Journal of Health, Population, and Nutrition最新文献

{"title":"Pooled prevalence of modern contraceptive utilization and its associated factors among reproductive age women in East Africa: derived from demographic and health surveys.","authors":"Gosa Mankelkl, Beletu Kinfe","doi":"10.1186/s41043-025-01019-6","DOIUrl":"10.1186/s41043-025-01019-6","url":null,"abstract":"<p><p>One of the most significant global public health concerns for women of reproductive age is the unmet need for modern contraceptives. The goal of increasing the use of modern contraceptives is to lower mother and child mortality and morbidity. Since East African nations are part of sub-Saharan Africa, a region primarily composed of low-income countries, they face significant challenges in accessing modern contraceptives due to limited healthcare infrastructure, economic constraints, and socio-cultural barriers. The objective of this study was to investigate the prevalence and factors associated with modern contraception utilization among reproductive-age East African women.</p><p><strong>Methods: </strong>The data was taken from the individual records (IR) of the ten East African countries' Demographic and Health Surveys. The study included 112,810 women of reproductive age. The primary outcome was modern contraceptive utilization, defined as a binary variable (yes = use of modern methods; no = use of traditional/folkloric or no methods). Key predictors included age, place of residence, marital status, sex of household head, wealth index, exposure to media (newspaper, radio, television), pregnancy termination history, and number of living children. Bivariate analysis was utilized to select the variables for multivariable analysis. At last, 95% CIs for the odds ratio and percentage were presented.</p><p><strong>Results: </strong>Among women of reproductive age, 33.81% of them used modern contraceptives, with a 95% CI of [33.53-34.09]. Individuals aged 20-24, 25-29, 30-34, and 35-39 demonstrate the following statistically adjusted odds ratios (AOR) and confidence intervals (CI): AOR = 1.68, 95% CI (1.68, 1.79); P = 0.0001; AOR = 1.56, 95% CI (1.46, 2.65); P = 0.0001; AOR = 1.43, 95% CI (1.33, 1.54); P = 0.0001; and AOR = 1.34, 95% CI (1.24, 1.44); P = 0.0001, respectively. urban residence is associated with an AOR of 1.06, 95% CI (0.91, 0.97); P = 0.001; being married [AOR: 1.20, 95% CI (1.13, 1.28); P = 0.0001]; belonging to the highest wealth quantile [AOR: 1.34, 95% CI (1.27, 1.43); P = 0.0001]; reading magazines at least once a week [AOR: 1.07 (1.00, 1.14); P = 0.032]; listening to the radio almost daily [AOR: 1.91 (1.69, 2.17); P = 0.0001]; watching television daily [AOR: 1.62 (1.45, 1.82); P = 0.0001]; and having 3-4 children [AOR: 11.68, 95% CI (10.78, 12.66); P = 0.0001] were found positively associated with modern contraceptive utilization. Conversely, having a history of pregnancy termination [AOR: 0.83 (0.80, 0.87); P = 0.0001] and belonging to a household headed by a woman [AOR: 0.95 (0.92, 0.99); P = 0.037] were found to be inversely associated with modern contraceptive utilization.</p><p><strong>Conclusion and recommendation: </strong>This study identified key factors influencing modern contraceptive use among women in East Africa. Higher utilization was associated with being aged 20-39, urban residence, being married, higher wea","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"261"},"PeriodicalIF":2.4,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taxing mechanisms on salty foods: investigation of effectiveness through price elasticity and cross price elasticity of demand.","authors":"Vahid Yazdi-Feyzabadi, Mohammad Hajizadeh, Enayatollah Homaie Rad, Anita Reihanian, Ali Hussein Samadi, Marjan Mahdaviroshan","doi":"10.1186/s41043-025-00951-x","DOIUrl":"10.1186/s41043-025-00951-x","url":null,"abstract":"<p><strong>Background: </strong>Salt consumption control strategies can help to decrease hypertension and related cardiovascular diseases. Taxation mechanisms help to reduce the utilization of harmful commodities like salts. This study aims to analyze the impact of taxing salty foods on salt intake in Iran by examining the price elasticity of demand (PED) and cross-price elasticity of demand (XED) for salty foods.</p><p><strong>Methods: </strong>This study used 38,328 household-level data from the 2019 Iranian Household Income and Expenditures Survey. This PED and XED for salty foods were calculated, and changes in household salt consumption due to salt taxation were estimated using a mathematical simulation method.</p><p><strong>Results: </strong>The findings revealed that the PEDs for noodles and pilaffs (- 4.89) and bread (- 2.03) are higher than that for other commodities. Noodles and salt (- 4.55) and breads and salt (- 1.61) exhibited the highest XED. Following 20% taxation, total salt intake is projected to increase by approximately 125 g per month.</p><p><strong>Conclusion: </strong>Taxing mechanisms are ineffective in reducing the consumption of salty foods. Instead of reducing salt intake, households tend to shift to lower-quality, cheaper salty foods after the tax are implemented. However, these mechanisms can be used for increasing the government revenue.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"259"},"PeriodicalIF":2.4,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of behavioural modification for small portions size consumption on BMI in college students of North India: a quasi experimental study.","authors":"Atul Gupta, Pritam Halder, Rachana Srivastava, Savitesh Kushwaha, Madhu Gupta, Manmeet Kaur, Poonam Khanna","doi":"10.1186/s41043-025-00786-6","DOIUrl":"10.1186/s41043-025-00786-6","url":null,"abstract":"<p><strong>Introduction: </strong>Large meal portions contribute to the rise in Body Mass Index (BMI) leading to higher burden of Non-Communicable Diseases (NCDs), especially among the youths. College students frequently exhibit poor dietary habits; thus, it is important to pay attention to their eating habits in order to lower their risk for NCD. Therefore, we conducted this study with objective to measure the effect of health promotion intervention for small portion size consumption behaviour on body mass index (BMI) among college students in Chandigarh, India.</p><p><strong>Methods: </strong>We conducted this quasi-experimental research among college students aged 18-21 years from two colleges with co-education, having same streams considered as intervention and control from 2019 to 2020. Motivating group therapy, individual counselling, classroom training including power point presentations, lectures, and messaging via WhatsApp were implemented to the intervention group. No intervention was applied to the control group.</p><p><strong>Results: </strong>Overall, the mean BMI decreased in the both the intervention (n = 149) and control groups (n = 142) between the baseline and 6 months post intervention follow up period. The difference in difference (DID) of mean using paired t-test analysis showed that the estimated difference between the two groups was statistically significant for BMI (0.21; 95% CI 0.117-0.244; p-value < 0.001) and for waist hip ratio (0.02; 95% CI 0.001-0.005; p-value 007). There was reduction of 8.1% (from 28.9 to 20.8%) in obese, while 2.7% (from 44.3 to 47.0%) increase in participants with normal BMI in intervention. On the contrary there was almost no change in the proportion of obese and overweight participants in control group after 6 months.</p><p><strong>Conclusion: </strong>Considering the higher surge of obesity especially among the Indian youths, this study provided significant contribution in the field of public health in view of effective health promotion intervention to reduce BMI levels, by which get hold of the rising trend of this alarming problem. We recommend pragmatic community level large scale randomised control trials with frequent and controlled follow up to generate further evidence.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"260"},"PeriodicalIF":2.4,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between resting metabolic rate and hyperuricemia: is a higher metabolic rate better?","authors":"Guo Jinhao, Zheng Jiarui, Yin Xianglin, Qiu Hongbin, Wei Jinfeng","doi":"10.1186/s41043-025-01014-x","DOIUrl":"10.1186/s41043-025-01014-x","url":null,"abstract":"<p><p>Basal metabolic rate, resting metabolic rate, and resting energy expenditure are frequently utilised for the same research aims, but the underlying mechanisms separating them from human metabolic rate and metabolic disease remain poorly understood.Furthermore, specific recommendations for the prevention and management of hyperuricemia in populations with different resting metabolic rates have not been proposed, or how to reduce the public health burden of hyperuricemia based on resting metabolic rate and other factors have not been explored.[Methods] From 2011 to 2018, we selected 3268 adult participants from the National Health and Nutrition Examination Survey (NHANES). The modified Harris-Benedict equation was used to compute resting metabolic rate, and NHANES laboratory tests were used to acquire all biochemical parameters. A multivariate logistic regression analysis was performed to look at the relationship between hyperuricemia and resting metabolic rate. [Results] The multifactorial corrected model's second through fourth quartiles of RMR levels compared to the first quartile had relative advantage ratios of 1.258 (0.883 to 1.793), P > 0.05, 1.569 (1.024 to 2.404), P < 0.05, and 2.570 (1.555 to 4.247), P < 0.001 for men, respectively, following analysis.Subgroups of sexes Following analysis, the relative advantage ratios for the second and third tertiles of RMR levels for males were 1.157 (0.712 to 1.880), P > 0.05, and 1.991 (1.187 to 3.338), P < 0.05, respectively, when compared to the first tertile in the multifactorial corrected model.The female subgroup's adjusted postmenopausal RMR levels had relative dominating ratios of 1.157 (0.767 to 1.743), P > 0.05; 1.683 (0.955 to 2.967), P > 0.05; and 2.140 (0.965 to 4.747), P > 0.05 for the second through fourth quartiles. For the second through fourth quartiles of adjusted postmenopausal RMR levels in the female subgroup, the relative dominance ratios were 1.186 (1.005 to 3.082), P < 0.05; 2.302 (1.043 to 5.081), P < 0.05; and 1.192 (0.792 to 1.794), P > 0.05.[Conclusion] There was a positive correlation between resting metabolic rate and hyperuricemia. This pattern was also shown when gender subgroups were examined, with women over 45 being particularly susceptible to the association between hyperuricemia and resting metabolic rate.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"258"},"PeriodicalIF":2.4,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social media food marketing landscape of children living in Republic of Srpska, Bosnia and Herzegovina: Piloting the WHO CLICK framework, results and lessons learned.","authors":"Jelena Niškanović, Dragana Stojisavljević, Magdalena Muc, Mimi Tatlow-Golden, Dijana Manigoda","doi":"10.1186/s41043-025-01009-8","DOIUrl":"10.1186/s41043-025-01009-8","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Monitoring food marketing that reaches children is key to effective implementation of any regulation. The Best-ReMaP European Union Joint Action aimed to test the feasibility of using monitoring protocols (developed by the World Health Organization's Regional Office for Europe [WHO-Euro]) in the public health sector, to inform EU-wide monitoring plans. In Republic of Srpska, BiH, we piloted the WHO 'CLICK' Framework step, 'L - Landscape of campaigns', created to assess the nature of digital food and beverage marketing that children are potentially exposed to when using their preferred digital media.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This mixed methods pilot study analysed 235 Instagram and Facebook posts from 10 brands/products popular among children in Republic of Srpska, and 24 videos of two YouTube influencers, between January-April 2023. The WHO Nutrient Profile Model (1st edition, 2015) was used to assess ads' eligibility to be marketed to children. With WHO-Euro monitoring Protocols we assessed the promotional techniques (ad's creative power) used by brands and YouTube influencers. Finally, we assessed feasibility at every step of the process.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Research capacity and coding were among the main identified challenges in the pilot. Our learnings contributed to updates of the WHO Protocols and the EU- framework guidance. Regarding the food marketing landscape, the most frequently advertised food categories on social media and in YouTube Influencers' content were cakes, sweet biscuits and pastries (31% and 22.7% respectively) and chocolate and sugar confectionery (27.5% and 14.7% respectively). None of the social media ads were eligible to be marketed to children and only of 2 of the 24 YouTube influencers' marketing instances were eligible. Most ads featured elements potentially appealing to teens, 88% on Facebook and 72% on Instagram. The most frequently used persuasive appeals on social media were reference to holidays, travel, or adventure (23%), followed by taste (12.5%) and premium/contest (11.5%). YouTube influencers predominantly presented branded foods (62.5%). Only one influencer video featured a marketing disclosure. Food cue contexts varied between the two influencers, depending on their target groups. One mostly posted videos filmed at home, with child appeals and referred positively to the food featured; the other presented food as a secondary object and in neutral rather than positive contexts.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The WHO-Euro 'landscape' Protocol is a feasible tool for Member States to evaluate digital food marketing. Facilitators were: capacity/resources, access to a knowledge/experience exchange, and regular protocol updates. The analysis shows that in Republic of Srpska, BiH, powerful marketing of unhealthy foods appealing to children takes place on children's favoured social media platforms and via influencers with child-appealing content. Mandatory, g","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"257"},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a conceptual framework for relief goods distribution during disasters: a multi-method qualitative study.","authors":"Ramin Rezapour, Taher Doroudi, Saber Azami-Aghdash, Dariush Jafarzadeh, Naser Derakhshani","doi":"10.1186/s41043-025-01016-9","DOIUrl":"10.1186/s41043-025-01016-9","url":null,"abstract":"<p><strong>Background: </strong>Natural disasters and crises persistently affect human societies, often resulting in substantial loss of life and property. A major challenge during such events is the rapid and efficient distribution of relief goods to affected populations. This study aims to develop a Relief Goods Distribution Conceptual Framework (RGDCF) during disasters in Iran.</p><p><strong>Methods: </strong>This study was conducted in four phases. In the first phase, a comprehensive literature review was conducted to identify challenges in the distribution of relief goods and strategies for improvement. The second phase involved semi-structured interviews with national experts and stakeholders to examine the characteristics and requirements of an appropriate distribution framework for relief goods. In the third phase, drawing on the findings from the previous phases and expert panel discussions, an initial RGDCF was developed. Finally, in the fourth phase, the Delphi technique was employed to validate the proposed framework.</p><p><strong>Results: </strong>A review of 18 studies identified key challenges in the distribution of relief goods, including lack of coordination among responsible authorities, needs assessment problems, damage to infrastructure, financial challenges and management of public donations, lack of local community participation, weakness in disaster preparedness, and shortage of trained personnel. The RGDCF was developed, based on four core principles: pre-disaster preparedness, unified command and management, intersectoral coordination, and community engagement, with 15 operational requirements aimed at improving distribution efficiency and equity. The developed framework received an acceptable score in terms of its feasibility, alignment with higher-level documents, stakeholder acceptance, and flexibility.</p><p><strong>Conclusion: </strong>The RGDCF offers a comprehensive approach to addressing the challenges in relief goods distribution, ensuring more efficient and equitable humanitarian response. Its feasibility, alignment with existing policies, and stakeholder acceptance highlight its potential for practical implementation, as well as providing a structured basis for monitoring, evaluating, and improving relief operations in disaster management.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"255"},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the impact of a community health worker training program.","authors":"Kevin Crawford, Sarah Febres Cordero, Susan Brasher, Lalita Kaligotla, Quyen Phan, Laika Steiger, Roxana Chicas, Anne Spaulding, Beth Ann Swan","doi":"10.1186/s41043-025-01011-0","DOIUrl":"10.1186/s41043-025-01011-0","url":null,"abstract":"<p><strong>Background: </strong>The Atlanta Region Community Health Workforce Advancement (ARCHWAy) program is designed to train and empower Community Health Workers (CHWs) by centering marginalized voices and integrating theoretical knowledge with hands-on experience. Through a combination of online and in person didactic training, and experiential learning, the program prepares CHWs to address social determinants of health (SDOH) and advocate for health equity.</p><p><strong>Methods: </strong>This program evaluation examined the program's impact on participants' knowledge skills, and competencies. Feedback from course evaluations and encounter logs highlighted the program's effectiveness in equipping CHWs with practical tools to support individuals facing mental health crises, chronic disease management challenges, and barriers to healthcare access.</p><p><strong>Results: </strong>Participants rated the in-person and online didactic curriculum 4.5 or higher on a scale of 1-5. Experiential learning had a positive impact on their abilities to provide services such as individual and community assessment and education, and care coordination and to address the SDOH. Participants reported that they learned how to navigate systems, build trust, and empower individuals to advocate for their own health and well-being.</p><p><strong>Discussion: </strong>Findings suggested that ARCHWAy successfully fostered critical skills and strengthened the CHW workforce, reinforcing the importance of experiential learning and community-centered training. Participants expressed a strong sense of preparedness and commitment to their roles, emphasizing the need for sustained investment in CHW development, including long-term support and recognition. While challenges remain in securing sustainable funding and measuring long-term community health outcomes, the evaluation demonstrated the impact of one CHW training program.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"256"},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined effects of dietary inflammatory index and vigorous physical activity on abdominal adipose tissue: analysis of NHANES 2011-2018.","authors":"Shuoqi Li, Wenbo Fan, Yan Liu, Shiming Li, Wenbing Yu","doi":"10.1186/s41043-025-00991-3","DOIUrl":"10.1186/s41043-025-00991-3","url":null,"abstract":"<p><strong>Background: </strong>The accumulation of abdominal visceral (VAT) and subcutaneous adipose tissue (SAT) has been closely correlated with an array of metabolic disorders and chronic inflammation. This study elucidated the joint effects of a dietary inflammatory index (DII) and vigorous intensity physical activity (PA) on VAT and SAT.</p><p><strong>Methods: </strong>The study enrolled 3,444 adults sourced from the National Health and Nutrition Examination Survey (NHANES). The NHANES is designed with a sophisticated, multistage probability sampling methodology and is specifically tailored to comprehensively assess the health and nutritional conditions of the non-institutionalized population. Utilizing the initial 24 h dietary recall data from the NHANES database, our analysis incorporated 28 distinct food parameters for calculating the DII score. Multiple linear regression models are used to calculate the β value and 95% confidence interval of independent and dependent variables.</p><p><strong>Results: </strong>Compared with the pro-inflammatory diet group, VAT and SAT in the anti-inflammatory diet group were lower [-21.60 (-32.63, -10.58, P < 0.01) and - 85.67 (-108.80, -62.55, P < 0.01)]. The VAT and SAT in the sufficient vigorous intensity PA group were lower than those in the insufficient vigorous intensity PA group [-27.13 (-38.40, -15.86), P < 0.01; -57.05 (-80.82, -33.27), P < 0.01]. There was a linear positive association between DII with VAT (P < 0.01, P for nonlinearity = 0.13) and SAT (P < 0.01, P for nonlinearity = 0.06). Additionally, there were significant L-shaped relationships between vigorous intensity PA with VAT and SAT (all log-likelihood ratio P < 0.05).</p><p><strong>Conclusion: </strong>A lifestyle of anti-inflammatory diet incorporated with sufficient vigorous intensity PA was associated with lower VAT and SAT. Notably, the increase of vigorous intensity PA is associated with the decrease of VAT and SAT in the L-shaped relationships, suggesting that the vigorous intensity PA with at least 75 min per week may be related to greater benefits of VAT.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"254"},"PeriodicalIF":2.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between body folate status and muscle mass: a cross-sectional study of the National Health and Nutrition Examination Survey 2011-2018.","authors":"Zhi Chen, Jing Chen, Dingxiang Hu, Chengjian Wu, Zhengru Wu, Jiajun Lin","doi":"10.1186/s41043-025-01005-y","DOIUrl":"10.1186/s41043-025-01005-y","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is a progressive muscle disease associated with loss of muscle mass, strength and function. Previous studies have shown that folate and muscle function are related, but the effect of body folate status on muscle mass is unknown. This study aimed to investigate the relationship between different forms of folate and muscle mass.</p><p><strong>Methods: </strong>This cross-sectional study analyzed data from the 2011-2018 National Health and Nutrition Examination Survey (NHANES). Data on body folate (5-Methyl-tetrahydrofolate (5MTHF), serum total folate, and RBC folate), muscle mass (quantified by appendicular skeletal muscle mass index, ASMI), and covariates were extracted and analyzed. To examine the relationship between folate status and ASMI, weighted multivariable linear regression analyses and smooth curve fittings were performed, followed by subgroup analysis stratified by age, gender, and race. Threshold effect analysis was conducted when a nonlinearity relationship was detected.</p><p><strong>Results: </strong>A total of 13,850 participants were included in the final analysis. RBC folate was positively associated with ASMI in all three models. Serum total folate and 5MTHF were negatively associated with ASMI in unadjusted and partially adjusted model, but not in fully adjusted model. When stratified by age, gender, and race, we observed positive associations between RBC folate and ASMI in 20-40 years old participants, men, Mexican/Hispanic, Non-Hispanic Black, and Other Race. Smooth curve fitting demonstrated a nonlinear relationship between RBC folate and ASMI, with the inflection point identified at 512 ng/mL. Stratified by age, gender, and race, nonlinear relationships remained in 20-40 years old participants, Men, Non-Hispanic Black and Other Race, with inflection points identified at 468 ng/mL, 547 ng/mL, 400 ng/mL, and 494 ng/mL, respectively.</p><p><strong>Conclusion: </strong>These findings suggested folate deficiency might play a role in muscle loss, and maintenance of RBC folate above 512 ng/mL might be helpful to the prevention and treatment of sarcopenia.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"250"},"PeriodicalIF":2.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between hemoglobin glycation index and mortality in critically ill patients: a retrospective cohort study.","authors":"Liwei Pan, Fengfeng Lu, Bihuan Cheng, Wenwu Zhang, Benji Wang","doi":"10.1186/s41043-025-01008-9","DOIUrl":"10.1186/s41043-025-01008-9","url":null,"abstract":"<p><strong>Background: </strong>Glycemic variability is increasingly recognized as a critical factor influencing outcomes in intensive care, yet its prognostic role remains unclear. The Hemoglobin Glycation Index (HGI), which reflects individual glycemic variation, has not been thoroughly studied in critically ill populations.</p><p><strong>Aim: </strong>To evaluate the association between HGI and all-cause mortality in critically ill patients using data from a large intensive care unit (ICU) cohort.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the MIMIC-IV database. The primary outcomes were 30-, 90-, and 365-day all-cause mortality; in-hospital mortality was secondary. Kaplan-Meier analysis, Cox regression, and restricted cubic spline (RCS) modeling were used to assess mortality risk across HGI levels. Propensity score matching (PSM) and subgroup analyses were performed to ensure robustness.</p><p><strong>Results: </strong>Among 9,695 patients, those with low HGI (< - 0.40) had significantly higher mortality (P < 0.001). RCS analysis showed a nonlinear association between HGI and 30-day mortality. Higher HGI values were independently associated with reduced risk of death at all time points, with hazard ratios ranging from 0.43 to 0.76 (P < 0.001). These associations persisted after multivariable adjustment and PSM. Subgroup analyses showed consistent results across patient characteristics.</p><p><strong>Conclusions: </strong>Lower HGI values are associated with increased short- and long-term mortality in critically ill patients. HGI may serve as a valuable prognostic biomarker for risk stratification in ICU settings.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"249"},"PeriodicalIF":2.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}