Journal of Comparative Neurology最新文献

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148077873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Additional Cover: Cover Image, Volume 534, Issue 4","authors":"Margaux Sivori,&nbsp;Bowen Dempsey,&nbsp;Jean-François Brunet","doi":"10.1002/cne.70160","DOIUrl":"https://doi.org/10.1002/cne.70160","url":null,"abstract":"<p>The cover image is based on the Review <i>Little Known Facts, Controversies and Misconceptions About Cranial Motor Nuclei (and a New Classification for All Motoneurons, Cranial, and Spinal)</i> by Margaux Sivori et al., https://doi.org/10.1002/cne.70153.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cne.70160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148076619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148078866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fiber Track Length Gradients in the Avian Sound Localization Circuit Require Conduction Velocity Gradients to Maintain Isochronicity","authors":"David M. Harris","doi":"10.1002/cne.70162","DOIUrl":"10.1002/cne.70162","url":null,"abstract":"<p>The chicken brainstem sound localization neural network exhibits a case where fiber length varies continuously across the fiber arrays connecting n. magnocellularis and n. laminaris. Detailed morphometric measurements were taken to quantify these length gradients. For both ipsilateral and contralateral projections, the path lengths connecting the caudal low-frequency segments are longer than those at the rostral high-frequency end, with a linear path length gradient between them. The length and the length gradient of the contralateral projection increase from hatchling to 2–4 weeks. Synchronous transmission of information is achieved if there is a conduction velocity gradient across both the ipsilateral and contralateral fiber tracts. Adjustments of conduction velocity are required at both the cellular and population levels. A model is proposed that balances conduction distances and velocities by varying the number of nodes of Ranvier along a gradient to achieve isochronicity across the entire network. Continued differential growth between fiber arrays requires a continuous timing adjustment during development and maturation. Control is assigned to the oligodendrocytes that produce and maintain myelin.</p>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13079246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroendocrine Control of the Testis: Focus on Orexinergic Modulation of Spermatogenesis","authors":"Debarshi Sarkar,&nbsp;Deepanshu Joshi,&nbsp;Jyoti Parkash,&nbsp;Shio Kumar Singh","doi":"10.1002/cne.70158","DOIUrl":"10.1002/cne.70158","url":null,"abstract":"<div>\u0000 \u0000 <p>Orexins are hypothalamic neuropeptides that play an essential role in managing the sleep–wake cycle, food intake, and energy balance. There are two forms of orexins, namely orexin A (OXA) and orexin B (OXB). Orexins exert their effects through two different G-protein-coupled receptors (OX1R and OX2R). Apart from the hypothalamus, expressions of orexins and their receptors are also reported in peripheral organs including the testis, prostate, epididymis, seminal vesicle, and penis. Several studies have explored the mechanisms of action of orexin in the male gonad. This review article summarizes recent knowledge on how the orexin system regulates testicular functions like steroidogenesis, germ cell dynamics, glucose metabolism, and oxidative stress responses. By elucidating these mechanisms, the present study may prove helpful in a better understanding of the spermatogenic process. Additionally, this review article may provide new insights into the interaction of the hypothalamus with the testis and the auto/paracrine role of various neuropeptides in the regulation of male reproduction.</p>\u0000 </div>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Little Known Facts, Controversies and Misconceptions About Cranial Motor Nuclei (and a New Classification for All Motoneurons, Cranial, and Spinal)","authors":"Margaux Sivori,&nbsp;Bowen Dempsey,&nbsp;Jean-François Brunet","doi":"10.1002/cne.70153","DOIUrl":"10.1002/cne.70153","url":null,"abstract":"<p>Cranial nerves represent a notoriously complex province of the neuroanatomical landscape of the vertebrates. Here, we offer a selection of the anatomic, genetic, and developmental features of their efferent component that are often misrepresented, ignored or controversial, as a complement to more exhaustive treatments of the subject. Our description reveals that efferent (or “motor”) neurons in vertebrates represent a vague anatomic category (such as that of interneurons) rather than a true neuron type; That motor neurons fall into three bona fide types, segregated on the rostro-caudal axis of the central nervous system; That each of the three types is highly related to a type of preganglionic autonomic neuron; and that this genetic and topographical arrangement of three motor/preganglionic types correlates, not perfectly yet remarkably, with three broad physiological functions.</p>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148078865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148078867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nps-Expressing Neurons Receive Extensive Input From Auditory Brainstem Nuclei","authors":"Richie Zhang,&nbsp;Silvia Gasparini,&nbsp;Joel C. Geerling","doi":"10.1002/cne.70156","DOIUrl":"10.1002/cne.70156","url":null,"abstract":"<p>Neurons that express <i>Nps</i> send output to brain regions implicated in circadian function and threat responses, but less is known about the afferent control of these neurons. In this study, we used a sensitive retrograde tracer, cholera toxin beta subunit (CTb), to identify afferents to the rostral–lateral parabrachial region that contains the main concentration of <i>Nps</i>-expressing neurons. We then used Cre-dependent rabies retrograde tracing in <i>Nps</i>-2A-Cre mice to identify inputs to <i>Nps</i>-expressing neurons within this region. These neurons receive heavy input from auditory brainstem structures, including the inferior colliculus, ventral nucleus of the lateral lemniscus, superior olivary complex, and cochlear nucleus. Due to a discrepancy between sparse rabies and prominent CTb labeling extending from the ipsilateral insular to auditory areas of the cerebral cortex, we also performed anterograde labeling and found many close contacts between cortical boutons and <i>Nps-</i>expressing neurons. These findings suggest an unexpected role for auditory information in controlling the activity of <i>Nps-</i>expressing neurons and add to existing evidence suggesting that rabies is relatively insensitive to retrograde labeling of cortical afferents.</p>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immature Excitatory Neurons in the Postnatal Ferret Paralaminar Nuclei and Their Relationship to the Amygdala Across Species","authors":"Lucía Inés Torrijos-Saiz,&nbsp;Marco Ghibaudi,&nbsp;Malaz Sharief,&nbsp;Lovisa Ljungqvist Brinson,&nbsp;Arturo Alvarez-Buylla,&nbsp;José Manuel García-Verdugo,&nbsp;Vicente Herranz-Pérez,&nbsp;Shawn Sorrells","doi":"10.1002/cne.70155","DOIUrl":"10.1002/cne.70155","url":null,"abstract":"<p>The amygdala paralaminar nuclei (PL) contain immature excitatory neurons that develop on a delayed timeline from birth to adulthood and are more prominent in the amygdala of humans and other primates than in rodents. Whether this expansion is linked to brain complexity or is a feature of primates is unknown. We sought to identify the PL in the ferret (<i>Mustela putorius furo</i>), a small, gyrencephalic mammal that does not belong to the primate order. Here, we show that the amygdala of juvenile (P30–P67) and adult ferrets (&gt;1 year) also contains a collection of immature excitatory neurons that express doublecortin (Dcx) and polysialylated neural cell adhesion molecule (Psa-Ncam). Similar to humans and mice, these immature neurons express Tbr1 and CoupTFII, but not FoxP2, which labels neighboring clusters of GABAergic cells in the intercalated nuclei. Ferret PL neurons extend into the ventral basolateral amygdala (BLA) and appear either in dense clusters surrounded by astroglia or as individual cells, and each subpopulation contains neurons with migratory morphology. This expansion of PL neurons into the amygdala is similar to what is seen in humans, but unlike in mice, where PL neurons are infrequent in the BLA. We compared these findings to the marmoset (<i>Callithrix jacchus</i>), a lissencephalic non-human primate, and the swine (<i>Sus scrofa domesticus</i>), a gyrencephalic mammal, and found immature neurons extending into the amygdala in both. Our study identifies the PL region of the ferret amygdala, which contains immature neurons with migratory features in juveniles and adults. Cross-species comparisons indicate that the expansion of PL neurons into the amygdala seen in primates with both high and low gyrencephalic indices has also occurred in species with gyrencephalic brains from different orders.</p>","PeriodicalId":15552,"journal":{"name":"Journal of Comparative Neurology","volume":"534 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}