{"title":"Evaluation of Oral Appliance Therapy Using a Novel Titration Method for Obstructive Sleep Apnea.","authors":"Yuko Fujii, Naoki Ikehata, Takayuki Nakai, Hidetoshi Takahashi, Kazuki Shiina, Yoichi Araki, Shunichiro Orihara, Akira Matsuo, Daichi Chikazu","doi":"10.1097/SCS.0000000000012018","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012018","url":null,"abstract":"<p><p>The purpose of an oral appliance (OA) is to relieve upper airway obstructions by advancing the mandible. This study evaluated the effectiveness of a new OA fabrication method in which the mandibular position was determined through MRI-based soft tissue assessment. An OA was fabricated using SomGauge (SomnoMed, Inc), and patients who underwent polysomnography at diagnosis (T0) and follow-up (T1) were included. OA response rates were compared between the following 2 groups: the S group, in which the OA was fabricated using the standard method, and the S-MRI (SomGauge-MRI) group, in which fabrication was guided by MRI soft tissue evaluation. Twenty-five patients were enrolled in the S group and 19 in the S-MRI group. No significant differences in age, body mass index (BMI), apnea-hypopnea index (AHI), or mandibular advancement were noted between groups. AHI reduction rates were 44.29%±6.37% in the S group and 65.09%±5.04% in the S-MRI group; hypopnea index reduction rates were 39.10%±7.15% and 62.97%±5.22%, respectively, with both showing significant improvement. No significant difference was found in apnea index reduction rates between the S (58.57%±13.61%) and S-MRI (61.60%±10.33%) groups. The MRI-based mandibular positioning method improved the success rate of OA therapy compared with the conventional approach, supporting its clinical utility in enhancing airway patency in sleep-disordered breathing.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Lin, Xin-Ting Ji, Jing-Yi Wang, Qin Zhang, Zhao-Hui Chen, Ping Li, Yuan-Tao Yang, Guo-Jing Yang, Shui-Hua Wu, Shuo Gu
{"title":"A Novel Noninvasive Screening Method for Early Detection of Sagittal Craniosynostosis Using the Surface Cranial Index.","authors":"Jun Lin, Xin-Ting Ji, Jing-Yi Wang, Qin Zhang, Zhao-Hui Chen, Ping Li, Yuan-Tao Yang, Guo-Jing Yang, Shui-Hua Wu, Shuo Gu","doi":"10.1097/SCS.0000000000011982","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011982","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the diagnostic value of a novel anthropometric parameter, the surface cephalic index (SCI), in the early screening of sagittal craniosynostosis (SC), and to compare its diagnostic performance with that of the traditional cephalic index (CI).</p><p><strong>Methods: </strong>A retrospective case-control study was conducted, involving 54 children diagnosed with SC from June 2015 to September 2022 across three hospitals. A control group of 1350 age-matched children without cranial deformities was selected. SCI and CI were calculated using preoperative CT data and 3-dimensional cranial models reconstructed with Materialise Mimics 26.0 software. Diagnostic performance was assessed using Spearman correlation, logistic regression, receiver operating characteristic (ROC) curves, and McNemar test.</p><p><strong>Results: </strong>Surface cephalic index was significantly negatively correlated with SC (ρ= -0.301, P<0.001). The SCI-based logistic model yielded an AUC of 0.951 (95% CI: 0.922-0.980), with 68.52% sensitivity and 97.63% specificity. Diagnostic accuracy was statistically comparable between SCI and CI (P=0.47). A cutoff value of 77.36% for SCI was established for screening purposes.</p><p><strong>Conclusion: </strong>Surface cephalic index is a newly developed, noninvasive, and radiation-free cranial measurement index that relies solely on external anatomic landmarks. Compared with CI, it eliminates the need for CT imaging, reducing risk and cost while maintaining high diagnostic performance. Its simplicity, accessibility, and safety make SCI a practical tool for early SC screening, particularly in pediatric, primary care, and home settings. It addresses key limitations of CI and holds strong potential for broader clinical application.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelica Meriano, Giulia Amodeo, Paolo Arangio, Flavia La Greca, Domenico Scopelliti
{"title":"3D Printed Custom Made Cutting Guides and Plates for Maxillary Repositioning in Orthognathic Surgery: An Evaluation of the Accuracy of the Results.","authors":"Angelica Meriano, Giulia Amodeo, Paolo Arangio, Flavia La Greca, Domenico Scopelliti","doi":"10.1097/SCS.0000000000012006","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012006","url":null,"abstract":"<p><p>This study evaluates the accuracy of 3D preoperative planning and 3D printed custom cutting guides and plates for maxillary repositioning in orthognathic surgery. A retrospective analysis was conducted on 28 patients treated at our institute between January 2022 and December 2024. All underwent orthognathic surgery with custom cutting guides and plates for the maxilla and bilateral sagittal split osteotomy (BSSO) for the mandible. Inclusion criteria included skeletal class II or III malocclusion, completion of presurgical orthodontics, and 3D planning using ProPlan software. Each patient underwent 3D photography and CBCT at multiple time points, including pre- and postsurgery (6 months). The positions of the A point, the anterior nasal spine (ANS), the posterior nasal spine (PNS), the incisor mid, the right and the left canine, and the right and the left first molar were marked on the 3D program and the post-op CBCT, and the discrepancies were analyzed. For each cephalometric point considered the mean and the SD of the discrepancy values were calculated. The values were also analyzed according to a linear regression model and a t test was conducted. The study confirms high accuracy in maxillary repositioning when using computer-aided planning with customized guides and plates, showing these tools can improve accuracy, efficiency, and outcome prediction.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sedat Özbay, Nuray Bayar Muluk, Tarik Yagci, Volkan Ercan, Engin Özakin, Mustafa Yazir, Abuzer Coskun, Orhan Özsoy, Mustafa Safa Pepele, Erhan Arikan, Gürcan Sünnetci, Erdi Özdemir, Ahmet Arslanoğlu, Moises Gallegos, Cemal Cingi
{"title":"Overview of Etiology and Management of Epistaxis: Through the Mnemonic EPISTAXIS.","authors":"Sedat Özbay, Nuray Bayar Muluk, Tarik Yagci, Volkan Ercan, Engin Özakin, Mustafa Yazir, Abuzer Coskun, Orhan Özsoy, Mustafa Safa Pepele, Erhan Arikan, Gürcan Sünnetci, Erdi Özdemir, Ahmet Arslanoğlu, Moises Gallegos, Cemal Cingi","doi":"10.1097/SCS.0000000000012040","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012040","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the rate of application of various treatment steps for epistaxis using the mnemonic EPISTAXIS.</p><p><strong>Methods: </strong>Two thousand three hundred patients with epistaxis (1284 males and 1016 females) meeting the inclusion criteria from various centers in different regions of Turkey were enrolled in the study. All presented to the Emergency Department with epistaxis. Each patient was evaluated on the following items: cause of the epistaxis, accompanying diseases, and interventions performed (using the EPISTAXIS Mnemonic).</p><p><strong>Results: </strong>Idiopathic epistaxis was found in 80.0% of cases. Other causes included home accidents (7.7%), finger trauma (3.9%), rhinosinusitis (2.8%), and foreign bodies (2.4%). Hypertension was the most commonly detected accompanying condition (39.0%). Other diseases included diabetes mellitus (17.9%), blood disorders related to epistaxis (6.1%), and malignancy (5.9%). Intervention performed (EPISTAXIS Mnemonic) results were as follows:Examination: Anterior epistaxis was detected at 95.0% and posterior epistaxis at 5.0%. Pressure (apply pressure over the nose with fingers) was applied in 48.3%. Irrigation (irrigate with warm water) was performed at 0.52%. Silver nitrate: Cauterization was applied at a concentration of 22.86%. Tampons/nasal pack (anterior or posterior tampon) were applied at 73.86%. Afrin: Vasoconstrictor spray (oxymetazoline spray) was applied to a tampon at 40.34%. Transamine-tranexamic acid-applied on a tampon was performed at 17.0%. Interventional radiology (embolization) was not performed (0.0%). Surgical consultation: ENT consultation was requested at 11.3%.</p><p><strong>Conclusions: </strong>For the treatment of epistaxis, the mnemonic EPISTAXIS (1) is suggested for a proper understanding and recall of appropriate treatment steps.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonographic Imaging Features of Carotid Webs Correlate With the Risk of Stroke.","authors":"Juan Dong, Bo Sun, Dian-Xia Men, Li-Ping Liu","doi":"10.1097/SCS.0000000000011944","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011944","url":null,"abstract":"<p><strong>Objective: </strong>The carotid web has been increasingly recognized as a potential source of thromboembolism in ischemic stroke patients who do not have conventional stroke risk factors. Ultrasound is the most commonly used imaging technique for initial screening. In this study, we aimed to investigate the morphologic characteristics of carotid web and their correlation with stroke using ultrasound.</p><p><strong>Methods: </strong>We retrospectively analyzed carotid ultrasonography data diagnosed with acute ischemic stroke and carotid web between July 2020 and December 2024. The presence of carotid web was confirmed using digital subtraction angiography and carotid ultrasound. Patients were categorized into symptomatic carotid web group or asymptomatic carotid web group based on whether they had an acute ischemic stroke ipsilateral to the carotid web. We compared baseline data and morphologic variables of the carotid webs, including length, thickness, and angle between the 2 groups.</p><p><strong>Results: </strong>A total of 18 carotid webs were identified for this study. Patients in the symptomatic carotid web group had significantly longer webs compared with those in the asymptomatic carotid web group. However, the angle between the carotid web and the carotid wall, as well as the thickness of the carotid web, did not differ significantly between the 2 groups. A carotid web length of ≥3.4 mm was identified as the optimal threshold associated with stroke.</p><p><strong>Conclusions: </strong>Ultrasound is effective in thoroughly delineating the morphologic characteristics of carotid web. Individuals with longer carotid web are more likely to experience acute ischemic stroke.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intracranial Tuberculoma Mimicking Malignant Tumor in a Hemodialysis-Dependent Patient With Multimorbidity: Diagnostic Challenges and Molecular Pathologic Confirmation.","authors":"Senxin Zhang, Yong Zheng","doi":"10.1097/SCS.0000000000012049","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012049","url":null,"abstract":"<p><p>Central nervous system tuberculomas are clinically rare (accounting for 1%-2% of intracranial space-occupying lesions), and they are particularly prone to misdiagnosis as malignant tumors when there is a lack of symptoms of tuberculosis intoxication. This article reports a case of a 39-year-old female who presented with generalized tonic-clonic seizures. Imaging suggested a malignant invasive lesion in the frontal lobe with skull base destruction. The patient had multiple high-risk factors including hemodialysis, diabetes, and anticoagulation after coronary stent placement, and was ultimately diagnosed with intracranial tuberculoma through molecular pathology. This case highlights the insidious nature of extrapulmonary tuberculosis and the diagnostic challenges under the coexistence of multiple diseases, providing a reference for diagnosis in similar complex cases.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ken Yukawa, Mutsumi Okazaki, Koji Kanayama, Kentaro Tanaka, Hiroki Mori, Noriko Uemura
{"title":"Reconstruction of a Moderate Palatal Fistula and Facial Contour in a 61-Year-Old Patient After Cleft Lip and Palate Surgery Using a Free Latissimus Dorsi Muscle Flap Combined With the Scapular Bone.","authors":"Ken Yukawa, Mutsumi Okazaki, Koji Kanayama, Kentaro Tanaka, Hiroki Mori, Noriko Uemura","doi":"10.1097/SCS.0000000000012052","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012052","url":null,"abstract":"<p><p>A 61-year-old female patient with cleft lip and palate presented with a moderate palatal fistula and associated nasal deformity. The defect posed a surgical challenge, being too extensive for local mucosal flap closure, yet too confined to permit standard free flap insertion. Due to the restricted intraoral working space and reduced mucosal vascularity, a latissimus dorsi free muscle flap combined with the scapular bone was chosen for reconstruction. The nasal side of the fistula was closed using a hinge flap, and mucosalization of the muscle occurred spontaneously within 1 month. This novel technique successfully restored the continuity of the maxillary arch, addressed the alar base depression, and provided stable support for dentures. No recurrence was observed during the 1-year follow-up period. This case highlights the utility of a modified free flap approach for anatomically limited palatal fistulas, offering both functional rehabilitation and aesthetic improvement in complex craniofacial conditions.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanxi Gong, Yi Cao, Xuan Han, Huachang Sun, Jiaxin Li, Yongsheng Tang, Chao Xu
{"title":"Clinical Efficacy of V-Y Subcutaneous Pedicle Flap and Modified Rhomboid Flap in Defect Repair After Facial Tumor Resection.","authors":"Yanxi Gong, Yi Cao, Xuan Han, Huachang Sun, Jiaxin Li, Yongsheng Tang, Chao Xu","doi":"10.1097/SCS.0000000000012031","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012031","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical efficacy of V-Y subcutaneous pedicle flaps and modified rhomboid flaps for facial tumor resection defect repair.</p><p><strong>Methods: </strong>One hundred three patients were divided into a V-Y subcutaneous pedicle flap group (n=52) and a modified rhomboid flap group (n=51) based on the surgical approach. Total operation time, flap size, postoperative healing time, satisfaction, scar, neurosensory function, and complications were compared.</p><p><strong>Results: </strong>The V-Y subcutaneous pedicle flap group had a smaller flap size (3.51±1.05 versus 3.98±1.01, P=0.023), shorter operation time (24.42±5.02 versus 29.57±5.12, P<0.001), and healing time (6.31±0.86 versus 7.07±1.07, P<0.001). Their visual analogue scale (8.48±1.04 versus 7.93±1.08, P=0.010) and Patient satisfaction score (8.83±0.87 versus 8.36±1.00, P=0.014) were higher. In terms of scar pigmentation (P=0.013), vascularity (P=0.007), pliability (P=0.045), and neurosensory function (P=0.033), it outperformed the modified rhomboid flap group. There was no significant difference in complications (P>0.05).</p><p><strong>Conclusions: </strong>This research discovered that both flap approaches have certain efficacies. In contrast, the V-Y subcutaneous pedicle flap repair modality holds more advantages in clinical therapy. Its level of improvement in clinical therapeutic effects and control of adverse events is superior to that of the modified rhomboid flap.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulwhhab Abu Alamrain, Mohammed Al-Hasan, Bilal Irfan, Ahmed Abuseifan, Majdi Al-Khaldi, Mosab Nassar, Hosam Shaikhkhalil, Abdallah Abu Shammala, Mahmoud Mahani
{"title":"Craniofacial Soft Tissue Injuries in Gaza: Insights from a Plastic Surgeon's Notebook.","authors":"Abdulwhhab Abu Alamrain, Mohammed Al-Hasan, Bilal Irfan, Ahmed Abuseifan, Majdi Al-Khaldi, Mosab Nassar, Hosam Shaikhkhalil, Abdallah Abu Shammala, Mahmoud Mahani","doi":"10.1097/SCS.0000000000012023","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012023","url":null,"abstract":"<p><p>The ongoing Israeli military invasion of the Gaza Strip has dismantled the territory's reconstructive surgery services. This retrospective analysis describes 74 soft tissue facial injuries treated by the plastic-reconstructive department at Al-Aqsa Martyrs' Hospital, Deir Al-Balah, between November 2023 and April 2024. Data were transcribed from a surgeon's handwritten notebook, corroborated with partial hospital records and photographs, anonymized, and analyzed using descriptive statistics plus Mann-Whitney U and the Fisher exact tests. Patients ranged from 2 to 65 years (median: 19.5); 46% were children under 16 and 49% were female. Blast mechanisms accounted for 88% of presentations, producing burns (30%), raw tissue loss (23%), and deep lacerations (22%), with retained shrapnel being documented in 11% of cases. More than half of patients sustained additional systemic injuries, with polytrauma significantly more frequent in females (P=0.0013). Surgical intervention occurred within 24 hours for 85% of cases; 49% involved a reconstructive procedure, most commonly an advancement or rotational flap. Postoperative complications arose in 19% of patients and were dominated by infection and keloid formation, and in-hospital mortality reached 7%, largely from extensive burns and sepsis. Although 97% of those needing higher-level care were referred for medical evacuation, only 54% were able to ultimately exit Gaza. This study showcases the disproportionate pediatric burden, high resource intensity, and evacuation bottlenecks characterizing facial trauma and treatment pathways amid the ongoing military attack and serves to underline the urgency of safeguarding surgical infrastructure and reopening humanitarian corridors.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sibel Özalp, Mehmet Z Erdem, Abdulaziz Yalinkiliç, Abdulmutalip Karaaslanli, Burhan Beger, Bülent Sönmez, Bilal Arslan, Hadice Uçar, Turan Koç, Mitat Selçuk Bozhöyük, Orhan Beger
{"title":"Sella Turcica Dimension and Shape in Trisomy 21: A CT Examination.","authors":"Sibel Özalp, Mehmet Z Erdem, Abdulaziz Yalinkiliç, Abdulmutalip Karaaslanli, Burhan Beger, Bülent Sönmez, Bilal Arslan, Hadice Uçar, Turan Koç, Mitat Selçuk Bozhöyük, Orhan Beger","doi":"10.1097/SCS.0000000000012029","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012029","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to compare the morphologic features of the sella turcica (ST) in patients with trisomy 21 (T21) with a control group.</p><p><strong>Methods: </strong>This retrospective study contained computed tomography images of 45 T21s and 53 controls. Of 45 T21s patients aged 10.31±3.92 years, 21 were females and 24 were males. Of 53 controls aged 12.11±3.91 years, 26 were females and 27 were males. ST shape and size were noted.</p><p><strong>Results: </strong>T21 subjects had statistically greater ST length (P<0.001), anterior height (P=0.004), middle height (P=0.001) and width (P<0.001) than controls, but similar diameter (P=0.098) and posterior height (P=0.097). Six types related to Axelsson classification were noted in T21s with the following frequencies: normal ST (42.2%)>oblique anterior wall (28.9%)>pyramidal shape of the dorsum sellae (15.6%)>double contour of the floor (6.7%)>irregularity (4.4%)>ST bridge (2.2%). Four types regarding this classification were noted in controls with the following frequencies: normal ST (41.5%)>pyramidal shape of the dorsum sellae (34%)>oblique anterior wall (22.6%)>double contour of the floor (1.9%). Three types related to Camp classification were noted in T21s with the following frequencies: round (44.4%)>oval (33.4%)>flattened (22.2%). Three types regarding this classification were noted in controls with the following frequencies: round (49.1%)>oval (37.7%)>flattened (13.2%).</p><p><strong>Conclusion: </strong>Our CT study displays that ST size is affected by T21. However, the ST shape does not correlate with T21.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}