Pablo Cure, Joshua P Fessel, Christopher M Hartshorn, Scott J Steele
{"title":"Advancing regulatory science through real-world data and real-world evidence.","authors":"Pablo Cure, Joshua P Fessel, Christopher M Hartshorn, Scott J Steele","doi":"10.1017/cts.2024.501","DOIUrl":"10.1017/cts.2024.501","url":null,"abstract":"","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e87"},"PeriodicalIF":2.6,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael E Bales, Jifeng Zhu, Christine A Ganzer, Farid Aboharb, Allegra Keeler, Krista A Ryon, Brett J Ehrmann, Julianne Imperato-McGinley
{"title":"A retrospective case study of successful translational research: Cardiovascular disease risk assessment, experiences in community engagement.","authors":"Michael E Bales, Jifeng Zhu, Christine A Ganzer, Farid Aboharb, Allegra Keeler, Krista A Ryon, Brett J Ehrmann, Julianne Imperato-McGinley","doi":"10.1017/cts.2024.529","DOIUrl":"10.1017/cts.2024.529","url":null,"abstract":"<p><p>In underserved communities across New York City, uninsured adults encounter a greater risk of cardiovascular disease (CVD) and diabetes. The Heart-to-Heart Community Outreach Program (H2H) addresses these disparities by screening for CVD risk factors, identifying healthcare access barriers, and fostering community engagement in translational research at the Weill Cornell Medicine Clinical and Translational Science Award (CTSA) hub. Screening events are hosted in partnership with faith-based institutions. Participants provide a medical history, complete a survey, and receive counseling by clinicians with referrals for follow-up care. This study aims to quantify H2H screening participant health status; identify socioeconomic, health access, and health-related barriers disproportionately promoting the onset of CVD and diabetes; and develop long-term community partnerships to enable underserved communities to influence activities across the translational research spectrum at our CTSA hub. The population served is disproportionately non-white, and uninsured, with many low-income and underserved individuals. The program was developed in partnership with our Community Advisory Board to empower this cohort to make beneficial lifestyle changes. Leveraging partnerships with faith-based institutions and community centers in at-risk New York City neighborhoods, H2H addresses the increasing burden of diabetes and CVD risk factors in vulnerable individuals while promoting community involvement in CTSA activities, serving as a model for similar initiatives.</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e84"},"PeriodicalIF":2.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: 289 Trailblazer Pilot Grants as Originators of Research Collaborators: Past, Present, and Future - CORRIGENDUM.","authors":"Sarah Mejia Glock, Silvia M Bigatti","doi":"10.1017/cts.2024.541","DOIUrl":"https://doi.org/10.1017/cts.2024.541","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.265.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e85"},"PeriodicalIF":2.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caesar Thompson, Emily Stiehl, Mark Dworkin, Nadine Peacock, Naseem Parsa, Melissa Martin, Cornelius Chandler, Diana Ghebenei, Jennifer Hebert-Beirne
{"title":"Erratum: 292 Activating community health workers: A community-academic partnership to understand vaccine hesitancy - CORRIGENDUM.","authors":"Caesar Thompson, Emily Stiehl, Mark Dworkin, Nadine Peacock, Naseem Parsa, Melissa Martin, Cornelius Chandler, Diana Ghebenei, Jennifer Hebert-Beirne","doi":"10.1017/cts.2024.538","DOIUrl":"https://doi.org/10.1017/cts.2024.538","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.267.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e83"},"PeriodicalIF":2.6,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11091917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra Tilmon, Sharmilee Nyenhuis, Anthony Solomonides, Bruno Barbarioli, Ankur Bhargava, Suzi Birz, Kathryn Bouzein, Celine Cardenas, Bradley Carlson, Ellen Cohen, Emily Dillon, Brian Furner, Zhong Huang, Julie Johnson, Nivedha Krishnan, Kevin Lazenby, Kaitlyn Li, Sonya Makhni, Doriane Miller, Jonathan Ozik, Carlos Santos, Marc Sleiman, Julian Solway, Sanjay Krishnan, Samuel Volchenbouma
{"title":"Erratum: Sociome Data Commons: A scalable and sustainable platform for investigating the full social context and determinants of health - ERRATUM.","authors":"Sandra Tilmon, Sharmilee Nyenhuis, Anthony Solomonides, Bruno Barbarioli, Ankur Bhargava, Suzi Birz, Kathryn Bouzein, Celine Cardenas, Bradley Carlson, Ellen Cohen, Emily Dillon, Brian Furner, Zhong Huang, Julie Johnson, Nivedha Krishnan, Kevin Lazenby, Kaitlyn Li, Sonya Makhni, Doriane Miller, Jonathan Ozik, Carlos Santos, Marc Sleiman, Julian Solway, Sanjay Krishnan, Samuel Volchenbouma","doi":"10.1017/cts.2024.537","DOIUrl":"10.1017/cts.2024.537","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2023.670.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e82"},"PeriodicalIF":2.6,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11091915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Corey McGee, Halil Ibrahim Ergen, Paula Ludewig, Ann Brearley, Ann Van Heest, Erin Krebs
{"title":"Erratum: 404 Mechanisms of a Dynamic Stability Protocol for Persons with Thumb Osteoarthritis - CORRIGENDUM.","authors":"Corey McGee, Halil Ibrahim Ergen, Paula Ludewig, Ann Brearley, Ann Van Heest, Erin Krebs","doi":"10.1017/cts.2024.528","DOIUrl":"https://doi.org/10.1017/cts.2024.528","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.351.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e76"},"PeriodicalIF":2.6,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11091916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Piring, Jim Morrison, Noah Federman, Laurie Shaker-Irwin, Sam Duong-Brett
{"title":"Erratum: 120 Impact of Undergraduate Clinical Research Experience: Highlighting the UCLA Clinical and Translational Science Institute Research Associates Program (CTSI-RAP) - CORRIGENDUM.","authors":"Amanda Piring, Jim Morrison, Noah Federman, Laurie Shaker-Irwin, Sam Duong-Brett","doi":"10.1017/cts.2024.523","DOIUrl":"10.1017/cts.2024.523","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.117.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e68"},"PeriodicalIF":2.1,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11058573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: 313 Data-Driven Evaluation of Community Health Worker Program - CORRIGENDUM.","authors":"Roselyne Tchoua, Kate Karam, Kelly McCabe","doi":"10.1017/cts.2024.522","DOIUrl":"https://doi.org/10.1017/cts.2024.522","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.284.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e70"},"PeriodicalIF":2.6,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11058572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Andrew Lichlyter, Myles Joshua T Tan, Alfredo B Satriya, Weston J Schrock, Shaira L Kee, Michael Aaron G Sy, Mayra B Silva, Trevor L Schrock
{"title":"Erratum: 541 A Framework for Multicultural and Multidisciplinary Near-Peer Mentoring for Artificial Intelligence in Healthcare Education: A University of Florida Friend Group - CORRIGENDUM.","authors":"Daniel Andrew Lichlyter, Myles Joshua T Tan, Alfredo B Satriya, Weston J Schrock, Shaira L Kee, Michael Aaron G Sy, Mayra B Silva, Trevor L Schrock","doi":"10.1017/cts.2024.520","DOIUrl":"https://doi.org/10.1017/cts.2024.520","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1017/cts.2024.462.].</p>","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"8 1","pages":"e69"},"PeriodicalIF":2.6,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11058575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"313 Identification of novel plasma protein of Community Health Worker Program","authors":"Roselyne Tchoua, Kate Karam, Kelly McCabe","doi":"10.1017/cts.2024.284","DOIUrl":"https://doi.org/10.1017/cts.2024.284","url":null,"abstract":"OBJECTIVES/GOALS: Thiswork is an evidential study that demonstrates the positive impactof integrating Community Health Workers (CHWs) and SocialDeterminants of Health on an important health outcome, notably in decreasing the 30-day unplanned hospital ED readmissions at Sinai Health Systems. METHODS/STUDY POPULATION: Using datafrom the Sinai Urban Health Institute (SUHI), we compare predictingthe readmissions of patients with and without data pertainingto Social Determinants of Health (SDoH). We thoroughly describe the data cleaning and data pre-processing, done in collaboration with experts in community health. We use a fundamental and ubiquitous classifier in Random Forest for its feature characterization capability in order to translate models results into insights and recommendations for the CHW program. RESULTS/ANTICIPATED RESULTS: We show that when patients are simply engaged byCHWs, regardless of the content of those conversations, we canincrease the predictive accuracy of our classifier by 5%. We usethis result to make recommendations for improving patient careand discuss limitations and future work. Importantly our workpoints directly to the human connection between patients andCHWs as an important feature in the readmission rate. DISCUSSION/SIGNIFICANCE: Our work shows that the predictive capabilities of the classifier increases with CHW logs and SDoH survey data, highlighting the benefit of collecting this information. This is the first step in early identification of such patients so that CHWs are focusing on and providing resources to patients who will most benefit from the program.","PeriodicalId":15529,"journal":{"name":"Journal of Clinical and Translational Science","volume":"13 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140581152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}