Journal of Craniofacial Surgery最新文献

{"title":"Parent-Reported Health-Related Quality of Life at 3 Years of Age in Children Treated for Sagittal or Metopic Synostosis.","authors":"Marizela Kljajić, Katerina Papadopoulou, Madiha Bhatti Söfteland, Giovanni Maltese, Peter Tarnow, Lars Kölby","doi":"10.1097/SCS.0000000000013491","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013491","url":null,"abstract":"<p><p>Early surgical intervention is recommended for sagittal (SS) and metopic (MS) synostosis to correct head shape and reduce the risk of later social stigmatization. However, the impact of craniosynostosis (CS) and its surgical treatment on health-related quality of life (HRQoL) in early childhood remains insufficiently understood. To evaluate parent-reported HRQoL at 3 years of age in children treated for SS or MS. At the 3-year follow-up, parents of children treated for SS or MS completed the Pediatric Quality of Life Inventory (PedsQL) version 2 to 4 years. Age- and nationality-matched healthy controls were recruited from child health care centers. The study included 138 children treated for CS (SS, n=94; MS, n=44) and 104 controls. Compared with controls, children treated for SS had higher total PedsQL scores (P<0.0001, effect size=0.86) and higher scores in physical, emotional, and social functioning (all P<0.0001; effect sizes 0.58-0.78). Daycare functioning was also significantly higher for SS compared with controls. (P=0.018, effect size=0.34). No significant differences were found between the MS and controls. Compared with the MS group, the SS group had higher total PedsQL scores (P=0.0002, effect size=0.77) and higher scores in physical (P<0.0001, effect size=0.71), emotional (P=0.024, effect size=0.43), social (P=0.0021, effect size=0.62), and daycare functioning (P=0.001, effect size=0.68). At 3 years of age, children treated for SS had higher parent-reported HRQoL than both healthy controls and children treated for MS, whereas children treated for MS did not differ from controls.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The L-Shaped Lateral Crural Graft: A Single-Graft Technique for the Correction of Alar Concavity and Nasal Valve Insufficiency.","authors":"Alper Yenigun, Muhammed F Ozgan, Remzi Dogan, Erol Senturk, Sabri B Eren, Orhan Ozturan","doi":"10.1097/SCS.0000000000013483","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013483","url":null,"abstract":"<p><p>Nasal valve insufficiency and alar concavity are challenging sequelae of previous rhinoplasty, often resulting from a weakened or scar-deformed lateral crus. We describe the L-shaped lateral crural graft, a single autologous costal cartilage construct designed to simultaneously address lateral crural weakness, alar concavity, and nasal valve insufficiency in revision rhinoplasty. The graft is shaped into an L configuration: the long limb is positioned along the lateral crus to reinforce the crus and correct concavity, whereas the short limb is directed dorsally to support the lateral nasal wall and internal nasal valve region. In this single-center consecutive case series, 12 patients (7 male and 5 female; aged 18-55 y) underwent bilateral L-shaped lateral crural grafting, with a mean follow-up of 9.5 months. All patients reported improved nasal breathing and expressed satisfaction with the outcome. Clinical examination revealed increased lateral nasal wall support, and photographic assessment demonstrated reduced alar concavity with improved contour and symmetry. No infection, graft exposure, visibility, contour irregularity, asymmetry, warping, resorption, or recurrent collapse was observed. The L-shaped lateral crural graft may be a feasible option for simultaneous functional and aesthetic correction in selected revision cases, although larger comparative studies using validated outcome measures are warranted.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bleeding Control in Zygomatic Aneurysmal Bone Cysts: Intraoperative Ligation as an Alternative to Preoperative Embolization.","authors":"Orhan Ozturan, Emre Polat, Cagri Yildiz, Remzi Dogan","doi":"10.1097/SCS.0000000000013501","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013501","url":null,"abstract":"<p><strong>Objectives: </strong>Zygomatic aneurysmal bone cysts (ABCs) are rare lesions that may lead to significant intraoperative bleeding. Although preoperative selective arterial embolization (SAE) is often recommended for hemorrhage control, it may not always be feasible. This report explores intraoperative external carotid artery (ECA) ligation as a potential alternative.</p><p><strong>Methods: </strong>A 30-year-old female with a 4×3×3 cm hypervascular ABC of the zygomatic arch underwent surgical excision under general anesthesia. Intraoperative proximal ECA ligation was performed to control bleeding. A review of the literature was conducted for comparison.</p><p><strong>Results: </strong>ECA ligation enabled near-bloodless resection with no major complications. Facial nerve weakness resolved within 3 months. No recurrence was observed at the 4-month follow-up. Among the 10 published zygomatic ABC cases, only 2 featured lesions ≥4 cm with documented hypervascularity, and both underwent preoperative embolization. No prior case involved intraoperative ligation.</p><p><strong>Conclusions: </strong>Intraoperative ECA ligation may be a safe and effective alternative to selective arterial embolization in selected craniofacial ABCs, mainly where embolization is unavailable.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Dimensional Evaluation of Mandibular Asymmetry in Adult Violin and Viola Players: A Prospective Cone-Beam Computed Tomography Study.","authors":"Yong Uk Jung, Sungah Kim, Jeong-Min Hong, Jaewoo Kim","doi":"10.1097/SCS.0000000000013477","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013477","url":null,"abstract":"<p><p>Long-term violin and viola performances involve sustained asymmetric loading of the craniofacial skeleton; however, their association with 3-dimensional mandibular asymmetry has not been well characterized. This prospective study aimed to evaluate mandibular asymmetry using cone-beam computed tomography (CBCT) in adult violin and viola players who have undergone prolonged intensive musical training since childhood. We prospectively included 20 adult violin and viola players, enrolled in or who graduated from the College of Music, Seoul National University. Participants underwent standardized questionnaire-based assessments, including playing history, practice characteristics, and playing-related musculoskeletal symptoms. Three-dimensional CBCT images were reconstructed following standardized reorientation. Bilateral mandibular morphology was evaluated using linear measurements (condylion-gonion, mandibular notch-gonion, and gonion-menton distances), hemimandibular volume, and asymmetry indices (AI). Associations between mandibular asymmetry and questionnaire-derived playing-related variables were analyzed using univariate regression analyses. Handspan measurements were collected as secondary outcome measures to evaluate skeletal laterality associated with prolonged unilateral hand training, providing an additional indicator of musculoskeletal adaptation beyond the craniofacial skeleton. Three-dimensional CBCT demonstrated right-sided predominance in the condylion-gonion distance, mandibular notch-gonion distance, and hemimandibular volume. The gonion-menton distance showed a small, nonsignificant, left-sided predominance. All hand measurements showed a left-sided predominance. No playing-history variable was significantly associated with directional side differences. Adult violin and viola players exhibited characteristic 3-dimensional mandibular asymmetry, with a right-sided predominance of the ramus and hemimandibular volume, accompanied by left-sided hand-span dominance. These findings suggest that prolonged asymmetric mechanical loading during intensive musical training may contribute to adaptive skeletal laterality.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Based Differences in Mortality Following Craniomaxillofacial Trauma: A Retrospective Cohort Study From a Puerto Rico Trauma Center.","authors":"Jan M Ruiz-Núñez, Raúl Y Ramos-Sánchez, Marlene D Rivera-Ferrer, Karla P Vélez-Mojica, Victor J Colón Sánchez, Yaritza Negrón Vélez, Enoli Crespo, Jose G Rosa-Colón, Bryan M Ruiz-Oquendo, Yanizbeth Yambó-Chévere, Ángel Rivera-Barrios","doi":"10.1097/SCS.0000000000013426","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013426","url":null,"abstract":"<p><p>Craniomaxillofacial trauma is a significant public health concern because of its association with severe injuries, long-term morbidity, and mortality. This study evaluated sex-based differences in trauma severity, length of hospital stay, and mortality among patients with craniomaxillofacial (CMF) trauma in Puerto Rico. This retrospective cohort study used electronic medical records from a trauma center in Puerto Rico from January 2018 to October 2022. Data collected included demographics, Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), length of hospital stay, comorbidities, and survival outcomes. Statistical analyses included the χ2 test and t tests to evaluate sex-based differences. Multivariable logistic regression was used to assess the independent association between sex and in-hospital mortality. A total of 1161 patients were included in the study, comprising 960 males and 201 females. Males demonstrated higher in-hospital mortality than females (12.7% versus 6.5%; P=0.012) and presented with lower GCS and RTS scores. Motor-vehicle accidents were the most common mechanism of injury, with males more frequently involved in noncar incidents and females more commonly injured in car accidents. In the fully adjusted model including comorbidities, male sex was independently associated with in-hospital mortality (aOR: 3.73, P=0.014). Lower GCS was the strongest predictor of mortality. These findings suggest that the male sex is associated with increased mortality following CMF trauma after adjusting for injury severity and comorbid burden, highlighting the potential importance of incorporating sex into trauma risk stratification and prevention strategies.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Flap Rotation and Switch in Treating Pediatric Isolated Unilateral Lambdoid Craniosynostosis (4 Cases Report and Literature Review).","authors":"Pingping Gao, Yunhai Song, Zeyang Xia, Xu Kang, Bo Yang","doi":"10.1097/SCS.0000000000013434","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013434","url":null,"abstract":"<p><strong>Objective: </strong>To summarize the clinical experience of pediatric isolated unilateral lambdoid craniosynostosis treated with bone flap rotation and switch.</p><p><strong>Methods: </strong>Clinical data of pediatric patients with isolated unilateral lambdoid craniosynostosis treated with bone flap rotation and switching from October 2019 to October 2023 were retrospectively studied. The clinical characteristics, surgical pearls, and their effects were analyzed.</p><p><strong>Results: </strong>Four patients underwent bone flap rotation and switch procedures to remodel the posterior calvarial. No adverse events or complications were noted. The vault contour significantly improved, with 3 months to 4 years of follow-up.</p><p><strong>Conclusions: </strong>In treating pediatric isolated unilateral lambdoid craniosynostosis, bone flap rotation and switch was an appropriate procedure because of its definite effect, simultaneous cranioplasty, and skull cavity enlargement.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Medicare and Medicaid Physician Fee and Facility Pricing Reimbursements for Craniofacial Trauma Procedures From 2007 to 2024.","authors":"Khoa Nguyen, Celia J Ernstrom, Anna Lee, Ariel Johnson, Mark Greyson, David Mathes, Christodoulos Kaoutzanis, Joseph Lopez, Phuong Nguyen, Jason W Yu","doi":"10.1097/SCS.0000000000013459","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013459","url":null,"abstract":"<p><p>Reimbursement trends influence the sustainability of craniofacial trauma practices, yet limited literature addresses long-term patterns. This study evaluates national trends in Medicare physician fees (PF) and facility pricing (FP) for craniofacial trauma procedures from 2007 to 2024. Reimbursement data were obtained from the Medicare Physician Fee Schedule Look-Up (MPFS) tool by the Centers for Medicare & Medicaid Services (CMS). Craniofacial trauma surgeries were identified using Current Procedural Terminology (CPT) codes. PF values were calculated using national payment amounts, incorporating work, practice expense, and malpractice relative value units with Geographic Practice Cost Indices set to 1.000. Conversion factors were obtained from CMS. PF calculations followed the standard CMS reimbursement formula. FP data were also retrieved from MPFS and adjusted for inflation using the Consumer Price Index. Percentage change and year-over-year (YOY) analyses were performed. Fifty-six CPT codes were analyzed. From 2007 to 2024, average PF reimbursement declined by 26.65%. The smallest decrease occurred with CPT 21485, closed treatment of temporomandibular dislocation (-2.58%), while CPT 21315, closed reduction of a nasal bone fracture, showed the largest (-70.45%). Facility pricing (FP) declined by 19.84%, with 95% of codes experiencing an average net decrease of 21.65%. Only 5% of codes saw an average increase of 12.17%. Closed reduction of a nasal bone fracture had the greatest FP reduction (-68.44%), while CPT 21452, external fixation of a mandibular fracture, had the highest increase (19.16%). YOY changes corresponded with major economic events, including the 2007 to 2008 financial crisis and the 2020 to 2021 SARS-CoV-2 pandemic. Craniofacial trauma reimbursement through Medicare declined markedly between 2007 and 2024, with volatility during key economic periods, emphasizing the need for proactive reimbursement advocacy.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative Strategies for Traumatic Dental Injuries in Craniofacial Trauma: A Narrative Review.","authors":"Guo-Huai Li, Yao Wu, Cheng-Lin Wang","doi":"10.1097/SCS.0000000000013476","DOIUrl":"10.1097/SCS.0000000000013476","url":null,"abstract":"<p><strong>Background: </strong>Traumatic dental injuries are an important component of craniofacial and dentoalveolar trauma and may compromise oral function, facial aesthetics, alveolar support, and long-term tooth preservation, particularly in young patients. They can lead to disruption of pulpal blood supply, pulp necrosis, and periapical tissue damage; in immature permanent teeth with open apices and thin root walls, infection control must be balanced against preservation of further root development.</p><p><strong>Methods: </strong>Within the broader context of craniofacial trauma, this narrative review summarizes the indications, operative procedures, scaffold materials, clinical efficacy, influencing factors, imaging assessment, and multidisciplinary role of REPs as a tooth-preservation strategy for crown/root fractures, luxation injuries, and replanted avulsed teeth.</p><p><strong>Results: </strong>In traumatized immature permanent teeth, REPs achieved an overall success rate of approximately 80%, with symptom resolution, periapical healing, and continued root development in most cases, whereas outcomes were less favorable for avulsed and replanted teeth.</p><p><strong>Conclusion: </strong>In summary, REP may provide a biological-based dental preservation option for selected traumatized teeth, although standardized case selection, treatment plans, and long-term follow-up remain crucial.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidermal Inclusion Cysts With Cranial Bony Erosion Mimicking Dermoid Cysts: A Diagnostic Pitfall - A Series of 4 Patients.","authors":"Soo Hyun Woo, In Ho Jung, Su Yong Kim, Woo Ju Kim, Shin Hyuk Kang, Han Koo Kim, Tae Hui Bae","doi":"10.1097/SCS.0000000000013289","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013289","url":null,"abstract":"<p><p>Craniofacial cystic lesions with underlying bony erosion are classically associated with dermoid cysts, while such involvement by epidermal inclusion cysts (EICs) is considered rare. The authors retrospectively reviewed 4 patients (ages 1-31 y) who underwent excision of craniofacial cysts with bony erosion. All lesions occupied deep tissue planes-including the subtemporoparietal fascia, submuscular, or subgaleal spaces-with firm adhesions to the underlying skeleton. Although preoperative imaging suggested dermoid cysts in all cases, final histopathology confirmed EIC. This series demonstrates that cranial bony erosion is not pathognomonic for dermoid cysts; EICs in deep enclosed planes can induce bony remodeling through chronic mechanical pressure. EIC should be included in the differential diagnosis of any craniofacial cystic lesion with bony erosion, and mandatory histopathological examination remains essential for definitive diagnosis.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI in Fixed Prosthodontics: A Bibliometric and AI-Assisted Qualitative Analysis of Research Trends and Translational Gaps (2011-2026).","authors":"Dan Li, Zixuan Liu, Bin Luo, Jiangqi Hu, Qingsong Jiang","doi":"10.1097/SCS.0000000000013406","DOIUrl":"https://doi.org/10.1097/SCS.0000000000013406","url":null,"abstract":"<p><strong>Background: </strong>A comprehensive understanding of the global research trends and translational gaps in AI for fixed prosthodontics remains limited. This study aimed to characterize research trends, delineate thematic clusters, and identify translational gaps in AI for fixed prosthodontics using an integrated bibliometric and AI-assisted qualitative synthesis framework.</p><p><strong>Methods: </strong>A bibliometric analysis was conducted using the Web of Science Core Collection (2011-2026). A total of 519 records were retrieved and manually screened, yielding 377 eligible publications for quantitative analysis. Five highly cited core papers and 11 keyword clusters were further subjected to cross-model qualitative comparison using 4 large language models: GPT-5.2, Gemini-3 Pro, Claude-4.5 Sonnet, and DeepSeek Latest. Keyword co-occurrence, cluster, and temporal trend analyses were performed. The 4 AI systems were independently prompted to synthesize qualitative findings, and their outputs were compared for thematic convergence and divergence.</p><p><strong>Results: </strong>Keyword analysis revealed the top 3 terms as \"artificial intelligence,\" \"deep learning,\" and \"dentistry,\" indicating AI applications concentrate in the preoperative phase. Co-occurrence analysis identified clusters centered on deep learning, digital dentistry, 3D printing, and AI, suggesting convolutional neural networks and generative adversarial networks have extensively influenced prosthesis manufacturing. The 4 AI systems converged on deep learning as central but diverged in emphasis: GPT-5.2 produced the most integrated clinical narrative; Gemini-3 Pro maintained question-anchored thematic grouping; Claude-4.5 Sonnet applied evidence grading; and DeepSeek prioritized cluster-literature linkage to infer research gaps.</p><p><strong>Conclusions: </strong>Our findings indicate a rapidly accelerating, increasingly interdisciplinary domain transitioning from proof-of-concept toward clinical validation. While predictive and detection models predominate, generative AI demonstrates promising potential for crown design. Future progress should prioritize standardized benchmarking, robust external validation, and workflow-level translation into clinical decision-support. The integration of multiple AI models for qualitative synthesis offers a novel approach to identifying research trends and gaps.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}