{"title":"Anatomic Insights for Translational Research in Reconstructive Surgery.","authors":"Kun Hwang","doi":"10.1097/SCS.0000000000011419","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011419","url":null,"abstract":"","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reviving the Past, Moving on to the Present, and Planning for the Future of Craniofacial Malformations.","authors":"Riccardo F Mazzola, Isabella C Mazzola","doi":"10.1097/SCS.0000000000011286","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011286","url":null,"abstract":"<p><p>The malformed newborn with craniofacial anomalies was variously regarded in different civilizations. Some populations considered it a symbol of the presence of God, whereas others brutally eliminated it. Understanding of craniofacial malformations started in the 19th century, with the development of embryological, experimental studies. Management of congenital facial deformities was not mentioned in medical literature until the middle of the 14th century. Ambroise Paré (1510-1590), published the first image of a cleft lip closure in 1561. Priority for cleft palate suture is shared between the German Carl Ferdinand von Gräfe (1787-1840) in 1817 and the Frenchman Philibert Joseph Roux (1780-1854) in 1819. Other examples of correction of congenital facial defects were reported by Jacques M. Delpech (1772-1832), who treated a naso-ocular cleft in 1828, and by John Collins Warren (1778-1856) at Massachussest General Hospital in Boston, who excised a large facial haemangioma, using ether for the first time. The patient had no pain during the whole procedure and the date of October 16, 1846 is best remembered as Ether Day or Death of Pain, opening a new era for modern surgery. Repair of major craniofacial anomalies represents one of the major achievements of plastic surgery of the last decades. In 1967, Paul Tessier (1918-2008), first demonstrated the importance of intracranial access as the sole solution to correct hypertelorism, approximating the abnormally distant orbits along the midline. Tessier also conceived an anatomical classification of craniofacial malformations based on a detailed numbering system. New innovations and technologies are rapidly enriching our practices. Distraction osteogenesis (DO) plays a key role in the surgical correction of malformations of the craniofacial skeleton. Virtual surgical planning (VSP) has transformed the way craniomaxillofacial surgeries are planned and executed. Artificial intelligence (AI) represents a completely new field. It will revolutionize craniofacial surgery in the near future.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Predictive Model for Postoperative Intracranial Infection in Patients Following Spontaneous Intracranial Aneurysm Rupture.","authors":"Zhijuan Wei, Shanshan Han, Shanbing Hou, Dongfang Yu, Yin-Gang Wu","doi":"10.1097/SCS.0000000000011637","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011637","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the risk factors for postoperative intracranial infection in patients with intracranial aneurysm rupture and to use them to construct a predictive clinical model.</p><p><strong>Methods: </strong>A total of 598 patients with intracranial aneurysm rupture admitted to Anhui Provincial Hospital between June 2020 and October 2022 were selected. Univariate and logistic regression analyses were conducted to identify the risk factors for postoperative intracranial infection. A predictive clinical model was constructed, and its effectiveness in clinical applications was systematically evaluated using receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>Among the 598 patients with spontaneous intracranial aneurysm rupture, 71 developed an intracranial infection (11.87%). The results of logistic regression analysis showed that preoperative lung infection, Glasgow Coma Scale (GCS) score at admission, unplanned secondary surgery, surgical method, ventricular haematocele, Hunt-Hess score, and an indwelling drainage tube were factors influencing the development of intracranial infections in patients with spontaneous intracranial aneurysm rupture. The area under the ROC curve (AUC) of the prediction model based on these factors was 0.959, with an optimal critical value of 0.148, a sensitivity of 0.915, and a specificity of 0.907.</p><p><strong>Conclusions: </strong>The authors' predictive model achieved excellent results and can help medical personnel quickly identify the risk of intracranial infection, screen populations with postoperative infection after intracranial aneurysm rupture and provide strategies for the prevention of intracranial infections.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eye Tracking Technology as an Adjunct in Medical Education: Our Experience at the National Paediatric Craniofacial Centre in Ireland.","authors":"Emily A Panteli, Shirley Bracken, Dylan J Murray","doi":"10.1097/SCS.0000000000011457","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011457","url":null,"abstract":"<p><p>Eye-tracking Technology (ETT) measures an individual's eye movements to reflect their attentional behavior. Medicine and surgery are highly visual disciplines, with health care professionals (HCPs) processing visual information in the diagnosis of many conditions, including craniosynostosis. ETT has been applied to the clinical setting in many ways, including in the training and assessment of HCPs. The authors' objectives are to design an education session for HCPs to identify abnormal head shapes associated with non-syndromic craniosynostosis, while utilizing ETT as a learning assessment tool. HCPs and student HCPs were recruited. The Tobii Pro Nano eye tracker was used with iMotions software. Photographs of patients with non-syndromic craniosynostosis were shown, and participants were asked to analyze each photograph for features of craniosynostosis while being monitored by ETT. Participants then attended an education session delivered by a consultant craniofacial surgeon. After the session, participants were shown a different set of photographs of patients with non-syndromic craniosynostosis while being monitored by ETT. Their performance before and after the education session was compared by performing Wilcoxon Signed-Rank tests for several area of interest (AOI) metrics. Seven participants took part in our eye-tracking study. Statistical analysis of AOI metrics revealed that participants improved in several metrics after attending the educational session, including mean dwell count and mean revisit count. The authors' results demonstrate that ETT was a useful adjunct in objectively assessing the effectiveness of their education session. The authors' study is the first to demonstrate the effectiveness of ETT as an educational adjunct in craniofacial conditions.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arezoo Jahanbin, Sara Hafez, Seyed Amir Ali Haj Seyed Alikhani, Farzaneh Lal Alizadeh
{"title":"Relationship Between Cervical Vertebral Development Stages and the Ossification of the Zygomaticomaxillary Suture in Individuals Aged 6-18.","authors":"Arezoo Jahanbin, Sara Hafez, Seyed Amir Ali Haj Seyed Alikhani, Farzaneh Lal Alizadeh","doi":"10.1097/SCS.0000000000011510","DOIUrl":"10.1097/SCS.0000000000011510","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the correlation between ossification of the zygomaticomaxillary suture and cervical vertebral maturation to find the appropriate age for maxillary protraction.</p><p><strong>Method and materials: </strong>This cross-sectional retrospective study was performed on 222 CT scans of patients aged between 6 and 18 (including 161 males and 61 females). Zygomaticomaxillary suture (ZMS) maturation and cervical vertebral maturation (CVM) were assessed in 5 and 6 stages, respectively. The Mann-Whitney, Spearman, Kruskal-Wallis, independent samples T test, and logistic regression were used for data analysis. P <0.05 was considered significant.</p><p><strong>Results: </strong>If a child is at stage 1 in CVM, 87.5% of the time is at stage A in ZMS maturation. In case a child is at stage 2 in CVM, 46.5% of the time is at stage B, and 41.4% is in stage C in ZMS maturation. In case a child is at stage 3 in CVM, 70.8% of the time is at stage C in ZMS maturation. In case a child is at stage 4 in CVM, 64.5% of the time is at stage D in ZMS maturation.</p><p><strong>Conclusion: </strong>According to the fact that patients who are in stages A and B of ZMS maturation respond better to maxillary protraction, it was indicated that if the CVM stage is 1, it is strongly related to stage A of ZMS maturation. Stage 2 in CV maturation can be related to stages B or C of ZMS maturation and CVM stage 3 is highly related to stage C of ZMS maturation.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bharti Gupta, Mahendrakumar A Chaudhari, Harleen Kaur Sohi, Mangesh S Panakaje, Ankita Mathur, Gabriele Cervino, Luca Fiorillo
{"title":"Oral and Maxillofacial Manifestations of Gardner Syndrome: A Literature Analysis.","authors":"Bharti Gupta, Mahendrakumar A Chaudhari, Harleen Kaur Sohi, Mangesh S Panakaje, Ankita Mathur, Gabriele Cervino, Luca Fiorillo","doi":"10.1097/SCS.0000000000011639","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011639","url":null,"abstract":"<p><strong>Background and objective: </strong>Gardner syndrome (GS) is a rare autosomal condition of neoplasms and adenomatous polyps, particularly in the colon and rectum. If left untreated, these polyps develop into colon cancer. Thus, early diagnosis is crucial to improve prognosis among patients. However, the majority of the existing research is limited to single case studies, which lack generalizability. Therefore, this systematic review provides a thorough synthesis of GS-related dental symptoms along with diagnostic and treatment options, and outcomes in the published literature.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted across 2 databases and the Google Scholar search engine. Case reports detailing oral symptoms in GS patients were included. The extracted information was synthesized using descriptive measures (frequencies and percentages) in a tabular format.</p><p><strong>Results: </strong>Of 676 studies, 33 studies were found eligible and evaluated statistically. GS has been investigated in 38 cases, with a larger prevalence among males than females. Mandibular osteomas/odontomas/dermoid cysts were the most frequently reported symptoms (84.21%). Teeth-related symptom was impacted teeth (50%), supernumerary teeth (23.68%), and missing teeth (18.42%). The predominant radiographic findings were osteomas (84.21%), followed by irregular and dense bony regions in the mandible (50%). In 23.68% of cases, osteoma was resected. Teeth extraction was performed in 21.05% of cases. In total, 5.26% had osteoma recurrence.</p><p><strong>Conclusions: </strong>Oral and maxillofacial features can serve as a significant diagnostic indicator for screening and subsequent confirmation of GS in affected patients, allowing for timely referral and care. Dental professionals must be properly trained to identify the dental and maxillofacial manifestations of the disease.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu-Lu Zhou, Zhi-Jie Zhang, Hao Ma, De-Yuan Qu, Gang Chen, Wei Ding, Wen-Bin Dai, Wei Wang, Wen-Jin Wang
{"title":"Research on Establishment Objective Evaluation System of Facial Paralysis Based on Facial Pattern Characteristics.","authors":"Yu-Lu Zhou, Zhi-Jie Zhang, Hao Ma, De-Yuan Qu, Gang Chen, Wei Ding, Wen-Bin Dai, Wei Wang, Wen-Jin Wang","doi":"10.1097/SCS.0000000000011638","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011638","url":null,"abstract":"<p><strong>Background: </strong>Facial paralysis severely impacts patients' quality of life, yet current assessment methods remain subjective, inconsistent, and inefficient. Conventional tools like FACE-gram rely on manual facial landmark identification, which limits accuracy and reproducibility in clinical evaluations.</p><p><strong>Methods: </strong>The authors developed a machine learning-based system that enhances the Dlib framework to enable automatic and precise detection of key facial landmarks, including eyebrows, eyes, nose, and lips. The system integrates TensorFlow for iris detection and applies algorithms such as coordinate system transformation and absolute distance calculation to convert pixel-level data into precise physical measurements, ensuring objective evaluations.</p><p><strong>Results: </strong>The authors' system demonstrated significant improvements in accuracy and efficiency over conventional methods by automating facial landmark detection. Through providing standardized and reproducible assessments, the system establishes a foundation for advancing consistent diagnostic approaches. It also facilitates monitoring during treatment and long-term follow-up, enabling clinicians to comprehensively evaluate and manage facial paralysis across all stages of care.</p><p><strong>Conclusions: </strong>By automating precise facial landmark detection and objective assessment, the authors' machine learning-based system addresses key limitations in current assessment tools. This innovation not only promises to standardize evaluation methods but also holds the potential to transform the clinical management of facial paralysis, ultimately improving outcomes and quality of care for affected patients.</p><p><strong>Level of evidence: </strong>Level IV.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eyelid Reconstruction Using Tenzel Flap Combinated With Glabellar Flap.","authors":"Junho Lee, Da Yoon Kwon, Sung-No Jung","doi":"10.1097/SCS.0000000000011577","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011577","url":null,"abstract":"<p><p>Eyelids constitute a delicate unit of the face, and periorbital defects commonly arise from the wide excision of skin tumors, trauma, or congenital anomalies. Various local flaps, including the glabellar flap, forehead flap, and cheek advancement flap, have been described for reconstruction. The authors present a case of eyelid reconstruction with Tenzel flap combined with glabellar flap to address a sizable medial canthal defect following tumor excision.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yavuz Sultan Selim Yildirim, Sevler Yildiz, Nihat Susaman
{"title":"Comparative Analysis of Postoperative Psychological Well-Being and Quality of Life Following Rhinoplasty and Septorhinoplasty.","authors":"Yavuz Sultan Selim Yildirim, Sevler Yildiz, Nihat Susaman","doi":"10.1097/SCS.0000000000011648","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011648","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare satisfaction levels, quality of life, and psychological well-being in patients who underwent either rhinoplasty or septorhinoplasty-2 procedures that have become increasingly common in recent years.</p><p><strong>Methods: </strong>The study included 98 participants, consisting of 49 individuals who underwent septorhinoplasty and 49 who underwent rhinoplasty. All participants completed a study-specific sociodemographic questionnaire, the Turkish version of the Rhinoplasty Outcome Evaluation Questionnaire (ROE-T), the Beliefs About Appearance Scale (BAAS), the 36-Item Short Form Health Survey (SF-36), the Beck Anxiety Inventory (BAI), and the Beck Depression Inventory (BDI).</p><p><strong>Results: </strong>Participants in the septorhinoplasty group exhibited significantly higher BDI scores, reflecting more pronounced depressive symptoms, whereas those in the rhinoplasty group demonstrated notably elevated BAI scores, indicating greater anxiety levels (P<0.001 and P=0.003, respectively). SF-36 scores, which reflect overall quality of life, were significantly higher in the septorhinoplasty group (P<0.001). No significant difference was found in BAAS scores between the 2 groups (P>0.05). ROE-T scores, indicating satisfaction with surgical outcomes, were significantly higher in the rhinoplasty group (P<0.001). A negative correlation was observed between age and BAI scores (r = -0.204, P = 0.044), as well as between ROE-T and BDI scores (r = -0.627, P<0.001). Furthermore, BDI scores were a significant negative predictor of ROE-T scores (P<0.001).</p><p><strong>Conclusions: </strong>The surgical indication-whether rhinoplasty or septorhinoplasty-can influence patients' postoperative satisfaction, psychological well-being, and quality of life.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of ChatGPT-4o, Claude 3.5 Sonnet, and Google Gemini 2.0 Flash as Patient Education Resources for Upper Blepharoplasty Patients.","authors":"Suleyman Demir, İsmail Cem Türkeş","doi":"10.1097/SCS.0000000000011608","DOIUrl":"https://doi.org/10.1097/SCS.0000000000011608","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness, accuracy, and readability of the leading large language models (LLMs) from 3 different companies, ChatGPT-4o, Claude 3.5 Sonnet, and Google Gemini 2.0 Flash, as patient education resources for upper blepharoplasty.</p><p><strong>Methods: </strong>Twenty frequently asked questions about upper blepharoplasty were posed to the 3 LLMs. Two ophthalmologists recorded the responses to the questions and independently evaluated the accuracy of the LLMs using a 5-point Likert scale with scores ranging from 1 to 5. The readability of the analyzed texts was assessed using the SMOG index and the Coleman-Liau index.</p><p><strong>Results: </strong>All models demonstrated high accuracy, with mean Likert scores exceeding 4.5. No statistically significant difference in Likert scores was observed among the 3 models (P=0.097). Claude 3.5 Sonnet generated the most complex responses (Coleman-Liau index: 17.34; SMOG index: 23.82 points), whereas Google Gemini 2.0 Flash produced the most comprehensible texts (Coleman-Liau index: 13.27; SMOG index: 15.04 points).</p><p><strong>Conclusion: </strong>Large language models hold great promise as tools to educate patients about upper blepharoplasty. Future research should focus on simplifying language models without compromising accuracy, keeping models up-to-date, and minimizing bias to improve patient care and safety.</p>","PeriodicalId":15462,"journal":{"name":"Journal of Craniofacial Surgery","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}