Journal of Exercise Rehabilitation最新文献

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Analysis of professional football players' sprint performance efficiency in matches. 职业足球运动员比赛冲刺表现效率分析。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652496.248
Jeong-Hyun Shim, Chang-Hwa Joo
{"title":"Analysis of professional football players' sprint performance efficiency in matches.","authors":"Jeong-Hyun Shim, Chang-Hwa Joo","doi":"10.12965/jer.2652496.248","DOIUrl":"10.12965/jer.2652496.248","url":null,"abstract":"<p><p>The purpose of this study is to analyze the efficiency of the high-intensity exercise performances of professional players during matches. Thirty professional players competed in a total of 38 matches throughout the season. 1,558 sprint efforts were recorded and subsequently analyzed. The sprint efficiency assessment tool ensured good interrater reliability (intraclass correlation coefficient, 0.892; 95% confidence interval, 0.883-0.901) and the validity of the analysis was confirmed by four experts with more than 20 years of experience in football. The total distance and low-intensity running were higher during the first half than during the second half of the season (<i>P</i><0.01). The positions covering the greatest distances were full back and midfielder. High-intensity running (<i>P</i><0.05) and sprinting (<i>P</i><0.01) were higher during home matches than during away matches. The sprint efficiency was higher during the second half than during the first half of the season (<i>P</i><0.05), but the maximum velocity was higher during the first half of the season (<i>P</i><0.01). Sprint efficiency was higher for the attack than for the defense and defensive transition situations (<i>P</i><0.05). Higher duration, distance, and maximum velocity were observed for the excellent efficiency group than for the appropriate group (<i>P</i><0.05). In conclusion, the findings of this study suggest that the development of effective training programs to enhance high-intensity exercise performance, such as sprinting, requires consideration that goes beyond simply physical speed enhancement to encompass situational judgment, timing, path selection, and speed regulation in an integrated way.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"158-166"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a neuromuscular exercise program on lower limb alignment and balance ability in individuals with genu varum and knee pain. 神经肌肉锻炼计划对膝内翻和膝关节疼痛患者下肢对齐和平衡能力的影响。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652470.235
Hyung-Hoon Moon, Sung-Ki Lee, Jeong-Ha Lee, Sang-Seo Park, Sang-Min Lee, Won-Moon Kim, Yong-Gon Seo
{"title":"Effects of a neuromuscular exercise program on lower limb alignment and balance ability in individuals with genu varum and knee pain.","authors":"Hyung-Hoon Moon, Sung-Ki Lee, Jeong-Ha Lee, Sang-Seo Park, Sang-Min Lee, Won-Moon Kim, Yong-Gon Seo","doi":"10.12965/jer.2652470.235","DOIUrl":"10.12965/jer.2652470.235","url":null,"abstract":"<p><p>This study examined the effects of a neuromuscular exercise program on knee joint alignment, pain, and static and dynamic balance in patients with genu varum. Forty female patients aged 40-60 years with radiographically confirmed genu varum and a Short-Form McGill Pain Questionnaire (SF-MPQ) score ≥18.0 were randomly assigned to either an exercise group (EG, n=20) or a control group (CG, n=20). The EG participated in a supervised neuromuscular exercise program 3 times per week for 12 weeks (60 min/session), while the CG maintained usual daily activities. Radiographic assessments included knee-to-knee length (KTKL), hip inclination angle (HIA), and medial proximal tibial angle (MPTA). Pain was evaluated using the SF-MPQ. Static and dynamic plantar pressure were measured using a pressure analysis system. Data were analyzed using two-way mixed analysis of variance to examine interactions, with Bonferroni correction applied for <i>post hoc</i> analyses (<i>P</i><0.05). Significant interactions were observed for KTKL, bilateral HIA, bilateral MPTA, and pain scores (all <i>P</i><0.001). The EG demonstrated reductions in KTKL (-1.09 cm) and pain (-8.15), as well as increases in HIA (right: +1.56°, left: +1.39°) and MPTA (right: +1.11°, left: +0.89°), whereas the CG showed minimal changes. For balance outcomes, significant interactions were identified in selected static and dynamic balance measures (<i>P</i><0.05), with <i>post hoc</i> analyses indicating improvements primarily in the EG. A 12-week neuromuscular exercise program may be beneficial for improving alignment-related measures, reducing pain, and enhancing selected balance outcomes in individuals with genu varum.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"137-146"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of different rest intervals following postactivation performance enhancement on multiple components of performance-related fitness in elite athletes. 运动后不同休息时间对优秀运动员运动相关体能的影响。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652416.208
Chan-Gyun Oh, Dong-Eun Kim, Tae-Beom Seo
{"title":"Effects of different rest intervals following postactivation performance enhancement on multiple components of performance-related fitness in elite athletes.","authors":"Chan-Gyun Oh, Dong-Eun Kim, Tae-Beom Seo","doi":"10.12965/jer.2652416.208","DOIUrl":"10.12965/jer.2652416.208","url":null,"abstract":"<p><p>This study aimed to investigate the effects of different rest intervals following postactivation performance enhancement (PAPE) on upper- and lower-body skill-related physical fitness in elite athletes. Seven male elite athletes participated in a crossover design and completed four experimental conditions: the control (CON), the 3-min rest (R3), the 8-min rest (R8), and the 12-min rest (R12) groups following PAPE. In the PAPE conditions, participants performed additional warm-up sets at 50% and 70% of one-repetition maximum, followed by one set of five-repetition maximum bench press and squat, whereas the CON did not include PAPE. Results showed that upper-body agility significantly improved in the R3 and R12 groups compared to the CON group (<i>P</i><0.05), whereas upper-body power and balance showed no significant changes. Lower-body power and balance were significantly enhanced, with the most consistent improvements observed in the R3 group (<i>P</i><0.05), while lower-body agility did not significantly differ among conditions. In whole-body performance, coordination significantly improved in the R3 group compared to the CON group (<i>P</i><0.05), whereas reaction time and sprint performance were not significantly affected. Overall, the effects of PAPE varied according to performance task and body region, with significant improvements mainly observed in upper-body agility, lower-body power and balance, and whole-body coordination, particularly following the R3 interval. Shorter recovery intervals may provide benefits for selected performance outcomes in elite athletes.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"121-127"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing hand hygiene compliance among elderly caregivers: based on the theory of planned behavior. 老年护理人员手卫生依从性的影响因素:基于计划行为理论。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652468.234
Tae Young Kim, Nam Hyun Cha
{"title":"Factors influencing hand hygiene compliance among elderly caregivers: based on the theory of planned behavior.","authors":"Tae Young Kim, Nam Hyun Cha","doi":"10.12965/jer.2652468.234","DOIUrl":"10.12965/jer.2652468.234","url":null,"abstract":"<p><p>This study aimed to identify factors influencing hand hygiene compliance among long-term care workers in long-term care facilities based on the theory of planned behavior (TPB). A cross-sectional survey was conducted with 133 long-term care workers from four long-term care facilities in Daegu Metropolitan City and Gyeongsangbuk-do, South Korea. Self-reported questionnaires assessed hand hygiene-related belief factors (behavioral, normative, and control beliefs), core TPB factors (attitude toward behavior, subjective norms, and perceived behavioral control), intention, and hand hygiene compliance. Descriptive statistics, <i>t</i>-tests, analysis of variance, Pearson correlation, and multiple regression analysis were performed. The mean scores for hand hygiene attitude, subjective norms, and behavioral intention exceeded the scale midpoint, whereas the scores for control beliefs and perceived behavioral control were relatively lower. Hand hygiene compliance was significantly correlated with behavioral beliefs (<i>r</i>=0.23, <i>P</i>=0.008), control beliefs (<i>r</i>=0.26, <i>P</i>=0.002), attitude toward behavior (<i>r</i>=0.18, <i>P</i>=0.038), perceived behavioral control (<i>r</i>=0.41, <i>P</i><0.001), and intention (<i>r</i>=0.31, <i>P</i><0.001). Multiple regression analysis identified perceived behavioral control (<i>β</i>=0.33, <i>P</i>=0.002) and intention (<i>β</i>=0.23, <i>P</i>=0.006) as significant predictors of compliance, explaining 19.1% of the variance (Adjusted <i>R</i> <sup>2</sup>=0.191). Perceived behavioral control and intention were identified as significant predictors of hand hygiene compliance. Interventions should not only enhance knowledge but also address structural and organizational factors to strengthen caregivers' perceived control and translate intention into practice.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"128-136"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Habitual elbow joint use time is associated with pain adaptation but not strength performance in young adults: a cross-sectional multithreshold classification study. 年轻人习惯性肘关节使用时间与疼痛适应有关,但与力量表现无关:一项横断面多阈值分类研究。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652436.218
Dong Hyun Yoo, Yong-Seok Jee
{"title":"Habitual elbow joint use time is associated with pain adaptation but not strength performance in young adults: a cross-sectional multithreshold classification study.","authors":"Dong Hyun Yoo, Yong-Seok Jee","doi":"10.12965/jer.2652436.218","DOIUrl":"10.12965/jer.2652436.218","url":null,"abstract":"<p><p>This study investigated the differences between weekly elbow joint use time, pain level, and isokinetic moment in young adults using multiple exposure classification strategies. A total of 67 participants were categorized using three grouping approaches: median-based (<6 hr vs. ≥6 hr/wk), quartile-based (<6, 6-8, 8-10, and >10 hr/wk), and threshold-based (<10 hr vs. ≥10 hr/wk). Elbow joint pain was assessed using a visual analog scale and isokinetic moment was assessed using an isokinetic dynamometer at angular velocities of 60°/sec, 120°/sec, and 180°/sec for both flexion and extension. Across all classification approaches, nondominant elbow pain was consistently lower in higher-use groups (<i>P</i><0.05), whereas dominant-side pain did not differ significantly. Most isokinetic moments were also comparable between groups; however, dominant flexor peak torque at 120°/sec was slightly lower in the ≥10 hr/wk group (<i>P</i>=0.049). These findings suggest that weekly elbow joint use time is more strongly associated with pain-related neuromuscular adaptation than with measurable strength performance in young adults. Multithreshold classification approaches may provide a more comprehensive framework for evaluating exposure-related upper-extremity functional characteristics.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"110-120"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opening the 2026 Spring Conference of the Korean Society of Exercise Rehabilitation. 韩国运动康复学会2026年春季会议开幕。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652643.323
Chang-Ju Kim
{"title":"Opening the 2026 Spring Conference of the Korean Society of Exercise Rehabilitation.","authors":"Chang-Ju Kim","doi":"10.12965/jer.2652643.323","DOIUrl":"https://doi.org/10.12965/jer.2652643.323","url":null,"abstract":"","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"109"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of sarcopenia on functional independence and depression in older adults: a cross-sectional study. 肌肉减少症对老年人功能独立和抑郁的影响:一项横断面研究。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-08-26 eCollection Date: 2026-08-01 DOI: 10.12965/jer.2652526.263
Tae-Hyun Yoon, Yong-Seok Jee
{"title":"Influence of sarcopenia on functional independence and depression in older adults: a cross-sectional study.","authors":"Tae-Hyun Yoon, Yong-Seok Jee","doi":"10.12965/jer.2652526.263","DOIUrl":"10.12965/jer.2652526.263","url":null,"abstract":"<p><p>Differences in physical function, encompassing activities of daily living (ADL) and instrumental activities of daily living (IADL), and depression were evaluated across degrees of sarcopenic severity in older adults. A total of 236 participants (78.72±6.92 years), comprising 101 men and 135 women, were classified into four groups: no sarcopenia (23.7%), possible sarcopenia (26.3%), sarcopenia (28.0%), and severe sarcopenia (22.0%). Sarcopenic measures included calf girth, grip strength, 5-time chair stand test, and appendicular skeletal muscle mass. Functional status was assessed using Barthel Index for ADL and Lawton & Brody index for IADL, while depression was measured using the Geriatric Depression Scale-15. All sarcopenic indices differed significantly between groups, with large effect sizes (<i>η</i> <i><sup>2</sup></i> =0.340-0.532). ADL and IADL declined with increasing sarcopenic severity, and after age and sex adjustments, physical function (all <i>P</i><0.001) and depressive symptoms remained significantly different across groups. Analysis of covariance showed that age was independently associated with ADL, IADL, and depression. The association between sarcopenia severity and ADL differed by sex (<i>P</i>=0.011), whereas the relationships of sarcopenia severity with IADL and depression were not influenced by sex. These findings suggest that greater sarcopenia severity is associated with poorer physical function and a higher burden of depressive symptoms. However, while the relationship between sarcopenia severity and ADL appears to be influenced by sex, the associations of IADL and depression with sarcopenia severity seem to be largely driven by age rather than sex.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 4","pages":"147-157"},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution of manuscript peer review: expanding roles in exercise rehabilitation research. 论文同行评议的演变:在运动康复研究中的扩展作用。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-06-23 eCollection Date: 2026-06-01 DOI: 10.12965/jer.2652392.196
Yong-Seok Jee
{"title":"Evolution of manuscript peer review: expanding roles in exercise rehabilitation research.","authors":"Yong-Seok Jee","doi":"10.12965/jer.2652392.196","DOIUrl":"10.12965/jer.2652392.196","url":null,"abstract":"","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 3","pages":"71-72"},"PeriodicalIF":1.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13328781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of ballet versus weight-bearing exercise on body composition, physical fitness, and isokinetic muscle function in obese women. 芭蕾与负重运动对肥胖女性身体成分、体能和等速肌肉功能的影响。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-06-23 eCollection Date: 2026-06-01 DOI: 10.12965/jer.2652304.152
Yu-Mi Kim, Yeong-Jik Kim, Chan-Gyun Oh, Tae-Beom Seo, Young-Pyo Kim
{"title":"Effects of ballet versus weight-bearing exercise on body composition, physical fitness, and isokinetic muscle function in obese women.","authors":"Yu-Mi Kim, Yeong-Jik Kim, Chan-Gyun Oh, Tae-Beom Seo, Young-Pyo Kim","doi":"10.12965/jer.2652304.152","DOIUrl":"10.12965/jer.2652304.152","url":null,"abstract":"<p><p>This study compared the effects of ballet exercise and a weight-bearing exercise program on body composition, basic physical fitness, and isokinetic knee muscle function in obese women. Twenty-three participants were randomly assigned to the control group (CG, n=7), ballet exercise group (BEG, n=10), and weight-bearing exercise group (WBEG, n=6). Both exercise groups performed 60-min sessions, 3 times a week, with progressively increased intensity. Body weight and percent body fat decreased significantly only in the BEG (<i>P</i><0.05 and <i>P</i><0.01), while no significant changes were observed in skeletal muscle mass across all groups. In the basic physical fitness, the BEG and WBEG showed significant improvements in back strength, flexibility, and left-side dynamic balance, whereas sit-up performance and right-side balance improved significantly only in the BEG. For isokinetic knee muscle function, the results were differentiated between muscle strength (60°/sec) and muscular endurance (240°/sec). At 60°/sec, both exercise groups showed significant improvements primarily in left knee extensor strength, including peak torque and relative peak torque. At 240°/sec, both groups demonstrated significant increases in extensor total work for both limbs, indicating enhanced muscular endurance. Additionally, the BEG showed improvements in right knee flexor total work and average power. These findings suggest that ballet exercise is associated with improvements in body composition, basic physical fitness, and lower-limb muscle function in obese women. In particular, ballet exercise may provide comparable benefits to weight-bearing exercise in enhancing isokinetic muscle function, while offering additional advantages in core endurance and unilateral balance.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 3","pages":"78-85"},"PeriodicalIF":1.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13328782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined effects of treadmill exercise and naringenin treatment on neuronal survival and corticospinal tract fibers sprouting after spinal cord injury. 跑步机运动和柚皮素联合治疗对脊髓损伤后神经元存活和皮质脊髓束纤维发芽的影响。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-06-23 eCollection Date: 2026-06-01 DOI: 10.12965/jer.2652256.128
Yeong-Jik Kim, Tae-Beom Seo
{"title":"Combined effects of treadmill exercise and naringenin treatment on neuronal survival and corticospinal tract fibers sprouting after spinal cord injury.","authors":"Yeong-Jik Kim, Tae-Beom Seo","doi":"10.12965/jer.2652256.128","DOIUrl":"10.12965/jer.2652256.128","url":null,"abstract":"<p><p>The purpose of this study was to investigate the combined effects of treadmill exercise and naringenin treatment on neuronal survival and corticospinal tract (CST) fibers sprouting following spinal cord injury (SCI). Forty male rats were randomly assigned to four groups (n=10 in each group): the normal group (Norm), the SCI+sedentary group (SCI+S), the SCI+naringenin group (SCI+Na), and the SCI+naringenin combined with exercise group (SCI+Na+Ex, n=10). All rats in the SCI were allowed to recover for 2 weeks after injury, and the exercise group subsequently underwent 4 weeks of low-intensity treadmill exercise. Histological and molecular analyses were performed to evaluate astrocyte activation in the dorsal region, neuronal survival in the ventral horn, and axonal elongation in the caudal CST fibers following SCI. As a result, in the dorsal region of the injury site, both treatment groups showed significantly increased glial fibrillary acidic protein expression compared to the SCI+S group, indicating enhanced astrocyte activation. In particular, the SCI+Na+Ex group demonstrated prominent astrocytic infiltration into the cavity. In the ventral horn of the injured spinal cord, the number of motor neurons was significantly preserved in the SCI+Na+Ex group compared to the SCI+S group. In the caudal CST, the SCI+Na+Ex group exhibited significantly increased neurofilament-200 expression, suggesting enhanced axonal regeneration. Furthermore, regeneration-associated proteins including growth-associated protein-43 and activating transcription factor-3 were significantly increased following the combined intervention. Combined treatment of treadmill exercise and naringenin might be one of the rehabilitation strategies to promote neural recovery after SCI.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 3","pages":"86-94"},"PeriodicalIF":1.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13328789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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