Journal of Diabetes and Metabolic Disorders最新文献_第4页

Adherence to treatment among patients with type 2 diabetes: short communication. 2型糖尿病患者的治疗依从性：短沟通

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-05-03 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01627-3

Donya Sadeghi, Asieh Darvish

{"title":"Adherence to treatment among patients with type 2 diabetes: short communication.","authors":"Donya Sadeghi, Asieh Darvish","doi":"10.1007/s40200-025-01627-3","DOIUrl":"10.1007/s40200-025-01627-3","url":null,"abstract":"Background and purpose: Undesirable adherence to treatment is one of most important challenges in the control and treatment of type 2 diabetes. Therefore, the present study was conducted with the aim of determining the level of adherence to treatment and factors affecting it among patients with type 2 diabetes in Tehran.Methods: This cross-sectional descriptive study was conducted in 2023 on 117 patients with diabetes referred to Imam Khomeini Hospital in Tehran. The data collection tool was the Hill-Bone Medication Adherence Scale (HB-MAS), which was completed by the participants. Version 16 SPSS and descriptive analysis at the statistical level of 0.05 were used to analyze the data.Results: The mean age of the participants in this research was 45.06 ± 8.48 years. The results showed that 41.03% of the participants had the desirable treatment adherence and 58.97% had the undesirable treatment adherence. A significant relationship was observed between the compliance of patients with the variables of gender, level of education and job status (P < 0.05); But the variables of age, duration of illness and type of treatment had no significant relationship with treatment adherence.Conclusion: The findings showed that the level of adherence to treatment in patients with type 2 diabetes in Tehran is not undesirable. It is better for the treatment team to take more effective measures to improve the awareness of patients in adherence to treatment. Planners and policy makers should also take more effective measures to empower patients to access health services.Supplementary information: The online version contains supplementary material available at 10.1007/s40200-025-01627-3.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"112"},"PeriodicalIF":1.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unravelling the association of glycosylated haemoglobin A1c, blood pressure, and LDL-cholesterol (ABC) with all-cause mortality in Type 2 diabetes patients: insights from a middle-income country. 揭示糖化血红蛋白A1c、血压和低密度脂蛋白胆固醇（ABC）与2型糖尿病患者全因死亡率的关系：来自中等收入国家的见解

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-30 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01620-w

Mohamad Zulfikrie Abas, Noran Naqiah Hairi, Wan Yuen Choo, Kim Sui Wan, Kezhi Li

{"title":"Unravelling the association of glycosylated haemoglobin A1c, blood pressure, and LDL-cholesterol (ABC) with all-cause mortality in Type 2 diabetes patients: insights from a middle-income country.","authors":"Mohamad Zulfikrie Abas, Noran Naqiah Hairi, Wan Yuen Choo, Kim Sui Wan, Kezhi Li","doi":"10.1007/s40200-025-01620-w","DOIUrl":"10.1007/s40200-025-01620-w","url":null,"abstract":"Introduction: This study evaluated the risk of all-cause mortality among Type 2 Diabetes (T2D) patients in Malaysia, correlating it with glycosylated haemoglobin A1c (HbA1c), blood pressure (BP), and LDL-Cholesterol (LDL-C) - the ABC parameters. This would fill the evidence gap from middle-income countries like Malaysia.Methods: This retrospective cohort study analysed data from National Diabetes Registry and death records for 90,933 T2D patients in southern Malaysia (2011-2021). ABC parameters were categorized into quantiles, and adjusted hazard ratios (aHR) were estimated using Cox regression with the lowest-risk quantile as reference.Results: All-cause mortality showed a 'J-shaped' association across ABC parameters. For HbA1c, aHRs (95% CI) were 1.11 (1.03-1.19) and 1.51 (1.40-1.63) in the first and last deciles (reference: fourth decile). For BP and LDL-C (reference: third quantile), aHRs were 1.11 (1.05-1.17) and 1.19 (1.13-1.24) for systolic BP, and 1.08 (1.03-1.14) and 1.16 (1.11-1.22) for LDL-C at the lowest and highest quintiles. For diastolic BP, aHRs were 1.09 (1.02-1.16) and 1.11 (1.04-1.19) at the lowest and highest quartiles.Conclusion: Maintaining optimal ABC parameters is crucial to reduce mortality in T2D patients. These findings fill critical gap in the literature, particularly for the Malaysian population.Supplementary information: The online version contains supplementary material available at 10.1007/s40200-025-01620-w.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"111"},"PeriodicalIF":1.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep neural network base competing risk in predicting heart failure patient's survival. 基于深度神经网络的竞争风险预测心衰患者生存。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-29 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01595-8

Solmaz Norouzi, Ebrahim Hajizadeh, Mohammad Asghari Jafarabadi, Nasim Naderi, Saeideh Mazloomzadeh

{"title":"Deep neural network base competing risk in predicting heart failure patient's survival.","authors":"Solmaz Norouzi, Ebrahim Hajizadeh, Mohammad Asghari Jafarabadi, Nasim Naderi, Saeideh Mazloomzadeh","doi":"10.1007/s40200-025-01595-8","DOIUrl":"10.1007/s40200-025-01595-8","url":null,"abstract":"Objectives: Heart failure (HF) is a complicated disease with several competing risks of interest, such as HF death and other causes. This study compares a Deep Neural Network Competing Risks (DNNCR) and Random Survival Forest (RSF) model to evaluate the predictive performance of time-to-event outcomes in HF patients with competing risks.Methods: This study represents the retrospective analysis of 435 HF patients admitted to RCMRC, Tehran, Iran, between March and August 2018. After a five-year follow-up in 2023, predictions were analyzed based on Cause of death. This study employed RSF and DNN methods to account for competing risks in survival analysis. Then, model fitness was applied using C-index and IBS.Results: The C-index of the results shows that DNNCR is superior to RSF in predicting survival outcomes for HF and other causes of death. Precisely, the C-index was 0.65 (0.04) for HF and 0.63 (0.02) for other causes of death in the DNNCR model, while in RSF, the C-index was 0.65 (0.04) for HF and 0.61 (0.03) for Other Causes. Additionally, calibration results showed via the IBS the finest performance of the DNNCR model at 0.16 for HF, followed by other causes with an IBS of 0.18.Conclusions: The study shows that the DNNCR model outperforms RSF in predicting survival outcomes for HF patients, particularly in the presence of competing risks. The improved accuracy enables physicians to identify high-risk individuals and tailor treatment plans accordingly. Future research could utilize more diverse datasets to enhance DNNCR performance and integrate these models into clinical tools.Graphical abstract: ","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"109"},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the obesity trend of overweight and obese people with pictograms among Iranian adults. 调查伊朗成年人中有象形图的超重和肥胖人群的肥胖趋势。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-24 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01618-4

Shima Ghannadi, Kazem Khalagi, Leyla Ostad Mohammdi, Reyhaneh Khazaei, Arash Balagabri, Hanieh-Sadat Ejtahed, Mohammad Hosein Pourgharib Shahi, Shirin Hasani-Ranjbar

{"title":"Investigating the obesity trend of overweight and obese people with pictograms among Iranian adults.","authors":"Shima Ghannadi, Kazem Khalagi, Leyla Ostad Mohammdi, Reyhaneh Khazaei, Arash Balagabri, Hanieh-Sadat Ejtahed, Mohammad Hosein Pourgharib Shahi, Shirin Hasani-Ranjbar","doi":"10.1007/s40200-025-01618-4","DOIUrl":"10.1007/s40200-025-01618-4","url":null,"abstract":"Purpose: Obesity is a major public health concern, particularly in resource-constrained areas where measuring it accurately is challenging due to insufficient equipment and trained personnel. In Iran, there is a notable lack of comprehensive longitudinal studies using modern tools to track adult obesity trends. This study employed body shape pictograms (BIP) to classify abdominal obesity and aimed to reveal trends in perceived obesity among Iranian adults.Methods: This cross-sectional study involved individuals from the multidisciplinary obesity registry at Shariati Hospital, from 2013 to February 2021. It included patients aged 30 to 65 with morbid obesity (BMI ≥ 35) who were potential bariatric surgery candidates. Medical history, anthropometric data, laboratory data, and the obesity pictogram were collected through face-to-face private interviews.Results: We recruited 346 participants (287 females and 59 males). The study found an upward trend in obesity, indicated by pictogram scores across all categories (p <.001). Mean pictogram scores significantly varied by obesity levels based on BMI (p <.001) and were positively associated with waist and hip circumference (p <.001). No significant associations were found with diabetes or metabolic syndrome status.Conclusion: This study underscores the significant trend of perceived obesity among Iranian adults, as assessed through pictograms. Accurate data on obesity trends among overweight and obese individuals over time can play a crucial role in shaping the country's health policies to combat obesity.Clinical trial number: Not applicable.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"108"},"PeriodicalIF":1.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highlighted gene expression alteration in human pancreatic isolated islets in patients with type 2 diabetes. 2型糖尿病患者胰岛基因表达改变

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-23 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01611-x

Vahid Mansouri, Babak Arjmand, Mohammad Rostami Nejad, Zahra Razzaghi, Mostafa Rezaei-Tavirani, Farideh Razi, Fatemeh Bandarian, Reza M Robati, Mitra Rezaei, Fatemeh Daneshimehr

{"title":"Highlighted gene expression alteration in human pancreatic isolated islets in patients with type 2 diabetes.","authors":"Vahid Mansouri, Babak Arjmand, Mohammad Rostami Nejad, Zahra Razzaghi, Mostafa Rezaei-Tavirani, Farideh Razi, Fatemeh Bandarian, Reza M Robati, Mitra Rezaei, Fatemeh Daneshimehr","doi":"10.1007/s40200-025-01611-x","DOIUrl":"10.1007/s40200-025-01611-x","url":null,"abstract":"Objectives: Type 2 diabetes is a complex disease characterized by progressive β-cell failure. The primary mechanism underlying this failure is the progressive loss of pancreatic β-cell function. The aim of this study is to identify the key gene expression changes in human pancreatic isolated islets of patients with type 2 diabetes.Methods: We extracted gene expression data in human pancreatic isolated islets of patients with type 2 diabetes and healthy controls from Gene Expression Omnibus (GEO) and analyzed it using GEO2R program. We then assessed the significant differentially expressed genes (DEGs) using protein-protein interaction (PPI) network analysis. The critical genes were enriched via gene ontology and discussed.Results: Among the 93 significant DEGs, five critical genes including ITGB2, APOE, BIRC5, GABRA2, and IL1B were emerged as key players in type 2 diabetes. Notably, \"Alzheimer disease, type 4\" was identified as a major class of biological terms altered in type 2 diabetes.Conclusions: Our findings suggest that the introduced critical genes are potential targets for controlling type 2 diabetes. Furthermore, the crucial role of APOE as a link between type 2 diabetes and Alzheimer's disease or other cognitive disorders was confirmed.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"107"},"PeriodicalIF":1.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MiR-568-5p, the key regulator of suppressor of cytokine signaling 4 (SOCS4) in the coronary artery disease. MiR-568-5p是冠状动脉疾病中细胞因子信号传导4 （SOCS4）抑制因子的关键调节因子。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-22 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01619-3

Tayebeh Sadeghi, Majid Zaki-Dizaji, Meisam Rostaminasab Dolatabad, Zahra Taheri

{"title":"MiR-568-5p, the key regulator of suppressor of cytokine signaling 4 (SOCS4) in the coronary artery disease.","authors":"Tayebeh Sadeghi, Majid Zaki-Dizaji, Meisam Rostaminasab Dolatabad, Zahra Taheri","doi":"10.1007/s40200-025-01619-3","DOIUrl":"10.1007/s40200-025-01619-3","url":null,"abstract":"Objectives: Pro-inflammatory molecules are key risk factors for coronary artery diseases (CAD). Therefore, the regulation of inflammatory responses plays a crucial role in CAD. Suppressor of cytokine signaling 4 (SOCS4) is a negative regulator of cytokine signaling may significantly contribute to the pathogenesis of CAD. Bioinformatics studies indicate that hsa-miR-568-5p can target SOCS4. This study aimed to evaluate the expression of hsa-miR-568-5p in patients with CAD and investigate its correlation with SOCS4 levels.Methods: The study included 20 Iranian participants without artery stenosis and 40 with artery stenosis. The relative expression levels of hsa-miR-568-5p and SOCS4 were assessed using Real-Time PCR.Results: The findings revealed no significant difference in the expression levels of hsa-miR-568-5p and SOCS4 between the two groups. Also, correlations were not observed between hsa-miR-568-5p, SOCS4, and age in both the control and CAD patient groups.Conclusions: While hsa-miR-568-5p regulates SOCS4 expression, and SOCS4 upregulation is implicated in coronary artery disease (CAD) protection, this study found no conclusive evidence supporting this relationship. Further research is warranted.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"106"},"PeriodicalIF":1.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-vitro investigation of antidiabetic and antioxidants properties of major prebiotics and plant based dietary fibers. 主要益生元和植物性膳食纤维抗糖尿病和抗氧化性能的体外研究。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-15 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01610-y

Faezeh Shirkhan, Saeed Mirdamadi, Mahta Mirzaei, Behrouz Akbari-Adergani, Nikoo Nasoohi

{"title":"In-vitro investigation of antidiabetic and antioxidants properties of major prebiotics and plant based dietary fibers.","authors":"Faezeh Shirkhan, Saeed Mirdamadi, Mahta Mirzaei, Behrouz Akbari-Adergani, Nikoo Nasoohi","doi":"10.1007/s40200-025-01610-y","DOIUrl":"10.1007/s40200-025-01610-y","url":null,"abstract":"Objectives: Consuming prebiotics and plant-based dietary fibers are important as an emerging approach to diabetes and oxidative stress control. In this study, the functional properties of major prebiotics and dietary fibers were evaluated.Methods: The hypoglycemic properties were analyzed by inhibiting α-amylase and α-glucosidase, glucose adsorption capacity, and glucose diffusion. Antioxidant capacity, total phenolic (TP), and flavonoid (TF) content were also measured.Results: The results showed that among prebiotics, isomaltulose and pectin had antidiabetic activity by α-amylase (IC50 = 11.36 mg/mL) and α-glucosidase (IC50 = 2.38 mg/mL) inhibition. Isomaltulose and pectin exhibited the ability to adsorb glucose capacity. Inulin HP showed the ability to inhibit glucose diffusion. The results also showed that all prebiotics impart antioxidant activity and TP, and TF content in a dose-dependent manner (p < 0.05). Pectin showed a higher ability to scavenge 1,1-diphenyl-2 picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzthiazoline-6-sul-fonate (ABTS) radicals with higher phenolic compound (p < 0.05). Therefore, it seems that pectin was able to reduce the rate of glucose adsorption, regulate glucose adsorption by enzyme activity inhibition, and increase antioxidant capacity.Conclusion: The results revealed that the prebiotics were efficient in their antidiabetic potential and could act as bio-functional materials. Using prebiotics in functional foods and nutraceutical medicines is strongly recommended.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"105"},"PeriodicalIF":1.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11999920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A scientometric analysis and visualization of research on fatty liver diseases in Iran from 2003 to 2023. 2003年至2023年伊朗脂肪肝研究的科学计量学分析和可视化

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-11 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01606-8

Ehsaneh Taheri, Hamideh Ehtesham, Reza Safdari, Ahmad Hormati

{"title":"A scientometric analysis and visualization of research on fatty liver diseases in Iran from 2003 to 2023.","authors":"Ehsaneh Taheri, Hamideh Ehtesham, Reza Safdari, Ahmad Hormati","doi":"10.1007/s40200-025-01606-8","DOIUrl":"10.1007/s40200-025-01606-8","url":null,"abstract":"Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide and is now a major global health threat. Due to the mechanistic links between these conditions, along with the rising prevalence of fatty liver disease, diabetes, and obesity, MAFLD (metabolic-associatedfatty liver diseases) was introduced as a new terminology and then updated to MASLD (Metabolic Dysfunction-associated Steatotic Liver Disease. These changes reflect a growing recognition of the importance of fatty liver and its associated health risks.Methods: This scientometric study analyzed publications on \"fatty liver diseases\" (FLD) indexed in Scopus from 2003 to 2023 in Iran. Online Analysis Platforms and VOSviewer were used to assess publication trends and identify research hotspots.Results: We retrieved 1,857 English articles on fatty liver diseases published between 2003 and 2023. The Journal of Hepatitis Monthly was notable for Iranian publications on fatty liver disease. Most publications were original articles and Dr. Sahebkar AH was the most prolific author. Iranian researchers primarily collaborated with scholars from the United States. The leading institution in terms of productivity was Tehran University of Medical Sciences.Conclusion: This study reveals an increasing trend in both the number of Iranian publications and the citations of articles in the field of FLD. We believe this study can serve as a roadmap for future research and policy development on fatty liver diseases, which are a significant public health concern in Iran. Additionally, new strategies are needed to foster multi-disciplinary research and enhance international cooperation.Supplementary information: The online version contains supplementary material available at 10.1007/s40200-025-01606-8.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"103"},"PeriodicalIF":1.8,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noncommunicable disease syndemic among the general population in Iran: a cross-sectional study. 伊朗普通人群中的非传染性疾病综合征：一项横断面研究。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-10 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01615-7

Zahra Torabi, Farshad Farzadfar, Negar Rezaei, Merrill Singer, Shahin Roshani, Maryam Tajvar, Elham Shakibazadeh

{"title":"Noncommunicable disease syndemic among the general population in Iran: a cross-sectional study.","authors":"Zahra Torabi, Farshad Farzadfar, Negar Rezaei, Merrill Singer, Shahin Roshani, Maryam Tajvar, Elham Shakibazadeh","doi":"10.1007/s40200-025-01615-7","DOIUrl":"10.1007/s40200-025-01615-7","url":null,"abstract":"Objectives: This study aims to investigate the status of the NCD syndemic among individuals over 25 in all provinces of Iran.Methods: This study was based on a national survey. Using a systematic cluster random sampling framework, 26,707 participants were selected from all 31 Iranian provinces. The data were analyzed for descriptive statistics by gender and age, followed by principal component analysis and logistic regression, using R software for the statistical analysis.Results: There was an interaction between diabetes mellitus and cardiovascular diseases, in their association with healthy life lost due to disability in the Iranian adult population. Additionally, there was a clustering of diabetes mellitus and cardiovascular diseases, partly due to the shared specific causes such as obesity, hypertension, shared baseline features, and poverty.Conclusions: The syndemic analysis showed that social inequalities in diabetes and cardiovascular disease arise not only from exposure levels but also from varying vulnerabilities and disease outcomes. Iran's health policy should prioritize reducing these health inequalities.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"102"},"PeriodicalIF":1.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11985718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients. 糖尿病和非糖尿病患者伤口护理中防腐剂的进展综述。

IF 1.8

Journal of Diabetes and Metabolic Disorders Pub Date : 2025-04-10 eCollection Date: 2025-06-01 DOI: 10.1007/s40200-025-01607-7

Mohammadreza Heidari, Ozra Tabatabaei-Malazy, Zahra Jahani, Mohammad Reza Amini, Marzieh Vahid Dastjerdi

{"title":"A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients.","authors":"Mohammadreza Heidari, Ozra Tabatabaei-Malazy, Zahra Jahani, Mohammad Reza Amini, Marzieh Vahid Dastjerdi","doi":"10.1007/s40200-025-01607-7","DOIUrl":"10.1007/s40200-025-01607-7","url":null,"abstract":"Wounds affect many people and require a considerable annual cost to manage. Wound infections significantly delay the healing process, particularly in individuals with diabetes mellitus, due to impaired immunity and microvascular complications. The use of antiseptics is considered a way to reduce this problem. The study aims to assess the different antiseptic categories frequently employed in wound management, focusing on identifying and understanding their unique features. A comprehensive review of PubMed, Scopus, and EMBASE databases identified key antiseptics, including isopropyl alcohol, chlorhexidine, polyhexanide, octenidine, povidone-iodine, hypochlorous acid, silver-based products, hydrogen peroxide, triclosan, and benzalkonium chloride. These antiseptics exhibit varying efficacies and cytotoxicity profiles, necessitating tailored usage to optimize healing while preventing antimicrobial resistance. The primary indication for antiseptics is the prevention of Surgical Site Infections (SSIs), as recommended by guidelines. For diabetic foot ulcers, the strongest evidence supports the use of hypochlorous acid. There are no universal recommendations for antiseptic use; their application depends on specific circumstances. This review highlights the need for evidence-based, condition-specific antiseptic strategies to address unique patient needs effectively.Supplementary information: The online version contains supplementary material available at 10.1007/s40200-025-01607-7.","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"101"},"PeriodicalIF":1.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11985748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0