronic diseases. Subgroup analysis was performed to test the stability of the results. Finally, the predictive power of IR-related indices for chronic diseases was tested by ROC curve.</p><p><strong>Results: </strong>A total of 8,177 participants were included in this study. The study found that elevated prevalence of multiple chronic diseases is positively associated with increases in TyG, TyG-BMI, TyG-WHtR, and METS-IR, and negatively associated with eGDR. ROC analysis revealed that IR-related indices had the best accuracy in predicting dyslipidemia compared to other diseases, with TyG being the best predictor.</p><p><strong>Conclusions: </strong>IR-related indices were positively associated with the prevalence of multiple chronic diseases. The burden of chronic diseases can be reduced by improving IR in middle-aged and older people.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"148"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of antenatal care on low birth weight and neonatal mortality: protocol for umbrella review of meta-analysis.","authors":"Fentahun Alemnew Chekole, Azimeraw Arega Tesfu, Fentahun Yenealem Beyene, Wondu Feyisa Balcha","doi":"10.1186/s41043-025-00904-4","DOIUrl":"https://doi.org/10.1186/s41043-025-00904-4","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization defines low birth weight as a birth weight of less than 2500 g, regardless of the gestational age. It is regarded as the most significant predictor of infant mortality overall, particularly for deaths that occur in the first few months of life. Among all the months of a person's existence, the neonatal period, the first month of life, has one of the highest death rates. The necessity for an umbrella review is highlighted by the lack of a comprehensive synthesis of collective meta-analytic evidence connecting antenatal care as a factor of low birth weight and newborn death. Thus, this umbrella review's main goal is to thoroughly synthesize the existing meta-analytic evidence, with a focus on assessing the relationship between antenatal care with low birth weight and neonatal mortality.</p><p><strong>Methods: </strong>All English-language meta-analyses of cohort, case-control, and cross-sectional studies that looked at the relationship between antenatal care with low birth weight and neonatal mortality will be included, regardless of the time and location of publication. To find pertinent literature for review, major medical electronic databases including Embase, CINAHL, Cochrane database, and PubMed will be used. Two reviewers will screen the eligible articles, extract data, and evaluate their quality independently. The reviewers will work together to reach a consensus on any disagreements. If there are still issues, a third reviewer will be consulted in order to fix them. The meta-umbrella R package will be used for all statistical analysis. The random-effects model and 95% prediction interval for the summary estimate will be used for both outcomes. Q and I² test statistics will be calculated to determine the degree of heterogeneity. We will use Egger's regression asymmetry test to assess publication bias, the Ioannidis test for excess significance bias, and Hedges' g value for each risk factor.</p><p><strong>Discussion: </strong>This is the first comprehensive analysis of the effect of antenatal care on low birth weight and neonatal mortality that we are aware of. For clinicians and researchers seeking to lower low birth weight and neonatal mortality, summarizing this evidence is helpful.</p><p><strong>Trial registration: </strong>PROSPERO-CRD42024567150.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"146"},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological and psychological effects of visits to different linear Spatial landscape on the students: a field experiment in the campus environment.","authors":"Ren-Lin Zhao, Lu-Qi Bai, Yu-Lin Zhao, Yi-Tian Zhou, Meng Luo","doi":"10.1186/s41043-025-00903-5","DOIUrl":"https://doi.org/10.1186/s41043-025-00903-5","url":null,"abstract":"<p><strong>Background: </strong>There is now a substantial body of evidence supporting the positive impact of urban green spaces on human health and well-being. Most studies in this field have primarily focused on various types of green landscapes. However, there remains a notable gap in research regarding specific green spaces, particularly those associated with linear spatial landscapes, such as pathway spaces. The purpose of this study is to explore the restorative effects of the different types of linear spaces within the campus environments on the students' physical and mental health.</p><p><strong>Methods: </strong>We investigated psycho-physiological responses of the participants in each group (N = 40, 20 ± 2.4 years old) to the environments of pre- and post-visiting the different pathway spaces, including avenue passage space (APS), gallery frame passage space (GPS), waterfront road passage space (WPS), driveway passage space (DPS), and indoor corridor passage space (IPS) (Control group). Physiological factors were examined using heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and psychological evaluation was carried out using the Profile of Mood States (POMS), State-Trait Anxiety Inventory (STAI), and the Perceived Restorative Scale (PRS).</p><p><strong>Results: </strong>The results indicated that SBP, DBP, and HR levels of participants were significantly reduced after visiting APS, FPS, and WPS, whereas remarkable increases in HR were observed in the DPS. The POMS scores for anger-hostility (A-H), fatigue-inertia (F-I), tension-anxiety (T-A), confusion-bewilderment (C-B), and depression-dejection (D-D) were significantly lower, but vigor-activity (V-A) was higher post-visiting than pre-visiting. Furthermore, the participants exhibited significantly reduced anxiety levels and high psychological restoration levels, as indicated by the STAI and PRS. Importantly, the most pronounced changes in measurement indices were observed in the GPS.</p><p><strong>Conclusions: </strong>Our study demonstrates that exposure to linear spatial landscapes, particularly those featuring abundant landscape elements, safety features, and shelter, such as GPS, holds potential as a therapeutic method for improving physiological functions and as an effective psychological relaxation strategy for students in campus environments.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"145"},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"African immigrants' health behaviors related to non-communicable diseases- a qualitative systematic review.","authors":"Emmaculate Tamankag, Tiina Valkendorff, Riikka Lämsä","doi":"10.1186/s41043-025-00854-x","DOIUrl":"https://doi.org/10.1186/s41043-025-00854-x","url":null,"abstract":"<p><strong>Background: </strong>Non-communicable diseases (NCDs) are on the rise globally, accounting for approximately 71% of deaths worldwide. This upward trend has also been observed among the increasing population of African immigrants residing in Western countries, where health behavior and various sociocultural and socioeconomic factors contribute to the growing prevalence of NCDs in this group.</p><p><strong>Aim: </strong>This study explored the health behaviors of African immigrants related to NCDs, and the sociocultural and socioeconomic factors influencing these behaviors. The aim is to provide evidence-based insight that can be used in the development of culturally sensitive interventions in the prevention of NCDs among African immigrants in Western countries.</p><p><strong>Method: </strong>A comprehensive search of relevant literature was done to identify relevant articles using three databases (MEDLINE, CINAHL, and SCOPUS) between 2022-2024. The systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Based on the inclusion and exclusion criteria, 11 studies were included in the final synthesis.</p><p><strong>Results: </strong>The findings showed that African immigrants retain both positive and negative health behaviors after migration, while also adopting certain behaviors from their host countries that heighten their risk of developing NCDs. Additionally, socioeconomic status before and after migration, as well as sociocultural values, were found to have a negative influence on their health behaviors. Gender-specific factors also contributed to shaping these behaviors.</p><p><strong>Conclusion: </strong>Considering the changing environment African immigrants encounter in their host countries, it is essential to account for the unique characteristics of this growing group when designing culturally sensitive health interventions aimed at preventing NCDs.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"144"},"PeriodicalIF":2.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management.","authors":"Aya A Muhammed Saeed, Sobia Noreen, Farhang H Awlqadr, Muhammad Irshad Farooq, Maria Qadeer, Nadia Rai, Halgurd Ali Farag, Mohammed N Saeed","doi":"10.1186/s41043-025-00899-y","DOIUrl":"https://doi.org/10.1186/s41043-025-00899-y","url":null,"abstract":"<p><p>Polycystic Ovary Syndrome (PCOS) is a common health condition related to a woman's hormonal problems. Hormonal imbalance, metabolic disorders, and an increased insulin level mainly characterize the ailment. This detailed review focuses on dietary strategies, macromolecules, macromolecules, and herbal interventions that exception-ally work in PCOS treatment. Research has shown that Mediterranean, low-glycemic index, and ketogenic diets that are modified with individuals in mind are the best ways to resolve insulin resistance, obesity, and lack of ovulation. The other nutrients shown to affect glucose metabolism and play a role in hormone regulation are the macromolecules, such as increased protein and reduced refined carbs. Among the different micronutrients, vitamin D, omega-3 fatty acids, and inositol were shown to be the most vital supplements in the treatment of PCOS-induced oxidative damage, hyperandrogenism, and infertility. Not to mention, cinnamon, curcumin, sage, fennel, and traditional Chinese herbal medicine are among some of the herbal remedies that so far show good potential to be the perfect complementary therapy tools as they create better glycemic control, inflammation reduction, and menstrual cycle regularization. Even though the findings are promising, the current supply of clinical trials for standardizing these nutritional and herbal protocols is lacking. Overall, this report stresses the fact that a customized, holistic diet regime is the best treatment for women with PCOS to make them feel well and live a long and healthy life.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"143"},"PeriodicalIF":2.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between dietary acid load and risk of gallstone: a case-control study.","authors":"Zohreh Khosravani Shooli, Danial Fotros, Azita Hekmatdoost, Moloud Ghorbani, Amir Sadeghi, Zahra Yari","doi":"10.1186/s41043-025-00894-3","DOIUrl":"https://doi.org/10.1186/s41043-025-00894-3","url":null,"abstract":"<p><strong>Background and aim: </strong>While dietary factors are known to influence gallstone disease (GD), the specific role of dietary acid load (DAL) remains unclear. This study aimed to explore the relationship between DAL and GD risk using a case-control design.</p><p><strong>Methods: </strong>The study included 189 adults with newly diagnosed GD and 342 controls. Anthropometric data were collected, and DAL was calculated using the potential renal acid load (PRAL) and net endogenous acid production (NEAP) indices. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI), adjusting for confounders.</p><p><strong>Results: </strong>Participants in the higher tertiles of both PRAL and NEAP scores showed notably elevated grain consumption and reduced intake of vegetables and fruits (P < 0.001). Conversely, an inverse relationship was observed between NEAP scores and intake of legumes, nuts, and seeds (P = 0.044). After adjustment for confounders, the risk of GD was 25% higher in the second tertile (OR: 1.25; 95% CI: 0.9, 2.3) and 51% higher in the third tertile (OR: 1.51; 95% CI: 0.54, 1.36) of PRAL compared to the first tertile (P trend = 0.023). A similar trend was seen for NEAP, with a 19% increased risk in the second tertile (OR: 1.19; 95% CI: 0.78, 1.84) and 48% in the third tertile (OR: 1.48; 95% CI: 0.9, 2.3) relative to the first tertile.</p><p><strong>Conclusions: </strong>Higher dietary acid load is associated with an increased risk of GD. Further studies are needed to confirm these findings and elucidate underlying mechanisms.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"141"},"PeriodicalIF":2.4,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research trajectory of the mechanism of preeclampsia: a scientometric perspective.","authors":"Shen Li, Meiling Sun, Datong Liu, Xuanyi Wang","doi":"10.1186/s41043-025-00806-5","DOIUrl":"https://doi.org/10.1186/s41043-025-00806-5","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to conduct a scientometric analysis on the research history and emerging trends of the pathogenesis of preeclampsia using CiteSpace and VOSviewer software. The goal is to provide guidance for future research and clinical practice.</p><p><strong>Methods: </strong>The core collection database of Web of Science was searched for research literature on the mechanism of preeclampsia from January 1980 to March 2024. CiteSpace6. 1. R6, 5. 7. R5 (64-bit), and VOSviewer1.6.19 software were used for visual analysis, including networks of keywords, countries, authors, institutions, funds, and fields.</p><p><strong>Results: </strong>A total of 4989 documents were analyzed in this study. The number of published articles has shown a consistent increase from 1990 to 2022, indicating that this topic remains a significant area of research. The countries, institutions, authors, journals, and fields that contributed the most articles include the USA, University of Mississippi, Lamarca, Babbette, Placenta, and the field of OBSTETRICS and GYNECOLOGY. Keyword clustering and emergence analysis identified 7 clusters, while clustering and emergence analysis of cited documents identified 14 clusters. These analyses revealed that current research on the mechanism of preeclampsia primarily focuses on placental ischemia and hypoxia, inflammatory response and immune disorders, angiogenic factor imbalance, abnormal epigenetic modifications, and intestinal flora imbalance.</p><p><strong>Conclusions: </strong>Research on the mechanisms of preeclampsia is rapidly advancing. Given the presence of multiple mechanisms and pathways, further collaborative research is essential to guide clinical treatment effectively and enhance maternal and child outcomes.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"142"},"PeriodicalIF":2.4,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}