Gi-Woong Hong, Isaac Kai Jie Wong, Jong Keun Song, Jesper Thulesen, Ka Fai Wong, Kyu-Ho Yi
{"title":"Anatomy-Based Filler Injection Techniques for the Forehead.","authors":"Gi-Woong Hong, Isaac Kai Jie Wong, Jong Keun Song, Jesper Thulesen, Ka Fai Wong, Kyu-Ho Yi","doi":"10.1097/SCS.0000000000012003","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012003","url":null,"abstract":"<p><p>Forehead filler injections have become a popular nonsurgical approach to enhance facial aesthetics by correcting volume deficiencies and improving contours. This anatomy-based approach emphasizes the importance of understanding the complex structural components of the forehead, including fat compartments, muscles, and vascular pathways. Proper diagnosis of forehead depressions-categorized as central, bilateral, mixed, or total types-guides targeted treatment strategies using submuscular or subdermal injection planes. Submuscular injections provide structural support, minimizing risks associated with superficial placement, such as uneven distribution and vascular complications. Techniques tailored to specific anatomic features, particularly in East Asian patients who often present with narrower foreheads, ensure natural and balanced results. Fillers used in this paper are Hyaluronic Acid (Maili, Sinclair) and Polycaprolactone (Ellanse, Sinclair). Combining fillers with botulinum toxin injections can address both dynamic and static wrinkles, achieving comprehensive facial rejuvenation while maintaining natural expressions, which is especially true for Polycaprolactone biostimulator fillers. This integrated approach optimizes aesthetic outcomes and enhances patient satisfaction by delivering smooth, contoured, and youthful forehead appearances. Level of Evidence: Level V.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeewanjot S Grewal, Wesley McIlwain, Christopher Shumrick, Weitao Wang, Bridget Vories, Yadranko Ducic
{"title":"Facial Nerve Grafting Efficacy With Medial Antebrachial Cutaneous Nerve Cable Grafts in the Setting of Radiation Therapy.","authors":"Jeewanjot S Grewal, Wesley McIlwain, Christopher Shumrick, Weitao Wang, Bridget Vories, Yadranko Ducic","doi":"10.1097/SCS.0000000000012036","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012036","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the facial nerve cable graft reconstruction functional outcomes using the medial antebrachial cutaneous (MABC) nerve within previously irradiated surgical fields compared with facial nerve reconstruction receiving adjuvant radiotherapy.</p><p><strong>Materials and methods: </strong>A retrospective review of patients requiring a radical parotidectomy between 1998 and 2020 with immediate facial nerve reconstruction using the MABC nerve. Patients were divided in 2 groups, the previously irradiated salvage radical parotidectomy group (group 1) and the radical parotidectomy requiring adjuvant radiotherapy (group 2). The House-Brackmann (HB) system was used to assess facial functional results, with a minimum of 18 months of follow-up. A postoperative HB score of I-III was considered a successful outcome.</p><p><strong>Results: </strong>Thirty-two patients were included, with 8 patients in group 1 and 24 patients in group 2. Overall, 25/32 (78.1%) of patients achieved a HB score III, with 7/8 (85%) in group 1 and 18/24 (75%) in group 2. There was no difference in functional outcomes (HB score). There were no donor site complications reported.</p><p><strong>Conclusions: </strong>The MABC nerve is a reliable nerve for facial nerve cable graft reconstruction, and a good functional result (HB III) was achieved in most patients with previously irradiated surgical fields and/or requiring radiotherapy.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Indication in Thyroid Nodules ≥4 cm: Do Larger Nodules Carry Higher Malignancy and Complication Risks?","authors":"Firat Aslan, Serhat Binici, Orhan Beger, Iklil Eryilmaz, Veysel Tahiroğlu, Değercan Yeşilyurt, Emre Teke, Burhan Beger, Recep Güleç, Mehmet Ç Kotan","doi":"10.1097/SCS.0000000000012045","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012045","url":null,"abstract":"<p><strong>Objective: </strong>The management of thyroid nodules is outlined in various clinical guidelines. While the American Thyroid Association guideline provides more systematic algorithms for thyroid nodules smaller than 4 cm in diameter, there is no consensus on the management of nodules ≥4 cm. This study aims to contribute to this topic by evaluating the clinical data of patients who underwent thyroidectomy for nodules measuring ≥4 cm.</p><p><strong>Methods: </strong>This study included 199 patients who underwent thyroidectomy due to thyroid nodules measuring ≥4 cm in diameter. Patients were evaluated based on age, sex, preoperative, postoperative day 1, and at least 1-month postoperative calcium (Ca) and parathyroid hormone (PTH) levels, maximum nodule diameter, fine-needle aspiration biopsy (FNAB) status, and final pathology data.</p><p><strong>Results: </strong>A total of 199 patients (28 men, 171 women; mean age: 46.52±13.82 y) were included in the study. Malignancy was identified in 17.6% of the cases. Nodule size was significantly larger in male patients (P=0.017) and in malignant lesions, particularly those ≥4 cm. FNAB was performed in 39.2% of the patients; there was no statistically significant association between FNAB performance and age group, sex, or pathology results. However, false-negative FNAB results were detected in 25% of malignant cases, indicating the limited sensitivity of FNAB, especially in nodules ≥4 cm.</p><p><strong>Conclusion: </strong>Thyroid nodules measuring ≥4 cm may warrant surgical intervention regardless of whether FNAB was performed or reported as benign, due to their relatively higher rates of malignancy and associated complications.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Pippich, Luisa Flechtenmacher, Matthias Schwarz, Nils Krautkremer, Herbert Deppe, Klaus-Dietrich Wolff, Andreas M Fichter, Lucas M Ritschl
{"title":"In Vitro Investigation of the Biocompatibility of 6 Different High-Performance Resin-Based Materials for Bone Augmentation and Reconstruction.","authors":"Katharina Pippich, Luisa Flechtenmacher, Matthias Schwarz, Nils Krautkremer, Herbert Deppe, Klaus-Dietrich Wolff, Andreas M Fichter, Lucas M Ritschl","doi":"10.1097/SCS.0000000000011898","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011898","url":null,"abstract":"<p><strong>Introduction: </strong>Reconstructive surgery often addresses severe bone defects that impact patients' lives. While microvascular bone transfer is standard, it has drawbacks. Thus, the focus shifts to using alloplastic grafts, avoiding donor sites. This study evaluates the biocompatibility of generatively printed high-performance resins.</p><p><strong>Materials and methods: </strong>Six printed materials were compared with titanium scaffolds: native PEEK (poly-ether-ether-ketone) and native PEKK (poly-ether-ketone-ketone) as well as the surface-modified materials MBTg (Mimicking Bone Technology) PEEK, BCP-filled PEEK, 4h-argon-etched PEKK, and So_PPSU [polyphenylsulfone with barium sulfate (BaS8O4)]. The scaffolds were CAD/CAM manufactured and individually dimensioned using Fused Layer Manufacturing. Biocompatibility was assessed through cytotoxicity, osteoblast viability, and differentiation assays. Osteoblast colonization and adhesion were examined using fluorescence and electron microscopy.</p><p><strong>Results: </strong>All materials were noncytotoxic (P<0.05). So_PPSU exhibited the highest cell proliferation rates. MBTg PEEK, BCP-filled PEEK, and native PEKK also showed significant increases over time (P<0.05). Alkaline phosphatase activity increased for all materials, with 4h-argon-etched PEKK, MBTg PEEK, and BCP-filled PEEK showing the greatest increases. Microscopy validated these findings.</p><p><strong>Conclusions: </strong>The tested materials were noncytotoxic, with MBTg-functionalized PEEK, 4h-argon-etched PEKK and BCP-filled PEEK showing the best biocompatibility. Furthermore, the study demonstrated the feasibility of a time-saving 3D printing process for the reproducible production of customized and functionally designed medical products.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agustin N Posso, Audrey Mustoe, Micaela Tobin, Manuela Neira, Madeleine Givant, Mohammed Yamin, Maria J Escobar-Domingo, Sarah Karinja, Henry C Vasconez, Bernard T Lee
{"title":"Ketorolac Use and Its Association With Craniofacial Fracture Healing Complications: Propensity Score-Matched Analyses.","authors":"Agustin N Posso, Audrey Mustoe, Micaela Tobin, Manuela Neira, Madeleine Givant, Mohammed Yamin, Maria J Escobar-Domingo, Sarah Karinja, Henry C Vasconez, Bernard T Lee","doi":"10.1097/SCS.0000000000012038","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012038","url":null,"abstract":"<p><strong>Background: </strong>Nonunion is a major complication following craniofacial fracture repair. While ketorolac has been associated with impaired bone healing in other fractures, its effect on craniofacial bones remains unclear. This study evaluated the association between postoperative ketorolac use and nonunion after craniofacial fracture repair.</p><p><strong>Methods: </strong>The TriNetX database was used to identify patients who underwent orbital, nasal, zygomatic, maxillary, and mandibular fracture repair. For each type of fracture, patients were classified into ketorolac-exposed and unexposed (control) cohorts. Propensity score-matching was used to adjust for various nonunion risk factors. The primary outcome was nonunion; secondary outcomes were malocclusion, hardware complications, wound dehiscence, and tooth extraction, assessed at 3, 6, and 9 months.</p><p><strong>Results: </strong>For mandibular fractures, 33,740 patients were included after propensity score matching, with 16,870 in the exposed cohort and 16,870 in the control cohort. At 3 months post-repair, patients with ketorolac use had an increased risk of nonunion (RR 2.35, P<0.001), malocclusion (RR 1.67, P<0.001), hardware complications (RR 2.61, P<0.001), wound dehiscence (RR 2.10, P<0.001), and tooth extraction (RR 1.67, P=0.002) with similar risks observed at 6 and 9 months. For other fracture types (orbital, nasal, zygomatic, maxillary), ketorolac use was not associated with increased nonunion risk, though secondary complications were significantly higher.</p><p><strong>Conclusions: </strong>Postoperative ketorolac use is associated with a significantly increased risk of nonunion after mandibular fracture repair and a higher incidence of secondary complications across all craniofacial fracture types.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimally Invasive Separation of Mid-Palatal Suture Using Piezosurgery: A Novel Type of SARME Assisting Maxillary Expansion in Adults.","authors":"Jiaming Wei, Jie Pan, Liming Yu","doi":"10.1097/SCS.0000000000012017","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012017","url":null,"abstract":"<p><p>Maxillary transverse deficiency (MTD), a common malocclusion, is typically treated with maxillary expansion. However, adult MTD patients often present challenges for skeletal expansion due to matured mid-palatal sutures. To address this, the authors developed a minimally invasive surgical technique utilizing piezosurgery to separate the mid-palatal suture and buccal/lingual bone sutures in the anterior maxilla. Then, the Hyrax expander was used for rapid maxillary expansion (RME). This approach effectively achieves maxillary skeletal expansion with successful mid-palatal suture opening, offering a reliable solution for adult MTD.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global Disparities and Artificial Intelligence in Plastic Surgery: A Narrative Review of Current Applications and Ethical Implications.","authors":"Carlota Gimenez Lynch, Seth Thaller","doi":"10.1097/SCS.0000000000012054","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012054","url":null,"abstract":"<p><p>Global disparities in surgical access remain a major health challenge, with an estimated 5 billion people lacking safe and affordable care. Plastic and reconstructive surgery plays a key role in addressing this gap, particularly through the management of trauma, burns, and congenital conditions such as cleft lip and palate. Although nonprofit organizations and surgical mission trips have delivered high procedure volumes, low- and middle-income countries (LMICs) continue to face substantial unmet need. Concerns over sustainability, long-term outcomes, and reliance on foreign teams highlight the importance of building local capacity, yet workforce shortages and infrastructure limitations remain significant barriers. Artificial intelligence (AI) offers a potential avenue for innovation. In high-income countries, AI has been applied to preoperative planning, postoperative monitoring, patient education, and workforce training. These tools could benefit LMICs by reducing reliance on personnel, improving health literacy, optimizing costs, and supporting surgical training. However, challenges such as data poverty, algorithmic bias, unequal access, and weak regulatory structures raise concerns that AI may widen rather than narrow disparities if not implemented thoughtfully. In addition, ethical considerations regarding equity, inclusion, sustainability, safety, and accountability must be addressed. This narrative review synthesizes emerging evidence at the intersection of plastic surgery, global disparities, and AI. The authors outline opportunities where AI may enhance equity and where it may exacerbate inequities, as well as the ethical considerations critical for its safe and sustainable integration.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiao-Ling Li, Zhong-Cheng Bai, Zong-Yan Yang, Xing-Yue Wu, Ya-Yu Wang, Yu-Yu Yan, Lei Yan
{"title":"Retrospective Analysis of Tooth Extractions by Age and Tooth Position in Maxillofacial Surgery Patients.","authors":"Xiao-Ling Li, Zhong-Cheng Bai, Zong-Yan Yang, Xing-Yue Wu, Ya-Yu Wang, Yu-Yu Yan, Lei Yan","doi":"10.1097/SCS.0000000000012013","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012013","url":null,"abstract":"<p><p>This study aimed to investigate the associations between tooth extraction, age, and tooth position from both maxillofacial surgical and orthodontic perspectives. We utilized data collected from civilian patients treated at the Department of Oral and Maxillofacial Surgery of the hospital between March 2019 and January 2020. Data on 2098 extracted teeth were retrospectively analyzed. Impacted teeth were the most common reason for tooth extraction, while periodontitis was the only reason more frequently observed in male patients than in female patients. The peak age range for tooth extraction was 21 to 40 years, with female patients being more than twice as likely as male patients to undergo the procedure. Molars were the most frequently extracted teeth, and apart from third molars, more extractions were performed in female patients than in male patients, with the difference being <20%. The relationship between reasons for extraction and age demonstrated that impacted teeth were primarily extracted in individuals under 50 years of age, whereas periodontitis was more frequently observed in those aged 50 years or older. Over 40% of extractions due to periodontitis and residual roots and crowns involved the first and second molars. Extractions of these molars were predominantly observed in individuals aged 50 years and older, reflecting degenerative maxillofacial changes. The bimodal distribution revealed young patients needing combined orthodontic-surgical impaction management and older adults requiring periodontal rehabilitation. These findings advocate for integrated care-orthodontists ensuring proper eruption and occlusion, while surgeons address complex extractions and rehabilitation-to optimize lifelong dentofacial health.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nonsurgical Management of Syndrome of the Trephined: A Systematic Review.","authors":"Brian Paul, Garrison Leach, Travis C Holcombe","doi":"10.1097/SCS.0000000000012042","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012042","url":null,"abstract":"<p><p>Syndrome of the Trephined (SoT), also known as sunken or sinking skin flap syndrome (SSFS), is a rare sequela of decompressive craniectomy caused by an atmospheric pressure gradient over the underlying brain parenchyma following bone flap removal. Cranioplasty is the definitive treatment of SoT, although some patients are not surgical candidates or require bridging to definitive treatment. This systematic review identified 7 articles describing nonsurgical interventions for patients with SoT. Three treatment modalities emerged: external orthotics, scalp traction, and Trendelenburg positioning. These approaches demonstrated rapid improvements in neurological symptoms, including restored motor function, improved cognition, resolution of midline shifts, and, in some cases, re-expanded brain parenchyma. While these results are limited to case reports and small case series, they demonstrate promising early outcomes for the noninvasive management of Syndrome of the Trephined.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Case Handling and Experience Sharing for Venous Congestion Following Free Flap Graft.","authors":"Shi-Long Zhang, Hou-Fu Xia, Jia Jun, Zi-Li Yu","doi":"10.1097/SCS.0000000000012032","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012032","url":null,"abstract":"<p><strong>Background: </strong>Venous congestion is a common complication following free flap transplantation, yet its natural progression and optimal management strategies remain poorly understood. Early-stage venous congestion is often misdiagnosed as venous crisis, leading to unnecessary flap removal. This study aims to elucidate the clinical course and treatment outcomes of venous congestion in anterolateral thigh (ALT) perforator flaps.</p><p><strong>Methods: </strong>Two cases of squamous cell carcinoma (SCC) patients who underwent ALT flap reconstruction after tumor resection were retrospectively analyzed. Postoperatively, both flaps exhibited venous congestion despite patent arterial and venous anastomoses. Bloodletting therapy using low-molecular-weight heparin (LMWH) was instituted to alleviate congestion. Clinical progression, treatment protocols, and flap outcomes were meticulously documented.</p><p><strong>Results: </strong>Following LMWH-based bloodletting therapy, venous congestion significantly improved in both cases. New microcirculation was established within the flaps, evidenced by gradual resolution of purple discoloration, reduced swelling, and formation of granulation tissue. Full flap survival was achieved in both patients by postoperative day 42, with no secondary surgeries required.</p><p><strong>Conclusions: </strong>Conservative management with LMWH bloodletting therapy effectively resolves venous congestion in ALT flaps, promotes microcirculatory regeneration, and prevents flap necrosis. This approach offers a viable alternative to surgical re-exploration, reducing patient morbidity. Our findings underscore the importance of early recognition and targeted intervention for venous congestion, providing valuable insights for optimizing flap salvage protocols.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}