Journal of Evolutionary Biochemistry and Physiology最新文献

{"title":"A Comparative Distribution of Parvalbumin-Immunopositive Neural Elements in the Spinal Cord of Newborn and Adult Cats","authors":"A. A. Veshchitskii, A. V. Belyaev, N. S. Merkulyeva","doi":"10.1134/s0022093024030049","DOIUrl":"https://doi.org/10.1134/s0022093024030049","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>We performed a comparative immunohistochemical analysis of\u0000parvalbumin, a calcium-binding protein, expression in the lumbosacral\u0000spinal cord of newborn and adult cats. In contrast to adult animals,\u0000parvalbumin immunostaining in newborn kittens was mainly detected\u0000in the sensory fibers located in the dorsal horns and medial part\u0000of the intermediate gray matter. The location of these fibers partially\u0000recapitulates the position of the Clarke’s nuclei, but is not limited\u0000by their classical boundaries, spanning the entire length of the\u0000lumbar spinal cord and transitioning into the putative Stilling’s\u0000nuclei in the sacral region. Thus, in newborn kittens, in contrast\u0000to adult animals, parvalbumin-immunopositive proprioceptive fibers\u0000appear to make up a single network. We hypothesize that with age,\u0000this continuous system of fibers undergoes restructuring due to\u0000maturation and spreading of the neuronal and neuropil components\u0000of the lumbar enlargement, responsible primarily for the locomotor\u0000control. As a result, two local groups of interneurons, the Clarke’s\u0000and Stilling’s nuclei, form. The only parvalbumin-immunopositive\u0000spinal neurons in newborn kittens are premotor interneurons located\u0000along the lamina IX curvature. These neurons are characterized by\u0000a weak or no immunolabeling of the neuronal marker protein NeuN,\u0000which is indicative of a special neurochemical status of these neurons.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"31 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141522283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Dihydroquercetin on the Intensity of Oxydative Stress in Rat Liver Mitochondria at Hypothermia","authors":"R. A. Khalilov, A. M. Dzhafarova, Z. G. Rabadanova, M. B. Dzhafarov","doi":"10.1134/s0022093024030153","DOIUrl":"https://doi.org/10.1134/s0022093024030153","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>A decrease in body temperature in homeothermic animals can\u0000cause a state of the body called hypothermic. It is accompanied\u0000by the development of a number of pathological processes, many of which\u0000are associated with mitochondrial dysfunction and the development\u0000of oxidative stress. In connection with the widespread introduction\u0000of hypothermia into medical practice, the question of the possibility\u0000of a regulatory influence on the proxidant-antioxidant status of\u0000mitochondria at low body temperatures remains relevant. In recent\u0000years, plant polyphenols, in particular dihydroquercetin (DHQ),\u0000have gained wide popularity as therapeutic agents with antioxidant\u0000and membrane protective effects. In this work, we investigated the\u0000effects of DHQ on the intensity of oxidative stress in rat liver mitochondria\u0000under moderate hypothermia. It was found that a course (5 days)\u0000oral administration of DHQ at a dose of 100 mg/kg significantly\u0000reduces the levels of lipid peroxidation (LPO) and oxidative modification\u0000of proteins (OMP) products in the liver mitochondria of control\u0000rats, increasing the content of non-enzymatic components of the\u0000thiol-disulfide antioxidant system’s. DHQ effectively protects liver\u0000mitochondria from the development of oxidative stress during hypothermia,\u0000as evidenced by a significant decrease (and in some cases, complete\u0000normalization) in the levels of diene conjugates, MDA, Schiff bases\u0000and carbonyl groups in a group of animals subjected to hypothermia\u0000with prior administration of this polyphenol. At the same time,\u0000DHQ significantly increases the levels of glutathione and vitamin\u0000E, and also normalizes the content of thiol groups in mitochondrial\u0000proteins. In vitro, DHQ exhibits a dose-dependent antioxidant effect,\u0000suppressing OMB in mitochondria incubated in Fenton’s medium (IC₅₀ =\u00000.160 mg/mL).</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"33 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141522294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Cardarine on Gene Expression of Proteins Involved in Epileptogenesis in Rat Hippocampus in the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy","authors":"A. R. Kharisova, A. I. Roginskaya, O. E. Zubareva","doi":"10.1134/s0022093024030177","DOIUrl":"https://doi.org/10.1134/s0022093024030177","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>During the last years, the role of astro- and microglial cells\u0000and associated neuroinflammation in the pathogenesis of epilepsy\u0000has been extensively discussed. These cells can be in different\u0000functional state. The extreme A1 and M1 phenotypes producing predominantly\u0000pro-inflammatory (promoting epileptogenesis) proteins and the A2\u0000and M2 phenotypes producing anti-inflammatory (preventing epileptogenesis)\u0000proteins. It has been suggested that the use of drugs that can stimulate\u0000polarisation from M1 and A1 to M2 and A2 phenotypes may be a successful\u0000strategy for the treatment of epilepsy. Such drugs include agonists\u0000of peroxisome proliferator-activated receptor nuclear receptors\u0000(PPARs). The aim of this study was to investigate changes in the\u0000expression of micro- and astroglial proteins involved in the regulation\u0000of epileptogenesis in the dorsal hippocampus of rats in the lithium-pilocarpine\u0000model of temporal lobe epilepsy (TLE) and to investigate the effect\u0000of the PPAR agonist beta/delta cardarine on these processes. Cardarine\u0000was administered at the initial stages of epileptogenesis (within\u00007 days after induction of the TLE model), and two months later (chronic\u0000phase of the model) we analysed the expression of genes of interest\u0000in the dorsal hippocampus by real-time RT-PCR. The performed study revealed\u0000changes in gene expression of astro- and microglial proteins during\u0000epileptogenesis, mainly associated with the enhancement of neuroinflammatory\u0000processes and weakening of neuroprotective properties of these cells.\u0000In TLE rats the expression of genes of markers of astro- (<i>Gfap</i>) and microglia activation (<i>Aif1</i>), pro- (<i>Il1b</i>, <i>Nlrp3</i>) and anti-inflammatory (<i>Il1rn</i>) proteins, markers of the A1 phenotype\u0000of astrocytes (<i>Lcn2</i>, <i>Gbp2</i>) and growth factors (<i>Bdnf</i>, <i>Fgf2</i>)\u0000was increased. Gene expression of the protective M2 phenotype <i>Arg1</i> gene was decreased in TLE rats.\u0000The most striking effect of cardarine administration was manifested\u0000in the enhanced expression of the marker A2 gene of the <i>S100a10</i> astrocyte phenotype.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"14 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141522360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 5-HT3 Receptor-Dependent Facilitatory Influence of the Infralimbic Cortex on the Caudal Ventrolateral Medulla Visceral Pain-Related Neurons and Its Colitis-Associated Changes in Rats","authors":"O. A. Lyubashina, I. B. Sivachenko","doi":"10.1134/s0022093024030268","DOIUrl":"https://doi.org/10.1134/s0022093024030268","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The medial prefrontal cortex has been shown to participate\u0000in pain processing and to undergo structural and functional changes\u0000in chronic visceral pain syndromes. Its infralimbic region (IL)\u0000is directly involved in central autonomic regulation and provides\u0000extensive projections to pain-related brain centers, being most\u0000capable of modulating visceral nociception. However, the precise\u0000neuronal and molecular mechanisms underlying IL-exerted descending\u0000control of visceral pain and their probable alterations in pathology\u0000remain unknown. Considering the high levels of serotonin 5-HT3 receptors\u0000in the IL and their important role in visceral pain regulation,\u0000in this study performed in anesthetized adult male Wistar rats,\u0000we aimed to determine whether 5-HT3 receptor-dependent mechanisms\u0000are involved in the IL influence on visceral pain-responsive neurons\u0000of the caudal ventrolateral medulla (CVLM) and whether intestinal\u0000inflammation affects the process. Our results showed that electrical\u0000stimulation of the IL caused a facilitation of both excitatory and\u0000inhibitory CVLM neuron responses to noxious colorectal distension\u0000(CRD). Both effects were 5-HT3-dependent, being decreased following intracerebroventricular\u0000injection of a 5-HT3-antagonist, granisetron (20 µg in 10 µL saline).\u0000In trinitrobenzenesulfonic acid-induced colitis, the IL stimulating\u0000influence on CRD-excited CVLM neurons intensified, while the cortex-driven\u0000facilitation of CRD-inhibited cells reduced; both appeared resistant\u0000to the 5-HT3 receptor blockade. These data provide an insight to\u0000the specific mechanisms underlying cortical modulation of acute\u0000and gut pathology-associated visceral nociception, promoting the\u0000development of differentiated strategies for their treatment.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"25 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141522368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to: Influence of Interval Hypoxic Training in Different Regimes on the Blood Parameters of Rats","authors":"K. A. Baranova, M. Y. Zenko, E. A. Rybnikova","doi":"10.1134/s0022093024020352","DOIUrl":"https://doi.org/10.1134/s0022093024020352","url":null,"abstract":"","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"3 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140803349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Event Related Potentials’ Characteristics in the Different Models of Verbal Creative Thinking","authors":"N. V. Shemyakina, Zh. V. Nagornova","doi":"10.1134/s0022093024020029","DOIUrl":"https://doi.org/10.1134/s0022093024020029","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The comparative study of three different models of creative\u0000thinking in unified event-related (ERP) paradigm is presented. The\u0000subjects (18–35 years old) performed the following tasks: PROVERBS\u0000(a divergent creative task to overcome stereotypes of long-term\u0000memory), REMOTE ASSOCIATIONS (a convergent creative task activating\u0000remote semantic fields), ALTERNATIVE USES TASK (a divergent creative\u0000task with the initiation of the associative search process). In\u0000the creative tasks, subjects required to create an original ending\u0000to a proverb (Pr), find a word that could be matched with three\u0000presented words from different semantic fields (RAT), invent original\u0000ways of using common objects (AUT). In the control tasks subjects\u0000were required to recall a well-known ending to a proverb (PrM),\u0000and to list/name objects from a given category (CAT). The ERP amplitudes\u0000were analyzed when comparing the tasks with each other. Greater\u0000negativity was observed for the a component with around 300 ms latency\u0000(~N300) in frontal regions (280–346 ms after stimuli onset) in the\u0000Pr task, which probably reflects inhibition of the patterns of long-term\u0000memory. In the Pr and RAT tasks, semantic retrieval and integration\u0000of new information versus retrieval of known information from memory\u0000(PrM) was characterized by lower amplitude values of late components\u0000at the 698–786 ms interval. The greater amplitude of late ERP components\u0000in parietal regions (524–624 ms) during divergent thinking (AUT)\u0000may correspond to the greater emergence of images in this task compared\u0000to more abstract RAT and Pr tasks. Thus, even in the early stages\u0000of information processing in verbal creative tasks performance,\u0000the specificity of different models of creative thinking appears\u0000in the same temporal paradigm and similar visual stimuli presentation.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"28 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140803354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of the Humoral Immune Response When Using Protein Immobilized on the Surface of Nano- and Microparticles Based on Poly(Lactic Acid)","authors":"R. G. Sakhabeev, D. S. Polyakov, E. S. Sinitsyna, V. A. Korzhikov-Vlakh, I. O. Bagaeva, E. G. Korzhikova-Vlakh, T. P. Ses, V. S. Tereshina, M. M. Shavlovsky","doi":"10.1134/s0022093024020030","DOIUrl":"https://doi.org/10.1134/s0022093024020030","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The study is aimed at evaluating the influence of composition\u0000and size of micro- and nanoparticles (MPs and NPs) on the immunogenicity\u0000of protein antigen associated with them. For comparative analysis,\u0000MPs and NPs based on poly(lactic acid) (PLA) and block copolymer\u0000of poly(ethylene glycol) with poly(lactic acid) (PEG-<i>b</i>-PLA) were obtained. Recombinant\u0000human beta2-microglobulin fusion protein with superfolder green\u0000fluorescent protein (β2M-sfGFP) was used for covalent modification\u0000of all types of polymer particles. Immobilization of the model protein\u0000β2M-sfGFP was carried out on the surface of the particles through\u0000the reaction of activated esters with the amino groups of the protein. Immunization\u0000of mice using complex antigen (β2M-sfGFP protein immobilized on\u0000the surface of MPs and NPs of different compositions) was carried\u0000out in four steps. Immunogenicity was assessed by the level of specific\u0000antibodies to sfGFP using enzyme-linked immunoassay. The results\u0000showed a significant increase in antibody levels in the control\u0000groups, which were immunized with a mixture of model protein and\u0000particles of different nature and sizes, compared to the experimental\u0000groups, which were immunized with conjugates of the corresponding\u0000particles with model protein. In the experimental groups, the highest\u0000number of specific antibodies was detected in the case of immunization\u0000of mice with the conjugate of protein and PLA or PEG-<i>b</i>-PLA-based NPs. The introduction\u0000of PEG block into the PLA composition did not significantly affect\u0000the immunogenicity of the protein, while the particle size was of significant\u0000importance. Protein bound to PLA- or PEG-<i>b</i>-PLA-based\u0000NPs showed higher immunogenicity compared protein bound to MPs of\u0000the same compositions, which can be used for practical purposes\u0000to develop vaccines (NP-protein) or “trapping systems” (MP-protein)\u0000that bind infiltrating viruses.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"19 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140886280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction between Endocrine and Exocrine Pancreas","authors":"A. Mostafa, E. A. Gantsova, O. V. Serova, T. Mohammad, I. E. Deyev","doi":"10.1134/s0022093024020273","DOIUrl":"https://doi.org/10.1134/s0022093024020273","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The pancreas plays a key role in the endocrine system of animals,\u0000as well as in the digestion and absorption of nutrients. The exocrine\u0000and endocrine portions of the pancreas are structurally separated from\u0000each other, however, multiple studies suggest the anatomical and\u0000functional unity between them. While previously, the interactions\u0000of these two portions received less attention, nowadays the pancreas\u0000is considered as a single organ consisting of functionally interlinked\u0000components, which coordinates endocrine and exocrine responses.\u0000The review addresses the latest data indicating the functional relationship\u0000and reciprocal influence of the endocrine and exocrine pancreatic\u0000portions. In addition, we consider the impact of SARS-CoV-2 infection\u0000on pancreatic function.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"38 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140886404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conscious and Unconscious Processes in the Arithmetic Priming Task Depend on the Arithmetic Skill","authors":"V. M. Knyazeva, N. V. Polyakova, D. G. Fedorov, D. D. Sitnikova, A. A. Aleksandrov","doi":"10.1134/s0022093024020261","DOIUrl":"https://doi.org/10.1134/s0022093024020261","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The study examined the role of conscious and unconscious processes\u0000depending on the level of arithmetic skill. The participants were\u0000divided into two groups according to their arithmetic skill based on\u0000the calculation fluency test results. Masked and unmasked single-digit\u0000addition problems (primes) followed by correct and incorrect results\u0000were presented on the screen. In a conscious perception task (unmasked\u0000priming), when large and small problem results were presented, an\u0000arithmetic N400 and LPC effects were observed in both groups. In\u0000the case of unconscious perception (masked priming), when small\u0000problem results were presented, the LPC effect was observed in the\u0000group with low arithmetic skill. The fact that the LPC arithmetic\u0000effect was discovered during the unconscious presentation may indicate the\u0000automatic nature of the encoding and retrieving information processes,\u0000reflecting neurophysiological characteristics associated with the\u0000level of arithmetic skill.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"148 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140886484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mercury and Low Molecular-Weight Antioxidants Levels in Ungulates of the Republic of Karelia","authors":"S. N. Kalinina, V. A. Ilyukha, V. T. Komov, I. A. Zaitseva, I. V. Baishnikova, D. V. Panchenko, E. P. Antonova","doi":"10.1134/s0022093024020078","DOIUrl":"https://doi.org/10.1134/s0022093024020078","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The high toxicity of mercury (Hg) poses a danger to the environment\u0000and humans, but studies of the concentration of this metal in organisms\u0000of terrestrial ecosystems are few. Ecotoxicologists also pay little attention\u0000to studying the role of antioxidant vitamins in protecting cells\u0000from toxic metals. The Republic of Karelia is one of the northwestern\u0000regions of Russia, the biogeochemical features of which can contribute\u0000to an increase in the mobility and bioavailability of Hg in food\u0000chains. The purpose of the work was to determine the concentration\u0000of Hg in the liver, kidneys, muscle and hair of ungulate mammals\u0000of the Republic of Karelia (wild boar <i>Sus\u0000scrofa</i> L. and moose <i>Alces alces</i> L.)\u0000and to analyze the relationship between the level of this toxic\u0000metal and the content of low molecular-weight antioxidants—reduced\u0000glutathione, retinol and α-tocopherol. Species and tissue-specific\u0000of the studied parameters in wild boars and moose are noted. The\u0000observations discovered by other researchers that omnivorous species\u0000accumulate more Hg in their tissues compared to herbivores, and\u0000also that this toxic metal is predominantly accumulated in the kidneys,\u0000while muscles contain a minimal amount, have been confirmed. Hg\u0000concentrations in most samples of liver and kidney of wild boars\u0000and in all samples of the same organs of moose were within the limits\u0000recorded for domestic pigs and deer, respectively. The levels of\u0000Hg we recorded in the tissues and hair of wild boars and moose were\u0000generally comparable to or lower than the levels of this metal noted\u0000in animals from other regions of Russia and other countries of the world.\u0000In wild boars and moose of Karelia, no statistically significant\u0000relationships were found between the Hg level and the content of\u0000the studied antioxidants in the internal organs. Moose were characterized by\u0000a higher content of α-tocopherol in the body than wild boars, which\u0000is a feature of this type of herbivorous ungulate mammal. The results\u0000of the study indicate a relatively low level of mercury pollution\u0000in terrestrial ecosystems in Karelia.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"8 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140886375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}