Journal of Health, Population, and Nutrition最新文献

{"title":"Short-term effects of air pollutants on hospitalization for childhood respiratory diseases in Suzhou City: a time-stratified case-crossover study.","authors":"Ruoqi Zhang, Jiawei Chen, Mengru Wang, Zhengrong Chen, Hongpeng Sun","doi":"10.1186/s41043-024-00683-4","DOIUrl":"10.1186/s41043-024-00683-4","url":null,"abstract":"<p><strong>Background: </strong>Short-term exposure to air pollution has been demonstrated in previous studies to correlate with respiratory disease (RD) in children. Due to regional heterogeneity, our objective was to explore the correlation between short-term exposure to ambient air pollution and hospital admissions for respiratory ailments in children in Suzhou City from January 1, 2017, to December 31, 2022, alongside assessing the influence of the COVID-19 pandemic on this relationship.</p><p><strong>Methods: </strong>We collected data on air pollutant levels and hospital admissions for childhood respiratory disease (RD) in Suzhou, China, from 2017 to 2022. We utilized a time-stratified case-crossover design along with a conditional logistic regression model to assess the short-term impacts of air pollutants on RD in children through stratified analysis and sensitivity analysis.</p><p><strong>Results: </strong>A total of 13,408 children with respiratory diseases were included in the study. The findings revealed significant associations between hospitalization for respiratory diseases in children and exposure to PM_2.5, PM₁₀, SO₂, NO₂, and CO. The maximum effect values (95%CI, best lag days) for each 10 µg/m³ increase in the concentrations of PM_2.5, PM₁₀, SO₂, and NO₂ were as follows: 1.017 (1.003-1.031, lag0-2), 1.015 (1.004-1.026, lag0-2), 1.117 (1.001-1.247, lag0-1), and 1.036 (1.009-1.064, lag0-7). Additionally, the maximum effect value (95%CI, best lag days) for each 1 mg/m³ increase in CO concentration was found to be 1.267 1.017-1.579, lag0-7). Stratified analysis indicated that sex, season of admission, and stage of admission did not modify these correlations significantly; however, differential effects on various age groups and sexes were primarily observed among school-age and older children as well as boys.</p><p><strong>Conclusions: </strong>The short-term exposure to PM_2.5, PM₁₀, SO₂, NO₂, and CO in Suzhou, China, exhibited a positive correlation with RD hospitalization. Prior to the COVID-19 pandemic, the adverse impacts of air pollutants on hospitalizations for childhood respiratory disease were mitigated compared to the period following the pandemic. Local governments should continue promoting decisions and measures for air pollution prevention and control to reduce further pollutant concentration, which is crucial for public health in reducing the burden of childhood respiratory diseases.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"208"},"PeriodicalIF":2.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note To: Nutrition self-efficacy assessment: designing and psychometric evaluation in a community-dwelling elderly population.","authors":"Abbas Shamsalinia, Reza Ghadimi, Razieh Torabi Chafjiri, Faezeh Norouzinejad, Ali Pourhabib, Fatemeh Ghaffari","doi":"10.1186/s41043-024-00705-1","DOIUrl":"10.1186/s41043-024-00705-1","url":null,"abstract":"","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"207"},"PeriodicalIF":2.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum vitamin D concentration and anthropometric indicators of adiposity in adults without or with low dose statin users: a cross-sectional study.","authors":"Haleh Ashraf, Nastaran Maghbouli, Maryam Abolhasani, Nadia Zandi, Mehran Nematizadeh, Negar Omidi, Gholamreza Davoodi, Mohammad Ali Boroumand, Jemal Haidar Ali","doi":"10.1186/s41043-024-00668-3","DOIUrl":"10.1186/s41043-024-00668-3","url":null,"abstract":"<p><strong>Background: </strong>This study sought to determine the accuracy of several anthropometric parameters in association with serum Vit. D concentrations and to compare the novel indices with the conventional ones.</p><p><strong>Methods: </strong>A total of 947 individuals referred to the cardiology clinic who have not used statin or take low-dose statin were evaluated through a cross-sectional study. Data on demographic information, anthropometric indices, and biochemical measurements were gathered using a checklist. Both the multivariable regression modeling and the area under the receiver-operating characteristic (ROC) were employed for the analysis.</p><p><strong>Results: </strong>Considering novel indices, BRI (Body Roundness Index) showed the most powerful correlation with serum Vit. D levels among both genders. Among conventional ancient indices, WC (Waist Circumference) had the strongest association in both men and women groups. Based on the confounding factors-adjusted model, the highest odds ratio (OR) for the presence of Vit. D deficiency belonged to WHtR (Waist to Height Ratio) in women (OR, 0.347 (0.171-0.704), P = 0.003). None of the indices predicted Vit. D deficiency significantly among men. A Vit. D concentration of 4.55 ng/ml was found as a cutoff based on the metabolic syndrome status.</p><p><strong>Conclusion: </strong>The most powerful association with serum Vit. D levels were detected for BRI in both genders among newly developed indices. In addition, WHtR predicted Vit. D deficiency independent of confounding factors among women.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"206"},"PeriodicalIF":2.4,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Edible mushrooms as an alternative to animal proteins for having a more sustainable diet: a review.","authors":"Kimia Haji Ali Pashaei, Kiyavash Irankhah, Zahra Namkhah, Seyyed Reza Sobhani","doi":"10.1186/s41043-024-00701-5","DOIUrl":"10.1186/s41043-024-00701-5","url":null,"abstract":"<p><strong>Background: </strong>High protein sources especially animal protein is being used widely in people's diet. Ensuring a healthy and sustainable diet should be a global priority. Compared to diets rich in animal products, plant-based diets are more sustainable because they have less environmental impact. Aim of this article is to review mushroom's sustainability.</p><p><strong>Main body: </strong>Using meat analogues like mushrooms seems to be a good option because their taste and texture are alike meat and they are sustainable healthy foods as they are good environmental choice due to their less water and land footprint but they are not a cost-benefit food.</p><p><strong>Conclusion: </strong>Mushroom is a good nutritional and environmental meat substitute as it has less water and land footprint but not as a cost-benefit meat alternative. Therefore, the governments should make policies to use mushroom as an economical meat alternative and a source of protein for all consumers.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"205"},"PeriodicalIF":2.4,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of Baduanjin exercise on the psychological condition and heart rate variability of sports-disadvantaged college students: A randomised trial.","authors":"Zhiping Wang, Zhaoxiang Zhang, Yingqing Wu","doi":"10.1186/s41043-024-00691-4","DOIUrl":"10.1186/s41043-024-00691-4","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of a 16-week Baduanjin exercise programme on the psychological status and heart rate variability (HRV) of college students in a sports-disadvantaged group, offering a theoretical basis for the potential of Baduanjin exercise to improve mental health.</p><p><strong>Trial design: </strong>This prospective study enrolled 93 college students from Wuyi University, exempt from the National Standards for Students' Physical Health due to illness or disability. The participants were divided into a control group (n = 47) and an experimental group (n = 46). Over 16 weeks, the experimental group engaged in the Baduanjin exercise, whereas the control group did not participate in regular physical training.</p><p><strong>Methods: </strong>We assessed the Symptom Checklist-90-Revised (SCL-90-R, the primary outcome) scores and HRV (time domain and frequency domain indices, the secondary outcomes) of all participants both before and after the 16-week programme.</p><p><strong>Results: </strong>(1) Post-16 weeks of Baduanjin exercise, a statistically significant difference was observed in the SCL-90-R scores between the control and experimental groups (P < 0.01, P < 0.05). Notably, the scores for interpersonal sensitivity, depression, anxiety, psychoticism, and other factors (predominantly relating to sleep and diet) were significantly lower in the experimental group (t = 4.234, 2.616, 3.450, 2.226, 3.980, P < 0.01, P < 0.05). (2) Following the exercise regimen, the experimental group showed a substantial decrease in heart rate, low-frequency (LF) power, and the LF/high-frequency ratio (LF/HF ratio), and a significant increase in HF compared with the control group (t = 2.358, 4.528, - 2.595, P < 0.05 P < 0.01).</p><p><strong>Conclusion: </strong>Sixteen weeks of Baduanjin exercise may substantially enhance HRV, potentially aiding in balancing sympathetic-vagal nerve activity and thus contributing to the regulation of mental health.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"203"},"PeriodicalIF":2.4,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and hotspots in research on osteoporosis and nutrition from 2004 to 2024: a bibliometric analysis.","authors":"Min Li, Binyang Yu, Haiyan Yang, Haiyan He, Ning Li, Aili Lv, Xiaoling Zhou, Rui Gao","doi":"10.1186/s41043-024-00690-5","DOIUrl":"10.1186/s41043-024-00690-5","url":null,"abstract":"<p><strong>Background: </strong>The intricate association between nutrition and osteoporosis has garnered increasing attention, and approximately 3000 articles have been published in the past 20 years. However, there are currently very few comprehensive reviews on the development of this field. It is very necessary to retrospectively analyze the related articles and summarize the research hotspots, depth, and directions.</p><p><strong>Objectives: </strong>This study aimed to quantitatively analyze, visually review and comment on the articles published in the field of osteoporosis and nutrition based on the bibliometric methods, providing new insights for future research.</p><p><strong>Methods: </strong>The related articles published from 2004 to 2024 were retrieved from the Web of Science Core Collection (WOSCC). CiteSpace 6.1R2 software was used to conduct collaborative network analysis of annual publication volume, author patterns, country/region contributions, institutional affiliations, journal publications, highly cited literature, and keyword clustering.</p><p><strong>Results: </strong>A total of 2138 articles were assessed, revealing a consistent upward trend in published works in this domain, with the majority originating from the United States (564 papers). Seoul National University was identified as the most prolific institution (56 papers). Geng Bin was the most prolific author. Research hotspots included bone density, postmenopausal women, vitamin D, hip fractures, etc. Research subjects included physical activity, sarcopenia, calcium intake, machine learning, etc. Recent research trends indicate that cross-sectional study was more and the quality of life, muscle, and zinc are receiving attention in studies.</p><p><strong>Conclusions: </strong>Future research should continue to explore better methods for measuring bone density, investigating indicators for predicting fracture risk, exploring the relationship between various nutrients and substances with osteoporosis at a deeper level, and bolstering management strategies for male osteoporosis. Researchers should conduct longitudinal or interventional studies, and further improving the overall quality of life of patients with osteoporosis.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"204"},"PeriodicalIF":2.4,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An epidemiological investigation of the prevalence of digestive diseases in the older prisoner population in Taiwan.","authors":"Zhu Liduzi Jiesisibieke, Ping Tao, Yen-Chun Wang, Ching-Wen Chien, Tao-Hsin Tung","doi":"10.1186/s41043-024-00693-2","DOIUrl":"https://doi.org/10.1186/s41043-024-00693-2","url":null,"abstract":"<p><strong>Objective: </strong>The prison population has been increasing globally, and prisoner health is an important issue of global health. However, it has not received sufficient attention, especially in developing countries and regions. Among all the prisoners, the health status of older prisoners requires special attention due to their declining health and energy. This study aims to assess the prevalence of digestive diseases among older prisoners in Taiwan.</p><p><strong>Methods: </strong>Data on older prisoners from the National Health Insurance Research Database from January 1 to December 31, 2013, were used in this study. Digestive diseases were assessed in 2,215 older prisoners using the International Classification of Diseases, 9th revision Clinical Modification (ICD-9-CM). We identified the most common digestive diseases and explored any sex-specific differences in their prevalence.</p><p><strong>Results: </strong>The estimated prevalence of digestive system diseases among the prisoners was 51.56%. Older women prisoners had a higher prevalence (62.68%) compared to men prisoners in general (50.80%). Diseases with a prevalence > 10% include esophageal, gastric, and duodenal diseases; diseases of the oral cavity, salivary glands, and jaws; and other intestinal and peritoneal diseases. Women prisoners showed a significantly higher prevalence of diseases of the oral cavity, salivary glands, jaws, esophagus, stomach, duodenum, non-infectious enteritis, and colitis.</p><p><strong>Conclusion: </strong>Our findings indicate that a considerable number of older prisoners in Taiwan experienced digestive diseases, which may be attributable to general deterioration of physical function and poor resistance. Early detection and treatment are crucial for these conditions, and it is important to maintain human rights and justice in prison systems.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"202"},"PeriodicalIF":2.4,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of type 2 diabetes mellitus in persons living with HIV initiated on dolutegravir-based antiretroviral regimen in Ghana: an observational longitudinal study.","authors":"Margaret Lartey, Ernest Kenu, Vincent Ganu, Stephen Ayisi Addo, Kofi Agyabeng, Delia Bandoh, Marijanatu Abdulai, Prince Tsekpetse, Kwasi Torpey","doi":"10.1186/s41043-024-00695-0","DOIUrl":"10.1186/s41043-024-00695-0","url":null,"abstract":"<p><strong>Background: </strong>Few studies have reported hyperglycemia and diabetic ketoacidosis in patients on dolutegravir (DTG) treatment. This study determined the effect of DTG on fasting blood glucose levels in a cohort of persons living with HIV (PLHIV) in Ghana and initiating DTG regimens.</p><p><strong>Methods: </strong>A two-year observational longitudinal cohort study conducted from 12th October 2020 to 31st December 2022. Fasting blood glucose was measured at baseline, 12, 24, 36 and 72 weeks for patients after a 12 h overnight fast. The Kaplan-Meier estimator was used to estimate the risk of developing type 2 diabetes mellitus (T2DM). Cox proportional hazard model was used in estimating hazard ratios.</p><p><strong>Results: </strong>A total of 1334 non-diabetic patients were enrolled with 78% (1039) females and 83% (1104) were antiretroviral therapy experienced. The incidence proportion and rate of T2DM at 72 weeks were 11.8% (95%CI: 10.2-13.7) and 98.1 cases per 1000 PY (95%CI: 83.9-114.6) respectively. The median time to development of T2DM was 24 weeks post DTG initiation. Male sex (aHR 2.9 [95%CI: 1.9-4.3]), abnormal waist-hip ratio (1.67 [95% CI: 1.15-2.43]) and abnormal total serum cholesterol (aHR 1.6 [95%CI: 1.1-2.3]) were found to be significant determinants of T2DM.</p><p><strong>Conclusion: </strong>Incidence of T2DM is high among non-diabetic PLHIV within 72 weeks of initiating DTG based therapy with males having a higher risk. Longitudinal changes in waist-hip ratio and serum cholesterol among patients initiated on DTG needs to be monitored regularly.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"199"},"PeriodicalIF":2.4,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of inadequate HIV knowledge and its associated factors among the Malaysia general population: findings from the National Health and Morbidity Survey (NHMS) 2020.","authors":"Muhammad Azri Adam Adnan, Norhafizah Sahril, Mohamad Aznuddin Abd Razak, Norliza Shamsuddin, Mohd Hazrin Hasim Hashim, Mohd Hatta Abdul Mutalip","doi":"10.1186/s41043-024-00689-y","DOIUrl":"10.1186/s41043-024-00689-y","url":null,"abstract":"<p><strong>Background: </strong>Inadequate knowledge of human immunodeficiency virus (HIV) is underscored as a key factor contributing to the HIV epidemic. Nonetheless, current data on HIV knowledge in Malaysia are still scarce. Therefore, this study aimed to assess the prevalence of inadequate HIV knowledge and its associated factors among the general Malaysian population.</p><p><strong>Method: </strong>The study utilized data from the National Health and Morbidity Survey (NHMS) 2020, a nationwide cross-sectional survey employing a two-stage stratified random sampling technique to ensure national representativeness. HIV knowledge was assessed using the UNGASS indicators questionnaire, which comprises five questions on HIV prevention and transmission. The data were collected using the computer assisted telephone interviewing (CATI) method. Respondents who did not correctly answer all five questions were considered to have inadequate knowledge about HIV. Descriptive analysis and complex sample logistic regression were performed using SPSS version 28.0.</p><p><strong>Results: </strong>The survey identified 5,561 eligible respondents, leading to the participation of 3,187 individuals in the second phase of the study, which resulted in a response rate of 57.3%. Our study revealed an overall prevalence of inadequate HIV knowledge at 77.4%, with adolescents aged 13-19 exhibiting the highest prevalence at 86.1%. Multiple logistic regression analysis indicated that respondents with no formal education (aOR 4.34, 95% CI: 0.65, 29.08) were over four times more likely to lack HIV knowledge. Additionally, respondents with only secondary education had an increased risk of 1.79 times. Individuals residing in rural areas were significantly more likely to have inadequate HIV-related knowledge. Furthermore, respondents who worked as unpaid workers, homemakers, or caregivers (aOR 1.71, 95% CI: 1.05, 2.82) showed a higher likelihood of lacking HIV knowledge.</p><p><strong>Conclusion: </strong>Three out of four individuals in the general Malaysian population were found to lack sufficient knowledge about HIV. This underscores the need for targeted interventions in HIV education, particularly in rural areas and among populations with lower educational attainment. Additionally, digital platforms and youth-focused campaigns could be especially effective for reaching adolescents. Policymakers must prioritize inclusive, accessible HIV prevention strategies to address these gaps and reduce transmission rates.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"200"},"PeriodicalIF":2.4,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of low-fat diet on the levels of insulin-like growth factor-1 and insulin-like growth factor binding proteins: a systematic review and meta-analysis of randomized controlled clinical trials.","authors":"Zohreh Sadat Sangsefidi, Sepideh Soltani, Fatemeh Meshkini, Kimia Torabynasab, Sheida Zeraattalab-Motlagh, Elham Razmpoosh, Mahdi Hejazi, Masoumeh Khalighi Sikaroudi, Shima Abdollahi","doi":"10.1186/s41043-024-00698-x","DOIUrl":"10.1186/s41043-024-00698-x","url":null,"abstract":"<p><strong>Background: </strong>Previous researches on the effect of low-fat diet (LF) on insulin-like growth factor-1 (IGF-1), and its binding proteins (IGFBPs) did not reach a consensus result, and there is no study summarizing these findings. Thus, this systematic review and meta-analysis of randomized control trials (RCTs) was performed to pool available evidence and answer the question whether dietary fat can affect IGF-1 and IGFBPs or not.</p><p><strong>Methods: </strong>PubMed, Scopus, ISI Web of Science, Google, Google scholar, ProQuest, and the Cochrane Library were searched without language restrictions until July 2, 2024 to retrieve related studies. Weighted mean difference and the corresponding variance were considered as the effect size. Standard tools were applied to assess the quality of the studies and evidence.</p><p><strong>Results: </strong>Pooling data of the eligible studies showed no significant effect of LF diet on IGF-1 (six studies; participants = 1029.; pooled mean = 1.63 ng/ml, 95% CI= [-1.34, 4.59], P = 0.28, I² = 0.00%), and IGFBP-3 (five studies; participants = 969; pooled mean = 65.24 ng/ml, 95% CI= [-169.53, 300.00], P = 0.59, I² = 0.0%). The results of subgroup analysis for IGF-1 and IGFBP-3 also demonstrated no significant findings. For IGFBP-1, available evidence is insufficient since only two studies have been performed yet and their results are contradictory.</p><p><strong>Conclusions: </strong>This study indicated no significant effect of LF diet on IGF-1, and IGFBP-3 concentrations. Low certainty of evidence indicates that available evidence cannot support to draw a firm conclusion and future researches may change the estimates.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"43 1","pages":"201"},"PeriodicalIF":2.4,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}