{"title":"1990-2019年伊朗非传染性疾病负担及其四个主要亚组的性别差异:来自2019年全球疾病负担研究的系统分析","authors":"Mahdie Fatollahzade, Mohammad-Mahdi Bastan, Moez Shaabanian, Ali Golestani, Ozra Tabatabaei-Malazy, MohammadReza Mohajeri-Tehrani, MohammadReza Amini, Sepehr Khosravi, Hamid Pajavand, Bagher Larijani","doi":"10.1007/s40200-024-01489-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The significant health differences between sexes in Iran in terms of burden of non-communicable diseases (NCDs) point to the urgency of developing policies. We aim to explore sex disparities in NCDs.</p><p><strong>Methods: </strong>We used Global Burden of Disease 2019 study to compare estimates of incidence, prevalence, disability-adjusted life years (DALYs), years lived with disabilities (YLDs), years of life lost (YLLs), and deaths among sexes for NCDs, and their main subgroups; neoplasms, cardiovascular diseases (CVDs), chronic respiratory diseases (CRDs), diabetes mellitus (DM) during 1990-2019.</p><p><strong>Results: </strong>In 2019, there were 62,476,274 (59517167.5, 65759931) incident NCDs in men and 78758640.6 (75222093.7, 82272935.8) in women. There were 7734064.3 (6744951.2, 8846192) DALYs in men and 7760484.2 (6496609, 9218299.9) in women. Fatal estimates (deaths and YLLs) of NCDs were higher for men, while non-fatal estimates (prevalence, YLDs) were higher for women. Men were superior in all burden indices of NCDs subgroups, except for all indices of DM and YLDs in CVDs. Compared to 1990-2010, the period 2010-2019 confirmed a marked stagnation in decline rates of burden indices, as well as an increase in incidence and prevalence which was more pronounced among men. Despite shrinking sex gaps in NCDs subgroups since 1990, sex gap in DM is widening in 2019.</p><p><strong>Conclusions: </strong>There is a notable sex disparity in NCDs prevalence in Iran, which has become increasingly evident in DM burden. It will be imperative to continue monitoring sexual differences in NCDs burden to determine if disease rates between sexes continue to diverge in the future.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40200-024-01489-1.</p>","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"23 2","pages":"2207-2224"},"PeriodicalIF":1.8000,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599546/pdf/","citationCount":"0","resultStr":"{\"title\":\"Sex disparity in the burden of NCDs and its four main subgroups in Iran 1990-2019: a systematic analysis from the global burden of disease study 2019.\",\"authors\":\"Mahdie Fatollahzade, Mohammad-Mahdi Bastan, Moez Shaabanian, Ali Golestani, Ozra Tabatabaei-Malazy, MohammadReza Mohajeri-Tehrani, MohammadReza Amini, Sepehr Khosravi, Hamid Pajavand, Bagher Larijani\",\"doi\":\"10.1007/s40200-024-01489-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The significant health differences between sexes in Iran in terms of burden of non-communicable diseases (NCDs) point to the urgency of developing policies. We aim to explore sex disparities in NCDs.</p><p><strong>Methods: </strong>We used Global Burden of Disease 2019 study to compare estimates of incidence, prevalence, disability-adjusted life years (DALYs), years lived with disabilities (YLDs), years of life lost (YLLs), and deaths among sexes for NCDs, and their main subgroups; neoplasms, cardiovascular diseases (CVDs), chronic respiratory diseases (CRDs), diabetes mellitus (DM) during 1990-2019.</p><p><strong>Results: </strong>In 2019, there were 62,476,274 (59517167.5, 65759931) incident NCDs in men and 78758640.6 (75222093.7, 82272935.8) in women. There were 7734064.3 (6744951.2, 8846192) DALYs in men and 7760484.2 (6496609, 9218299.9) in women. Fatal estimates (deaths and YLLs) of NCDs were higher for men, while non-fatal estimates (prevalence, YLDs) were higher for women. Men were superior in all burden indices of NCDs subgroups, except for all indices of DM and YLDs in CVDs. Compared to 1990-2010, the period 2010-2019 confirmed a marked stagnation in decline rates of burden indices, as well as an increase in incidence and prevalence which was more pronounced among men. Despite shrinking sex gaps in NCDs subgroups since 1990, sex gap in DM is widening in 2019.</p><p><strong>Conclusions: </strong>There is a notable sex disparity in NCDs prevalence in Iran, which has become increasingly evident in DM burden. It will be imperative to continue monitoring sexual differences in NCDs burden to determine if disease rates between sexes continue to diverge in the future.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40200-024-01489-1.</p>\",\"PeriodicalId\":15635,\"journal\":{\"name\":\"Journal of Diabetes and Metabolic Disorders\",\"volume\":\"23 2\",\"pages\":\"2207-2224\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-09-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599546/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Diabetes and Metabolic Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s40200-024-01489-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Diabetes and Metabolic Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40200-024-01489-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Sex disparity in the burden of NCDs and its four main subgroups in Iran 1990-2019: a systematic analysis from the global burden of disease study 2019.
Objectives: The significant health differences between sexes in Iran in terms of burden of non-communicable diseases (NCDs) point to the urgency of developing policies. We aim to explore sex disparities in NCDs.
Methods: We used Global Burden of Disease 2019 study to compare estimates of incidence, prevalence, disability-adjusted life years (DALYs), years lived with disabilities (YLDs), years of life lost (YLLs), and deaths among sexes for NCDs, and their main subgroups; neoplasms, cardiovascular diseases (CVDs), chronic respiratory diseases (CRDs), diabetes mellitus (DM) during 1990-2019.
Results: In 2019, there were 62,476,274 (59517167.5, 65759931) incident NCDs in men and 78758640.6 (75222093.7, 82272935.8) in women. There were 7734064.3 (6744951.2, 8846192) DALYs in men and 7760484.2 (6496609, 9218299.9) in women. Fatal estimates (deaths and YLLs) of NCDs were higher for men, while non-fatal estimates (prevalence, YLDs) were higher for women. Men were superior in all burden indices of NCDs subgroups, except for all indices of DM and YLDs in CVDs. Compared to 1990-2010, the period 2010-2019 confirmed a marked stagnation in decline rates of burden indices, as well as an increase in incidence and prevalence which was more pronounced among men. Despite shrinking sex gaps in NCDs subgroups since 1990, sex gap in DM is widening in 2019.
Conclusions: There is a notable sex disparity in NCDs prevalence in Iran, which has become increasingly evident in DM burden. It will be imperative to continue monitoring sexual differences in NCDs burden to determine if disease rates between sexes continue to diverge in the future.
Supplementary information: The online version contains supplementary material available at 10.1007/s40200-024-01489-1.
期刊介绍:
Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.