Journal of Clinical Neurophysiology最新文献

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Rapid EEG Monitoring in Clinical Practice. 快速脑电图监测在临床中的应用。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-03-01 Epub Date: 2025-08-05 DOI: 10.1097/WNP.0000000000001192
Kapil Gururangan, Santiago Philibert-Rosas, Thanujaa Subramaniam
{"title":"Rapid EEG Monitoring in Clinical Practice.","authors":"Kapil Gururangan, Santiago Philibert-Rosas, Thanujaa Subramaniam","doi":"10.1097/WNP.0000000000001192","DOIUrl":"10.1097/WNP.0000000000001192","url":null,"abstract":"<p><strong>Summary: </strong>Rapid electroencephalography (EEG) devices have emerged in response to the growing awareness of seizures and highly epileptiform patterns in critically ill patients and limitations associated with conventional EEG infrastructure. In this review, we describe rapid EEG utilization patterns, clinical workflows, implementation challenges, and financial considerations using a narrative review supplemented by a multi-institutional survey of 20 centers affiliated within the Critical Care EEG Monitoring Research Consortium. We identified that rapid EEG was perceived to expedite diagnosis and treatment decisions and enhance clinical triage, and most respondents perceived the cost of rapid EEG sessions to be low. However, commonly cited limitations included lower spatial resolution and unsuitability for replacing conventional EEG for prolonged monitoring. Prior cohort studies and clinical trials of rapid EEG devices display site-by-site variability in practical workflows regarding specificity of clinical indications for monitoring and designated personnel for device setup and EEG review, however, rapid EEG was reported to consistently augment EEG monitoring capabilities even at centers with access to conventional EEG. Because rapid EEG devices are increasingly adopted, and paired with artificial intelligence tools, it will be vital for institutions to develop protocols and guidelines with multidisciplinary input to steer their responsible, effective, and sustainable use.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":"43 3","pages":"222-227"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Resolution Ultrasonography for Detecting Peripheral Neuropathy in Leprosy: A Systematic Review and Meta-Analysis. 高分辨率超声检查麻风病周围神经病变:系统回顾和荟萃分析。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-03-01 DOI: 10.1097/WNP.0000000000001229
Sara Ahmed Metwally, Shahd Al Haj Ali, Mostafa Tantawy, Nehal Ataky, Karim Mohamed Eltaib, Mohamed Emam Elatrosh, Horiah Amer Al-Ghorbany, Alamin Awadallah Mohamed Magzoub, Baraah Abd-Alqader Ibraheem Mdalal, Ahmed Medhat Helmy Hussein, Khaled Ashraf Mohamed, Mohamed A Bedewi, Ezzat M Awad
{"title":"High-Resolution Ultrasonography for Detecting Peripheral Neuropathy in Leprosy: A Systematic Review and Meta-Analysis.","authors":"Sara Ahmed Metwally, Shahd Al Haj Ali, Mostafa Tantawy, Nehal Ataky, Karim Mohamed Eltaib, Mohamed Emam Elatrosh, Horiah Amer Al-Ghorbany, Alamin Awadallah Mohamed Magzoub, Baraah Abd-Alqader Ibraheem Mdalal, Ahmed Medhat Helmy Hussein, Khaled Ashraf Mohamed, Mohamed A Bedewi, Ezzat M Awad","doi":"10.1097/WNP.0000000000001229","DOIUrl":"10.1097/WNP.0000000000001229","url":null,"abstract":"<p><strong>Background: </strong>Leprosy is a chronic granulomatous disease that commonly affects the peripheral nervous system, often leading to significant disability. High-resolution ultrasonography has emerged as a promising tool for the noninvasive assessment of nerve involvement in leprosy.</p><p><strong>Objective: </strong>To figure out the diagnostic value of HRUS in assessing peripheral nerve involvement in leprosy, with a focus on measuring the cross-sectional area (CSA) of major nerves.</p><p><strong>Methods: </strong>A systematic search of PubMed, Scopus, Web of Science, and Embase was conducted up to 2024. Seventeen studies were included, and quality assessment was performed using NIH and NOS tools. Meta-analyses compared CSA of the ulnar, median, posterior tibial, and common fibular nerves between patients with leprosy and healthy controls. Heterogeneity was evaluated using the I2 statistic and sensitivity analyses were performed.</p><p><strong>Results: </strong>Patients with leprosy showed significantly increased CSA in all examined nerves compared with controls. Single-arm analysis of CSA in patients with leprosy showed consistent nerve enlargement, particularly in the ulnar nerve.</p><p><strong>Conclusions: </strong>Our review shows the usefulness of HRUS as a sensitive, noninvasive imaging modality for evaluating peripheral nerve involvement in leprosy.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":"43 3","pages":"228-236"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid-EEG Technologies in Comprehensive Neuromonitoring. 快速脑电图技术在综合神经监测中的应用。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-03-01 DOI: 10.1097/WNP.0000000000001245
Mariel Kalkach-Aparicio, Aaron F Struck
{"title":"Rapid-EEG Technologies in Comprehensive Neuromonitoring.","authors":"Mariel Kalkach-Aparicio, Aaron F Struck","doi":"10.1097/WNP.0000000000001245","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001245","url":null,"abstract":"","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":"43 3","pages":"189-190"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends and Demographic Disparities in the Utilization of Intraoperative Neuromonitoring in the United States, 2008 to 2021. 2008年至2021年美国术中神经监测应用的趋势和人口统计学差异
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-03-01 Epub Date: 2025-07-02 DOI: 10.1097/WNP.0000000000001187
Ali Al-Salahat, Danielle B Dilsaver, Yu-Ting Chen, Rohan Sharma, Nidhi Kapoor, Evanthia Bernitsas
{"title":"Trends and Demographic Disparities in the Utilization of Intraoperative Neuromonitoring in the United States, 2008 to 2021.","authors":"Ali Al-Salahat, Danielle B Dilsaver, Yu-Ting Chen, Rohan Sharma, Nidhi Kapoor, Evanthia Bernitsas","doi":"10.1097/WNP.0000000000001187","DOIUrl":"10.1097/WNP.0000000000001187","url":null,"abstract":"<p><strong>Purpose: </strong>Intraoperative neuromonitoring (IONM) is a valuable tool to monitor the neural axis during various procedures and guide intervention aimed at managing operative complications. The literature lacks large scale data on trends and demographic disparities in IONM use in the United States.</p><p><strong>Methods: </strong>Data were abstracted from the 2008-2021 National Inpatient Sample. Hospitalizations for neurosurgical (spinal, craniotomy, carotid artery, cranial/peripheral nerve), cardiac/vascular, and head/neck/thyroid procedures were identified and stratified by IONM use. Logistic regression models were estimated to assess disparities and trends in IONM use. Multivariable models adjusted for patient- and facility-level characteristics.</p><p><strong>Results: </strong>From 2008 to 2021, the rate of IONM use increased significantly in neurosurgical (3.69% to 18.62%, p < 0.001) and cardiac/vascular procedures (0.018% to 0.6%, p < 0.001). IONM use for head/neck/thyroid procedures increased steadily until 2014 and then declined ( p < 0.001). Compared with hospitalizations of White patients, Black (aOR = 0.87, 95% CI: 0.81-0.94) and Hispanic (aOR = 0.88, 95% CI: 0.81-0.96) patients were associated with lower odds of IONM use during craniotomy. Lower incomes (0-25th quartile) were associated with lower odds of IONM use in both spinal (aOR = 0.83, 95% CI: 0.78-0.88) and craniotomy procedures (aOR = 0.78, 95% CI: 0.72-0.85).</p><p><strong>Conclusions: </strong>There is a growing demand for IONM to enhance the safety of various procedures, indicating a need for neurologists and technologists with this expertise. In addition, we found significant racial/ethnic and socioeconomic disparities in IONM use. These findings can be valuable for health care administrators and policymakers to address disparities in the access to IONM.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":"267-275"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Auditory Reaction Time in People With Epilepsy and Healthy Controls. 癫痫患者和健康对照者的听觉反应时间
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-03-01 Epub Date: 2025-09-03 DOI: 10.1097/WNP.0000000000001202
Nora Schwab, Roland Renzel, Murezi Capaul, Pascal Luc Faber, Tena Dubcek, Lukas Imbach, Debora Ledergerber
{"title":"Auditory Reaction Time in People With Epilepsy and Healthy Controls.","authors":"Nora Schwab, Roland Renzel, Murezi Capaul, Pascal Luc Faber, Tena Dubcek, Lukas Imbach, Debora Ledergerber","doi":"10.1097/WNP.0000000000001202","DOIUrl":"10.1097/WNP.0000000000001202","url":null,"abstract":"<p><strong>Objective: </strong>Simple reaction time (SRT) to acoustic stimuli is a typical parameter used in the assessment of driving ability in people with epilepsy (PWE). In clinical practice, auditory SRT is commonly compared during and outside of epileptiform discharges (ED). Yet, a subset of PWE also has slowed SRT outside their ED, possibly because of antiseizure medication (ASM) or disease-associated network alterations. SRT values should therefore be compared with reference values from matched controls which are currently lacking in practice. We here aimed to find a reference range of SRT in healthy controls using the same paradigm as commonly used in PWE.</p><p><strong>Methods: </strong>We measured auditory SRT in heathy control subjects without epilepsy and a cohort of patients with epilepsy. We matched the control cohort, according to age and sex, to a cohort of PWE who had previously been recorded at our center using the same task. This allowed to compare auditory SRT between a control cohort and a cohort of PWE.</p><p><strong>Results: </strong>The control group showed a significantly lower mean SRT latency and a smaller SRT variability as compared with PWE. Within the cohort of PWE, the SRT was significantly prolonged during periods with ED. Potential confounding factors, such as age, did not show any significant contribution to auditory SRT.</p><p><strong>Conclusions: </strong>Our findings demonstrate a small intrapersonal variance of SRT in the control group. Therefore, outlier SRT values in PWE during ED are likely a useful parameter for assessing driving ability.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":"259-266"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144956193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcortical Stimulation for Functional Brain Mapping: A Systematic Review. 皮层下刺激对脑功能映射的系统评价。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-02-23 DOI: 10.1097/WNP.0000000000001246
Adrian Safa, David Sabsevitz, Marco Failla Mulone, Anteneh M Feyissa, Seyed M Mirsattari, Ipshita Garg, Rena Wolf, Phillip Gauthier, Kaisorn Chaichana, Sanjeet S Grewal, Victoria Clark, Richard Byrne, Alfredo Quinones-Hinojosa, William O Tatum, Brin E Freund
{"title":"Subcortical Stimulation for Functional Brain Mapping: A Systematic Review.","authors":"Adrian Safa, David Sabsevitz, Marco Failla Mulone, Anteneh M Feyissa, Seyed M Mirsattari, Ipshita Garg, Rena Wolf, Phillip Gauthier, Kaisorn Chaichana, Sanjeet S Grewal, Victoria Clark, Richard Byrne, Alfredo Quinones-Hinojosa, William O Tatum, Brin E Freund","doi":"10.1097/WNP.0000000000001246","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001246","url":null,"abstract":"<p><strong>Purpose: </strong>Subcortical functional brain mapping is a valuable technique, especially involving lesions within or near white matter tracts. Motor and language deficits caused by intraoperative damage to these subcortical fibers are associated with worse outcomes. However, there are variable approaches to performing subcortical functional brain mapping. This systematic review was performed to better understand indications and optimal stimulation parameters.</p><p><strong>Methods: </strong>A systematic review was performed by PRISMA guidelines, using PubMed, Scopus, and Medline databases. Search dates ranged from inception to November 30th, 2024. Studies included adults who underwent subcortical electrical stimulation for functional brain mapping.</p><p><strong>Results: </strong>A total of 55 articles (249 patients, mean age 44.8 years, 114 female) were included. The most common pathology was brain tumor (96.3%), primarily gliomas and metastases, and 24.4% of all cases had a history of epilepsy. The most frequently mapped white matter tracts were the arcuate fasciculus, corticospinal/pyramidal tract, and inferior fronto-occipital fasciculus, involving motor, language, and cognitive functions. Bipolar stimulation (50-60 Hz, 0.5-1 millisecond, 1-10 mA) was preferred over monopolar stimulation. Among 147 patients with outcome data, 89.1% did not suffer permanent adverse outcomes including neurologic deficits, although long-term outcomes were inconsistently reported.</p><p><strong>Conclusions: </strong>The methodologic variability of subcortical functional brain mapping and lack of long-term follow-up reported limits determination of optimal parameter selection for electrical stimulation although common trends are reported. Functional brain mapping approaches may be guided by the tract and network involved. Further studies are needed to develop a standardized approach and more definitive guideline to its performance.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147290230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of Automated Detection Software in Absence Seizures. 自动检测软件在失神发作中的表现。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-02-19 DOI: 10.1097/WNP.0000000000001242
Elisabeth E M Reus, Anna P van der Vloed, Robert M Helling, Gerhard H Visser, Fieke Cox
{"title":"Performance of Automated Detection Software in Absence Seizures.","authors":"Elisabeth E M Reus, Anna P van der Vloed, Robert M Helling, Gerhard H Visser, Fieke Cox","doi":"10.1097/WNP.0000000000001242","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001242","url":null,"abstract":"<p><strong>Purpose: </strong>Absence seizures are common in children with idiopathic generalized epilepsies. Identifying absence seizures in EEG using automated detection software offers potential efficiency gain.</p><p><strong>Methods: </strong>This study assessed Persyst's performance in detecting absence seizures (≥3 seconds) in prolonged pediatric EEGs. Two detection modules were used: seizure detection (most sensitive settings) and spikeburst detection which detects 'bursts' of interictal epileptiform discharges (≥1 spike per second) with a minimal duration of 1, 2 or 3 seconds.</p><p><strong>Results: </strong>Eighty-one EEG records from 69 patients were analyzed. Seizure detections sensitivity is 78%, spikebursts sensitivity is 95% (1 second), 77% (2 seconds) and 61% (3 seconds). Detection rate of both modules increased to 99% for absences lasting more than 9 seconds. Median false positive rates are 24 per 24 hours (range 0-60) for seizure detection and 23 (range 0-293), one (range 0-36) and zero (range 0-19) for the spikeburst module with duration of respectively 1, 2 or 3 seconds, primarily due to interictal discharges.</p><p><strong>Conclusion: </strong>Spikeburst module with a threshold duration of 2 seconds represents the most feasible compromise between sensitivity and clinical usability.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yield of Hyperventilation and Other Activation Procedures and Study Parameters in Facilitating Epileptiform Discharges. 促进癫痫样放电的过度通气和其他激活程序的量和研究参数。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-02-18 DOI: 10.1097/WNP.0000000000001244
Kelly A Denhard, Mark Quigg, Erika T Axeen
{"title":"Yield of Hyperventilation and Other Activation Procedures and Study Parameters in Facilitating Epileptiform Discharges.","authors":"Kelly A Denhard, Mark Quigg, Erika T Axeen","doi":"10.1097/WNP.0000000000001244","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001244","url":null,"abstract":"<p><strong>Purpose: </strong>Hyperventilation (HV) during EEG was restricted during the COVID-19 pandemic. The authors compared EEGs with and without HV to place HV in context of other factors that precipitate epileptiform abnormalities (EA). The authors hypothesized HV would not significantly affect the sensitivity of routine EEG in children and adults.</p><p><strong>Methods: </strong>The authors reviewed routine EEGs completed between March 2018 and March 2022 in subjects older than 4 years. The primary outcome variable was EA (seizures and epileptiform discharges). In a subset of patients with serial EEGs with and without HV, the authors compared intrasubject appearance of EA (McNemar test). The authors then evaluated regression models with the outcome of EA (present or absent) against independent variables of HV, EEG duration, photic stimulation, sleep deprivation, sleep, and patient-related variables of age, sex, and anti-seizure medication burden.</p><p><strong>Results: </strong>Of 659 patients (806 EEGs), 180 had EA (27%). No adults had HV-activated EA. 64 of 659 patients (9.7%) had repeated EEGs both with and without HV; 34 of these (53%) had EA with HV, and 26 (41%) had EA without HV (P = 0.077, McNemar test). anti-seizure medication burden, longer recording, and HV all had significant positive odds ratios on the prevalence of EA. Sleep deprivation had a positive nonsignificant odds ratio.</p><p><strong>Conclusions: </strong>Sleep deprivation, longer recording, and HV favored EA after accounting for age and epilepsy severity. Because no adults had EA with HV, the findings suggest that HV in adults can be an elective activation procedure during EEG; sleep deprivation and longer duration recordings, in contrast, provide increased yields of EA.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring Reinnervation and Neuroplasticity After Neurotization Using Needle Electromyography. 针刺肌电图监测神经化后神经再生和神经可塑性。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-02-12 DOI: 10.1097/WNP.0000000000001243
Štěpánka Brušáková, Ivan Humhej, Jan Lodin, Jiří Ceé, Irena Holečková
{"title":"Monitoring Reinnervation and Neuroplasticity After Neurotization Using Needle Electromyography.","authors":"Štěpánka Brušáková, Ivan Humhej, Jan Lodin, Jiří Ceé, Irena Holečková","doi":"10.1097/WNP.0000000000001243","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001243","url":null,"abstract":"<p><strong>Purpose: </strong>Brachial plexus injuries show variable outcomes after nerve transfer surgery. Recovery depends not only on axonal regeneration but also on cortical plasticity. Although neuroimaging can detect such changes, its clinical utility is limited. Needle electromyography offers a reproducible, low-cost method to assess reinnervation and synkinetic activity as potential markers of neuroplasticity.</p><p><strong>Methods: </strong>We conducted a longitudinal observational study of 21 patients who underwent 34 proximal nerve transfers (2012-2020) to restore shoulder and elbow function after traumatic brachial plexus injury. Serial electromyography was performed at 3- to 9-month intervals over ≥36 months, using dual-channel recordings to assess spontaneous activity, motor unit potentials, and synkineses. Functional outcomes were measured using the MRC scale, goniometry, modified Mallet scale, and DASH questionnaire.</p><p><strong>Results: </strong>Mean age was 36.1 years; 86% were male. Root avulsions occurred in 43%, panavulsion in 10%. Median time from trauma to surgery was 147 days. Functional success (MRC ≥3/5 with adequate ROM) was achieved in 58.8% of transfers. Early reinnervation (<6 months) occurred in 53% and correlated with greater muscle strength (Rs = 0.53, p < 0.01). Synkineses resolution occurred in 29% and correlated negatively with time to surgery (Rs = -0.50, p = 0.005). Absence of synkineses was associated with better outcomes (60 vs. 40%, p = 0.07).</p><p><strong>Conclusions: </strong>Needle electromyography enables systematic, accessible tracking of reinnervation and synkineses. Resolution of synkineses may indicate functional cortical reorganization and support improved recovery. This approach warrants further prospective validation.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal Intraoperative Neurophysiologic Monitoring Including Transcranial Motor Evoked Potentials for the Detection of Cerebral Ischemia During Carotid Endarterectomy. 多模态术中神经生理监测包括经颅运动诱发电位检测颈动脉内膜切除术中脑缺血。
IF 1.7 4区 医学
Journal of Clinical Neurophysiology Pub Date : 2026-02-04 DOI: 10.1097/WNP.0000000000001241
Rohit Gummi, Thomas Hirschauer, Felix Chang, Ankita Tippur, Mark Keroles, Nick Meyers, Viet Nguyen, Leslie Lee, S Charles Cho, Jaime R López, Scheherazade Le
{"title":"Multimodal Intraoperative Neurophysiologic Monitoring Including Transcranial Motor Evoked Potentials for the Detection of Cerebral Ischemia During Carotid Endarterectomy.","authors":"Rohit Gummi, Thomas Hirschauer, Felix Chang, Ankita Tippur, Mark Keroles, Nick Meyers, Viet Nguyen, Leslie Lee, S Charles Cho, Jaime R López, Scheherazade Le","doi":"10.1097/WNP.0000000000001241","DOIUrl":"https://doi.org/10.1097/WNP.0000000000001241","url":null,"abstract":"<p><strong>Purpose: </strong>Carotid endarterectomy (CEA) is a common surgical intervention, but the perioperative stroke risk may be as high as 12%, with an average reported rate approximately 3%. Intraoperative neurophysiologic monitoring (IONM) can provide real-time feedback to guide the surgical team on whether or not to place a temporary shunt to reduce the length of time that cerebral blood flow is interrupted. In this study, the authors assessed the utility of adding transcranial motor evoked potentials (tcMEPs) to other IONM modalities in early detection of cerebral ischemia during CEAs.</p><p><strong>Methods: </strong>The authors conducted a retrospective review of CEA cases from 2010 to 2020 at this center and included all CEA cases with electroencephalogram (EEG), somatosensory evoked potentials (SSEPs) and tcMEPs. The authors analyzed the IONM reports for case details. The primary study end points were types of IONM changes and their relative onsets to carotid occlusion.</p><p><strong>Results: </strong>The authors identified 254 patients who underwent 274 CEAs using multimodal IONM. In 35 (12.7%) cases, there were critical IONM changes with 33 (12.0%) demonstrating changes during clamping of the carotid artery. Of these 35 cases, changes in both SSEPs and tcMEPs were observed in 20 (57.1%), only SSEP changes in 8 (22.9%), and only tcMEP changes in 2 (5.7%). In 5 cases, tcMEP loss was noted to precede other IONM changes. In total, 82% of significant changes were observed within the first 10 minutes of carotid clamping.</p><p><strong>Conclusions: </strong>This large cohort study shows that multimodal IONM with tcMEPs can contribute to the early detection of cerebral ischemia during CEA.</p>","PeriodicalId":15516,"journal":{"name":"Journal of Clinical Neurophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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