Journal of Craniofacial Surgery最新文献_第4页

Recurrent Infraorbital Rim Osteoma in a Pediatric Patient: A Brief Report. 1例小儿眼眶下骨瘤复发：简要报告。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-11 DOI: 10.1097/SCS.0000000000012933

Ersin Kiliç, Hasan Murat Ergani, Büşra Taş Efe, Emre Saybaşi, Ziya Öğüt, Burak Yaşar, Ramazan Erkin Ünlü

{"title":"Recurrent Infraorbital Rim Osteoma in a Pediatric Patient: A Brief Report.","authors":"Ersin Kiliç, Hasan Murat Ergani, Büşra Taş Efe, Emre Saybaşi, Ziya Öğüt, Burak Yaşar, Ramazan Erkin Ünlü","doi":"10.1097/SCS.0000000000012933","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012933","url":null,"abstract":"Orbital osteomas are rare benign tumors, and infraorbital rim involvement is particularly uncommon in pediatric patients. Recurrence after prior excision has been documented only rarely. The authors report a 14-year-old boy with a recurrent osteoma of the left infraorbital rim after previously reported complete excision at an outside institution. On examination, the lesion presented as a firm, painless, well-circumscribed mass without diplopia, proptosis, or visual disturbance. Computed tomography demonstrated a well-defined hyperdense bony lesion arising from the infraorbital rim. Re-excision was performed through a subciliary approach, and histopathologic examination again confirmed compact osteoma. No further recurrence was observed during follow-up. This case demonstrates that infraorbital rim osteomas, which are rare in pediatric patients, may recur even after previously reported complete excision. Careful removal of the lesion together with its periosteal attachment and long-term clinical and radiologic follow-up should be considered in growing patients.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147868693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Florid Cemento-Osseous Dysplasia Complicated By Periapical Inflammation: A Clinical Case Analysis and Systematic Review of Diagnostic Challenges. 伴有根尖周围炎症的骨质增生异常：一个临床病例分析和诊断挑战的系统回顾。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-08 DOI: 10.1097/SCS.0000000000012425

Jiantao Xu, Jing Lei, Yongli Bi

引用次数: 0

CD39+ Activated Tregs in Cutaneous Squamous Cell Carcinoma: Insights From a Mendelian Randomization and Flow Cytometry Study. CD39+激活的Tregs在皮肤鳞状细胞癌：孟德尔随机化和流式细胞术研究的见解。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-08 DOI: 10.1097/SCS.0000000000012835

Chao Lian, Hanghang Zhou, Ruina Jin, Xuanfen Zhang

{"title":"CD39+ Activated Tregs in Cutaneous Squamous Cell Carcinoma: Insights From a Mendelian Randomization and Flow Cytometry Study.","authors":"Chao Lian, Hanghang Zhou, Ruina Jin, Xuanfen Zhang","doi":"10.1097/SCS.0000000000012835","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012835","url":null,"abstract":"Cutaneous squamous cell carcinoma is a common keratinocyte-derived malignancy shaped by the immune microenvironment. Regulatory T cells are essential for maintaining immune balance, yet within tumors, they suppress protective immunity and promote cancer progression. The contribution of specific subsets of these cells to cutaneous squamous cell carcinoma remains unclear. In this study, we combined genetic causal inference with blood-based immune profiling to investigate the role of CD39-expressing regulatory T cells. Peripheral blood samples from patients and healthy controls were analyzed by flow cytometry, which revealed an increased frequency of activated regulatory T cells in patients. Using genome-wide association study data, Mendelian randomization analyses identified a causal relationship between genetically predicted CD39-positive regulatory T cells and risk of cutaneous squamous cell carcinoma. In an independent validation cohort, the proportion of CD39-expressing cells within the activated regulatory T cell population correlated with higher tumor stage and disease progression. These findings demonstrate that CD39-positive regulatory T cells constitute a distinct immunosuppressive subset with clinical relevance. By integrating immunophenotyping, genetic inference, and validation in patient samples, this study provides novel evidence for the role of CD39-positive regulatory T cells in cutaneous squamous cell carcinoma and supports their potential as selective targets for future immunotherapy.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147868585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Correction of Large Frontal Osteoma and Small Nose Using Calvarial Bone and Pericranial Graft. 颅骨及颅周移植同时矫正大额骨瘤及小鼻。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-08 DOI: 10.1097/SCS.0000000000012910

Jung Ho Lee, Da Yoon Kwon, Daiwon Jun

引用次数: 0

Mandibular Distraction Osteogenesis in Monozygotic Twins With Structural-Dominant ALG8 Variants. 结构显性ALG8变异的同卵双胞胎下颌牵张成骨。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-08 DOI: 10.1097/SCS.0000000000012872

Xingyu Xia, Shigui Lu, Jinlong Zou, Chuanzhi Wang, Weimin Shen

引用次数: 0

Composite Facial Defect Reconstruction With Patient-Specific Implant After Electrical Burn Injury. 电烧伤后患者特异性种植体复合面部缺损重建。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-07 DOI: 10.1097/SCS.0000000000012857

Soham Shah, Tushar Patil, Raghav Shrotriya, Rahul Jain, Sanjay Mahendru

引用次数: 0

An Exceptionally Large Mixed Laryngocele Presenting as a Cervical Mass. 异常大的混合性喉囊肿表现为颈部肿块。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-07 DOI: 10.1097/SCS.0000000000012881

Nikolaos Lazaridis, George Trikoilis, Frinta-Maria Aidoni, George Triantafyllou, Μaria Piagkou, Elpida Chochliourou

{"title":"An Exceptionally Large Mixed Laryngocele Presenting as a Cervical Mass.","authors":"Nikolaos Lazaridis, George Trikoilis, Frinta-Maria Aidoni, George Triantafyllou, Μaria Piagkou, Elpida Chochliourou","doi":"10.1097/SCS.0000000000012881","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012881","url":null,"abstract":"Laryngoceles are rare benign dilatations of the laryngeal saccule that communicate with the laryngeal lumen and may present with variable clinical manifestations depending on their size and extent. Their presentation can range from incidental findings to clinically significant cervical masses or airway-related symptoms. The authors report a case of an unusually large mixed laryngocele in a 62-year-old male who presented with progressive right-sided cervical swelling, dysphagia, and throat discomfort. Computed tomography revealed a well-defined air-filled lesion arising from the laryngeal ventricle with extension into the right cervical region, consistent with a mixed laryngocele, resulting in displacement of the airway. The patient underwent successful surgical excision through an external transcervical approach. Histopathologic examination confirmed the diagnosis, demonstrating a cyst lined by pseudostratified ciliated respiratory epithelium. The postoperative course was uneventful, with complete resolution of symptoms on follow-up. This case is notable for the lesion's size and its prominent cervical presentation, both of which are uncommon in routine clinical practice. It emphasizes the importance of accurate diagnosis, exclusion of underlying malignancy, and appropriate surgical planning in achieving complete excision and favorable outcomes, particularly in large or combined laryngoceles.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics and Evaluation of Treatment Outcomes in Traumatic Eyelid Lacerations in the Geriatric Population. 老年人外伤性眼睑撕裂伤的临床特点及治疗效果评价。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-06 DOI: 10.1097/SCS.0000000000012875

Ömer Özer, Levent Doğan, Zeki Baysal

{"title":"Clinical Characteristics and Evaluation of Treatment Outcomes in Traumatic Eyelid Lacerations in the Geriatric Population.","authors":"Ömer Özer, Levent Doğan, Zeki Baysal","doi":"10.1097/SCS.0000000000012875","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012875","url":null,"abstract":"Background: The aim of this study is to evaluate the demographic characteristics, etiology, clinical outcomes, treatment methods, complications, and functional outcomes of traumatic upper and lower eyelid lacerations in elderly individuals.Methods: At the presentation, the age, gender, affected eye and eyelids, etiology and place of trauma, type of trauma, and any accompanying adnexal injuries were recorded for all patients. Treatment outcomes were analyzed in the early postoperative period (first month) and the late postoperative period (sixth month). The primary endpoint is the restoration of eyelid integrity and the absence of lagophthalmos. Secondary endpoints include the presence of infection, scar formation, entropion or ectropion, and epiphora.Results: Eyelid integrity was achieved in 95.8% (n=46) of patients in the early postoperative period. The lagophthalmos observed in 1 (2.08%) patient in the early period resolved during follow-up. While no cases of entropion or ectropion were observed in patients during the early postoperative period, entropion/ectropion was observed in a total of 4 (8.33%) patients in the later period. Among the 15 (31.25%) patients with lacrimal system injury, epiphora observed in the early postoperative period persisted in 3 (6.25%) patients during follow-up.Conclusion: In conclusion, our study demonstrates that falls are the most common cause of traumatic eyelid injuries in older patients and that these injuries predominantly occur in the home and daily living environments. Developing fall-prevention strategies for elderly patients, performing careful anatomic assessment following trauma, and ensuring long-term follow-up are of great importance for improving both functional and aesthetic outcomes.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Effectiveness Using the Modified Straight Line Closure Method in Unilateral Cleft Lip Patients From April 2015 to April 2025. 2015年4月~ 2025年4月单侧唇裂患者改良直线闭合法的疗效评价

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-06 DOI: 10.1097/SCS.0000000000012545

Abdoljalil Kalantar-Hormozi, Mohammad B Zeydabadi, Mehran Noori, Sakineh Khanamani Falahatipour, Ahmad E Zarch

{"title":"Evaluation of the Effectiveness Using the Modified Straight Line Closure Method in Unilateral Cleft Lip Patients From April 2015 to April 2025.","authors":"Abdoljalil Kalantar-Hormozi, Mohammad B Zeydabadi, Mehran Noori, Sakineh Khanamani Falahatipour, Ahmad E Zarch","doi":"10.1097/SCS.0000000000012545","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012545","url":null,"abstract":"Background: Unilateral cleft lip repair has evolved significantly, with ongoing debate regarding optimal surgical techniques that results on a good scar. While rotation-advancement methods remain prevalent, modern modifications of straight-line approaches offer potential advantages in scar concealment and anatomic preservation.Patients and methods: This prospective study evaluated a modified straight-line closure technique in 90 patients (40 male and 50 female) aged 3 to 24 months with complete (n=35) or incomplete (n=55) unilateral cleft lip. Key technical features included precise anatomic landmark identification, orbicularis oris muscle reconstruction, and alar base stabilization. No transverse or oblique incisions were used on the lip skin from the nostril to the Cupid bow. Outcomes were assessed at 6 months to 10 years postoperatively using anthropometric analysis of standardized photographs by 2 independent plastic surgeons.Results: The technique achieved good symmetry outcomes, with 94.4% of cases showing ≤2 mm philtral column discrepancy and 100% demonstrating ≤2 mm vertical lip height difference. Nasal symmetry was particularly notable (mean alar base discrepancy: 0.68±0.74 mm, P<0.001). Cupid bow proportions (0.27±0.04, P<0.001) and vermilion continuity (88.9% without notching) were well-maintained. No significant differences emerged between complete and incomplete clefts (P>0.05).Conclusion: The modified straight-line approach produces consistent, reproducible outcomes across cleft types, combining the simplicity of traditional straight-line repairs with refinements addressing historical limitations. Its ability to achieve simultaneous labial and nasal correction makes it a valuable alternative to rotation-advancement approaches, particularly when prioritizing scar quality and anatomic subunit preservation.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geometric Morphometric-Based Estimation as an Aid for Naso-Orbito-Ethmoidal Trauma Management. 基于几何形态计量学的估计在鼻眶筛外伤治疗中的应用。

IF 1 4区医学

Journal of Craniofacial Surgery Pub Date : 2026-05-06 DOI: 10.1097/SCS.0000000000012890

Ahmed M El Sergani, Seth M Weinberg

{"title":"Geometric Morphometric-Based Estimation as an Aid for Naso-Orbito-Ethmoidal Trauma Management.","authors":"Ahmed M El Sergani, Seth M Weinberg","doi":"10.1097/SCS.0000000000012890","DOIUrl":"https://doi.org/10.1097/SCS.0000000000012890","url":null,"abstract":"The naso-orbito-ethmoid (NOE) region comprises complex anatomy, and as such, NOE fractures present with a challenge during reconstruction. Restoring the pretraumatic facial form is often challenging, and patients may experience re-deformities. We evaluated 2 computer-aided methods to estimate pretraumatic facial form in silico. A sample of 3D facial images of adult Caucasian males and females was utilized to evaluate 2 geometric morphometric-based facial landmark estimation methods in silico. These include thin-plate spline (TPS) and multivariate regression. Six anthropometric facial landmarks (nasion, pronasale, bilateral endocanthion, and bilateral alare) representing the regional anatomic projections were artificially removed and subsequently estimated based on the location of 18 other landmarks. Between-group principal component analysis was run with permutation testing to uncover impact on facial form between original and estimated landmark configurations. Thin-plate spline-based estimation presented with superior accuracy. Conversely, the regression-based method introduced a statistically significant artificial deformity and was thus excluded from further consideration. Estimation error in the TPS-based method was evaluated by measuring Euclidean distances between the estimated and original landmarks. Mean error was highest at nasion (up to 3.34±1.7 mm). Thin-plate spline-based estimation showed promising accuracy, and the computer-assisted pipeline is time-feasible and yields a 3D-printable aid to be used intraoperatively during reconstructive surgery. Given that the current in silico study that has not been clinically translated yet, our findings, therefore, await replication and future clinical translation.","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0