Journal of Family Medicine and Primary Care最新文献

{"title":"Guillain-Barré syndrome with bilateral extensor plantar responses: A rare case report.","authors":"Midhun Mohan, Ramakant Yadav, Ajay Emani Ramamurthy","doi":"10.4103/jfmpc.jfmpc_2009_25","DOIUrl":"10.4103/jfmpc.jfmpc_2009_25","url":null,"abstract":"<p><p>Guillain-Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy, typically presenting with rapidly progressive symmetrical limb weakness and areflexia. However, upper motor neuron signs, such as extensor plantar responses, are occasionally reported, suggesting overlapping central nervous system features and presenting diagnostic challenges. We report a rare case of GBS with cranial nerve onset, bilateral facial diplegia, ascending limb weakness, and bilateral extensor plantar responses. A 34-year-old woman presented with an acute onset of bilateral facial weakness followed by progressive limb weakness and distal paresthesia after a brief febrile illness. Neurological examination revealed lower motor neuron bilateral facial palsy, proximal limb weakness, impaired joint position sensation, and bilateral extensor plantar response. Deep tendon reflexes were diminished in the lower limbs and brisk in the upper limbs. Magnetic resonance imaging of the brain and spine was normal. Cerebrospinal fluid analysis demonstrated albuminocytological dissociation. Nerve conduction studies showed features of demyelinating polyneuropathy. The patient initially worsened following corticosteroid therapy but showed significant improvement after treatment with intravenous immunoglobulin. At follow-up, she achieved near complete recovery with minimal residual facial weakness. This report highlights the diagnostic and therapeutic challenges of atypical GBS variants and emphasizes the importance of early recognition and appropriate management.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2153-2155"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lemierre syndrome making an encore in the post-antibiotic era: A case report.","authors":"Leidi Pedraza Gonzalez, Joanna I Depasupil, Ronique Gordon, Esra Fakioglu, Partha Chatterjee, Lily Q Lew","doi":"10.4103/jfmpc.jfmpc_2194_25","DOIUrl":"10.4103/jfmpc.jfmpc_2194_25","url":null,"abstract":"<p><p>Lemierre syndrome is a rare complication of an acute oropharyngeal infection. The disease is characterized by antecedent protracted pharyngitis, septic thrombophlebitis of the internal jugular vein, and secondary septic embolization to distant sites. We present a case of a previously healthy 17-year-old female with a sore throat and unilateral neck pain of 3-day duration. She tested positive for cytomegalovirus, Epstein-Barr virus, and <i>Mycoplasma pneumoniae</i>. Lemierre syndrome was diagnosed by contrast-enhanced computed tomography (CT) of the neck and chest. She experienced full recovery after four weeks of combined beta-lactam antibiotic and metronidazole and no anticoagulant therapy. Lemierre syndrome remains a diagnostic challenge due to its rarity. In the post-antibiotic era, atypical causative pathogens are commonly seen. Contrast-enhanced CT of the neck serves as the gold standard for the diagnosis of Lemierre syndrome. This case highlights the importance of having a high index of suspicion for an early accurate diagnosis, appropriate treatment, and optimal outcome.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2143-2146"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical perspectives and stewardship imperatives in the study of acute exacerbations of chronic obstructive pulmonary disease.","authors":"Shraddha Bapat, Divya Madamanchi","doi":"10.4103/jfmpc.jfmpc_400_26","DOIUrl":"10.4103/jfmpc.jfmpc_400_26","url":null,"abstract":"","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2169-2170"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protecting the health of healers: A UK primary care perspective on lifestyle medicine and professional culture.","authors":"Mustafa Al-Gburi","doi":"10.4103/jfmpc.jfmpc_422_26","DOIUrl":"10.4103/jfmpc.jfmpc_422_26","url":null,"abstract":"","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2167-2168"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of lipid profile, D-dimer, and insulin resistance among preeclamptic, gestational hypertensive, and healthy normal pregnant women: A comparative cross-sectional study at rural tertiary care centre.","authors":"Nivedita Singh, Ajai Kumar, Soniya Vishwakarma, Pradeep Sharma, Kalbe Jawad","doi":"10.4103/jfmpc.jfmpc_2260_25","DOIUrl":"10.4103/jfmpc.jfmpc_2260_25","url":null,"abstract":"<p><strong>Background: </strong>Among the various complications, Hypertensive disorder of pregnancy (HDP) has increased maternal and perinatal morbidity and mortality on a global scale. Metabolic changes and abnormalities in Blood coagulation and fibrinolysis are manifestations in patients with HDP, and such changes are related to various metabolic parameters.</p><p><strong>Aim: </strong>To investigate the correlation between lipid profile, D-dimer levels, and insulin resistance in pre-eclampsia, gestational hypertensive, and healthy pregnant women.</p><p><strong>Materials and methods: </strong>A comparative cross-sectional study conducted in collaboration with the Department of Obstetrics and Gynecology and with Department of Biochemistry at Uttar Pradesh University of Medical Sciences, from January 2022 to July 2023. 120 antenatal women were enrolled in each group (Healthy women as Control, Gestational Hypertension, and Preeclampsia). Pearson's correlation coefficient assessed the relationship between fasting serum insulin and other parameters.</p><p><strong>Results: </strong>Group 1 showed a higher mean serum insulin than Group 2 and controls (<i>P</i> < 0.001). Regarding fasting blood sugar (FBS), Group 2 had a mean FBS significantly higher than Group 1 and controls (<i>P</i> < 0.001). For D-dimer levels, Group 2 had a significantly higher mean than Group 1 and controls (<i>P</i> < 0.001). According to Pearson Correlation, insulin levels correlated positively and significantly with D-dimer and serum triglycerides, LDL cholesterol, VLDL, Cholesterol/HDL ratio, LDL/HDL ratio, and Triglycerides/HDL ratio.</p><p><strong>Conclusion: </strong>These metabolic biomarkers may play a role in the pathophysiology of these pregnancy-related conditions. Hence, they are implicated in the prognosis of women with HDP.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2094-2099"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lupus enteritis: A rare masquerade of intestinal tuberculosis.","authors":"Sumeet Sawale, Ananda Datta, Archana Malik, Lee Chang M Sangma, Pratyaksha Kumari, Rajesh Kumar, Pradosh Kumar Sarangi, Harsihchandra Rameshkumar Bohra","doi":"10.4103/jfmpc.jfmpc_1605_24","DOIUrl":"10.4103/jfmpc.jfmpc_1605_24","url":null,"abstract":"<p><p>Lupus enteritis is a rare clinical entity with a global incidence of 0.2%-14.2%. Signs and symptoms of lupus enteritis are nonspecific, and incidence is very low; it is often misdiagnosed as tuberculosis (TB) in endemic countries like India. Also, enteritis as initial presentation is quite uncommon in systemic lupus erythematosus. We are reporting a case of a 15-year-old woman of lupus enteritis who was misdiagnosed as intestinal TB.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2140-2142"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of maternal knowledge towards Rhesus incompatibility and their attitude about its preventive measures in Jeddah, Saudi Arabia.","authors":"Abdulrahman Adel Hawari, Jumanah Y Nassar, Alaa M Kadah Salim, Eatedal M AlShareef, Nada M AlFarrah","doi":"10.4103/jfmpc.jfmpc_1947_24","DOIUrl":"10.4103/jfmpc.jfmpc_1947_24","url":null,"abstract":"<p><strong>Background: </strong>Rh incompatibility arises when a Rh-negative woman carries a Rh-positive fetus, which can lead to Rh alloimmunization and complications. A tertiary care center in Jeddah, Saudi Arabia, reported a tenfold higher prevalence of Rh alloimmunization compared to developed countries. This study aimed to assess maternal knowledge, attitudes, and perspectives on Rh incompatibility, including its complications and preventive measures, in Jeddah, Saudi Arabia.</p><p><strong>Methods: </strong>This is a descriptive, cross-sectional study that was applied among community mothers, primiparous, and multiparous females living in Jeddah, Saudi Arabia. Data collection took two months, from June 1, 2024, to July 31, 2024. The data were analyzed using SPSS version 29 and the quantitative variables are presented as numbers and percentages.</p><p><strong>Results: </strong>The mean age of participants was 38 ± 10 years, with equal representation of Saudi and non-Saudi women (50% each). Marital status distribution showed 93% married, 5% divorced, and 2% widowed. Key factors linked to higher knowledge scores included younger age, higher education levels, and antenatal care attendance. Younger mothers had better scores, as did those with higher educational attainment and antenatal care experience.</p><p><strong>Conclusion: </strong>Our findings suggest a significant gap in understanding the Rh factor, despite the majority of the participants being aware of it. Moreover, higher levels of education and younger age are associated with better knowledge scores, perhaps providing an opportunity for focused educational programs in the future.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"1919-1925"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of integrated interdisciplinary postgraduate workshops with competency-based assessment: A mixed method approach.","authors":"Aradhana Sanga, Anjali Borle, Khushbo Rani, Zenith H Kerketta, Deepali Tirkey, D K Sinha, Sunil K Mahto, K Sandhya","doi":"10.4103/jfmpc.jfmpc_204_26","DOIUrl":"10.4103/jfmpc.jfmpc_204_26","url":null,"abstract":"<p><strong>Background: </strong>An interdisciplinary curriculum refers to curriculum organisation that cuts across subject matter lines to focus upon comprehensive life problems or broad-based areas of study that brings together the various segments of the curriculum into meaningful association. The current study is intended to improve the knowledge and application of subject across the departments to build a strong foundation for future clinicians and enhance interdepartmental coordination.</p><p><strong>Objective: </strong>The study was done to compare the Integrated post-session (OSCE) Objective structured clinical examination/(OSPE) Objective structured Practical examination scores with the traditional scores of two groups followed by a Focus Group Discussion.</p><p><strong>Method: </strong>Forty two first year postgraduate residents from Surgery, pathology and anatomy departments in the year 2025 included a pre-test on knowledge and skill of the participants followed by an integrated session on the topic decided based on Postgraduate competency, randomization of the inclusion group into an intervention group having demonstrate, observe, assist and perform session followed by post-test and Focus group Discussion whose participants were recruited by purposive sampling.</p><p><strong>Conclusion: </strong>Beneficial impact of the intervention on knowledge and skill of the participants post intervention was noted with statistically significant mean score difference of 9.79 ± 1.87 and 12.38 ± 3.03. Focus Group Discussion analysis yielded 13 deductive codes 7 sub-codes and 3 themes being i) increase competency, ii) content integration, and iii) positive personal and social impact. Integrated interdisciplinary post graduate workshop with competency-based assessment will not only enhance Participant satisfaction with skill enhancement, but also promote Interdisciplinary collaboration.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2034-2039"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the stroke-COVID link solid? A critical analysis of Aghamiri <i>et al</i>.'s research methodology and findings.","authors":"Basil Joy","doi":"10.4103/jfmpc.jfmpc_1053_24","DOIUrl":"10.4103/jfmpc.jfmpc_1053_24","url":null,"abstract":"","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2177-2178"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of stratification of households based on health needs in Mugalur village, Anekal taluk-An exploratory study.","authors":"Teny Attokaran, Gokul K Madhav, Farah N Fathima, Vishak S Rao, R Chandan, H Stephen, Twinkle Agrawal","doi":"10.4103/jfmpc.jfmpc_348_26","DOIUrl":"10.4103/jfmpc.jfmpc_348_26","url":null,"abstract":"<p><strong>Introduction: </strong>Stratifying households helps identify those at higher health risk and supports focused interventions. This study assessed the feasibility of creating a household stratification tool in rural Mugalur village, Anekal Taluk, to enhance community health services by classifying households according to their healthcare needs.</p><p><strong>Methodology: </strong>A stratification tool was developed by a brainstorming session with public health professionals, identifying key health conditions across age groups, along with relevant social and environmental risk factors. These were categorised into high, medium, and low priority, represented by red, yellow, and green colour codes, respectively. High-priority households were scheduled for monthly visits, medium-priority households once every two months, and low-priority households once every six months. The tool was administered to all households in the village.</p><p><strong>Results: </strong>Among 332 households, 18.1% were classified as red, 45.8% as yellow, and 36.1% as green. Chronic conditions were more common among older adults, while the presence of young children or pregnancy often increased household priority. Larger family size and lower socioeconomic status were significantly associated with higher priority status. Notably, several high-priority households were not receiving the recommended frequency of health worker visits, indicating gaps in service delivery.</p><p><strong>Conclusion: </strong>The stratification tool was feasible to implement in this rural setting. By identifying households with greater health needs, it can support community health workers in optimising visit schedules and improving the efficiency and equity of home-based care.</p>","PeriodicalId":15856,"journal":{"name":"Journal of Family Medicine and Primary Care","volume":"15 5","pages":"2069-2075"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}