Christoph S Dietze, Dieke van Waart-Houtman, Anne Marthe Meppelink, Mireille Bourez-Swart, Job van der Palen, Maeike Zijlmans, Sandra M A van der Salm
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引用次数: 0
摘要
目的：功能性运动障碍患者的Bereitschaftspotential（BP）或准备电位有助于诊断工作。我们评估了 BP 作为功能性癫痫发作（FS）患者发作间期脑电图标记的诊断价值：我们记录并分析了 17 名成人功能性癫痫患者和 17 名有其他诊断的对照组患者在意图运动前的发作间期脑电图。我们评估了 BP 的存在、潜伏期、振幅以及早期与晚期 BP 的信号：结果：除一名 FS 患者外，其他所有患者都出现了 Bereitschaftspotential。我们发现，FS 患者与对照组患者在 BP 的潜伏期和振幅方面没有明显差异。早期 BP 在振幅、潜伏期和存在性方面的差异最大：结论：我们发现 FS 患者发作间期的典型 BP 值和可变的半身像，而早期研究发现功能性运动障碍患者发作间期无 BP。这些发现并不支持将 BP 用作 FS 的发作间期诊断工具。早期血压的差异以及对具有纯运动半身像的FS的关注是进一步研究评估FS患者潜在发作间期标志物的起点。
Diagnostic Value of Bereitschaftspotential in People With Functional Seizures.
Purpose: Bereitschaftspotential (BP) or readiness potential in people with functional movement disorders can aid diagnostic workup. We evaluated the diagnostic value of BP as an interictal EEG marker in people with functional seizures (FS).
Methods: We recorded and analyzed BP interictal before intended movements in 17 adults with FS and 17 controls with alternative diagnoses. We evaluated the signals for the presence of BP, latency, amplitude, and early versus late BP.
Results: Bereitschaftspotential was present in all except one person with FS. We found no significant differences in the latency and amplitude of BP between participants with FS and controls. The early BP showed the most significant variance in amplitude, latency, and presence.
Conclusions: We found interictal typical BP values in participants with FS and variable semiology, while earlier research found interictal no BP in functional movement disorders. These findings do not support the use of BP as an interictal diagnostic tool for FS. Differences in early BP and focus on FS with pure motor semiology are starting points for further research evaluating potential interictal markers in people with FS.
期刊介绍：
The Journal of Clinical Neurophysiology features both topical reviews and original research in both central and peripheral neurophysiology, as related to patient evaluation and treatment.
Official Journal of the American Clinical Neurophysiology Society.
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